title: Anti-glomerular basement membrane: A rare cause of renal failure in children.
abstract: Anti-glomerular basement membrane (GBM) disease is a rare cause of acute renal failure and known to have bad prognosis regarding renal functions recovery and patient survival specially when diagnosed late and presents with severe renal failure that requires dialysis. We report a case of 11-year-old child with acute renal failure secondary to anti-GBM disease and associated with antineutrophil cytoplasmic antibody-positive vasculitis. He was treated with plasmapheresis, steroids, and cyclophosphamide with recovery of his kidney functions.
authors.affiliation: Department of Pediatric Nephrology, Christian Medical College, Vellore, Tamil Nadu, India.
authors.forename: Indira
authors.initials: I
authors.lastname: Agarwal
authors.affiliation: Department of Internal Medicine, Nephrology Unit, Ain Shams University, Cairo, Egypt.
authors.forename: Ahmad
authors.initials: A
authors.lastname: Al-Ghitany
mesh_terms: D058186:Acute Kidney Injury / Q000175:diagnosis / Q000276:immunology* / Q000503:physiopathology / Q000628:therapy; D019867:Anti-Glomerular Basement Membrane Disease / Q000150:complications / Q000175:diagnosis / Q000276:immunology* / Q000503:physiopathology; D056648:Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis / Q000276:immunology; D001706:Biopsy; D002648:Child; D003131:Combined Modality Therapy; D003520:Cyclophosphamide / Q000627:therapeutic use; D005455:Fluorescent Antibody Technique; D050533:Glomerular Basement Membrane / Q000276:immunology*; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D007668:Kidney / Q000187:drug effects / Q000276:immunology* / Q000503:physiopathology; D008297:Male; D008775:Methylprednisolone / Q000627:therapeutic use; D010956:Plasmapheresis; D020127:Recovery of Function; D016896:Treatment Outcome
chemical_list: D005938:Glucocorticoids; D007166:Immunosuppressive Agents; D003520:Cyclophosphamide; D008775:Methylprednisolone