title: Amplified selectivity in cognitive processing implements the neural gain model of norepinephrine function.
abstract: Previous work has suggested that an interaction between local selective (e.g., glutamatergic) excitation and global gain modulation (via norepinephrine) amplifies selectivity in information processing. Mather et al. extend this existing theory by suggesting that localized gain modulation may further mediate this effect - an interesting prospect that invites new theoretical and experimental work.
authors.affiliation: Wellcome Trust Centre for Neuroimaging,University College London,London WC1N 3BG,United Kingdome.eldar@ucl.ac.uksites.google.com/site/eldareran/.
authors.forename: Eran
authors.initials: E
authors.lastname: Eldar
authors.affiliation: Princeton Neuroscience Institute,Princeton University,Princeton,NJ 08544jdc@princeton.eduwww.csbmb.princeton.edu/ncc/yael@princeton.eduwww.princeton.edu/~nivlab/.
authors.forename: Jonathan D
authors.initials: JD
authors.lastname: Cohen
authors.affiliation: Princeton Neuroscience Institute,Princeton University,Princeton,NJ 08544jdc@princeton.eduwww.csbmb.princeton.edu/ncc/yael@princeton.eduwww.princeton.edu/~nivlab/.
authors.forename: Yael
authors.initials: Y
authors.lastname: Niv
mesh_terms: D003071:Cognition / Q000502:physiology*; D006801:Humans; D008962:Models, Theoretical; D009638:Norepinephrine / Q000502:physiology*
chemical_list: D009638:Norepinephrine