title: Syndrome of Headache Accompanied with Transient Neurologic Deficits and Cerebrospinal Fluid Lymphocytosis.
abstract: The syndrome of headache accompanied with transient neurologic deficits and cerebrospinal fluid lymphocytosis (HaNDL), is a rare, benign and self limiting syndrome. In the 2nd Edition of the International Classification of Headache Disorders, HaNDL syndrome was defined in secondary headache group as "Headache attributed to non-vascular intracranial disorder". The etiology of HaNDL is still unknown. In recent years, some authors have shown that ion channel autoimmunity might at least partially contribute to HaNDL pathogenesis. In this paper, the definition of HaNDL syndrome, clinical picture and epidemiology of HaNDL syndrome, etiopathogenesis, differential diagnosis and treatment will be reviewed with the recent literature.
authors.affiliation: İstanbul University Istanbul Medical Faculty, Department of Neurology, İstanbul, Turkey.
authors.forename: Arzu
authors.initials: A
authors.lastname: Çoban
authors.affiliation: İstanbul University Istanbul Medical Faculty, Department of Neurology, İstanbul, Turkey.
authors.forename: Erkingül
authors.initials: E
authors.lastname: Shugaiv
authors.affiliation: İstanbul University Experimental Research Institute (DETAE), Department of Neuroscience, İstanbul, Turkey.
authors.forename: Erdem
authors.initials: E
authors.lastname: Tüzün
keywords: Headache; cerebrospinal fluid lymphocytosis; transient neurologic deficits