title: Long-term outcome of an intra-articular allograft technique for treatment of spontaneous cranial cruciate ligament rupture in the dog.
abstract: OBJECTIVE
  To determine the 12-month outcome in dogs with spontaneous cranial cruciate ligament (CCL) rupture after repair with an intra-articular decellularized allograft.
  
  
  METHODS
  Prospective pilot case series.
  
  
  METHODS
  Ten client-owned dogs with unilateral CCL rupture.
  
  
  METHODS
  An intra-articular, decellularized, deep digital flexor tendon allograft was secured in the stifle with a femoral cross pin and tibial spiked washers and screws. An interference screw was placed in the tibial tunnel. Dogs were evaluated with an owner questionnaire, radiographs, and force platform gait analysis before and 2, 6, and 12 months after surgery.
  
  
  RESULTS
  Owners reported improvement in level of pain and mobility throughout the study, especially over the first 6 months. Peak vertical force and vertical impulse improved across all time points. Ground reaction force asymmetry index for peak vertical force and vertical impulse at 12 months showed 3 dogs within a normal index (<6%), 4 dogs as nonvisibly lame (6-20%), and 3 dogs as visibly lame (≥20%). For most dogs, osteoarthritis scoring did not change over the 12-month period and some femoral-tibial translation was detected on standing horizontal beam radiographs.
  
  
  CONCLUSIONS
  Intra-articular repair using a decellularized allograft can provide functional clinical outcomes in dogs with CCL disease. A better understanding of long-term engraftment after this procedure is needed.
authors.affiliation: Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Tennessee, Knoxville, Tennessee.
authors.forename: Jeffery J
authors.initials: JJ
authors.lastname: Biskup
authors.affiliation: Department of Veterinary Clinical Sciences and Clinical Investigation Center, University of Minnesota, St. Paul, Minnesota.
authors.forename: Daniel G
authors.initials: DG
authors.lastname: Balogh
authors.affiliation: Department of Veterinary Clinical Sciences and Clinical Investigation Center, University of Minnesota, St. Paul, Minnesota.
authors.forename: Ruth M
authors.initials: RM
authors.lastname: Scott
authors.affiliation: Department of Veterinary Clinical Sciences and Clinical Investigation Center, University of Minnesota, St. Paul, Minnesota.
authors.forename: Michael G
authors.initials: MG
authors.lastname: Conzemius
mesh_terms: D064591:Allografts; D000818:Animals; D016118:Anterior Cruciate Ligament / Q000601:surgery; D000070598:Anterior Cruciate Ligament Injuries / Q000601:surgery / Q000662:veterinary*; D001863:Bone Screws / Q000662:veterinary; D004283:Dog Diseases / Q000601:surgery*; D004285:Dogs; D005269:Femur / Q000601:surgery; D010003:Osteoarthritis / Q000601:surgery / Q000662:veterinary*; D011859:Radiography; D012421:Rupture / Q000662:veterinary; D013264:Stifle / Q000601:surgery; D013977:Tibia / Q000601:surgery; D016896:Treatment Outcome