title: Medicaid's Impact on Chronic Disease Biomarkers: A Cohort Study of Community Health Center Patients.
abstract: BACKGROUND
  Understanding the impact of health insurance is critical, particularly in the era of Affordable Care Act Medicaid expansion. The electronic health record (EHR) provides new opportunities to quantify health outcomes.
  
  
  OBJECTIVE
  To assess changes in biomarkers of chronic disease among community health center (CHC) patients who gained Medicaid coverage with the Oregon Medicaid expansion (2008-2011).
  
  
  METHODS
  Prospective cohort. Patients were followed for 24 months, and rate of mean biomarker change was calculated. Time to a controlled follow-up measurement was compared using Cox regression models.
  
  
  METHODS
  Using EHR data from OCHIN (a non-profit network of CHCs) linked to state Medicaid data, we identified three cohorts of patients with uncontrolled chronic conditions (diabetes, hypertension, and hyperlipidemia). Within these cohorts, we included patients who gained Medicaid coverage along with a propensity score-matched comparison group who remained uninsured (diabetes n = 608; hypertension n = 1244; hyperlipidemia n = 546).
  
  
  METHODS
  Hemoglobin A1c (HbA1c) for the diabetes cohort, systolic and diastolic blood pressure (SBP and DBP, respectively) for the hypertension cohort, and low-density lipoprotein (LDL) for the hyperlipidemia cohort.
  
  
  RESULTS
  All cohorts improved over time. Compared to matched uninsured patients, adults in the diabetes and hypertension cohorts who gained Medicaid coverage were significantly more likely to have a follow-up controlled measurement (hazard ratio [HR] =1.26, p = 0.020; HR = 1.35, p < 0.001, respectively). No significant difference was observed in the hyperlipidemia cohort (HR = 1.09, p = 0.392).
  
  
  CONCLUSIONS
  OCHIN patients with uncontrolled chronic conditions experienced objective health improvements over time. In two of three chronic disease cohorts, those who gained Medicaid coverage were more likely to achieve a controlled measurement than those who remained uninsured. These findings demonstrate the effective care provided by CHCs and the importance of health insurance coverage within a usual source of care setting.
  
  
  BACKGROUND
  NCT02355132 [ https://clinicaltrials.gov/ct2/show/NCT02355132 ].
authors.affiliation: Oregon Health & Science University, Portland, OR, USA.|OCHIN, Inc., Portland, OR, USA.
authors.forename: Brigit
authors.initials: B
authors.lastname: Hatch
authors.affiliation: Oregon Health & Science University, Portland, OR, USA.
authors.forename: Miguel
authors.initials: M
authors.lastname: Marino
authors.affiliation: Oregon Health & Science University, Portland, OR, USA.
authors.forename: Marie
authors.initials: M
authors.lastname: Killerby
authors.affiliation: Oregon Health & Science University, Portland, OR, USA. angierh@ohsu.edu.
authors.forename: Heather
authors.initials: H
authors.lastname: Angier
authors.affiliation: OCHIN, Inc., Portland, OR, USA.
authors.forename: Megan
authors.initials: M
authors.lastname: Hoopes
authors.affiliation: Oregon Health & Science University, Portland, OR, USA.
authors.forename: Steffani R
authors.initials: SR
authors.lastname: Bailey
authors.affiliation: Oregon Health & Science University, Portland, OR, USA.
authors.forename: John
authors.initials: J
authors.lastname: Heintzman
authors.affiliation: Oregon Health & Science University, Portland, OR, USA.
authors.forename: Jean P
authors.initials: JP
authors.lastname: O'Malley
authors.affiliation: Oregon Health & Science University, Portland, OR, USA.|OCHIN, Inc., Portland, OR, USA.
authors.forename: Jennifer E
authors.initials: JE
authors.lastname: DeVoe
mesh_terms: D000328:Adult; D015415:Biomarkers / Q000032:analysis*; D002908:Chronic Disease / Q000191:economics*; D003151:Community Health Centers; D005260:Female; D005500:Follow-Up Studies; D006297:Health Services Accessibility / Q000639:trends*; D006801:Humans; D007348:Insurance, Health / Q000191:economics*; D008297:Male; D008484:Medicaid / Q000458:organization & administration*; D008875:Middle Aged; D058991:Patient Protection and Affordable Care Act; D011446:Prospective Studies; D014481:United States; D055815:Young Adult
chemical_list: D015415:Biomarkers
keywords: Medicaid; access to healthcare; biomarkers