title: Horizontal alignment of 5' -> 3' intergene distance segment tropy with respect to the gene as the conserved basis for DNA transcription.
abstract: OBJECTIVE
  To study the conserved basis for gene expression in comparative cell types at opposite ends of the cell pressuromodulation spectrum, the lymphatic endothelial cell and the blood microvascular capillary endothelial cell.
  
  
  METHODS
  The mechanism for gene expression is studied in terms of the 5' -> 3' direction paired point tropy quotients (prpTQs) and the final 5' -> 3' direction episodic sub-episode block sums split-integrated weighted average-averaged gene overexpression tropy quotient (esebssiwaagoTQ).
  
  
  RESULTS
  The final 5' -> 3'esebssiwaagoTQclassifies an lymphatic endothelial cell overexpressed gene as a supra-pressuromodulated gene (esebssiwaagoTQ≥ 0.25 < 0.75) every time and classifies a blood microvascular capillary endothelial cell overexpressed gene every time as an infra-pressuromodulated gene (esebssiwaagoTQ< 0.25) (100% sensitivity; 100% specificity).
  
  
  CONCLUSIONS
  Horizontal alignment of 5' -> 3' intergene distance segment tropywrtthe gene is the basis for DNA transcription in the pressuromodulated state.
authors.affiliation: Freelance Investigator in Translational Science & Medicine (unaffiliated), 833 Carroll Road, Charleston, WV 25314, USA.
authors.forename: Hemant
authors.initials: H
authors.lastname: Sarin
keywords: cell membrane pressuromodulation; eukaryote; genomics; infra-pressuromodulated gene; nuclear pressuromodulation; peptide; prokaryote; small hormone pressuromodulator; supra-pressuromodulated gene; virus