title: PainVision® Apparatus for Assessment of Efficacy of Pulsed Radiofrequency Combined with Pharmacological Therapy in the Treatment of Postherpetic Neuralgia and Correlations with Measurements.
abstract: Objective. PainVision device was a developed application for the evaluation of pain intensity. The objective was to assess the efficacy and safety of pulsed radiofrequency (PRF) combined with pharmacological therapy in the treatment of postherpetic neuralgia (PHN). We also discussed the correlation of the measurements.Method. Forty patients with PHN were randomized for treatment with PRF combined with pharmacological therapy (PRF group,n= 20) or pharmacological therapy (control group,n= 20) at postoperative 48 hours. The efficacy measure was pain degree (PD) that was assessed by PainVision and visual analog scale (VAS), short form Mcgill pain questionnaire (SF-Mcgill), and numeric rate scale sleep interference score (NRSSIS). Correlations between PD, VAS, SF-Mcgill, and NRSSIS were determined.Results. The PD for persistent pain (PP) and breakthrough pain (BTP) at postoperative 48 hours assessed by PainVision were significantly lower in PRF group than in control group (PD-PP,P< 0.01; PD-BTP,P< 0.01). PD and VAS were highly correlated for both persistent pain (r= 0.453,ρ= 0.008) and breakthrough pain (r= 0.64,ρ= 0.001).Conclusion. PRF was well tolerated and superior to isolated pharmacological therapy in the treatment of PHN. PainVision device showed great value in the evaluation of pain intensity and PD had an excellent correlation with VAS and SF-Mcgill.
authors.affiliation: Department of Pain Management, Jinan Central Hospital Affiliated to Shandong University, Jinan, Shandong, China; Department of Anesthesia, Zhangqiu District Chinese Medical Hospital, Jinan, Shandong, China.
authors.forename: Dong
authors.identifier: 0000-0002-9091-7618
authors.initials: D
authors.lastname: Wang
authors.affiliation: Department of Anesthesia, Zhangqiu District Chinese Medical Hospital, Jinan, Shandong, China.
authors.forename: Kai
authors.initials: K
authors.lastname: Zhang
authors.affiliation: Department of Neurosurgery, The Sixth People's Hospital of Jinan, Shandong, China.
authors.forename: ShaoLong
authors.initials: S
authors.lastname: Han
authors.affiliation: Department of Pain Management, Jinan Central Hospital Affiliated to Shandong University, Jinan, Shandong, China.
authors.forename: LingZhi
authors.identifier: 0000-0001-8206-3694
authors.initials: L
authors.lastname: Yu
mesh_terms: D000368:Aged; D003038:Cobamides / Q000008:administration & dosage; D004008:Diclofenac / Q000008:administration & dosage; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D051474:Neuralgia, Postherpetic / Q000188:drug therapy* / Q000503:physiopathology / Q000532:radiotherapy*; D010147:Pain Measurement / Q000187:drug effects / Q000528:radiation effects; D000069583:Pregabalin / Q000008:administration & dosage; D061208:Pulsed Radiofrequency Treatment; D011795:Surveys and Questionnaires
chemical_list: D003038:Cobamides; D004008:Diclofenac; D000069583:Pregabalin; C000913:cobamamide