title: Bifunctional Oxo-Tethered Ruthenium Complex Catalyzed Asymmetric Transfer Hydrogenation of Aryl N-Heteroaryl Ketones.
abstract: A facile asymmetric transfer hydrogenation of ortho-substituted aryl N-heteroaryl ketones and non-ortho-substituted N-oxide of aryl N-heteroaryl ketones using a readily available oxo-tethered ruthenium complex as a catalyst and sodium formate as a hydrogen source in an aqueous solution has been discovered. A variety of chiral aryl N-heteroaryl methanols were obtained with up to 99.9% ee.
authors.affiliation: Hubei Key Laboratory of Natural Products Research and Development, College of Biological and Pharmaceutical Sciences, China Three Gorges University , Yichang 443002, China.
authors.forename: Baigui
authors.initials: B
authors.lastname: Wang
authors.affiliation: Hubei Key Laboratory of Natural Products Research and Development, College of Biological and Pharmaceutical Sciences, China Three Gorges University , Yichang 443002, China.
authors.forename: Haifeng
authors.identifier: 0000-0002-2710-9570
authors.initials: H
authors.lastname: Zhou
authors.affiliation: Hubei Key Laboratory of Natural Products Research and Development, College of Biological and Pharmaceutical Sciences, China Three Gorges University , Yichang 443002, China.
authors.forename: Guoren
authors.initials: G
authors.lastname: Lu
authors.affiliation: Hubei Key Laboratory of Natural Products Research and Development, College of Biological and Pharmaceutical Sciences, China Three Gorges University , Yichang 443002, China.
authors.forename: Qixing
authors.initials: Q
authors.lastname: Liu
authors.affiliation: Hubei Key Laboratory of Natural Products Research and Development, College of Biological and Pharmaceutical Sciences, China Three Gorges University , Yichang 443002, China.
authors.forename: Xiaolan
authors.initials: X
authors.lastname: Jiang