title: Transcatheter Mitral Valve Interventions: Current Therapies and Future Directions.
abstract: Transcatheter interventions for the treatment of aortic valve stenosis have become commonplace since the advent of transcatheter aortic valve implantation. However, transcatheter mitral valve therapies have lagged in development due to the complexity of mitral valve anatomy. Transcatheter edge-to-edge leaflet repair using the MitraClip device provides an option for the treatment of severe primary mitral valve regurgitation in high or prohibitive surgical risk patients, and multiple novel approaches are evolving to replace or repair the mitral valve. Devices for the treatment of calcific mitral stenosis, primary mitral regurgitation, and functional mitral regurgitation have been developed and are currently either being evaluated in clinical trials or are in earlier stages of preclinical development. We are optimistic that our armamentarium will soon expand to include a myriad of transcatheter interventions for mitral valve disease.
authors.affiliation: Department of Medicine, Cardiology Division, Massachusetts General Hospital, 55 Fruit Street, GRB 800, Boston, MA, 02114, USA.|Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA, USA.
authors.forename: Ramon A
authors.initials: RA
authors.lastname: Partida
authors.affiliation: Department of Medicine, Cardiology Division, Massachusetts General Hospital, 55 Fruit Street, GRB 800, Boston, MA, 02114, USA. selmariah@mgh.harvard.edu.|Baim Institute for Clinical Research, Boston, MA, USA. selmariah@mgh.harvard.edu.
authors.forename: Sammy
authors.initials: S
authors.lastname: Elmariah
keywords: Mitral regurgitation; Mitral stenosis; Percutaneous heart valve; Transcatheter mitral repair; Transcatheter mitral replacement