title: Development of nanoparticle-based optical sensors for pathogenic bacterial detection.
abstract: BACKGROUND
  Pathogenic bacteria contribute to various globally important diseases, killing millions of people each year. Various fields of medicine currently benefit from or may potentially benefit from the use of nanotechnology applications, in which there is growing interest. Disease-related biomarkers can be rapidly and directly detected by nanostructures, such as nanowires, nanotubes, nanoparticles, cantilevers, microarrays, and nanoarrays, as part of an accurate process characterized by lower sample consumption and considerably higher sensitivity. There is a need for accurate techniques for pathogenic bacteria identification and detection to allow the prevention and management of pathogenic diseases and to assure food safety.
  
  
  CONCLUSIONS
  The focus of this review is on the current nanoparticle-based techniques for pathogenic bacterial identification and detection using these applications.
authors.affiliation: Department of Nanomedicine, "Octavian Fodor" Gastroenterology Institute, 19-21 Croitorilor Street, Cluj-Napoca, Romania.|Department of Physiology, "Iuliu Hatieganu" University of Medicine and Pharmacy, 3-5 Clinicilor Street, Cluj-Napoca, Romania.
authors.forename: Teodora
authors.initials: T
authors.lastname: Mocan
authors.affiliation: Department of Nanomedicine, "Octavian Fodor" Gastroenterology Institute, 19-21 Croitorilor Street, Cluj-Napoca, Romania.|3rd Surgery Clinic, "Iuliu Hatieganu" University of Medicine and Pharmacy, 19-21 Croitorilor Street, Cluj-Napoca, Romania.
authors.forename: Cristian T
authors.initials: CT
authors.lastname: Matea
authors.affiliation: 3rd Gastroenterology Department, "Iuliu Hatieganu" University of Medicine and Pharmacy, 19-21 Croitorilor Street, Cluj-Napoca, Romania.
authors.forename: Teodora
authors.initials: T
authors.lastname: Pop
authors.affiliation: 3rd Gastroenterology Department, "Iuliu Hatieganu" University of Medicine and Pharmacy, 19-21 Croitorilor Street, Cluj-Napoca, Romania.
authors.forename: Ofelia
authors.initials: O
authors.lastname: Mosteanu
authors.affiliation: Department of Clinical Pharmacology, "Iuliu Hatieganu" University of Medicine and Pharmacy, 3-5 Clinicilor Street, Cluj-Napoca, Romania.
authors.forename: Anca Dana
authors.initials: AD
authors.lastname: Buzoianu
authors.affiliation: Department of Nanomedicine, "Octavian Fodor" Gastroenterology Institute, 19-21 Croitorilor Street, Cluj-Napoca, Romania.|3rd Surgery Clinic, "Iuliu Hatieganu" University of Medicine and Pharmacy, 19-21 Croitorilor Street, Cluj-Napoca, Romania.
authors.forename: Cosmin
authors.initials: C
authors.lastname: Puia
authors.affiliation: Department of Nanomedicine, "Octavian Fodor" Gastroenterology Institute, 19-21 Croitorilor Street, Cluj-Napoca, Romania. cornel.iancu@umfcluj.ro.|3rd Surgery Clinic, "Iuliu Hatieganu" University of Medicine and Pharmacy, 19-21 Croitorilor Street, Cluj-Napoca, Romania. cornel.iancu@umfcluj.ro.
authors.forename: Cornel
authors.initials: C
authors.lastname: Iancu
authors.affiliation: Department of Nanomedicine, "Octavian Fodor" Gastroenterology Institute, 19-21 Croitorilor Street, Cluj-Napoca, Romania. mocanlucian@yahoo.com.|3rd Surgery Clinic, "Iuliu Hatieganu" University of Medicine and Pharmacy, 19-21 Croitorilor Street, Cluj-Napoca, Romania. mocanlucian@yahoo.com.
authors.forename: Lucian
authors.initials: L
authors.lastname: Mocan
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry; D001419:Bacteria / Q000302:isolation & purification*; D006046:Gold / Q000737:chemistry; D053758:Nanoparticles / Q000737:chemistry*; D036103:Nanotechnology / Q000379:methods*; D037742:Nanotubes, Carbon / Q000737:chemistry; D045663:Quantum Dots / Q000737:chemistry; D012834:Silver / Q000737:chemistry; D014774:Virulence
chemical_list: D000900:Anti-Bacterial Agents; D037742:Nanotubes, Carbon; D012834:Silver; D006046:Gold
keywords: Antibiotic resistance; Bacteria; Detection assay; Nanoparticles