title: The association between red blood cell distribution width and acute pancreatitis associated lung injury in patients with acute pancreatitis.
abstract: BACKGROUND
  Red blood cell distribution width (RDW) that describes red blood cell volume heterogeneity is a common laboratory test. Our aim was to focus on the association between RDW and acute pancreatitis associated lung injury (APALI).
  
  
  METHODS
  A total of 152 acute pancreatitis (AP) patients who conformed to the criteria were included in this study. The demographic data, medical histories and laboratory measures was obtained from each patient on admission, further, the medical histories and biological data were analyzed, retrospectively.
  
  
  RESULTS
  Increased RDW at admission was observed in patients with APALI compared with the non-APALI groups. Our results exhibited that RDW was an independent risk factor for APALI after adjusting leukocyte, neutrophil percentage, random blood glucose (RBG), total bilirubin (TB) and total bile acid (TBA) (Crude model) (OR=2.671;CI 95% 1.145-6.230; P=0.023), further adjustment based on Crude model for sex and age did not attenuate the significantly high risk of APALI in patients with AP, RWD still remained a roles as an independent risk factor for APALI (OR=2.653;CI95 % 1.123-6.138; P=0.026).
  
  
  CONCLUSIONS
  Our study demonstrate that RDW at admission is associated with APALI and should be considered as an underlying risk factor of APALI.
authors.affiliation: Laboratory Medicine Diagnostic Centre, The First Affiliated Hospital, Xin Jiang Medical University, Xinjiang Urumqi, China.
authors.forename: You-Fan
authors.initials: YF
authors.lastname: Peng
authors.affiliation: Laboratory Medicine Diagnostic Centre, The First Affiliated Hospital, Xin Jiang Medical University, Xinjiang Urumqi, China.
authors.forename: Zhao-Xia
authors.initials: ZX
authors.lastname: Zhang
authors.affiliation: Hemopathy Research Center, The First Affiliated Hospital, Xin Jiang Medical University, Xinjiang Urumqi, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Cao
authors.affiliation: Laboratory Medicine Diagnostic Centre, The First Affiliated Hospital, Xin Jiang Medical University, Xinjiang Urumqi, China.
authors.forename: Cun-Ren
authors.initials: CR
authors.lastname: Meng
authors.affiliation: Department of Gastroenterology, The First Affiliated Hospital of Xinjiang Medical University, Xinjiang Urumqi, China.
authors.forename: Shen-Sheng
authors.initials: SS
authors.lastname: Xu
authors.affiliation: Laboratory Medicine Diagnostic Centre, The First Affiliated Hospital, Xin Jiang Medical University, No.1-137, Liyushan Road, Xin'shi Region, Urumqi. XinJiang, China, 830011, Phone:15022960879, Telephone:0991-4361446.
authors.forename: Qiong
authors.initials: Q
authors.lastname: Zhang
keywords: Acute pancreatitis; Acute pancreatitis associated lung injury; Red blood cell distribution width