title: Meningococcal Neonatal Purulent Conjunctivitis/Sepsis and Asymptomatic Carriage ofN. meningitidisin Mother's Vagina and Both Parents' Nasopharynx.
abstract: Neonatal conjunctivitis is usually associated with vagina's infection byChlamydiasp.,N. gonorrhoeae, and/or other bacteria during delivery. Meningococcal neonatal conjunctivitis is an extremely rare disease. We report a case of neonatal meningococcal sepsis/conjunctivitis and asymptomatic carriage ofN. meningitidisfrom both parents (vagina and nasopharynx). As part of our active surveillance for meningococcal disease at the Tijuana General Hospital (TGH), Mexico, we identified a 3-day-old newborn with meningococcal conjunctivitis and sepsis. The patient had a one-day history of conjunctivitis and poor feeding. Clinical examination confirmed profuse purulent conjunctival discharge, as well as clinical signs and laboratory findings suggestive of bacteraemia. Gram stain from conjunctival exudate revealed intracellular Gram negative diplococci; we presumed the baby had gonorrheal conjunctivitis; however, serogroup Y,N. meningitidiswas isolated both from conjunctival exudate and blood. Additionally, isolation of serogroup Y,N. meningitidiswas obtained from mother's vagina and both parents' nasopharynx. The baby was treated with 7 days of IV ceftriaxone and discharged with no sequelae.
authors.affiliation: Department of Pediatrics, Hospital General de Tijuana, Tijuana, BC, Mexico.
authors.forename: Enrique
authors.identifier: 0000-0003-2466-4920
authors.initials: E
authors.lastname: Chacon-Cruz
authors.affiliation: School of Medicine, Universidad Autonoma de Baja California, CISALUD Campus, Tecate, BC, Mexico.
authors.forename: Jorge Arturo
authors.initials: JA
authors.lastname: Alvelais-Palacios
authors.affiliation: Department of Pediatrics, Hospital General de Tijuana, Tijuana, BC, Mexico.
authors.forename: Jaime Alfonso
authors.initials: JA
authors.lastname: Rodriguez-Valencia
authors.affiliation: Department of Pediatrics, Hospital General de Tijuana, Tijuana, BC, Mexico.
authors.forename: Erika Zoe
authors.initials: EZ
authors.lastname: Lopatynsky-Reyes
authors.affiliation: Department of Microbiology, Hospital General de Tijuana, Tijuana, BC, Mexico.
authors.forename: Maria Luisa
authors.initials: ML
authors.lastname: Volker-Soberanes
authors.affiliation: Department of Microbiology, Hospital General de Tijuana, Tijuana, BC, Mexico.
authors.forename: Rosa Maria
authors.initials: RM
authors.lastname: Rivas-Landeros