title: A Review of Diagnostic Methods for Invasive Fungal Diseases: Challenges and Perspectives.
abstract: Invasive fungal diseases are associated with a high morbidity and mortality, particularly in the context of immunosuppression. Diagnosis of invasive fungal diseases is usually complicated by factors such as poor clinical suspicion and unspecific clinical findings. Access to modern diagnostic tools is frequently limited in developing countries. Here, we describe five real-life clinical cases from a Brazilian tertiary hospital, in order to illustrate how to best select diagnostic tests in patients with different fungal infections.
authors.affiliation: Hospital de Clinicas de Porto Alegre, Porto Alegre, Brazil.|Centro Universitário La Salle Canoas, Canoas, Brazil.
authors.forename: Diego R
authors.initials: DR
authors.lastname: Falci
authors.affiliation: Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, Brazil.|Santa Casa de Misericordia de Porto Alegre, Porto Alegre, Brazil.
authors.forename: Claudio M B
authors.initials: CMB
authors.lastname: Stadnik
authors.affiliation: Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, Brazil. pasqualotto@santacasa.tche.br.|Santa Casa de Misericordia de Porto Alegre, Porto Alegre, Brazil. pasqualotto@santacasa.tche.br.
authors.forename: Alessandro C
authors.initials: AC
authors.lastname: Pasqualotto
keywords: Antigen detection; Beta-D-glucan; Galactomannan; MALDI-TOF; PCR