title: Challenges in gluten-free diet in coeliac disease: Prague consensus.
abstract: BACKGROUND
  New treatments in coeliac disease are being vigorously pursued to either replace or facilitate the difficult-tofollow gluten-free diet.
  
  
  METHODS
  The present review intends to summarise the challenges in gluten-free diet adherence during the transitional period, as reflected in the last Prague consensus, published in 2016.
  
  
  RESULTS
  The honourable panel members recommended that dietary adherence and the consequences of nonadherence represent key components for discussion in the transitional period setting.
  
  
  CONCLUSIONS
  There are numerous difficulties in adhering to gluten withdrawal, but the transition period from adolescence to young adulthood is considered a fragile and high-risk period for intentional and unintentional gluten intake.
authors.affiliation: Department of Immunology, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
authors.forename: Gabriel
authors.identifier: http://orcid.org/0000-0002-7645-0716
authors.initials: G
authors.lastname: Samasca
authors.affiliation: B. Rappaport School of Medicine, Technion-Israel Institute of Technology, Haifa, Israel.|AESKU.KIPP Institute, Wendelsheim, Germany.
authors.forename: Aaron
authors.initials: A
authors.lastname: Lerner
authors.affiliation: Department of Immunology, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
authors.forename: Anamaria
authors.initials: A
authors.lastname: Girbovan
authors.affiliation: Department of Pediatrics II, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
authors.forename: Genel
authors.initials: G
authors.lastname: Sur
authors.affiliation: Department of Molecular Biology and Biotechnology, Babes-Bolyai University, ClujNapoca, Romania.
authors.forename: Iulia
authors.initials: I
authors.lastname: Lupan
authors.affiliation: Department of Transgenic Models of Disease, Institute of Molecular Genetics, Czech Centre for Phenogenomics, ASCR, v.v.i., BIOCEV, Vestec, Czech Republic.
authors.forename: Peter
authors.initials: P
authors.lastname: Makovicky
authors.affiliation: AESKU.KIPP Institute, Wendelsheim, Germany.
authors.forename: Torsten
authors.initials: T
authors.lastname: Matthias
authors.affiliation: Department of Gastroenterology, University of British Columbia, Vancouver, BC, Canada.
authors.forename: Hugh J
authors.initials: HJ
authors.lastname: Freeman
mesh_terms: D000293:Adolescent; D000367:Age Factors; D002446:Celiac Disease / Q000178:diet therapy*; D055050:Diet, Gluten-Free; D006801:Humans; D010349:Patient Compliance; D017410:Practice Guidelines as Topic; D055815:Young Adult
keywords: Adult; biomarkers; childhood; dietary adherence; gluten-free diet; transition