title: Wheat genomics comes of age.
abstract: Advances in wheat genomics have lagged behind other major cereals (e.g., rice and maize) due to its highly repetitive and large polyploid genome. Recent technological developments in sequencing and assembly methods, however, have largely overcome these barriers. The community now moves to an era centred on functional characterisation of the genome. This includes understanding sequence and structural variation as well as how information is integrated across multiple homoeologous genomes. This understanding promises to uncover variation previously hidden from natural and human selection due to the often observed functional redundancy between homoeologs. Key functional genomic resources will enable this, including sequenced mutant populations and gene editing technologies which are now available in wheat. Training the next-generation of genomics-enabled researchers will be essential to ensure these advances are quickly translated into farmers' fields.
authors.affiliation: John Innes Centre, Norwich Research Park, Norwich NR4 7UH, United Kingdom. Electronic address: Cristobal.uauy@jic.ac.uk.
authors.forename: Cristobal
authors.initials: C
authors.lastname: Uauy
mesh_terms: D014644:Genetic Variation; D018745:Genome, Plant; D023281:Genomics / Q000639:trends*; D058977:Molecular Sequence Annotation; D011123:Polyploidy; D014908:Triticum / Q000235:genetics*