title: Changes in the demographics of intravenous drug users with mycotic common femoral artery pseudoaneurysm as a consequence of self-injection does not influence outcome following emergency ligation.
abstract: Objectives The reported annual incidence of mycotic pseudoaneurysm of the common femoral artery in intravenous drug users has been estimated at 0.03%. Over the past 5 years in Scotland, the proportion of people receiving specialist attention for heroin use over the age of 40 years has increased from 15 to 22%. Although routinely managed with arterial ligation (without reconstruction), some series have reported rates of major limb amputation of up to 10%. We sought to define whether this management strategy was still acceptable in an older population. Methods Retrospective review of patients presenting to a tertiary vascular service with mycotic pseudoaneurysm of the common femoral artery due to arterial injection by intravenous drug users between October 2010 and March 2016. Variables of interest included patient demographics and requirement for major amputation. Results There were 55 patients identified. The annual incidence of mycotic pseudoaneurysm of the common femoral artery in intravenous drug users was 2.1%. It was more common in men (3:1) and the mean age at presentation was 41 years (standard deviation ± 8 years). Three patients underwent major limb amputation during the index admission for severe limb ischaemia (two transfemoral amputations; one hip-disarticulation). Following discharge two patients were readmitted (134 and 200 days, respectively, following primary ligation) for major limb amputation due to of critical limb ischaemia. Conclusions Despite the increasing age of intravenous drug users presenting with mycotic pseudoaneurysm of the common femoral artery primary ligation of pseudoaneurysm would seem to remain an appropriate therapeutic intervention.
authors.affiliation: 1 Department of Vascular Surgery, Queen Elizabeth University Hospital, UK.
authors.forename: Richard P
authors.initials: RP
authors.lastname: Stevenson
authors.affiliation: 2 Department of Vascular Surgery, Raigmore Hospital, UK.
authors.forename: Catriona
authors.initials: C
authors.lastname: Semple
authors.affiliation: 1 Department of Vascular Surgery, Queen Elizabeth University Hospital, UK.
authors.forename: Keith
authors.initials: K
authors.lastname: Hussey
authors.affiliation: 1 Department of Vascular Surgery, Queen Elizabeth University Hospital, UK.
authors.forename: Josh
authors.initials: J
authors.lastname: McGovern
authors.affiliation: 1 Department of Vascular Surgery, Queen Elizabeth University Hospital, UK.
authors.forename: Wesley P
authors.initials: WP
authors.lastname: Stuart
authors.affiliation: 1 Department of Vascular Surgery, Queen Elizabeth University Hospital, UK.
authors.forename: David B
authors.initials: DB
authors.lastname: Kingsmore
mesh_terms: D000328:Adult; D000367:Age Factors; D000671:Amputation, Surgical; D017541:Aneurysm, False / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000382:microbiology / Q000601:surgery*; D000785:Aneurysm, Infected / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000382:microbiology / Q000601:surgery*; D018572:Disease-Free Survival; D055030:Drug Users; D004630:Emergencies; D005260:Female; D005263:Femoral Artery / Q000000981:diagnostic imaging / Q000382:microbiology / Q000601:surgery*; D006801:Humans; D007269:Injections, Intra-Arterial; D007275:Injections, Intravenous; D008026:Ligation; D023821:Limb Salvage; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012307:Risk Factors; D012606:Scotland; D015819:Substance Abuse, Intravenous / Q000175:diagnosis / Q000453:epidemiology*; D013997:Time Factors; D016896:Treatment Outcome; D014656:Vascular Surgical Procedures / Q000009:adverse effects
keywords: Vascular; demographics; femoral; intravenous drug users; pseudoaneurysm