title: Functional characterization of biomedical potential of biosurfactant produced byLactobacillus helveticus.
abstract: Various lactic acid bacteria (LAB) have been isolated and screened for biosurfactant production and their biomedical and food applications. Additionally, various different concentrations of the biosurfactant (0.625-25 mg ml-1) were used to evaluate its antimicrobial and antiadhesive potential against a range of pathogenic microorganisms. Biosurfactant was found to be stable to pH changes over a range of 4.0-12.0, being most effective at pH 7 and showed no apparent loss of surface tension and emulsification efficiency after heat treatment at 125 °C for 15 min. Present study demonstrated that biosurfactant obtained fromLactobacillus helveticushas the ability to counteract effectively the initial deposition of biofilm forming pathogens to silicone surfaces and to significantly sluggish biofilm growth.
authors.affiliation: Department of Microbiology, Kurukshetra University, Kurukshetra 136 119, India; School of Biotechnology and Biosciences, Lovely Professional University, Jalandhar, India.
authors.forename: Deepansh
authors.initials: D
authors.lastname: Sharma
authors.affiliation: Department of Microbiology, Kurukshetra University, Kurukshetra 136 119, India.
authors.forename: Baljeet Singh
authors.initials: BS
authors.lastname: Saharan
keywords: Anti-Biofilm; Antiadhesive; Antimicrobial; Biosurfactant; Glycolipid