title: Community-acquired urinary tract infections caused byBurkholderiacepaciacomplex in patients with no underlying risk factor.
abstract: Introduction.Urinary tract infections (UTIs) remain common infections diagnosed in outpatients as well as hospitalized patients. Community-acquired UTIs are generally caused byEscherichia coliand other members of the familyEnterobacteriaceae.Burkholderiacepaciais an opportunistic pathogen mainly affecting immunocompromised and hospitalized patients, particularly those who have received prior broad-spectrum antibacterial therapy.Case presentation.Urine samples were collected from 157 outpatients clinically diagnosed with UTI and from 100 healthy control subjects. Samples were cultured on differential media and non-motile lactose-non-fermentors were identified via the Remel RapID ONE system. The isolates were tested by the disc diffusion method against 17 antimicrobial agents.Burkholderiawas isolated as a single organism from four patients having uncomplicated infections, and one from recurrent infection. None of these patients had an underlying risk factor for this pathogen. Identification of these isolates by the Remel-RapID ONE system was confirmed byrecAgene amplification. The four isolates were resistant to lincomycin, nalidixic acid, oxacillin and penicillin G. These cases received monotherapy of oral co-trimoxazole.Conclusions. Our findings alert urologists and diagnostic laboratories to the potential ofB.cepaciacomplex infections in similar cases, and that this bacterium should not be ruled out.
authors.affiliation: Department of Laboratory Medical Sciences, Jordan University of Science and Technology , Irbid , Jordan.
authors.forename: Laila
authors.initials: L
authors.lastname: Nimri
authors.affiliation: Department of Laboratory Medical Sciences, Jordan University of Science and Technology , Irbid , Jordan.
authors.forename: Mamuno
authors.initials: M
authors.lastname: Sulaiman
authors.affiliation: Department of General and Pediatric Surgery, Jordan University of Science and Technology , Irbid , Jordan.
authors.forename: Osama Bani
authors.initials: OB
authors.lastname: Hani
keywords: Burkholderia cepacia; antimicrobial susceptibility pattern; community-acquired; urinary tract infections