title: Hot Topics in Primary Care: Titratable Fixed-Ratio Combinations in Type 2 Diabetes Mellitus: Focus on GLP-1R Agonists Combined With Basal Insulin.
abstract: The treatment of hyperglycemia in patients without glycemic control despite metformin monotherapy is the focus of this article, with particular focus on the use of fixed-dose (FDC) and fixed-ratio combination products.
authors.affiliation: The Excelsior Springs Clinic, Excelsior Springs, MO, USA.
authors.forename: James
authors.initials: J
authors.lastname: LaSalle
authors.affiliation: Chair and Professor, Department of Pharmacotherapy, Washington State University, College of Pharmacy, Spokane, WA, USA.
authors.forename: John R
authors.initials: JR
authors.lastname: White
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003924:Diabetes Mellitus, Type 2 / Q000188:drug therapy*; D004359:Drug Therapy, Combination; D005260:Female; D006442:Glycated Hemoglobin / Q000032:analysis; D006801:Humans; D007004:Hypoglycemic Agents / Q000627:therapeutic use*; D007328:Insulin / Q000627:therapeutic use*; D008297:Male; D008687:Metformin / Q000627:therapeutic use*; D008875:Middle Aged; D018802:Patient-Centered Care / Q000592:standards*; D017410:Practice Guidelines as Topic; D011320:Primary Health Care / Q000592:standards*; D016896:Treatment Outcome; D014481:United States
chemical_list: D006442:Glycated Hemoglobin; D007004:Hypoglycemic Agents; D007328:Insulin; D008687:Metformin