title: Monitoring Cerebral Oxygenation in Neonates: An Update.
abstract: Cerebral oxygenation is not always reflected by systemic arterial oxygenation. Therefore, regional cerebral oxygen saturation (rScO2) monitoring with near-infrared spectroscopy (NIRS) is of added value in neonatal intensive care. rScO2represents oxygen supply to the brain, while cerebral fractional tissue oxygen extraction, which is the ratio between rScO2and systemic arterial oxygen saturation, reflects cerebral oxygen utilization. The balance between oxygen supply and utilization provides insight in neonatal cerebral (patho-)physiology. This review highlights the potential and limitations of cerebral oxygenation monitoring with NIRS in the neonatal intensive care unit.
authors.affiliation: Department of Neonatology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, Netherlands; Monash Newborn, Monash Medical Centre, Melbourne, VIC, Australia.
authors.forename: Laura Marie Louise
authors.initials: LM
authors.lastname: Dix
authors.affiliation: Department of Neonatology, Wilhelmina Children's Hospital, University Medical Center Utrecht , Utrecht , Netherlands.
authors.forename: Frank
authors.initials: F
authors.lastname: van Bel
authors.affiliation: Department of Neonatology, Wilhelmina Children's Hospital, University Medical Center Utrecht , Utrecht , Netherlands.
authors.forename: Petra Maria Anna
authors.initials: PM
authors.lastname: Lemmers
keywords: cerebral oxygenation; near-infrared spectroscopy; neonatal intensive care; neonatal neurology; neonates