title: [Determination of dimethyl sulfate in the air of workplace by GC-MS].
abstract: Objective:To establish a method to detect the concentrations of dimethyl sulfate in the air of workplace by GC-MS.Methods:DMS in the air of workplace adsorpted by Silicone tube, then desorped by acetone, add 1.0 ml of acetone, shake 1 min, placed after 30 min, the desorption solution qualitative and quantitative determination by gas chromatography-mass.Results:The calibration curves were liner in the range of 0.1-200.0 μg/ml. The within-run and between-run precisions were 2.6%-4.7% and 4.0%-9.0% respectively. The method detection limit is 0.1 μg/ml, the minimum detectable concentration is 0.02 mg/m(3) (in terms of sampling 4.5 L) . Add 1 ml of desorption liquid, place 30 min, the average desorption efficiency of more than 90%.Conclusion:This method has simple pretreatment, short analysis period, and optimized linear rage and limit of detection, and is suitable for the determination of DMS in workplace air.
authors.affiliation: Provincial Center for Disease Control and Prevention, Nanjing 210009, China.
authors.forename: C M
authors.initials: CM
authors.lastname: Zhou
authors.forename: B L
authors.initials: BL
authors.lastname: Zhu
authors.forename: X J
authors.initials: XJ
authors.lastname: Li
authors.forename: J
authors.initials: J
authors.lastname: Wu
authors.forename: Y M
authors.initials: YM
authors.lastname: Liu
mesh_terms: D000388:Air; D000395:Air Pollutants, Occupational / Q000032:analysis*; D002849:Chromatography, Gas / Q000379:methods*; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods*; D006801:Humans; D013463:Sulfuric Acid Esters / Q000302:isolation & purification*; D017132:Workplace
chemical_list: D000395:Air Pollutants, Occupational; D013463:Sulfuric Acid Esters; C007482:dimethyl sulfate
keywords: Air; Dimethyl sulfate; GC-MS; Workplace