title: Extension to the Silyl-Tethered Radical Cyclization: Cyclohex-2-en-1-oxy Vinyl Silanes in Stereoselective Radical Addition/Cyclization Cascades.
abstract: A novel radical cascade reaction of xanthates with 1-[(vinyldimethylsilyl)oxy]cyclohex-2-enes is developed. Due to the steric and electronic differentiation of the two olefinic functions, exclusive regioselectivity and high stereoselectivity of the addition-cyclization are observed. Several methods for modification of both the silicon tether and the xanthate function are reported.
authors.affiliation: Laboratoire de Synthèse Organique, CNRS UMR 7652 Ecole Polytechnique , Palaiseau 91128 Cedex, France.
authors.forename: Andrey A
authors.initials: AA
authors.lastname: Mikhaylov
authors.affiliation: Laboratoire de Synthèse Organique, CNRS UMR 7652 Ecole Polytechnique , Palaiseau 91128 Cedex, France.
authors.forename: Samir Z
authors.identifier: 0000-0002-5456-910X
authors.initials: SZ
authors.lastname: Zard