title: Csp-Csp3Bond Formation via Iron(III)-Promoted Hydroalkynylation of Unactivated Alkenes.
abstract: An iron(III)-promoted hydroalkynylation of unactivated alkenes toward Csp-Csp3bond formation has been developed. Various alkenes, including mono-, di-, and trisubstituted alkenes, could all smoothly convert to structural diversified alkynes in this chemoselective protocol. Additionally, the scalability was unraveled and the further divergent transformations of products were conducted to demonstrate the synthetic utility.
authors.affiliation: Institute of Drug Discovery and Design, College of Pharmaceutical Sciences, Zhejiang University , 866 Yuhangtang Road, Hangzhou 310058, Zhejiang, China.
authors.forename: Yangyong
authors.initials: Y
authors.lastname: Shen
authors.affiliation: Institute of Drug Discovery and Design, College of Pharmaceutical Sciences, Zhejiang University , 866 Yuhangtang Road, Hangzhou 310058, Zhejiang, China.
authors.forename: Bo
authors.initials: B
authors.lastname: Huang
authors.affiliation: Institute of Drug Discovery and Design, College of Pharmaceutical Sciences, Zhejiang University , 866 Yuhangtang Road, Hangzhou 310058, Zhejiang, China.
authors.forename: Jing
authors.initials: J
authors.lastname: Zheng
authors.affiliation: Institute of Drug Discovery and Design, College of Pharmaceutical Sciences, Zhejiang University , 866 Yuhangtang Road, Hangzhou 310058, Zhejiang, China.
authors.forename: Chen
authors.initials: C
authors.lastname: Lin
authors.affiliation: State Key Laboratory of Plant Physiology and Biochemistry, College of Life Sciences, Zhejiang University , Hangzhou 310058, Zhejiang, China.
authors.forename: Yu
authors.initials: Y
authors.lastname: Liu
authors.affiliation: Institute of Drug Discovery and Design, College of Pharmaceutical Sciences, Zhejiang University , 866 Yuhangtang Road, Hangzhou 310058, Zhejiang, China.
authors.forename: Sunliang
authors.identifier: 0000-0001-9407-5190
authors.initials: S
authors.lastname: Cui