title: New bisesquiterpenoid lactone from the wild rhizome of Atractylodes macrocephala Koidz grown in Qimen.
abstract: The rhizomes of Atractylodes macrocephala are used as both a food source and traditional Chinese medicine in China. A phytochemical investigation was carried out on wild A. macrocephala grown in Qimen County in eastern China, and yielded a novel bisesquiterpenoid lactone, namely, biatractylenolide II (1), along with two known compounds, atractylenolide II (2) and taraxeryl acetate (3). The structure and relative configuration of the new compound were elucidated mainly by 1D and 2D NMR spectroscopic methods in combination with HRESIMS experiments. This paper describes the isolation and structural elucidation of the new bisesquiterpenoid lactone (1).
authors.affiliation: a School of Pharmacy , Anhui University of Chinese Medicine , Hefei , P.R. China.
authors.forename: Yunzhi
authors.initials: Y
authors.lastname: Li
authors.affiliation: a School of Pharmacy , Anhui University of Chinese Medicine , Hefei , P.R. China.
authors.forename: Min
authors.initials: M
authors.lastname: Dai
authors.affiliation: a School of Pharmacy , Anhui University of Chinese Medicine , Hefei , P.R. China.
authors.forename: Daiyin
authors.initials: D
authors.lastname: Peng
mesh_terms: D031174:Atractylodes / Q000737:chemistry*; D002681:China; D007783:Lactones / Q000737:chemistry* / Q000302:isolation & purification; D015394:Molecular Structure; D064209:Phytochemicals / Q000737:chemistry / Q000302:isolation & purification; D027343:Rhizome / Q000737:chemistry*; D012717:Sesquiterpenes / Q000737:chemistry* / Q000302:isolation & purification
chemical_list: D007783:Lactones; D064209:Phytochemicals; D012717:Sesquiterpenes; C000601993:biatractylenolide
keywords: Atractylodes macrocephala; biatractylenolide II; bisesquiterpenoid lactone; chemical constituents