title: Novel avian leukosis viruses from domestic chicken breeds in mainland China.
abstract: Two novel avian leukosis viruses (ALVs) were isolated from 1380 whole blood samples taken from domestic chicken breeds in China. The two ALVs were uniquely different from the env (Envelope) genes of ALV A-J and carried an LTR (long terminal repeat) cluster from ALV-E. Large scale sequence analysis further showed that these ALVs (with different env and LTRs) were recently endemic in domestic chicken breeds in both China and Japan. The emergence of these novel ALVs is challenging the current ALV eradication program, and as such novel ALVs should be monitored in a timely and careful manner to stop their transmission and further recombination in the future.
authors.affiliation: Ministry of Education Key Laboratory for Avian Preventive Medicine, and Key Laboratory of Jiangsu Preventive Veterinary Medicine, Yangzhou University, 12 Wenhui East Rd, Yangzhou, 225009, Jiangsu, People's Republic of China.|Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou, Jiangsu, People's Republic of China.
authors.forename: Hongxia
authors.initials: H
authors.lastname: Shao
authors.affiliation: Ministry of Education Key Laboratory for Avian Preventive Medicine, and Key Laboratory of Jiangsu Preventive Veterinary Medicine, Yangzhou University, 12 Wenhui East Rd, Yangzhou, 225009, Jiangsu, People's Republic of China.|Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou, Jiangsu, People's Republic of China.
authors.forename: Lin
authors.initials: L
authors.lastname: Wang
authors.affiliation: Ministry of Education Key Laboratory for Avian Preventive Medicine, and Key Laboratory of Jiangsu Preventive Veterinary Medicine, Yangzhou University, 12 Wenhui East Rd, Yangzhou, 225009, Jiangsu, People's Republic of China.|Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou, Jiangsu, People's Republic of China.
authors.forename: Jianjun
authors.initials: J
authors.lastname: Sang
authors.affiliation: Ministry of Education Key Laboratory for Avian Preventive Medicine, and Key Laboratory of Jiangsu Preventive Veterinary Medicine, Yangzhou University, 12 Wenhui East Rd, Yangzhou, 225009, Jiangsu, People's Republic of China.|Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou, Jiangsu, People's Republic of China.
authors.forename: Tuofan
authors.initials: T
authors.lastname: Li
authors.affiliation: Jiangsu Lihua Animal Husbandry Stock co. LTD, Changzhou, Jiangsu, People's Republic of China.
authors.forename: Yuelong
authors.initials: Y
authors.lastname: Liu
authors.affiliation: Ministry of Education Key Laboratory for Avian Preventive Medicine, and Key Laboratory of Jiangsu Preventive Veterinary Medicine, Yangzhou University, 12 Wenhui East Rd, Yangzhou, 225009, Jiangsu, People's Republic of China.|Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou, Jiangsu, People's Republic of China.
authors.forename: Zhimin
authors.initials: Z
authors.lastname: Wan
authors.affiliation: Ministry of Education Key Laboratory for Avian Preventive Medicine, and Key Laboratory of Jiangsu Preventive Veterinary Medicine, Yangzhou University, 12 Wenhui East Rd, Yangzhou, 225009, Jiangsu, People's Republic of China.|Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou, Jiangsu, People's Republic of China.
authors.forename: Kun
authors.initials: K
authors.lastname: Qian
authors.affiliation: Ministry of Education Key Laboratory for Avian Preventive Medicine, and Key Laboratory of Jiangsu Preventive Veterinary Medicine, Yangzhou University, 12 Wenhui East Rd, Yangzhou, 225009, Jiangsu, People's Republic of China. aijian@yzu.edu.cn.|Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou, Jiangsu, People's Republic of China. aijian@yzu.edu.cn.
authors.forename: Aijian
authors.initials: A
authors.lastname: Qin
authors.affiliation: Ministry of Education Key Laboratory for Avian Preventive Medicine, and Key Laboratory of Jiangsu Preventive Veterinary Medicine, Yangzhou University, 12 Wenhui East Rd, Yangzhou, 225009, Jiangsu, People's Republic of China. jqye@yzu.edu.cn.|Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou, Jiangsu, People's Republic of China. jqye@yzu.edu.cn.
authors.forename: Jianqiang
authors.initials: J
authors.lastname: Ye
mesh_terms: D000818:Animals; D000829:Animals, Domestic / Q000821:virology; D001353:Avian Leukosis / Q000821:virology*; D001354:Avian Leukosis Virus / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification; D002645:Chickens / Q000821:virology; D002681:China; D010802:Phylogeny; D011201:Poultry Diseases / Q000821:virology*; D020079:Terminal Repeat Sequences; D014759:Viral Envelope Proteins / Q000235:genetics*
chemical_list: D014759:Viral Envelope Proteins
keywords: China; Domestic chicken breeds; Novel avian leukosis virus