title: [Role of substance P and calcitonin gene-related peptide in bone metabolism].
abstract: Substance P (SP) and calcitonin gene-related peptide (CGRP) are the neuropeptides released from the sensory nerve endings. Neuropeptides play a role in bone and the relevant organs. It exerts functions in regulation of the bone metabolism, fracture healing and pain by a certain way. The biological properties and distributions of SP and CGRP are closely related to the pathogenesis and development of bone metabolism, fracture healing and pain.
authors.affiliation: Department of Bone and Joint Surgery, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200127, China.
authors.forename: Shuanglei
authors.initials: S
authors.lastname: Wang
authors.affiliation: Department of Anesthesiology, Renji Hospital,  School of Medicine, Shanghai Jiaotong University, Shanghai 200127, China.
authors.forename: Jie
authors.initials: J
authors.lastname: Xiao
authors.affiliation: Department of Bone and Joint Surgery, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200127, China.
authors.forename: Zhanchun
authors.initials: Z
authors.lastname: Li
mesh_terms: D001842:Bone and Bones / Q000378:metabolism*; D015740:Calcitonin Gene-Related Peptide / Q000502:physiology*; D017102:Fracture Healing; D006801:Humans; D010146:Pain / Q000209:etiology; D013373:Substance P / Q000502:physiology*
chemical_list: D013373:Substance P; D015740:Calcitonin Gene-Related Peptide