title: Axillary skin metastasis of renal cell carcinoma-Case report.
abstract: BACKGROUND
  Metastatic diseases are seen in approximately 25% of all cases with renal cell carcinoma and sometimes they can appear in unusual sites.
  
  
  METHODS
  We present a 35-year old patient with a painful left axillary mass which causes the functional impairment of the left arm. The axillary mass appeared 2 years after the nephrectomy performed for a left renal cell carcinoma. Numerous metastases have been identified through CT scans during the postoperative evolution of the disease for which the patient underwent adjuvant therapy with tyrosine-kinase inhibitors.
  
  
  CONCLUSIONS
  Particular to our case is not just the rare metastatic site but also the fact that the tumor appeared despite the adjuvant therapy with tyrosine-kinase inhibitors. Unfortunately, the prognosis of metastatic RCC with skin metastasis is in most cases unfavorable.
  
  
  CONCLUSIONS
  We believe that our case could add more information to subsequent measures, complete the frame of rare oncologic cases and consolidate the data published on the topic so far.
authors.affiliation: Clinical Emergency Hospital "Bagdasar-Arseni", Bucharest, Romania; University of Medicine and Pharmacy "Dr. Carol Davila", Bucharest, Romania.
authors.forename: Cristinel D
authors.initials: CD
authors.lastname: Badiu
authors.affiliation: University of Medicine and Pharmacy "Dr. Carol Davila", Bucharest, Romania. Electronic address: aungurenci1900@yahoo.com.
authors.forename: Alexandru
authors.initials: A
authors.lastname: Aungurenci
authors.affiliation: Clinical Emergency Hospital "Bagdasar-Arseni", Bucharest, Romania.
authors.forename: Cristina A
authors.initials: CA
authors.lastname: Manea
authors.affiliation: Clinical Hospital "Prof. Dr. Th. Burghele", Bucharest, Romania.
authors.forename: Radu
authors.initials: R
authors.lastname: Tomosoiu
authors.affiliation: Clinical Hospital "Prof. Dr. Th. Burghele", Bucharest, Romania.
authors.forename: Narcis
authors.initials: N
authors.lastname: Chirca
authors.affiliation: "Sf. Luca" Clinical Hospital, Bucharest, Romania.
authors.forename: Gabriela
authors.initials: G
authors.lastname: Rahnea-Nita
authors.affiliation: University of Medicine and Pharmacy "Dr. Carol Davila", Bucharest, Romania.
authors.forename: Liliana
authors.initials: L
authors.lastname: Andronache
authors.affiliation: Clinical Emergency Hospital "Bagdasar-Arseni", Bucharest, Romania; University of Medicine and Pharmacy "Dr. Carol Davila", Bucharest, Romania.
authors.forename: Valentin T
authors.initials: VT
authors.lastname: Grigorean
authors.affiliation: University of Medicine and Pharmacy "Dr. Carol Davila", Bucharest, Romania; University Emergency Central Military Hospital "Dr. Carol Davila", Bucharest, Romania.
authors.forename: Victor L
authors.initials: VL
authors.lastname: Madan
keywords: Axillary metastasis; Kinase inhibitors; Radical nephrectomy; Renal cell carcinoma