title: The effect of acute maximal exercise on postexercise hemodynamics and central arterial stiffness in obese and normal-weight individuals.
abstract: Central arterial stiffness is associated with incident hypertension and negative cardiovascular outcomes. Obese individuals have higher central blood pressure (BP) and central arterial stiffness than their normal-weight counterparts, but it is unclear whether obesity also affects hemodynamics and central arterial stiffness after maximal exercise. We evaluated central hemodynamics and arterial stiffness during recovery from acute maximal aerobic exercise in obese and normal-weight individuals. Forty-six normal-weight and twenty-one obese individuals underwent measurements of central BP and central arterial stiffness at rest and 15 and 30 min following acute maximal exercise. Central BP and normalized augmentation index (AIx@75) were derived from radial artery applanation tonometry, and central arterial stiffness was obtained via carotid-femoral pulse wave velocity (cPWV) and corrected for central mean arterial pressure (cPWV/cMAP). Central arterial stiffness increased in obese individuals but decreased in normal-weight individuals following acute maximal exercise, after adjusting for fitness. Obese individuals also exhibited an overall higher central BP (P<0.05), with no exercise effect. The increase in heart rate was greater in obese versus normal-weight individuals following exercise (P<0.05), but there was no group differences or exercise effect for AIx@75 In conclusion, obese (but not normal-weight) individuals increased central arterial stiffness following acute maximal exercise. An assessment of arterial stiffness response to acute exercise may serve as a useful detection tool for subclinical vascular dysfunction.
authors.affiliation: Department of Kinesiology and Nutrition, University of Illinois at Chicago, Chicago, Illinois bunsawa2@uic.edu.
authors.forename: Kanokwan
authors.initials: K
authors.lastname: Bunsawat
authors.affiliation: Department of Anesthesiology, Mayo Clinic, Rochester, Minnesota.
authors.forename: Sushant M
authors.initials: SM
authors.lastname: Ranadive
authors.affiliation: Department of Preventive Medicine, Northwestern University, Chicago, Illinois.
authors.forename: Abbi D
authors.initials: AD
authors.lastname: Lane-Cordova
authors.affiliation: Department of Exercise and Health Sciences University of Massachusetts Boston, Boston, Massachusetts.
authors.forename: Huimin
authors.initials: H
authors.lastname: Yan
authors.affiliation: Department of Health and Exercise Science, Appalachian State University, Boone, North Carolina.
authors.forename: Rebecca M
authors.initials: RM
authors.lastname: Kappus
authors.affiliation: Department of Kinesiology and Nutrition, University of Illinois at Chicago, Chicago, Illinois.
authors.forename: Bo
authors.initials: B
authors.lastname: Fernhall
authors.affiliation: Department of Kinesiology and Nutrition, University of Illinois at Chicago, Chicago, Illinois.
authors.forename: Tracy
authors.initials: T
authors.lastname: Baynard
mesh_terms: D000328:Adult; D001794:Blood Pressure / Q000502:physiology*; D003430:Cross-Sectional Studies; D015444:Exercise / Q000502:physiology*; D005260:Female; D006439:Hemodynamics / Q000502:physiology; D006801:Humans; D008297:Male; D009765:Obesity / Q000503:physiopathology*; D063177:Pulse Wave Analysis; D059289:Vascular Stiffness / Q000502:physiology*; D055815:Young Adult
keywords: Arterial stiffness; blood pressure; exercise; obesity