title: Data on chemical activation of Wnt/β-catenin during axolotl limb regeneration.
abstract: Limb amputation in axolotls was performed to obtain data demonstrating that a chemical agonist of Wnt (int-related protein)/β-catenin signalling can have a role in axolotl limb regeneration (Wischin et al., 2017) [1]. The data revealed that active β-catenin protein was present during limb regeneration in some Leydig cells in the epithelium; after the chemical treatment, it was observed in more Leydig cells. In addition, the chemical agonist of Wnt generated distinct limb malformation.
authors.affiliation: Departamento de Medicina Genómica y Toxicología Ambiental, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, Mexico DF 04510, Mexico.
authors.forename: Sabina
authors.initials: S
authors.lastname: Wischin
authors.affiliation: Departamento de Bioquímica, Facultad de Medicina, Universidad Nacional Autónoma de México, Ciudad Universitaria,, Mexico DF 04510, Mexico.
authors.forename: Cristina
authors.initials: C
authors.lastname: Castañeda-Patlán
authors.affiliation: Departamento de Bioquímica, Facultad de Medicina, Universidad Nacional Autónoma de México, Ciudad Universitaria,, Mexico DF 04510, Mexico.
authors.forename: Martha
authors.initials: M
authors.lastname: Robles-Flores
authors.affiliation: Departamento de Medicina Genómica y Toxicología Ambiental, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, Mexico DF 04510, Mexico.
authors.forename: Jesús
authors.initials: J
authors.lastname: Chimal-Monroy
keywords: Limb regeneration; Wnt signaling