title: Knee Menisci.
abstract: The menisci of the knees are semicircular fibrocartilaginous structures consisting of a hydrophilic extracellular matrix containing a network of collagen fibers, glycoproteins, and proteoglycans maintained by a cellular component. The menisci are responsible for more than 50% of load transmission across the knee and increase joint congruity thereby also aiding in fluid film lubrication of the joint. In the United Kingdom, meniscal tears are the most common form of intra-articular knee injury and one of the commonest indications for orthopedic intervention. The management of these injuries is dependent on the location within the meniscus (relative to peripheral blood supply) and the pattern of tear. Removal of meniscus is known to place the knee at increased risk of osteoarthritis; therefore repair of meniscal tears is preferable. However, a significant proportion of tears are irreparable and can only be treated by partial or even complete meniscectomy. More recent studies have shown encouraging results with meniscal replacement in this situation, though further work is required in this area.
authors.affiliation: 1 Queen Elizabeth University Hospital, Glasgow, UK.
authors.forename: James Kevin
authors.initials: JK
authors.lastname: Bryceland
authors.affiliation: 1 Queen Elizabeth University Hospital, Glasgow, UK.
authors.forename: Andrew John
authors.initials: AJ
authors.lastname: Powell
authors.affiliation: 2 Royal Alexandra Hospital, Paisley, Renfrewshire, UK.
authors.forename: Thomas
authors.initials: T
authors.lastname: Nunn
keywords: diagnosis; joint involved; knee; meniscal injury; meniscus; tissue