title: A 64-Year-Old Woman with Chest Pain, Limb Weakness, and Endometrial Cancer.
abstract: Necrotizing autoimmune myopathy (NAM) is a rare subgroup of idiopathic inflammatory myopathies (IIM). This pathology usually affects proximal limb muscles and in some cases the myocardium. Patients usually display proximal limb weakness. Muscular biopsy is required to confirm the diagnosis. We report the case of a 64-year-old woman with an atypical first presentation of NAM, manifested by chest pain in the context of metastatic endometrial cancer. The diagnosis of NAM was however made when she returned a second time with proximal limb weakness. A treatment with prednisone was then initiated, to which rituximab was rapidly associated, beside a specific chemotherapy.
authors.affiliation: Internal Medicine Department, Hôpital de la Tour, Geneva, Switzerland.
authors.forename: Simon
authors.identifier: 0000-0001-7908-112X
authors.initials: S
authors.lastname: Ponthus
authors.affiliation: Internal Medicine Department, Hôpital de la Tour, Geneva, Switzerland.
authors.forename: Omar
authors.initials: O
authors.lastname: Kherad
authors.affiliation: Internal Medicine Department, Hôpital de la Tour, Geneva, Switzerland.
authors.forename: Nicole
authors.initials: N
authors.lastname: Petriccioli
authors.affiliation: Department of Pathology, Geneva University Hospitals, Geneva, Switzerland.
authors.forename: Johannes Alexander
authors.initials: JA
authors.lastname: Lobrinus
authors.affiliation: Department of Rheumatology, Geneva University Hospitals, Geneva, Switzerland.
authors.forename: Pierre-André A
authors.initials: PA
authors.lastname: Guerne