title: Current Status of Catheter-Based Treatment of Mitral Valve Regurgitation.
abstract: This review examines the current status of catheter-based repair and replacement for mitral valve disease, with a focus on native primary and secondary mitral valve regurgitation.
  
  
  
  Transcatheter mitral valve repair with the MitraClip®, with >40,000 performed procedures worldwide, has significantly advanced the field of transcatheter therapy for mitral valve regurgitation. Transcatheter mitral valve replacement remains in the early stages of development, mainly due to the complex anatomy and physiology of the mitral valve. Early feasibility studies in high-risk patients show promising procedural success, yet the adverse events require further study. Transcatheter therapies for mitral valve disease are the next endeavor for the pioneers of percutaneous structural heart disease interventions. Early results are encouraging but also show that further rigorous study is needed to determine efficacy and safety.
authors.affiliation: Valve Science Center, Minneapolis Heart Institute Abbott Northwestern Hospital, part of Allina Health, 920 East 28th Street, Suite 300, Minneapolis, MN, 55407, USA. mario.goessl@allina.com.
authors.forename: Mario
authors.initials: M
authors.lastname: Gössl
authors.affiliation: Valve Science Center, Minneapolis Heart Institute Abbott Northwestern Hospital, part of Allina Health, 920 East 28th Street, Suite 300, Minneapolis, MN, 55407, USA.
authors.forename: Robert S
authors.initials: RS
authors.lastname: Farivar
authors.affiliation: Valve Science Center, Minneapolis Heart Institute Abbott Northwestern Hospital, part of Allina Health, 920 East 28th Street, Suite 300, Minneapolis, MN, 55407, USA.
authors.forename: Richard
authors.initials: R
authors.lastname: Bae
authors.affiliation: Valve Science Center, Minneapolis Heart Institute Abbott Northwestern Hospital, part of Allina Health, 920 East 28th Street, Suite 300, Minneapolis, MN, 55407, USA.
authors.forename: Paul
authors.initials: P
authors.lastname: Sorajja
mesh_terms: D006328:Cardiac Catheterization / Q000379:methods*; D017408:Guidelines as Topic; D006350:Heart Valve Prosthesis; D019918:Heart Valve Prosthesis Implantation / Q000295:instrumentation* / Q000379:methods; D006801:Humans; D008943:Mitral Valve / Q000473:pathology*; D058386:Mitral Valve Annuloplasty / Q000295:instrumentation* / Q000379:methods; D008944:Mitral Valve Insufficiency / Q000503:physiopathology / Q000601:surgery*; D009626:Terminology as Topic; D016896:Treatment Outcome
keywords: Degenerative mitral valve regurgitation; Functional mitral valve regurgitation; Transcatheter mitral valve repair; Transcatheter mitral valve replacement