title: Indications and Outcomes From 32 Consecutive Patients for the Treatment of Rectal Lesions by Transanal Minimally Invasive Surgery.
abstract: BACKGROUND
  The aim of this study was to evaluate the feasibility, safety, perioperative morbidity, and short-term outcomes of the transanal minimally invasive surgery (TAMIS) technique.
  
  
  METHODS
  This is a descriptive review of prospectively collected data from 32 consecutive patients who underwent TAMIS procedures in our colorectal unit over a 40-month period. GelPOINT Path port was used in all cases. Demographic data, indications, tumor characteristics, morbidity, and follow-up data were collected. Primary endpoints included feasibility, safety, perioperative morbidity, and resection quality.
  
  
  RESULTS
  Fifteen adenomas, 12 carcinomas, 1 gastrointestinal stromal tumor, and 1 neuroendocrine tumor were locally excised. Additionally, 3 pelvic abscesses were drained transanally using the TAMIS port. Mean distance from the anal verge was 5.6 ± 1.5 cm. Early postoperative complications occurred in 22%, with only one case of major complication (3.1%) requiring reoperation, and no postoperative mortality. Four carcinomas were understaged (33.3%) and 1 adenoma overstaged (6.7%) preoperatively. Three carcinomas were not suspected preoperatively (25%). Microscopic positive lateral margin was found in one case, and no affected deep margin was found. Fragmentation rate was 6.9%, 2 cases, both lesions over 20 cm2. In cases of fit patients with high-risk carcinomas, 2 underwent immediate salvage surgery and another 2 refused and were treated with adjuvant radiotherapy. With a median follow-up of 26 months, the overall recurrence rate was 10.3%, 1 adenoma and 2 carcinomas.
  
  
  CONCLUSIONS
  TAMIS seems to be a safe and reproducible procedure for local excision of well-selected rectal lesions with low morbidity and good functional outcomes.
authors.affiliation: 1 Hospital Universitario San Agustín, Avilés, Spain.|2 University of Oviedo, Oviedo, Spain.
authors.forename: Luis J
authors.initials: LJ
authors.lastname: García-Flórez
authors.affiliation: 1 Hospital Universitario San Agustín, Avilés, Spain.
authors.forename: Jorge L
authors.initials: JL
authors.lastname: Otero-Díez
authors.affiliation: 1 Hospital Universitario San Agustín, Avilés, Spain.
authors.forename: Ana I
authors.initials: AI
authors.lastname: Encinas-Muñiz
authors.affiliation: 1 Hospital Universitario San Agustín, Avilés, Spain.
authors.forename: Luis
authors.initials: L
authors.lastname: Sánchez-Domínguez
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003111:Colonic Polyps / Q000601:surgery; D013505:Digestive System Surgical Procedures / Q000009:adverse effects / Q000379:methods / Q000706:statistics & numerical data; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D019060:Minimally Invasive Surgical Procedures / Q000009:adverse effects / Q000379:methods / Q000706:statistics & numerical data; D011446:Prospective Studies; D012004:Rectal Neoplasms / Q000601:surgery*; D012007:Rectum / Q000601:surgery*; D016896:Treatment Outcome
keywords: early rectal cancer; rectal adenoma; rectal polyps; transanal endoscopic surgery; transanal minimally invasive surgery