title: Clinical features of ectomesenchymal chondromyxoid tumors: A systematic review of the literature.
abstract: Ectomesenchymal chondromyxoid tumors are rare, benign neoplasms of the head and neck most commonly found within the oral cavity. While histopathological evaluation has been the primary focus of prior studies, clinical characterization of this rare entity currently remains sparse. Thus, this study was performed to provide insights into the clinical characteristics of ectomesenchymal chondromyxoid tumors to aid clinicians in distinguishing the lesion from other benign and malignant processes for a more accurate diagnosis and treatment. Moreover, this study includes a unique case of ectomesenchymal chondromyxoid tumor arising in the base of tongue, now the fourth to arise at that anatomic site. Including this case, a systematic review of the literature identified only 60 individual cases reported thus far. This study provides a detailed analysis of all 60 cases including demographics, clinical presentation, radiographic imaging, follow-up, and recurrence rate.
authors.affiliation: Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, 135 Rutledge Avenue, MSC 550, Charleston, SC 29425, USA. Electronic address: kato@musc.edu.
authors.forename: Masanari G
authors.initials: MG
authors.lastname: Kato
authors.affiliation: Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, 135 Rutledge Avenue, MSC 550, Charleston, SC 29425, USA. Electronic address: evrenerkul@yahoo.com.
authors.forename: Evren
authors.initials: E
authors.lastname: Erkul
authors.affiliation: Department of Pathology, Medical University of South Carolina, 171 Ashley Avenue, MSC 908, Charleston, SC 29425, USA. Electronic address: andino@musc.edu.
authors.forename: Kendall S
authors.initials: KS
authors.lastname: Brewer
authors.affiliation: Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, 135 Rutledge Avenue, MSC 550, Charleston, SC 29425, USA. Electronic address: harruff@musc.edu.
authors.forename: Emily E
authors.initials: EE
authors.lastname: Harruff
authors.affiliation: Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, 135 Rutledge Avenue, MSC 550, Charleston, SC 29425, USA. Electronic address: nguyensh@musc.edu.
authors.forename: Shaun A
authors.initials: SA
authors.lastname: Nguyen
authors.affiliation: Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, 135 Rutledge Avenue, MSC 550, Charleston, SC 29425, USA. Electronic address: headneck@musc.edu.
authors.forename: Terry A
authors.initials: TA
authors.lastname: Day
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001706:Biopsy; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D008637:Mesenchymoma / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D008875:Middle Aged; D014062:Tongue Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D055815:Young Adult
keywords: Base of tongue; Ectomesenchymal chondromyxoid tumors; Head and neck tumors; Oral tongue; Tongue neoplasms