title: Mechanisms of Light-induced Liposome Permeabilization.
abstract: Liposomes have been widely studied for drug delivery applications. The inclusion of photoactive molecules into liposomes opens the possibility of light-controlled cargo release to enhance drug biodistribution or bioavailability at target sites. Membrane permeabilization induced by light can be an effective strategy for enhancing cargo delivery with spatial and temporal control, which holds potential for chemophototherapy approaches. Several diverse mechanisms have been reported including light-induced oxidation, photocrosslinking, photoisomerization, photocleavage and photothermal release. Here, we review selected recent reports of light-triggered cargo release from liposomes.
authors.affiliation: Department of Biomedical Engineering, University at Buffalo, State University of New York, Buffalo, NY, 14260, USA.
authors.forename: Dyego
authors.initials: D
authors.lastname: Miranda
authors.affiliation: Department of Biomedical Engineering, University at Buffalo, State University of New York, Buffalo, NY, 14260, USA.
authors.forename: Jonathan F
authors.initials: JF
authors.lastname: Lovell