title: Primary Breast Lymphoma with cutaneous involvement in a patient with Rheumatoid Arthritis - a complication of infliximab therapy?
abstract: It is well established that rheumatoid arthritis is associated with an increased risk of lymphoma. The use of tumor-necrosis factor-α inhibitors as a therapy in rheumatoid arthritis has been related to higher incidence of lymphoma arising at atypical and/or unusual locations; however, recent data shows their safety. We report the case of a 79 year-old woman with rheumatoid arthritis treated with infliximab, who presented a primary breast lymphoma with cutaneous involvement.
authors.affiliation: Centro Hospitalar e Universitário de Coimbra.
authors.forename: Carlos
authors.initials: C
authors.lastname: Costa
authors.affiliation: Centro Hospitalar Baixo Vouga.
authors.forename: Renata
authors.initials: R
authors.lastname: Aguiar
authors.affiliation: Centro Hospitalar e Universitário de Coimbra.
authors.forename: Marília
authors.initials: M
authors.lastname: Rodrigues
authors.affiliation: Centro Hospitalar e Universitário de Coimbra.
authors.forename: Pedro
authors.initials: P
authors.lastname: Carvalho
authors.affiliation: Centro Hospitalar e Universitário de Coimbra.
authors.forename: Joana
authors.initials: J
authors.lastname: Ferreira
authors.affiliation: Centro Hospitalar e Universitário de Coimbra.
authors.forename: Mariana
authors.initials: M
authors.lastname: Santiago
authors.affiliation: Centro Hospitalar e Universitário de Coimbra.
authors.forename: Luis
authors.initials: L
authors.lastname: Rito
authors.affiliation: Centro Hospitalar e Universitário de Coimbra.
authors.forename: Jorge
authors.initials: J
authors.lastname: Silva
authors.affiliation: Centro Hospitalar e Universitário de Coimbra.
authors.forename: Cátia
authors.initials: C
authors.lastname: Duarte
authors.affiliation: Centro Hospitalar e Universitário de Coimbra.
authors.forename: Jap
authors.initials: J
authors.lastname: da Silva
authors.affiliation: Centro Hospitalar e Universitário de Coimbra.
authors.forename: Armando
authors.initials: A
authors.lastname: Malcata
mesh_terms: D000368:Aged; D018501:Antirheumatic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D001172:Arthritis, Rheumatoid / Q000188:drug therapy; D001943:Breast Neoplasms / Q000139:chemically induced*; D005260:Female; D006801:Humans; D000069285:Infliximab / Q000009:adverse effects* / Q000627:therapeutic use; D008223:Lymphoma; D018442:Lymphoma, B-Cell, Marginal Zone / Q000139:chemically induced*; D009378:Neoplasms, Multiple Primary / Q000139:chemically induced*; D012878:Skin Neoplasms / Q000139:chemically induced*
chemical_list: D018501:Antirheumatic Agents; D000069285:Infliximab