title: AtSLP2 is an intronless protein phosphatase that co-expresses with intronless mitochondrial pentatricopeptide repeat (PPR) and tetratricopeptide (TPR) protein encoding genes.
abstract: Shewanella-like PPP family phosphatases (SLPs) are a unique lineage of eukaryote PPP-family phosphatases of bacterial origin which are not found in metazoans.1,2Their absence in metazoans is marked by their ancient bacterial origins and presence in plants.1Recently, we found that the SLP2 phosphatase ortholog of Arabidopsis thaliana localized to the mitochondrial intermembrane space (IMS) where it was determined to be activated by mitochondrial intermembrane space protein 40 (MIA40) to regulate seed germination.3Through examination of atslp2 knockout (accelerated germination) and 35S::AtSLP2 over-expressing (delayed germination) plants it was found that AtSLP2 influences Arabidopsis thaliana germination rates via gibberellic acid (GA) biosynthesis.3However, the exact mechanism by which this occurs remains unresolved. To identify potential partners of AtSLP2 in regulating germination through GA, we undertook a gene co-expression network analysis using RNA-sequencing data available through Genevestigator ( https://genevestigator.com/gv/ ).
authors.affiliation: a Department of Biological Sciences , University of Calgary , Calgary , Alberta , Canada.|b Group of Plant Biotechnology, Department of Biology , Swiss Federal Institute of Technology , Zurich , Switzerland.
authors.forename: R Glen
authors.initials: RG
authors.lastname: Uhrig
authors.affiliation: a Department of Biological Sciences , University of Calgary , Calgary , Alberta , Canada.
authors.forename: Greg
authors.initials: G
authors.lastname: Moorhead
mesh_terms: D000040:Abscisic Acid / Q000378:metabolism; D017360:Arabidopsis / Q000378:metabolism* / Q000502:physiology; D029681:Arabidopsis Proteins / Q000235:genetics / Q000378:metabolism*; D018506:Gene Expression Regulation, Plant / Q000235:genetics / Q000502:physiology; D018525:Germination / Q000235:genetics / Q000502:physiology; D005875:Gibberellins / Q000378:metabolism; D008928:Mitochondria / Q000235:genetics / Q000378:metabolism; D010749:Phosphoprotein Phosphatases / Q000235:genetics / Q000378:metabolism; D030821:Plants, Genetically Modified / Q000235:genetics / Q000378:metabolism / Q000502:physiology
chemical_list: D029681:Arabidopsis Proteins; D005875:Gibberellins; D000040:Abscisic Acid; C007842:gibberellic acid; D010749:Phosphoprotein Phosphatases
keywords: Arabidopsis thaliana; co-expression network; intronless genes; mitochondria; protein phosphatase