title: Update on hypoxia-inducible factors and hydroxylases in oxygen regulatory pathways: from physiology to therapeutics.
abstract: The "Hypoxia Nantes 2016" organized its second conference dedicated to the field of hypoxia research. This conference focused on "the role of hypoxia under physiological conditions as well as in cancer" and took place in Nantes, France, in October 6-7, 2016. The main objective of this conference was to bring together a large group of scientists from different spheres of hypoxia. Recent advances were presented and discussed around different topics: genomics, physiology, musculoskeletal, stem cells, microenvironment and cancer, and oxidative stress. This review summarizes the major highlights of the meeting.
authors.affiliation: Target Discovery Institute, University of Oxford; The Francis Crick Institute, London, UK.
authors.forename: Peter
authors.initials: P
authors.lastname: Ratcliffe
authors.affiliation: Oulu Center for Cell-Matrix Research, Biocenter Oulu and Faculty of Biochemistry and Molecular Medicine, University of Oulu, Oulu, Finland.
authors.forename: Peppi
authors.initials: P
authors.lastname: Koivunen
authors.affiliation: Oulu Center for Cell-Matrix Research, Biocenter Oulu and Faculty of Biochemistry and Molecular Medicine, University of Oulu, Oulu, Finland.
authors.forename: Johanna
authors.initials: J
authors.lastname: Myllyharju
authors.affiliation: McGill University and Genome Quebec Innovation Centre, McGill University, Montreal, Canada.
authors.forename: Jiannis
authors.initials: J
authors.lastname: Ragoussis
authors.affiliation: Department of Pathology, Leiden University Medical Center, Leiden, the Netherlands.
authors.forename: Judith Vmg
authors.initials: JV
authors.lastname: Bovée
authors.affiliation: Department of Radiation Oncology, Duke University School of Medicine, Durham, NC, USA.
authors.forename: Ines
authors.initials: I
authors.lastname: Batinic-Haberle
authors.affiliation: INSERM UMR 1229, Regenerative Medicine and Skeleton-RMeS, Team STEP, University of Nantes, UFR Odontology.
authors.forename: Claire
authors.initials: C
authors.lastname: Vinatier
authors.affiliation: UMR 1238 INSERM, Université de Nantes, Faculté de Médecine.
authors.forename: Valérie
authors.initials: V
authors.lastname: Trichet
authors.affiliation: CRCINA, INSERM, Université de Nantes, Nantes.
authors.forename: Florence
authors.initials: F
authors.lastname: Robriquet
authors.affiliation: CRCINA, INSERM, Université de Nantes, Nantes.
authors.forename: Lisa
authors.initials: L
authors.lastname: Oliver
authors.affiliation: CRCINA, INSERM, Université de Nantes, Nantes; Ecole Pratique des Hautes Etudes, PSL Research University, Paris, France.
authors.forename: Betty
authors.initials: B
authors.lastname: Gardie
keywords: cancer; genomics; hypoxia; lipid metabolism; musculoskeletal; oxidative stress