title: A case report of hereditary spherocytosis with concomitant chronic myelocytic leukemia.
abstract: Hereditary spherocytosis (HS) and Chronic myelocytic leukemia (CML) are both life threatening hemotologic diseases. They are rarely seen to occur simultaneously in one individual patient. Here we demonstrate a case of HS associated with CML in this study. The patient is a young female, diagnosed with HS in 2005, and was given partial embolization of the splenic artery. She got significant remission after the procedure. In 2008, she was found abnormal in blood routine test, after bone marrow routine, chromosome and fusion gene tests, she was diagnosed with CML (chronic phase). She did not receive regular treatment until 3 months prior, and is currently being treated with Dasatimib. She achieved hematological remission, but had no significant improvement in chromosome and fusion gene figures. Due to her severe condition of hemolysis, a splenectomy or an allogeneic hematopoietic stem cell transplantation is considered.
authors.affiliation: Department of Hematology, the People's Hospital of Liushui, Lishui 323000, Zhejiang Province, China.
authors.forename: Wang
authors.initials: W
authors.lastname: Xiaoqiu
authors.affiliation: Department of Hematology, the People's Hospital of Liushui, Lishui 323000, Zhejiang Province, China.
authors.forename: Fang
authors.initials: F
authors.lastname: Bingmu
authors.affiliation: Department of Hematology, the People's Hospital of Liushui, Lishui 323000, Zhejiang Province, China.
authors.forename: Jiang
authors.initials: J
authors.lastname: Jinhong
authors.affiliation: Department of Hematology, the People's Hospital of Liushui, Lishui 323000, Zhejiang Province, China.
authors.forename: Qu
authors.initials: Q
authors.lastname: Zhigang
authors.affiliation: Department of Hematology, the People's Hospital of Liushui, Lishui 323000, Zhejiang Province, China.
authors.forename: Ma
authors.initials: M
authors.lastname: Guangli
authors.affiliation: Department of Hematology, the People's Hospital of Liushui, Lishui 323000, Zhejiang Province, China.
authors.forename: Liu
authors.initials: L
authors.lastname: Yonghua
authors.affiliation: Department of Hematology, the People's Hospital of Liushui, Lishui 323000, Zhejiang Province, China.
authors.forename: Wang
authors.initials: W
authors.lastname: Xiaoli
keywords: Case report; Chronic myelocytic leukemia; Hereditary spherocytosis