title: Relationship between gastroesophageal reflux disease and Ph nose and salivary: proposal of a simple method outpatient in patients adults.
abstract: BACKGROUND
  The frequency of gastroesophageal reflux disease (GERD) is increasing, in part through easy inspection of the upper digestive tract, but especially for a real spread of the disease as a consequence of modernity, lifestyle, incorrect dietary rules, and stress arising from social norms. It is a common chronic gastrointestinal disorder in Europe and the United States.
  
  
  METHODS
  The aim of our study is to highlight a relationship between gastroesophageal reflux disease and salivary pH as evidenced by indicator strips, especially in the outpatient field. Twenty adult subjects (10 males and 10 females) aged between 18 and 50 years (GROUP A)_ were selected. How to control a homogeneous group of 20 patients without GERD, or from any type of allergies (GROUP B) was enlisted.
  
  
  RESULTS
  This method has provided excellent results showing no difference in the measured values compared with the traditional instrumental measurement.
  
  
  CONCLUSIONS
  Our study has allowed us to observe a strong correlation between the saliva pH, nasal cavities and the interaction between the two districts, and could be the basis for a diagnosis of GERD especially in primary health care clinics and in the initial stage of the disease.
authors.affiliation: Department of Head and Neck. University of Naples Federico II, Naples, Italy.
authors.forename: Arturo Armone
authors.initials: AA
authors.lastname: Caruso
authors.affiliation: Department of Head and Neck. University of Naples Federico II, Naples, Italy.
authors.forename: Salvatore
authors.initials: S
authors.lastname: Del Prete
authors.affiliation: Department of Pharmacy, University of Naples Federico II, Naples, Italy.
authors.forename: Lydia
authors.initials: L
authors.lastname: Ferrara
authors.affiliation: Department of Medical and Surgical Sciences, University of Catanzaro, Catanzaro, Italy.
authors.forename: Raffaele
authors.initials: R
authors.lastname: Serra
authors.affiliation: Department of Advanced Biomedical Sciences. University of Naples Federico II, Naples, Italy.
authors.forename: Donato Alessandro
authors.initials: DA
authors.lastname: Telesca
authors.affiliation: Department of Advanced Biomedical Sciences. University of Naples Federico II, Naples, Italy.
authors.forename: Simona
authors.initials: S
authors.lastname: Ruggiero
authors.affiliation: Department of Advanced Biomedical Sciences. University of Naples Federico II, Naples, Italy.
authors.forename: Teresa
authors.initials: T
authors.lastname: Russo
authors.affiliation: Department of Advanced Biomedical Sciences, University Federico II of Naples. School of Medicine, Naples, Italy, Via Sergio Pansini 5, 80131, Napoli.|Department of Advanced Biomedical Sciences. University of Naples Federico II, Naples, Italy.
authors.forename: Luigi
authors.initials: L
authors.lastname: Sivero
keywords: Chronic rhinitis; Gastro-esophageal reflux disease GERD; Laryngeal-pharyngeal reflux LPR; Ph