title: [Gardner-Diamond syndrome in a young man: A case report and literature review].
abstract: BACKGROUND
  Gardner-Diamond syndrome is a rare condition secondary to a sensitization to self-erythrocytes. It is predominantly seen in women and presents as a painful ecchymotic disorder. An underlying psychiatric disease or a triggering psychological stress is of important diagnostic value.
  
  
  METHODS
  We report a 24-year-old patient who presented with intermittent spontaneous painful ecchymosis since 5 years. Complementary investigations failed to identify an organic disorder. Gardner-Diamond syndrome was retained because of the clinical presentation, the negativity of diagnostic work-up and the identification of a psychological trauma. Patient management (pain, psychological support) is difficult, justifying a multidisciplinary approach.
  
  
  CONCLUSIONS
  Gardner-Diamond syndrome is a rare and unrecognized disorder, which should be discussed in the presence of ecchymotic or purpuric lesions that do not have a diagnostic orientation. Early recognition of this disorder enables initiation of an appropriate management, but also limits unnecessary additional explorations.
authors.affiliation: Centre de référence des maladies vasculaires rares, hôpital européen Georges-Pompidou, AP-HP, 75908 Paris cedex 15, France; Médecine interne et médecine vasculaire, hôpital Saint-Éloi, CHRU de Montpellier, 34295 Montpellier cedex 5, France.
authors.forename: P
authors.initials: P
authors.lastname: Henneton
authors.affiliation: Centre de référence des maladies vasculaires rares, hôpital européen Georges-Pompidou, AP-HP, 75908 Paris cedex 15, France.
authors.forename: M
authors.initials: M
authors.lastname: Frank
authors.affiliation: Laboratoire d'immunologie, hôpital européen Georges-Pompidou, AP-HP, 75908 Paris cedex 15, France.
authors.forename: E
authors.initials: E
authors.lastname: Litvinova
authors.affiliation: Centre de référence des maladies vasculaires rares, hôpital européen Georges-Pompidou, AP-HP, 75908 Paris cedex 15, France.
authors.forename: S
authors.initials: S
authors.lastname: Miranda
authors.affiliation: Centre de référence des maladies vasculaires rares, hôpital européen Georges-Pompidou, AP-HP, 75908 Paris cedex 15, France.
authors.forename: E
authors.initials: E
authors.lastname: Messas
authors.affiliation: Service d'hématologie biologique, hôpital européen Georges-Pompidou, AP-HP, 20, rue Leblanc, 75908 Paris cedex 15, France. Electronic address: luc.darnige@aphp.fr.
authors.forename: L
authors.initials: L
authors.lastname: Darnige
mesh_terms: D001327:Autoimmune Diseases / Q000175:diagnosis* / Q000235:genetics / Q000473:pathology; D003937:Diagnosis, Differential; D005162:Factitious Disorders / Q000175:diagnosis* / Q000235:genetics / Q000473:pathology; D006801:Humans; D008297:Male; D011618:Psychotic Disorders / Q000175:diagnosis* / Q000235:genetics / Q000473:pathology; D017445:Skin Diseases, Vascular / Q000175:diagnosis* / Q000235:genetics / Q000473:pathology; D055815:Young Adult
keywords: Autoerythrocyte sensitization syndrome; Gardner–Diamond syndrome; Painful bruising syndrome; Psychogenic purpura; Purpura psychogénique; Syndrome de Gardner-Diamond; Syndrome des ecchymoses douloureuses; Syndrome d’autosensibilisation érythrocytaire