title: Influenza in children.
abstract: OBJECTIVE
  We review the current information and evidence available on the global burden of disease in the pediatric population, clinical presentation and complications, testing, treatment, and immunization.
  
  
  RESULTS
  In addition to multiple other risk factors for influenza complications, children with neurologic and neuromuscular disorders are significantly higher risk for serious complications. In practice, there is no lower age limit for children with influenza who can be treated with oseltamivir. The quadrivalent live attenuated influenza vaccine was not recommended for use during the 2016-2017 season due to poor effectiveness.
  
  
  CONCLUSIONS
  Influenza infection causes a significant burden of disease each year in the pediatric population worldwide. Both healthy and chronically ill children can fall prey to complications either due to the virus itself or secondary bacterial infection. Children within high-risk groups should be tested and treated with neuraminidase inhibitors. Immunization against influenza is well tolerated and effective.
authors.affiliation: Division of Pediatric Emergency Medicine, Weill Cornell Medical College, New York Presbyterian Hospital, New York, New York, USA.
authors.forename: Janienne
authors.initials: J
authors.lastname: Kondrich
authors.forename: Michele
authors.initials: M
authors.lastname: Rosenthal
mesh_terms: D000998:Antiviral Agents / Q000627:therapeutic use; D002648:Child; D017281:Cost of Illness; D014943:Global Health; D006801:Humans; D007252:Influenza Vaccines; D007251:Influenza, Human / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy; D053139:Oseltamivir / Q000627:therapeutic use; D012307:Risk Factors
chemical_list: D000998:Antiviral Agents; D007252:Influenza Vaccines; D053139:Oseltamivir