title: Ionic liquids based on imidazole for online concentration of catecholamines in capillary electrophoresis.
abstract: Potential possibilities of long-chain ionic liquids based on imidazole (1-dodecyl-3-methylimidazolium chloride and 1-cetyl-3-methylimidazolium chloride) for online sample concentration techniques (field-amplified sample stacking, head-column field-amplified sample stacking, and sweeping) of catecholamines were studied in both capillary zone electrophoresis and micellar electrokinetic chromatography. The use of a high-conductivity sample matrix in sweeping was found to significantly increase the separation efficiency of analyte up to 2 × 106theoretical plates per meter and remarkably reduce limits of detection for catecholamines up to 50 ng/mL. This approach was shown to be suitable for the determination of trace amounts of catecholamines in biological fluids.
authors.affiliation: Institute of Chemistry, Saint Petersburg State University, Saint Petersburg, Russia.
authors.forename: Elena
authors.initials: E
authors.lastname: Bessonova
authors.affiliation: Institute of Chemistry, Saint Petersburg State University, Saint Petersburg, Russia.
authors.forename: Liudmila
authors.initials: L
authors.lastname: Kartsova
authors.affiliation: Institute of Chemistry, Saint Petersburg State University, Saint Petersburg, Russia.
authors.forename: Valeria
authors.initials: V
authors.lastname: Gallyamova
mesh_terms: D002395:Catecholamines / Q000032:analysis*; D020374:Chromatography, Micellar Electrokinetic Capillary; D019075:Electrophoresis, Capillary; D007093:Imidazoles / Q000737:chemistry*; D052578:Ionic Liquids / Q000737:chemistry*
chemical_list: D002395:Catecholamines; D007093:Imidazoles; D052578:Ionic Liquids
keywords: capillary electrophoresis; catecholamines; ionic liquids; online concentration