title: Osteophyte induced lung fibrosis prevalence and osteophyte qualities predicting disease.
abstract: OBJECTIVE
  To determine the prevalence of osteophyte induced lung fibrosis (OIF) and its relationship to osteophyte size, location, and surrounding fat.
  
  
  METHODS
  94 CT scans of the chest were reviewed, size of the largest osteophyte and the presence of fibrosis were recorded.
  
  
  RESULTS
  Presence of fibrosis was higher among patient with large (>10 mm) osteophytes compared to those with small (1-10mm) osteophytes. Age and presence of periosteophyte fat were significantly associated with presence of fibrosis.
  
  
  CONCLUSIONS
  As the size of an osteophyte increases, there is a greater likelihood of lung fibrosis. Subpleural fat protects the lung from OIF.
authors.affiliation: Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY, United States. Electronic address: Mary.Salvatore@mountsinai.org.
authors.forename: Mary
authors.initials: M
authors.lastname: Salvatore
authors.affiliation: Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
authors.forename: Claudia I
authors.initials: CI
authors.lastname: Henschke
authors.affiliation: Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
authors.forename: Rowena
authors.initials: R
authors.lastname: Yip
authors.affiliation: Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
authors.forename: Sukhdeep
authors.initials: S
authors.lastname: Kaur
authors.affiliation: Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
authors.forename: Kunwei
authors.initials: K
authors.lastname: Li
authors.affiliation: Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
authors.forename: Maria
authors.initials: M
authors.lastname: Padilla
authors.affiliation: Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
authors.forename: David
authors.initials: D
authors.lastname: Yankelevitz
mesh_terms: D000273:Adipose Tissue; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008168:Lung / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D054850:Osteophyte / Q000150:complications* / Q000473:pathology; D015995:Prevalence; D011658:Pulmonary Fibrosis / Q000209:etiology*; D014057:Tomography, X-Ray Computed
keywords: Osteophyte; Pulmonary fibrosis; UIP; Usual interstitial pneumonitis