title: Warming infusion improves perioperative outcomes of elderly patients who underwent bilateral hip replacement.
abstract: BACKGROUND
  This prospective, randomized, and controlled study was performed to determine the benefits of prewarmed infusion in elderly patients who underwent bilateral hip replacement.
  
  
  METHODS
  Between September 2015 and April 2016, elderly patients who underwent bilateral hips replacement that met the inclusion and exclusion criteria were included in this study. After inclusion, patients were randomized into one of the study groups: in the control group, patients received an infusion of fluid kept at room temperature (22-23°C); in the warming infusion group, patients received an infusion of fluid warmed using an infusion fluid heating apparatus (35°C). Postoperative outcomes, including recovery time, length of hospital stay, visual analogue scale (VAS) score, and postoperative complications rate of patients from both groups, were compared.
  
  
  RESULTS
  A total of 64 patients were included in our study (71.2 ± 7.6 years, 53.1% males), with 32 patients in the control group and 32 patients in warming infusion group. No significant difference was found in terms of demographic data and intraoperative blood transfusion rate between 2 groups (P > 0.05). Patients receiving a prewarmed infusion had a significantly shorter time to spontaneous breath, eye opening, consciousness recovery, and extubation than the control group (P < 0.05). In addition, significant differences were found in Steward score and VAS score between 2 groups (P < 0.05). Moreover, warming infusion group also showed an obviously decreased incidence of shivering and postoperative cognitive dysfunction (P < 0.05).
  
  
  CONCLUSIONS
  A prewarmed infusion could reduce the incidence of perioperative hypothermia and improve outcomes in the elderly during bilateral hip replacement.
authors.affiliation: Department of Anesthesiology Intensive Care Unit, The Second Hospital of Jilin University Department of Spine Surgery, The First Hospital of Jilin University, Changchun, P. R. China.
authors.forename: He
authors.initials: H
authors.lastname: Ma
authors.forename: Bingjie
authors.initials: B
authors.lastname: Lai
authors.forename: Shanshan
authors.initials: S
authors.lastname: Dong
authors.forename: Xinyu
authors.initials: X
authors.lastname: Li
authors.forename: Yunfeng
authors.initials: Y
authors.lastname: Cui
authors.forename: Qianchuang
authors.initials: Q
authors.lastname: Sun
authors.forename: Wenhua
authors.initials: W
authors.lastname: Liu
authors.forename: Wei
authors.initials: W
authors.lastname: Jiang
authors.forename: Feng
authors.initials: F
authors.lastname: Xu
authors.forename: Hui
authors.initials: H
authors.lastname: Lv
authors.forename: Hongyu
authors.initials: H
authors.lastname: Han
authors.forename: Zhenxiang
authors.initials: Z
authors.lastname: Pan
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D019644:Arthroplasty, Replacement, Hip; D005260:Female; D006358:Hot Temperature / Q000627:therapeutic use*; D006801:Humans; D007035:Hypothermia / Q000517:prevention & control*; D007262:Infusions, Intravenous; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D059035:Perioperative Period; D011183:Postoperative Complications / Q000517:prevention & control*; D011446:Prospective Studies