title: Forebrain neurogenesis: From embryo to adult.
abstract: A satellite symposium to the Canadian Developmental Biology Conference 2016 was held on March 16-17, 2016 in Banff, Alberta, Canada, entitledForebrain Neurogenesis:From embryo to adult. TheForebrain Neurogenesissymposium was a focused, high-intensity meeting, bringing together the top Canadian and international researchers in the field. This symposium reported the latest breaking news, along with 'state of the art' techniques to answer fundamental questions in developmental neurobiology. Topics covered ranged from stem cell regulation to neurocircuitry development, culminating with a session focused on neuropsychiatric disorders. Understanding the underlying causes of neurodevelopmental disorders such as autism spectrum disorder (ASD) and attention deficit/hyperactivity disorder (ADHD) is of great interest as diagnoses of these conditions are climbing at alarming rates. For instance, in 2012, the Centers for Disease Control reported that the prevalence rate of ASD in the U.S. was 1 in 88; while more recent data indicate that the number is as high as 1 in 68 (Centers for Disease Control and Prevention MMWR Surveillance Summaries. Vol. 63. No. 2). Similarly, the incidence of ASD is on the rise in Canada, increasing from 1 in 150 in 2000 to 1 in 63 in 2012 in southeastern Ontario (Centers for Disease Control and Prevention). Currently very little is known regarding the deficits underlying these neurodevelopmental conditions. Moreover, the development of effective therapies is further limited by major gaps in our understanding of the fundamental processes that regulate forebrain development and adult neurogenesis. TheForebrain Neurogenesissatellite symposium was thus timely, and it played a key role in advancing research in this important field, while also fostering collaborations between international leaders, and inspiring young researchers.
authors.affiliation: Department of Biochemistry and Molecular Biology, Hotchkiss Brain Institute (HBI), Alberta Children's Hospital Research Institute (ACHRI), University of Calgary, Calgary, Alberta.
authors.forename: Daniel
authors.initials: D
authors.lastname: Dennis
authors.affiliation: Ottawa Hospital Research Institute, Ottawa, Ontario; Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, Ontario.
authors.forename: David
authors.initials: D
authors.lastname: Picketts
authors.affiliation: Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, Ontario.
authors.forename: Ruth S
authors.initials: RS
authors.lastname: Slack
authors.affiliation: Department of Biochemistry and Molecular Biology, Hotchkiss Brain Institute (HBI), Alberta Children's Hospital Research Institute (ACHRI), University of Calgary, Calgary, Alberta; Sunnybrook Research Institute, Biological Sciences, Toronto, Ontario, Canada.
authors.forename: Carol
authors.initials: C
authors.lastname: Schuurmans
keywords: forebrain; neurodevelopment; neurogenesis; neuropsychiatric disorders; stem cell