title: Specific and relative detection of urinary microRNA signatures in bladder cancer for point-of-care diagnostics.
abstract: We present a dual-isothermal cascade strategy assisted by a lateral flow peptide nucleic acid biosensor for point-of-care detection of urinary microRNAs without a temperature protocol and complex instruments. The proposed assay is expected to be of great promise for bladder cancer diagnosis and point-of-care diagnostics.
authors.affiliation: Beijing Advanced Innovation Center for Food Nutrition and Human Health, College of Food Science & Nutritional Engineering, China Agricultural University, Beijing 100083, China. xuwentao@cau.edu.cn.
authors.forename: Nan
authors.initials: N
authors.lastname: Cheng
authors.forename: Yuancong
authors.initials: Y
authors.lastname: Xu
authors.forename: Yunbo
authors.initials: Y
authors.lastname: Luo
authors.forename: Liye
authors.initials: L
authors.lastname: Zhu
authors.forename: Yitong
authors.initials: Y
authors.lastname: Zhang
authors.forename: Kunlun
authors.initials: K
authors.lastname: Huang
authors.forename: Wentao
authors.initials: W
authors.lastname: Xu
mesh_terms: D015374:Biosensing Techniques; D006801:Humans; D035683:MicroRNAs / Q000652:urine*; D021141:Nucleic Acid Amplification Techniques; D019095:Point-of-Care Systems; D001749:Urinary Bladder Neoplasms / Q000175:diagnosis* / Q000652:urine*
chemical_list: D035683:MicroRNAs