title: Paecilomyces variotii peritonitis in a patient on continuous ambulatory peritoneal dialysis.
abstract: Paecilomyces variotii (P. variotii) is an extremely rare cause of continuous ambulatory peritoneal dialysis (CAPD) peritonitis. When diagnosed, it usually portends poor prognosis. Patient's survival depends on early laboratory diagnosis and proper treatment. We herein report a P. variotii peritonitis in a patient on CAPD which is a quite rare clinical entity. Laboratory diagnosis was confirmed via both morphological analysis and DNA sequencing. Antifungal susceptibility tests were performed and interpreted according to the Clinical Laboratory Standards Institute M38-A2 guidelines. After laboratory diagnosis, the patient was treated succesfully with liposomal amphotericin B and itraconazole combination and the peritoneal catheter was removed. This case is worthy of reporting since P. variotii is an uncommon cause of peritonitis and leads to dilemmas in both laboratory diagnosis and treatment strategies.
authors.affiliation: Giresun University, Medical Faculty, Medical Microbiology Department, 28100 Giresun, Turkey. Electronic address: emeluzunoglu@yahoo.com.
authors.forename: E
authors.initials: E
authors.lastname: Uzunoglu
authors.affiliation: Ozdemir State Hospital, Infectious Disease and Clinical Microbiology Clinic, Giresun, Turkey.
authors.forename: A M
authors.initials: AM
authors.lastname: Sahin
mesh_terms: D000368:Aged; D055499:Catheter-Related Infections / Q000382:microbiology; D002408:Catheters, Indwelling / Q000382:microbiology; D003428:Cross Infection / Q000382:microbiology* / Q000473:pathology; D006801:Humans; D008297:Male; D009181:Mycoses / Q000382:microbiology* / Q000473:pathology; D010143:Paecilomyces / Q000302:isolation & purification / Q000502:physiology; D010531:Peritoneal Dialysis, Continuous Ambulatory / Q000009:adverse effects*; D010538:Peritonitis / Q000382:microbiology* / Q000473:pathology
keywords: Antifungal Susceptibility Test; Continuous ambulatory peritoneal dialysis; Fungal peritonitis; Hyalomycosis; Paecilomyces variotii