title: Mitral Annular Systolic Velocities Predict Left Ventricular Wall Motion Abnormality During Dobutamine Stress Echocardiography.
abstract: BACKGROUND
  Longitudinal systolic left ventricular contraction is complementary to the radial performance and can be assessed using tissue Doppler imaging (TDI). This study was performed to evaluate the contribution of mitral annular systolic velocities using TDI after dobutamine stress echocardiography (DSE).
  
  
  RESULTS
  Fifty subjects with suspected coronary artery disease and chest pain were examined, using DSE as usual, as well as TDI imaging of the mitral annulus at the septal, lateral, inferior, anterior, posterior regions and the proximal anteroseptal region from the apical views, before and immediately after DSE. In 24 subjects the study was normal, while wall motion abnormality was seen in 26, 9 of them only after DSE. Mitral annular systolic velocity at the 6 locations increased significantly after DSE both in normal subjects and in those with wall motion abnormality (WMA). After DSE mitral annular septal systolic velocity in normals, 19.2 ± 3.8 cm/sec, was higher than in those with WMA, 14.6 ± 2.5 cm/sec, P < 0.0003. Post-DSE mitral systolic velocity was senstive and accurate in predicting WMA.
  
  
  CONCLUSIONS
  Systolic mitral TDI velocities increase after DSE, however to a lesser extent in those with wall motion abnormality, and can differentiate them from normal subjects.
authors.affiliation: Department of Cardiology, Bnai Zion Medical Center, Haifa, Israel; Technion - Israel Institute of Technology, Haifa, Israel.
authors.forename: Dawod
authors.initials: D
authors.lastname: Sharif
authors.affiliation: Technion - Israel Institute of Technology, Haifa, Israel.
authors.forename: Amal
authors.initials: A
authors.lastname: Sharif-Rasslan
authors.affiliation: Department of Cardiology, Bnai Zion Medical Center, Haifa, Israel.
authors.forename: Camilia
authors.initials: C
authors.lastname: Shahla
keywords: Coronary artery disease; Dobutamine; Ischemia; Stress echocardiogrpahy; Tissue Doppler imaging