title: Synthesis and characterization of Bioglass-based bone grafts with Gelatine substitution for biomedical applications.
abstract: BACKGROUND
  Syntesizing alternative bone graft materials are important in biomedical applications. Their morphology, mechanical properties and cell viability plays an important role in tissue engineering.
  
  
  OBJECTIVE
  Bioglass (B) based bone grafts with Gelatin (G) substitution were syntesized via the sol-gel method and were compared with various Gelatin and Bioglass concentrations (wt%).
  
  
  METHODS
  Syntesized bone grafts were characterized by Scanning Electron Microscopy (SEM) and X-ray diffraction (XRD) to show the structural and morphological changes of the fabricated B-based bone grafts.
  
  
  RESULTS
  It was demonstrated that the concentration of pore size increased with increasing amounts of Gelatin in wt%. The biograft-B40G20 produced the highest flexture strength and hardness. Increasing the pore size caused a decrease in hardness and flexture stress of B-based biografts.
  
  
  CONCLUSIONS
  Cell viability tests were conducted on the fabricated biografts and it was shown that the cell viability increased in fabricated B-based bone grafts.
authors.affiliation: Dept Metallurgy and Mater Eng, Faculty of Chemical and Metallurgy, Yildiz Technical University, Istanbul, Turkey. E-mail: baksakal@yildiz.edu.tr.|Dept of Mech Eng, Engineering Faculty, Munzur University, Tunceli, Turkey. E-mail: baksakal2@gmail.com.
authors.forename: B
authors.initials: B
authors.lastname: Aksakal
authors.affiliation: Vocational School of Technical Sci, Adiyaman University, Adiyaman, Turkey. E-mail: mdemirel@adiyaman.edu.tr.
authors.forename: M
authors.initials: M
authors.lastname: Demirel
mesh_terms: D018786:Bone Substitutes / Q000138:chemical synthesis / Q000737:chemistry*; D002470:Cell Survival; D002516:Ceramics / Q000138:chemical synthesis / Q000737:chemistry*; D005780:Gelatin / Q000138:chemical synthesis / Q000737:chemistry*; D006244:Hardness; D006801:Humans; D008422:Materials Testing; D010006:Osteoblasts / Q000166:cytology; D044367:Phase Transition; D054457:Tissue Scaffolds / Q000737:chemistry*
chemical_list: C022107:Bioglass; D018786:Bone Substitutes; D005780:Gelatin
keywords: Bioglass; cell viability; mechanical properties; sol gel