title: Pregnancy Outcomes Following Ulipristal Acetate Emergency Contraception Failure: A Report of Five Cases.
abstract: BACKGROUND
  The emergency contraceptive ulipristal acetate (UPA) 30 mg is increasingly used by women, but there is no published data on UPA exposure in pregnancy.
  
  
  METHODS
  Here we describe five cases of unintended pregnancies following the use of UPA for emergency contraception. Of five pregnant women exposed to UPA, one decided to terminate the pregnancy for personal reasons. Two of them experienced premature rupture of membranes and the babies were born large for gestational age (LGA). The other two women experienced gestational diabetes, and one of them also delivered a LGA baby. The blood glucose levels of the mothers were normal after delivery and at six weeks postpartum. No birth defects and no growth or developmental abnormalities for the infants were reported during 6 months follow-up.
  
  
  CONCLUSIONS
  Pregnant women inadvertently exposed to UPA should be monitored carefully, unless further data are available.
authors.affiliation: a Department of Clinical Pharmacology and Toxicology , Izmir Atatürk Research Hospital , Izmir , Turkey.
authors.forename: Zeynep
authors.initials: Z
authors.lastname: Ozturk
authors.affiliation: a Department of Clinical Pharmacology and Toxicology , Izmir Atatürk Research Hospital , Izmir , Turkey.
authors.forename: Emine
authors.initials: E
authors.lastname: Akgul
mesh_terms: D000328:Adult; D044363:Contraception, Postcoital / Q000009:adverse effects*; D003271:Contraceptive Agents, Female / Q000009:adverse effects*; D000073516:Contraceptive Effectiveness; D016640:Diabetes, Gestational / Q000209:etiology; D005260:Female; D005320:Fetal Macrosomia / Q000209:etiology; D005322:Premature Rupture of Fetal Membranes / Q000209:etiology; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D009649:Norpregnadienes / Q000009:adverse effects*; D011247:Pregnancy; D011256:Pregnancy Outcome; D049168:Pregnancy, Unplanned; D012189:Retrospective Studies
chemical_list: D003271:Contraceptive Agents, Female; D009649:Norpregnadienes; C555622:ulipristal acetate
keywords: Pregnancy; gestational diabetes mellitus; large for gestational age; premature rupture of membranes; ulipristal