title: A Waterborne Outbreak of Shigella sonnei with Resistance to Azithromycin and Third-Generation Cephalosporins in China in 2015.
abstract: Here, we report for the first time a waterborne outbreak ofShigella sonneiin China in 2015. Eleven multidrug-resistant (MDR)S. sonneiisolates were recovered, showing high resistance to azithromycin and third-generation cephalosporins in particular, due to anmph(A)- andblaCTX-M-14-harboring IncB/O/K/Z group transmissible plasmid of 104,285 kb in size. Our study highlights the potential prevalence of the MDR outbreak ofS. sonneiin China and its further dissemination worldwide with the development of globalization.
authors.affiliation: Institute of Disease Control and Prevention, Academy of Military Medical Sciences, Beijing, China.|Navy's Center for Disease Control and Prevention, Beijing, China.
authors.forename: Qiuxia
authors.initials: Q
authors.lastname: Ma
authors.affiliation: Shanghai Municipal Center for Disease Control & Prevention, Shanghai, China.
authors.forename: Xuebin
authors.initials: X
authors.lastname: Xu
authors.affiliation: Yulin Center for Disease Control & Prevention, Guangxi, China.
authors.forename: Ming
authors.initials: M
authors.lastname: Luo
authors.affiliation: Institute of Disease Control and Prevention, Academy of Military Medical Sciences, Beijing, China.
authors.forename: Jian
authors.initials: J
authors.lastname: Wang
authors.affiliation: Institute of Disease Control and Prevention, Academy of Military Medical Sciences, Beijing, China.
authors.forename: Chaojie
authors.initials: C
authors.lastname: Yang
authors.affiliation: Institute of Disease Control and Prevention, Academy of Military Medical Sciences, Beijing, China.
authors.forename: Xiaofeng
authors.initials: X
authors.lastname: Hu
authors.affiliation: Institute of Disease Control and Prevention, Academy of Military Medical Sciences, Beijing, China.
authors.forename: Beibei
authors.initials: B
authors.lastname: Liang
authors.affiliation: Institute of Disease Control and Prevention, Academy of Military Medical Sciences, Beijing, China.
authors.forename: Fuli
authors.initials: F
authors.lastname: Wu
authors.affiliation: Institute of Disease Control and Prevention, Academy of Military Medical Sciences, Beijing, China.
authors.forename: Xiaoxia
authors.initials: X
authors.lastname: Yang
authors.affiliation: Institute of Disease Control and Prevention, Academy of Military Medical Sciences, Beijing, China.
authors.forename: Jinyan
authors.initials: J
authors.lastname: Wang
authors.affiliation: Institute of Disease Control and Prevention, Academy of Military Medical Sciences, Beijing, China.
authors.forename: Hongbo
authors.initials: H
authors.lastname: Liu
authors.affiliation: Yulin Center for Disease Control & Prevention, Guangxi, China.
authors.forename: Wen
authors.initials: W
authors.lastname: Li
authors.affiliation: Bobai Center for Disease Control & Prevention, Yulin, Guangxi, China.
authors.forename: Yu
authors.initials: Y
authors.lastname: Zhong
authors.affiliation: Institute of Disease Control and Prevention, Academy of Military Medical Sciences, Beijing, China.
authors.forename: Peng
authors.initials: P
authors.lastname: Li
authors.affiliation: Institute of Disease Control and Prevention, Academy of Military Medical Sciences, Beijing, China.
authors.forename: Jing
authors.initials: J
authors.lastname: Xie
authors.affiliation: Institute of Disease Control and Prevention, Academy of Military Medical Sciences, Beijing, China.
authors.forename: Leili
authors.initials: L
authors.lastname: Jia
authors.affiliation: Institute of Disease Control and Prevention, Academy of Military Medical Sciences, Beijing, China.
authors.forename: Ligui
authors.initials: L
authors.lastname: Wang
authors.affiliation: Institute of Disease Control and Prevention, Academy of Military Medical Sciences, Beijing, China.
authors.forename: Rongzhang
authors.initials: R
authors.lastname: Hao
authors.affiliation: Institute of Disease Control and Prevention, Academy of Military Medical Sciences, Beijing, China.
authors.forename: Xinying
authors.initials: X
authors.lastname: Du
authors.affiliation: Institute of Disease Control and Prevention, Academy of Military Medical Sciences, Beijing, China qiushf0613@hotmail.com hongbinsong@263.net sunys1964@hotmail.com.
authors.forename: Shaofu
authors.initials: S
authors.lastname: Qiu
authors.affiliation: Institute of Disease Control and Prevention, Academy of Military Medical Sciences, Beijing, China qiushf0613@hotmail.com hongbinsong@263.net sunys1964@hotmail.com.
authors.forename: Hongbin
authors.initials: H
authors.lastname: Song
authors.affiliation: Institute of Disease Control and Prevention, Academy of Military Medical Sciences, Beijing, China qiushf0613@hotmail.com hongbinsong@263.net sunys1964@hotmail.com.
authors.forename: Yansong
authors.initials: Y
authors.lastname: Sun
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology; D017963:Azithromycin / Q000494:pharmacology*; D002511:Cephalosporins / Q000494:pharmacology*; D002681:China; D024901:Drug Resistance, Multiple, Bacterial / Q000235:genetics; D008826:Microbial Sensitivity Tests; D010957:Plasmids / Q000235:genetics; D012764:Shigella sonnei / Q000187:drug effects* / Q000235:genetics
chemical_list: D000900:Anti-Bacterial Agents; D002511:Cephalosporins; D017963:Azithromycin
keywords: Shigella sonnei; multidrug resistance; outbreak; waterborne