title: Remote orbital recurrence of olfactory neuroblastoma (esthesioneuroblastoma).
abstract: Olfactory neuroblastoma is a rare and often locally aggressive malignancy that invades the orbit via local destruction. It is known to recur in a delayed fashion, particularly to the neck lymph nodes. This is a case of a 65-year-old gentleman who presents with recurrence in the orbit and a neck lymph node 19 years after treatment for his initial disease. This report describes the longest known interval in orbital recurrence and should alert the monitoring physician that extreme delays in recurrence can occur.
authors.affiliation: a Department of Ophthalmology & Visual Sciences, Vanderbilt University School of Medicine, Vanderbilt Eye Institute , Vanderbilt University Medical Center , Nashville , TN , USA.
authors.forename: Mark P
authors.initials: MP
authors.lastname: Breazzano
authors.affiliation: b Department of Pathology, Microbiology, and Immunology, Vanderbilt University School of Medicine , Vanderbilt University Medical Center , Nashville , TN , USA.|c Department of Otolaryngology, Vanderbilt University School of Medicine , Vanderbilt University Medical Center , Nashville , TN , USA.
authors.forename: James S
authors.initials: JS
authors.lastname: Lewis
authors.affiliation: d Department of Neurological Surgery, Vanderbilt University School of Medicine , Vanderbilt University Medical Center , Nashville , TN , USA.
authors.forename: Lola B
authors.initials: LB
authors.lastname: Chambless
authors.affiliation: c Department of Otolaryngology, Vanderbilt University School of Medicine , Vanderbilt University Medical Center , Nashville , TN , USA.
authors.forename: Sarah L
authors.initials: SL
authors.lastname: Rohde
authors.affiliation: a Department of Ophthalmology & Visual Sciences, Vanderbilt University School of Medicine, Vanderbilt Eye Institute , Vanderbilt University Medical Center , Nashville , TN , USA.
authors.forename: Rachel K
authors.initials: RK
authors.lastname: Sobel
mesh_terms: D000368:Aged; D018304:Esthesioneuroblastoma, Olfactory / Q000175:diagnosis*; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology*; D008297:Male; D009296:Nasal Cavity / Q000473:pathology*; D009333:Neck; D009364:Neoplasm Recurrence, Local; D009669:Nose Neoplasms / Q000175:diagnosis*; D009918:Orbital Neoplasms / Q000175:diagnosis*; D014057:Tomography, X-Ray Computed
keywords: Delayed recurrence; Kadish staging; exenteration; olfactory neuroblastoma; orbital recurrence