title: Immunodeficiencies Associated with Abnormal Newborn Screening for T Cell and B Cell Lymphopenia.
abstract: Newborn screening for SCID has revealed the association of low T cells with a number of unexpected syndromes associated with low T cells, some of which were not appreciated to have this feature. This review will discuss diagnostic approaches and the features of some of the syndromes likely to be encountered following newborn screening for immune deficiencies.
authors.affiliation: Division of Allergy Immunology, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.
authors.forename: Soma
authors.initials: S
authors.lastname: Jyonouchi
authors.affiliation: Division of Allergy and Immunology, Cohen Children's Medical Center of New York, Hofstra Northwell School of Medicine, Hempstead, NY, USA.
authors.forename: Artemio M
authors.initials: AM
authors.lastname: Jongco
authors.affiliation: Division of Allergy, Immunology and Blood and Marrow Transplantation, Department of Pediatrics, University of California San Francisco, and UCSF Benioff Children's Hospital, San Francisco, CA, USA.
authors.forename: Jennifer
authors.initials: J
authors.lastname: Puck
authors.affiliation: Division of Allergy Immunology, The Children's Hospital of Philadelphia, Philadelphia, PA, USA. sullivak@mail.med.upenn.edu.
authors.forename: Kathleen E
authors.initials: KE
authors.lastname: Sullivan
mesh_terms: D001402:B-Lymphocytes / Q000473:pathology*; D006801:Humans; D007153:Immunologic Deficiency Syndromes / Q000175:diagnosis*; D007231:Infant, Newborn; D008231:Lymphopenia / Q000175:diagnosis*; D015997:Neonatal Screening; D016511:Severe Combined Immunodeficiency / Q000175:diagnosis*; D013601:T-Lymphocytes / Q000473:pathology*
keywords: Immunology; Low T cells; NBS; Newborn screen