title: para-Selective C-H Borylation of (Hetero)Arenes by Cooperative Iridium/Aluminum Catalysis.
abstract: para-Selective C-H borylation of benzamides and pyridines has been achieved by cooperative iridium/aluminum catalysis. A combination of iridium catalysts commonly employed for arene C-H borylation and bulky aluminum-based Lewis acid catalysts provides an unprecedented strategy for controlling the regioselectivity of C-H borylation to give variously substituted (hetero)arylboronates, which are versatile synthetic intermediates for complex multi-substituted aromatic compounds.
authors.affiliation: Department of Material Chemistry, Graduate School of Engineering, Kyoto University, Katsura, Nishikyo-ku, Kyoto, 615-8510, Japan.
authors.forename: Lichen
authors.initials: L
authors.lastname: Yang
authors.affiliation: Department of Material Chemistry, Graduate School of Engineering, Kyoto University, Katsura, Nishikyo-ku, Kyoto, 615-8510, Japan.
authors.forename: Kazuhiko
authors.initials: K
authors.lastname: Semba
authors.affiliation: Department of Material Chemistry, Graduate School of Engineering, Kyoto University, Katsura, Nishikyo-ku, Kyoto, 615-8510, Japan.
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Nakao
keywords: C-H activation; Lewis acids; boronate esters; iridium; regioselectivity