title: Usefulness of 68Ga-DOTA-RGD (αvβ3) PET/CT Imaging in Thyroglobulin Elevation With Negative Iodine Scintigraphy.
abstract: TENIS (thyroglobulin elevation with negative iodine scintigraphy) syndrome in patients with differentiated thyroid carcinoma is not a rare finding. In such patients, F-FDG PET/CT can help in disease evaluation. RGD tripeptide, used for imaging angiogenesis, may also help in disease detection in patients with negative radioiodine whole-body scan. We present 1 such case in whom Ga-RGD tripeptide imaging was helpful in disease detection in the setting of negative radioiodine whole-body scan.
authors.affiliation: From the Department of Nuclear Medicine, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
authors.forename: Rakhee
authors.initials: R
authors.lastname: Vatsa
authors.forename: Jaya
authors.initials: J
authors.lastname: Shykla
authors.forename: Bhagwant Rai
authors.initials: BR
authors.lastname: Mittal
authors.forename: Priya
authors.initials: P
authors.lastname: Bhusari
authors.forename: Apurva
authors.initials: A
authors.lastname: Sood
authors.forename: Rajender Kumar
authors.initials: RK
authors.lastname: Basher
authors.forename: Anish
authors.initials: A
authors.lastname: Bhattacharya
mesh_terms: D006573:Heterocyclic Compounds, 1-Ring; D006801:Humans; D007457:Iodine Radioisotopes; D008297:Male; D009842:Oligopeptides; D000072078:Positron Emission Tomography Computed Tomography; D013954:Thyroglobulin / Q000378:metabolism*; D013964:Thyroid Neoplasms / Q000000981:diagnostic imaging* / Q000378:metabolism* / Q000473:pathology; D051598:Whole Body Imaging; D055815:Young Adult
chemical_list: C000605805:68Ga-DOTA-Arg-Gly-Asp; D006573:Heterocyclic Compounds, 1-Ring; D007457:Iodine Radioisotopes; D009842:Oligopeptides; D013954:Thyroglobulin