title: Hypochlorous acid gel technology-Its impact on postprocedure treatment and scar prevention.
abstract: BACKGROUND
  A pre-and postprocedure regime aimed at prevention of infection, reduction of inflammation and risk of scarring, is to enable optimal outcomes.
  
  
  OBJECTIVE
  The role of a hypochlorous acid containing spray and translucent scar gel formulation that combines modified silicon oil with hypochlorous acid, was explored for pre- and postprocedure treatment and scar management.
  
  
  METHODS
  For this purpose a literature review was conducted to explore the value of the technology used in pre-and postprocedural regimes. A panel of dermatologists and plastic surgeons who practice in the United States discussed the summarized search results, taking into account their current clinical practice. A nominal group process for consensus was used, followed by online reviews of the manuscript.
  
  
  RESULTS
  Based on panel discussions, consensus was reached regarding clinical recommendations given for postprocedure treatment and scar management. The hypochlorous acid products are produced with electrolysis and are classified among biocidal substances. The technology has demonstrated efficacy and safety for pre-and postprocedure use. The safety of hypochlorous solution use demonstrated to be comparable to that of standard local antiseptics. Small studies demonstrated better results with the scar gel compared to silicone gel regarding the appearance of hypertrophic and keloid scars, relief of associated pruritus and pain.
  
  
  CONCLUSIONS
  A postprocedure regime using this technology, aimed at preventing infection, reducing inflammation, and promoting healing is proposed to have benefits over current regimes as it appears to be effective, safe, and well tolerated.
authors.affiliation: Gold Skin Care Center, Nashville, TN, USA.|Tennessee Clinical Research Center, Nashville, TN, USA.|Vanderbilt University School of Nursing, Nashville, TN, USA.|School of Medicine, Meharry Medical College, Nashville, TN, USA.
authors.forename: Michael H
authors.identifier: http://orcid.org/0000-0002-5183-5433
authors.initials: MH
authors.lastname: Gold
authors.affiliation: Andriessen Consultants & Radboud UMC, Nijmegen, The Netherlands.
authors.forename: Anneke
authors.identifier: http://orcid.org/0000-0001-5930-4162
authors.initials: A
authors.lastname: Andriessen
authors.affiliation: Department of Otolaryngology, Division of Facial Plastic and Reconstructive Surgery, University of Illinois, Chicago, IL, USA.
authors.forename: Steven H
authors.initials: SH
authors.lastname: Dayan
authors.affiliation: Cosmetic Laser Dermatology, San Diego, CA, USA.
authors.forename: Sabrina G
authors.initials: SG
authors.lastname: Fabi
authors.affiliation: Lorenc Aesthetic Plastic Surgery Center, New York, NY, USA.|Department of Plastic Surgery, Lenox Hill Hospital, New York, NY, USA.
authors.forename: Z Paul
authors.initials: ZP
authors.lastname: Lorenc
authors.affiliation: Faculty of Medicine, McGill University,Montreal, Canada.
authors.forename: Meagan-Helen
authors.initials: MH
authors.lastname: Henderson Berg
mesh_terms: D000336:Aerosols; D002921:Cicatrix / Q000517:prevention & control*; D062109:Dermatologic Surgical Procedures; D005782:Gels; D006801:Humans; D006997:Hypochlorous Acid / Q000627:therapeutic use*; D011182:Postoperative Care; D011183:Postoperative Complications / Q000517:prevention & control*; D019651:Plastic Surgery Procedures
chemical_list: D000336:Aerosols; D005782:Gels; D006997:Hypochlorous Acid
keywords: hypochlorous acid technology; postprocedure care; scar management