title: Optic Neuropathy As the Initial Presenting Sign ofN-methyl-d-aspartate (NMDA) Encephalitis.
abstract: A 52-year-old woman presented with painless vision loss for 3 months. She was in custody for allegedly robbing a bank and had recently been diagnosed with paranoid schizophrenia. She had 20/100 VA OD, a 2+RAPD, and optic atrophy. Extensive diagnostic workup including MRI, Fluorescein Angiography, Infectious Disease Panel, lumbar puncture, and leptomeningeal biopsy were unrevealing. Vision in her right eye declined to NLP and her left eye declined to 20/200 VA. Anti N-methyl-D-aspartate (NMDA) Autoimmune Encephalitis was diagnosed based on CSF serology and clinical suspicion. Her clinical course improved as she was treated with corticosteroids and rituximab.
authors.affiliation: Department of Ophthalmology and Visual Sciences, University of Louisville , Louisville, Kentucky, USA.
authors.forename: Mark
authors.initials: M
authors.lastname: Mugavin
authors.affiliation: Department of Ophthalmology and Visual Sciences, University of Louisville , Louisville, Kentucky, USA.
authors.forename: Brett H
authors.initials: BH
authors.lastname: Mueller
authors.affiliation: Department of Neurology, University of Louisville , Louisville, Kentucky, USA.
authors.forename: Masoom
authors.initials: M
authors.lastname: Desai
authors.affiliation: Department of Ophthalmology, University of Cincinnati , Ohio, USA.
authors.forename: Karl C
authors.initials: KC
authors.lastname: Golnik
keywords: NMDA encephalitis; optic neuropathy