title: Parallel Detection of Refractive Index Changes in a Porous Silicon Microarray Based on Digital Images.
abstract: A new technique for the refractive index change with high-sensitivity measurements was proposed by the digital image of porous silicon (PSi) microarray utilization in this paper. Under the irradiation of a He-Ne laser, the surface images of the PSi array cells with the microcavity structure were obtained by the digital imaging equipment, whereas the refractive index change of each array cells was detected by calculating the average gray value of the image and the refractive index change measurement sensitivity was 10-4. This technique could be utilized in the label-free and parallel detection of refraction index changes induced by a biological reaction in the microarray or the chip.
authors.affiliation: School of Physical Science and Technology, Xinjiang University, Urumqi 830046, China. lcxxju@163.com.
authors.forename: Chuanxi
authors.initials: C
authors.lastname: Li
authors.affiliation: College of Information Science and Engineering, Xinjiang University, Urumqi 830046, China. jzhh@xju.edu.cn.
authors.forename: Zhenhong
authors.initials: Z
authors.lastname: Jia
authors.affiliation: School of Physical Science and Technology, Xinjiang University, Urumqi 830046, China. pl211869@sina.com.
authors.forename: Peng
authors.initials: P
authors.lastname: Li
authors.affiliation: The First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China. dr.wenhao@163.com.
authors.forename: Hao
authors.initials: H
authors.lastname: Wen
authors.affiliation: The First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China. lvgdng@163.com.
authors.forename: Guodong
authors.initials: G
authors.lastname: Lv
authors.affiliation: College of Information Science and Engineering, Xinjiang University, Urumqi 830046, China. hxhdemail@sina.com.
authors.forename: Xiaohui
authors.initials: X
authors.lastname: Huang
keywords: average gray value; digital Images; porous silicon microarray; refraction index