title: A mitochondria-targeted fluorescent probe for imaging endogenous malondialdehyde in HeLa cells and onion tissues.
abstract: The mitochondria-targeted turn-on fluorescent probe (Mito-FMP) based on a benzoxadiazole platform was developed for detection of malondialdehyde (MDA). Mito-FMP performed with large enhancement of the optical signal (774-fold) in response to MDA in an aqueous system and has the capability of monitoring endogenous MDA in HeLa cells and onion tissues.
authors.affiliation: Institute of Fluorescent Probes for Biological Imaging, School of Chemistry and Chemical Engineering, School of Materials Science and Engineering, University of Jinan, Shandong 250022, P. R. China. weiyinglin2013@163.com.
authors.forename: Longwei
authors.identifier: http://orcid.org/0000-0002-8206-8783
authors.initials: L
authors.lastname: He
authors.affiliation: Institute of Fluorescent Probes for Biological Imaging, School of Chemistry and Chemical Engineering, School of Materials Science and Engineering, University of Jinan, Shandong 250022, P. R. China. weiyinglin2013@163.com.
authors.forename: Xueling
authors.initials: X
authors.lastname: Yang
authors.affiliation: Institute of Fluorescent Probes for Biological Imaging, School of Chemistry and Chemical Engineering, School of Materials Science and Engineering, University of Jinan, Shandong 250022, P. R. China. weiyinglin2013@163.com.
authors.forename: Kaixin
authors.initials: K
authors.lastname: Xu
authors.affiliation: Institute of Fluorescent Probes for Biological Imaging, School of Chemistry and Chemical Engineering, School of Materials Science and Engineering, University of Jinan, Shandong 250022, P. R. China. weiyinglin2013@163.com.
authors.forename: Weiying
authors.identifier: http://orcid.org/0000-0001-8080-4102
authors.initials: W
authors.lastname: Lin
mesh_terms: D005456:Fluorescent Dyes / Q000737:chemistry*; D006367:HeLa Cells; D006801:Humans; D008315:Malondialdehyde / Q000032:analysis*; D008928:Mitochondria / Q000737:chemistry*; D015394:Molecular Structure; D019697:Onions / Q000737:chemistry*; D061848:Optical Imaging; D010069:Oxadiazoles / Q000737:chemistry*
chemical_list: D005456:Fluorescent Dyes; D010069:Oxadiazoles; D008315:Malondialdehyde