title: Bilateral Lung Transplantation for Bleomycin-Associated Lung Injury.
abstract: This report details the successful use of bilateral lung transplantation for the management of severe postoperative bleomycin-associated lung injury. This case highlights that the extremely favorable prognosis of advanced testicular germ cell tumors after systemic chemotherapy (>90% cure rate) should not preclude lung transplant consideration in all cases, despite current guidance that considers an advanced malignancy to be a contraindication for lung transplant listing.The Oncologist2017;22:620-622.
authors.affiliation: Division of Hematology/Oncology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.
authors.forename: Vivek
authors.initials: V
authors.lastname: Narayan
authors.affiliation: Division of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.
authors.forename: Charuhas
authors.initials: C
authors.lastname: Deshpande
authors.affiliation: Cardiac Surgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.
authors.forename: Christian A
authors.initials: CA
authors.lastname: Bermudez
authors.affiliation: Penn Transplant Center, Lung Program, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
authors.forename: Jaclyn M
authors.initials: JM
authors.lastname: Golato
authors.affiliation: Division of Pulmonary, Allergy, and Critical Care, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.
authors.forename: James C
authors.initials: JC
authors.lastname: Lee
authors.affiliation: Division of Pulmonary, Allergy, and Critical Care, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.
authors.forename: Joshua
authors.initials: J
authors.lastname: Diamond
authors.affiliation: Division of Hematology/Oncology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA david.vaughn@uphs.upenn.edu.
authors.forename: David J
authors.initials: DJ
authors.lastname: Vaughn
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage / Q000009:adverse effects; D001761:Bleomycin / Q000008:administration & dosage / Q000009:adverse effects*; D002945:Cisplatin / Q000008:administration & dosage / Q000009:adverse effects; D005047:Etoposide / Q000008:administration & dosage / Q000009:adverse effects; D006801:Humans; D055370:Lung Injury / Q000139:chemically induced / Q000000981:diagnostic imaging / Q000473:pathology / Q000628:therapy*; D016040:Lung Transplantation; D008297:Male; D009373:Neoplasms, Germ Cell and Embryonal / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D013736:Testicular Neoplasms / Q000150:complications* / Q000188:drug therapy / Q000473:pathology
chemical_list: D001761:Bleomycin; D005047:Etoposide; D002945:Cisplatin