title: Extended Criteria Donors in Liver Transplantation.
abstract: Mortality rates on the liver transplant waiting list are increasing. The shortage of organs has resulted in higher utilization of extended criteria donors (ECDs), with centers pushing the limits of what is acceptable for transplantation. Donor quality is more appropriately represented as a continuum of risk, and careful selection and matching of ECD grafts with recipients may lead to excellent outcomes. Although there is no precise definition for what constitutes an ECD liver, this review focuses on frequently cited characteristics, including donor age, steatosis, donation after cardiac death, and donors with increased risk of disease transmission.
authors.affiliation: Division of Gastroenterology and Hepatology, University of California, San Diego, 200 West Arbor Drive M/C 8413, San Diego, CA, USA. Electronic address: ivodkin@ucsd.edu.
authors.forename: Irine
authors.initials: I
authors.lastname: Vodkin
authors.affiliation: Division of Gastroenterology and Hepatology, University of California, San Diego, 200 West Arbor Drive M/C 8413, San Diego, CA, USA.
authors.forename: Alexander
authors.initials: A
authors.lastname: Kuo
mesh_terms: D000367:Age Factors; D006801:Humans; D016031:Liver Transplantation; D018579:Patient Selection; D014019:Tissue Donors; D009927:Tissue and Organ Procurement / Q000592:standards*; D014850:Waiting Lists
keywords: Centers for Disease Control and Prevention high-risk donors; Disease transmission; Donation after cardiac death; Extended criteria donor; Liver transplantation