title: The Frequency of Primary Sjogren's Syndrome and Fibromyalgia in Irritable Bowel Syndrome.
abstract: OBJECTIVE
  To determine the frequency of sicca complex, Sjogren's Syndrome (SS) and Fibromyalgia (FM) in patients with Irritable Bowel Syndrome (IBS).
  
  
  METHODS
  Seventy seven IBS patients who fulfilled the Rome-III criteria were included in the study. All patients were assessed for FM according to the American College of Rheumatology (ACR) 2010 criteria. After examination for objective evidence of sicca complex by Schirmer test, TBUT and Ocular Staining Score (OSS), serological tests were performed. And the diagnosis of SS was made according to the American College of Rheumatology (ACR) classification criteria for SS - 2012.
  
  
  RESULTS
  Thirteen (16.9%) of IBS patients had FM. Dry eye was detected in 20(26.0%), 7(9.1%) and 29(37.7%) patients by OSS, Schirmer test and TBUT, respectively. Of 77 patients with IBS, the diagnosis of SS was established in two patients (2.6%).
  
  
  CONCLUSIONS
  The frequency of Sjogren's Syndrome among patients with IBS is relatively higher than the general population. All IBS patients should be questioned for dryness of the mouth and eyes, and if necessary, should be evaluated for SS.
authors.affiliation: Funda Erbasan, MD. Specialist, Department of Rheumatology, Antalya Training and Research Hospital, Antalya, Turkey.
authors.forename: Funda
authors.initials: F
authors.lastname: Erbasan
authors.affiliation: Yesim Cekin, MD. Associate Professor, Department of Microbiology, Antalya Training and Research Hospital, Antalya, Turkey.
authors.forename: Yesim
authors.initials: Y
authors.lastname: Cekin
authors.affiliation: Deniz Turgut Coban, MD. Specialist, Department of Ophthalmology, Antalya Training and Research Hospital, Antalya, Turkey.
authors.forename: Deniz Turgut
authors.initials: DT
authors.lastname: Coban
authors.affiliation: Ugur Karasu, MD. Specialist, Department of Rheumatology, Antalya Training and Research Hospital, Antalya, Turkey.
authors.forename: Ugur
authors.initials: U
authors.lastname: Karasu
authors.affiliation: Dinc Suren, MD. Associate Professor, Department of Pathology, Antalya Training and Research Hospital, Antalya, Turkey.
authors.forename: Dinc
authors.initials: D
authors.lastname: Suren
authors.affiliation: Ayhan H. Cekin, MD. Associate Professor, Department of Gastroenterology, Antalya Training and Research Hospital, Antalya, Turkey.
authors.forename: Ayhan H
authors.initials: AH
authors.lastname: Cekin
keywords: Antinuclear antibodies; Fibromyalgia; Irritable Bowel Syndrome; Sjogren’s Syndrome