title: Viscoelastic Testing in Trauma.
abstract: Traumatic-induced coagulopathy (TIC) is a complex condition which develops both as a response to trauma as well as to clinical care interventions. Accurate and timely diagnostics are necessary to enable therapy aimed at correction of TIC. Viscoelastic hemostatic assays (VHA) are increasingly recognized for their potential to diagnose TIC as well as for guidance of treatment. This narrative review focuses on the evidence of the use of VHAs to diagnose TIC, to monitor efficacy of treatment of TIC during bleeding and to prognosticate outcome. Pitfalls of the use of VHA are also discussed.
authors.affiliation: Trauma Unit, Department of Surgery, Academic Medical Center, Amsterdam, The Netherlands.|Department of Intensive Care, Academic Medical Center, Amsterdam, The Netherlands.
authors.forename: Mathijs R
authors.initials: MR
authors.lastname: Wirtz
authors.affiliation: Department of Anaesthesiology, Academic Medical Center, Amsterdam, The Netherlands.
authors.forename: Holger M
authors.initials: HM
authors.lastname: Baumann
authors.affiliation: Laboratory for General Clinical Chemistry, Academic Medical Center, Amsterdam, The Netherlands.
authors.forename: J Henriëtte
authors.initials: JH
authors.lastname: Klinkspoor
authors.affiliation: Trauma Unit, Department of Surgery, Academic Medical Center, Amsterdam, The Netherlands.
authors.forename: J Carel
authors.initials: JC
authors.lastname: Goslings
authors.affiliation: Department of Intensive Care, Academic Medical Center, Amsterdam, The Netherlands.
authors.forename: Nicole P
authors.initials: NP
authors.lastname: Juffermans
mesh_terms: D001777:Blood Coagulation; D001778:Blood Coagulation Disorders / Q000175:diagnosis* / Q000209:etiology / Q000517:prevention & control; D001780:Blood Coagulation Tests / Q000379:methods*; D006487:Hemostasis; D006801:Humans; D008991:Monitoring, Physiologic / Q000379:methods; D013916:Thrombelastography / Q000379:methods; D014947:Wounds and Injuries / Q000097:blood / Q000150:complications*