title: Lateral ridge augmentation with Bio-Oss alone or Bio-Oss mixed with particulate autogenous bone graft: a systematic review.
abstract: The objective of this systematic review was to test the hypothesis of no difference in implant treatment outcomes when using Bio-Oss alone or Bio-Oss mixed with particulate autogenous bone grafts for lateral ridge augmentation. A search of the MEDLINE, Cochrane Library, and Embase databases in combination with a hand-search of relevant journals was conducted. Human studies published in English from 1 January 1990 to 1 May 2016 were included. The search provided 337 titles and six studies fulfilled the inclusion criteria. Considerable variation prevented a meta-analysis from being performed. The two treatment modalities have never been compared within the same study. Non-comparative studies demonstrated a 3-year implant survival of 96% with 50% Bio-Oss mixed with 50% autogenous bone graft. Moreover, Bio-Oss alone or Bio-Oss mixed with autogenous bone graft seems to increase the amount of newly formed bone as well as the width of the alveolar process. Within the limitations of this systematic review, lateral ridge augmentation with Bio-Oss alone or in combination with autogenous bone graft seems to induce newly formed bone and increase the width of the alveolar process, with high short-term implant survival. However, long-term studies comparing the two treatment modalities are needed before final conclusions can be drawn.
authors.affiliation: Department of Oral and Maxillofacial Surgery, Aalborg University Hospital, Aalborg, Denmark. Electronic address: h.aludden@rn.dk.
authors.forename: H C
authors.initials: HC
authors.lastname: Aludden
authors.affiliation: Department of Oral and Maxillofacial Surgery, Public Health Service, Gävle, Sweden.
authors.forename: A
authors.initials: A
authors.lastname: Mordenfeld
authors.affiliation: Department of Oral and Maxillofacial Surgery, Public Health Service, Gävle, Sweden.
authors.forename: M
authors.initials: M
authors.lastname: Hallman
authors.affiliation: Department of Biomaterials, BIOMATCELL VINN Excellence Centre, Institute for Surgical Science, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; Department of Oral and Maxillofacial Surgery, NU-Hospital Organization, Trollhättan, Sweden.
authors.forename: C
authors.initials: C
authors.lastname: Dahlin
authors.affiliation: Department of Oral and Maxillofacial Surgery, Aalborg University Hospital, Aalborg, Denmark.
authors.forename: T
authors.initials: T
authors.lastname: Jensen
mesh_terms: D000540:Alveolar Ridge Augmentation / Q000379:methods*; D001861:Bone Regeneration / Q000502:physiology; D018786:Bone Substitutes / Q000627:therapeutic use*; D016025:Bone Transplantation / Q000379:methods*; D015921:Dental Implants; D006085:Graft Survival; D006801:Humans; D008903:Minerals / Q000627:therapeutic use*; D059546:Sinus Floor Augmentation / Q000379:methods
chemical_list: C077540:Bio-Oss; D018786:Bone Substitutes; D015921:Dental Implants; D008903:Minerals
keywords: Bio-Oss; alveolar ridge augmentation; bone substitute; dental implants; systematic review