title: Fresh Osteochondral Allograft Transplantation for Fractures of the Knee.
abstract: Objective The purpose of this study was to evaluate functional outcomes and allograft survivorship among patients with knee fracture who underwent fresh osteochondral allograft (OCA) transplantation as a salvage treatment option. Design Retrospective analysis of prospectively collected data. Setting Department of Orthopaedic Surgery at one hospital. Patients Fresh OCAs were implanted for osteochondral lesions after knee fracture in 24 males and 15 females with an average age of 34 years. Twenty-nine lesions (74%) were tibial plateau fractures, 6 (15%) were femoral condyle fractures, and 4 (10%) were patella fractures. Main Outcome Measurements Clinical evaluation included modified Merle d'Aubigné-Postel (18-point), International Knee Documentation Committee, and Knee Society function scores, and patient satisfaction. Failure of OCA was defined as revision OCA or conversion to total knee arthroplasty (TKA). Results Nineteen of 39 knees (49%) had further surgery. Ten knees (26%) were considered OCA failures (3 OCA revisions, 6 TKA, and 1 patellectomy). Survivorship of the OCA was 82.6% at 5 years and 69.6% at 10 years. Among the 29 knees (74%) that had the OCA still in situ, median follow-up was 6.6 years. Pain and function improved from preoperative to latest follow-up; 83% of patients reported satisfaction with OCA results. Conclusion OCA transplantation is a useful salvage treatment option for osteochondral lesions caused by knee fracture. Although the reoperation rate was high, successful outcome was associated with significant clinical improvement.
authors.affiliation: 1 Department of Orthopaedic Surgery, Federal University of São Paulo, São Paulo, Brazil.
authors.forename: Guilherme C
authors.initials: GC
authors.lastname: Gracitelli
authors.affiliation: 2 Department of Orthopaedic Surgery, Faculty of Medicine, University of São Paulo, São Paulo, Brazil.
authors.forename: Luis Eduardo Passarelli
authors.initials: LE
authors.lastname: Tirico
authors.affiliation: 3 Shiley Center for Orthopaedic Research and Education at Scripps Clinic, La Jolla, CA, USA.
authors.forename: Julie C
authors.initials: JC
authors.lastname: McCauley
authors.affiliation: 3 Shiley Center for Orthopaedic Research and Education at Scripps Clinic, La Jolla, CA, USA.
authors.forename: Pamela A
authors.initials: PA
authors.lastname: Pulido
authors.affiliation: 4 Division of Orthopaedic Surgery, Scripps Clinic, La Jolla, CA, USA.
authors.forename: William D
authors.initials: WD
authors.lastname: Bugbee
keywords: functional outcomes; knee fracture; osteochondral allograft transplant; survivorship