title: Synthesis of Sugar-Boronic Acid Derivatives: A Class of Potential Agents for Boron Neutron Capture Therapy.
abstract: To date, sugar analogues that contain boronic acids as substitutes for hydroxyl groups are a class of compounds nearly unknown in the literature. The challenging synthesis of two sugar-boronic acid analogues is described, and data are retrieved on their solution behavior, stability, and toxicity. As these compounds were expected to mimic the behavior of carbohydrates, they were tested in regards to their future development as potential boron neutron capture therapy agents.
authors.affiliation: Department of Pharmaceutical Sciences, Università del Piemonte Orientale , Largo Donegani 2, 28100 Novara, Italy.
authors.forename: Daniela
authors.initials: D
authors.lastname: Imperio
authors.affiliation: Department of Pharmaceutical Sciences, Università del Piemonte Orientale , Largo Donegani 2, 28100 Novara, Italy.
authors.forename: Erika
authors.initials: E
authors.lastname: Del Grosso
authors.affiliation: Department of Pharmaceutical Sciences, Università del Piemonte Orientale , Largo Donegani 2, 28100 Novara, Italy.
authors.forename: Silvia
authors.initials: S
authors.lastname: Fallarini
authors.affiliation: Department of Pharmaceutical Sciences, Università del Piemonte Orientale , Largo Donegani 2, 28100 Novara, Italy.
authors.forename: Grazia
authors.initials: G
authors.lastname: Lombardi
authors.affiliation: Department of Pharmaceutical Sciences, Università del Piemonte Orientale , Largo Donegani 2, 28100 Novara, Italy.
authors.forename: Luigi
authors.identifier: 0000-0002-0785-0409
authors.initials: L
authors.lastname: Panza