title: MIP-Based Sensors: Promising New Tools for Cancer Biomarker Determination.
abstract: Detecting cancer disease at an early stage is one of the most important issues for increasing the survival rate of patients. Cancer biomarker detection helps to provide a diagnosis before the disease becomes incurable in later stages. Biomarkers can also be used to evaluate the progression of therapies and surgery treatments. In recent years, molecularly imprinted polymer (MIP) based sensors have been intensely investigated as promising analytical devices in several fields, including clinical analysis, offering desired portability, fast response, specificity, and low cost. The aim of this review is to provide readers with an overview on recent important achievements in MIP-based sensors coupled to various transducers (e.g., electrochemical, optical, and piezoelectric) for the determination of cancer biomarkers by selected publications from 2012 to 2016.
authors.affiliation: Department of Chemistry "Ugo Schiff", University of Florence, Via della Lastruccia 3, Sesto Fiorentino 50019, Italy. giulia.selvolini@unifi.it.
authors.forename: Giulia
authors.initials: G
authors.lastname: Selvolini
authors.affiliation: Department of Chemistry "Ugo Schiff", University of Florence, Via della Lastruccia 3, Sesto Fiorentino 50019, Italy. giovanna.marrazza@unifi.it.
authors.forename: Giovanna
authors.initials: G
authors.lastname: Marrazza
mesh_terms: D006801:Humans; D054802:Molecular Imprinting; D011108:Polymers; D014159:Transducers
chemical_list: D011108:Polymers
keywords: MIPs; biomarker; cancer; molecularly imprinted polymer; sensor; tumor