title: Future Prospects of Biologic Therapies for Immunologic Diseases.
abstract: This article presents an overview of future uses for biologic therapies in the treatment of immunologic and allergic conditions. Discussion is centered on the use of existing therapies outside of their current indication or on new therapies that are close to approval. This information may help familiarize practicing allergists and immunologists with therapies they may soon encounter in their practice as well as help identify conditions and treatments that will require further study in the near future.
authors.affiliation: Division of Allergy and Immunology, Children's Hospital of Richmond, Virginia Commonwealth University, CHoR Pavilion, 5th Floor, 1000 East Broad Street, Richmond, VA 23298-0225, USA. Electronic address: santhosh.kumar@vcuhealth.org.
authors.forename: Santhosh
authors.initials: S
authors.lastname: Kumar
authors.affiliation: Division of Allergy and Immunology, Children's Hospital of Richmond, Virginia Commonwealth University, CHoR Pavilion, 5th Floor, 1000 East Broad Street, Richmond, VA 23298-0225, USA; Division of Rheumatology, Allergy, and Immunology, Virginia Commonwealth University, McGuire Hall, Room 4-115A, 1112 East Clay Street, Richmond, VA 23298-0263, USA; Department of Microbiology and Immunology, Virginia Commonwealth University, 1101 East Marshall Street, P.O. Box 980678, Richmond, VA 23298, USA.
authors.forename: Brant R
authors.initials: BR
authors.lastname: Ward
authors.affiliation: Division of Allergy and Immunology, Children's Hospital of Richmond, Virginia Commonwealth University, CHoR Pavilion, 5th Floor, 1000 East Broad Street, Richmond, VA 23298-0225, USA.
authors.forename: Anne-Marie
authors.initials: AM
authors.lastname: Irani
mesh_terms: D000888:Antibodies, Anti-Idiotypic / Q000494:pharmacology / Q000627:therapeutic use; D000911:Antibodies, Monoclonal / Q000494:pharmacology / Q000627:therapeutic use; D001688:Biological Products / Q000494:pharmacology / Q000627:therapeutic use; D001691:Biological Therapy / Q000379:methods / Q000639:trends; D016207:Cytokines / Q000037:antagonists & inhibitors / Q000378:metabolism; D003888:Desensitization, Immunologic; D019468:Disease Management; D006801:Humans; D007154:Immune System Diseases / Q000175:diagnosis / Q000276:immunology / Q000378:metabolism / Q000628:therapy*; D058990:Molecular Targeted Therapy; D018121:Receptors, Cytokine / Q000037:antagonists & inhibitors / Q000378:metabolism; D015398:Signal Transduction / Q000187:drug effects
chemical_list: D000888:Antibodies, Anti-Idiotypic; D000911:Antibodies, Monoclonal; D001688:Biological Products; D016207:Cytokines; D018121:Receptors, Cytokine; C026408:anti-IgE antibodies
keywords: Asthma; Atopic dermatitis; Biologic; Churg-Strauss syndrome; Hemophagocytic lymphohistiocytosis; Immune dysregulation; Immunodeficiency; Mastocytosis