title: Comparison of micro-CT and cone beam CT on the feasibility of assessing trabecular structures in mandibular condyle.
abstract: OBJECTIVE
  To evaluate the accuracy of CBCT in assessing trabecular structures.
  
  
  METHODS
  Two human mandibles were scanned by micro-CT (Skyscan 1173 high-energy spiral scan micro-CT; Skyscan NV, Kontich, Belgium) and CBCT (3D Accuitomo 170; Morita, Japan). The CBCT images were reconstructed with 0.5 and 1 mm thicknesses. The condylar images were selected for registration. A parallel algorithm for histogram computation was introduced to perform the registration. A mutual information (MI) value was used to evaluate the match between the images obtained from micro-CT and CBCT.
  
  
  RESULTS
  In comparison with the micro-CT image for the two samples, the CBCT image with 0.5 mm thickness has a MI value of 0.873 and 0.903 while that with 1.0 mm thickness has a MI value of 0.741 and 0.752. The CBCT images with 0.5 mm thickness were better matched with micro-CT images.
  
  
  CONCLUSIONS
  CBCT shows comparable accuracy with high-resolution micro-CT in assessing trabecular structures. CBCT can be a feasible tool to evaluate osseous changes of jaw bones.
authors.affiliation: 1 School and Hospital of Stomatology, Peking University, Beijing, China.|2 School of Stomatology, Dalian Medical University, Dalian, Liaoning, China.
authors.forename: Xin
authors.initials: X
authors.lastname: Liang
authors.affiliation: 1 School and Hospital of Stomatology, Peking University, Beijing, China.
authors.forename: Zuyan
authors.initials: Z
authors.lastname: Zhang
authors.affiliation: 3 Department of Engineering Physics, Tsinghua University, Beijing, China.
authors.forename: Jianping
authors.initials: J
authors.lastname: Gu
authors.affiliation: 1 School and Hospital of Stomatology, Peking University, Beijing, China.
authors.forename: Zhihui
authors.initials: Z
authors.lastname: Wang
authors.affiliation: 4 Oral Imaging Center, Department of Oral Health Sciences, KU Leuven, Leuven, Belgium.
authors.forename: Bart
authors.initials: B
authors.lastname: Vandenberghe
authors.affiliation: 4 Oral Imaging Center, Department of Oral Health Sciences, KU Leuven, Leuven, Belgium.
authors.forename: Reinhilde
authors.initials: R
authors.lastname: Jacobs
authors.affiliation: 5 Oral and Maxillofacial Radiology, School of Dentistry, Temple University, Philadelphia, PA, USA.
authors.forename: Jie
authors.initials: J
authors.lastname: Yang
authors.affiliation: 2 School of Stomatology, Dalian Medical University, Dalian, Liaoning, China.
authors.forename: Guowu
authors.initials: G
authors.lastname: Ma
authors.affiliation: 6 Department of Computer and Information Sciences, Temple University, Philadelphia, PA, USA.
authors.forename: Haibin
authors.initials: H
authors.lastname: Ling
authors.affiliation: 1 School and Hospital of Stomatology, Peking University, Beijing, China.
authors.forename: Xuchen
authors.initials: X
authors.lastname: Ma
mesh_terms: D000465:Algorithms; D002102:Cadaver; D054893:Cone-Beam Computed Tomography / Q000379:methods*; D005240:Feasibility Studies; D006801:Humans; D008335:Mandibular Condyle / Q000000981:diagnostic imaging*; D011857:Radiographic Image Interpretation, Computer-Assisted; D055114:X-Ray Microtomography / Q000379:methods*
keywords: CBCT; micro-CT; trabecular structure