title: Sclerotherapy for Orbital Lymphangioma - Case Series and Literature Review.
abstract: Orbital lymphangioma is a lymphatic system lesion that commonly presents in childhood. Management of these lesions is complex. Sclerotherapy is a therapy used to treat and shrink lesions prior to or as an alternative to surgery. We present three cases of orbital lymphangioma that were treated with sclerotherapy. Case 1: A 6-month-old boy was presented in 2010 with right ptosis and proptosis. Magnetic resonance imaging (MRI) identified a lesion involving the right orbit and face. Case 2: A 3-year-old girl was presented in 2011 with intermittent right periorbital swelling and medial canthal bleeding. MRI identified a soft-tissue lesion in the right orbit, extending into the face. Case 3: A 3-year-old girl was presented in 2012 with vomiting, and painful right proptosis. MRI identified an intra-conal lesion in the right orbit with fluid filled levels. All three patients were treated with sclerotherapy (sodium tetradecylsulfate). Sclerotherapy is a promising treatment for orbital lymphangioma. Its use may prevent the need for, or minimise the amount of surgical management. Several sclerosants are now commonly used to treat these lesions.
authors.affiliation: Department of Ophthalmology, Huddersfield Royal Infirmary, Huddersfield, U.K. karnesh@doctors.org.uk.
authors.forename: Karnesh Chandrakant
authors.initials: KC
authors.lastname: Patel
authors.affiliation: Department of Ophthalmology, St. James' University Hospital, Leeds Teaching Hospitals NHS Trust, Leeds, U.K.
authors.forename: George
authors.initials: G
authors.lastname: Kalantzis
authors.affiliation: Department of Ophthalmology, St. James' University Hospital, Leeds Teaching Hospitals NHS Trust, Leeds, U.K.
authors.forename: Nabil
authors.initials: N
authors.lastname: El-Hindy
authors.affiliation: Department of Ophthalmology, St. James' University Hospital, Leeds Teaching Hospitals NHS Trust, Leeds, U.K.
authors.forename: Bernard Y
authors.initials: BY
authors.lastname: Chang
mesh_terms: D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008202:Lymphangioma / Q000000981:diagnostic imaging / Q000628:therapy*; D008279:Magnetic Resonance Imaging; D008297:Male; D009915:Orbit / Q000000981:diagnostic imaging / Q000473:pathology; D009918:Orbital Neoplasms / Q000000981:diagnostic imaging / Q000628:therapy*; D012597:Sclerosing Solutions / Q000627:therapeutic use; D015911:Sclerotherapy / Q000379:methods*; D012981:Sodium Tetradecyl Sulfate / Q000627:therapeutic use; D016896:Treatment Outcome
chemical_list: D012597:Sclerosing Solutions; D012981:Sodium Tetradecyl Sulfate
keywords: Paediatric; lymphangioma; orbital; sclerotherapy; sodium tetradecylsulfate (STS)