title: Adult B-Cell Acute Lymphoblastic Leukemia Dominated by Osteolytic Bone Involvement on CT But Less Impressive PET on FDG PET/CT Images.
abstract: A 47-year-old man presented with abdominal pain, vomiting, and bone pain. Laboratory findings revealed severe hypercalcemia, anemia, and renal insufficiency with decreased serum parathyroid hormone. FDG PET/CT was performed for characteristics suggestive of multiple myeloma and other occult malignancy. The images revealed widespread osteolytic lesions with only 1 focus of definite abnormal FDG uptake. B-cell acute lymphoblastic leukemia was confirmed by pathological examination following bone marrow biopsy.
authors.affiliation: From the Departments of *Nuclear Medicine & PET/CT, and †Hematology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
authors.forename: Sijuan
authors.initials: S
authors.lastname: Zou
authors.forename: Yanxia
authors.initials: Y
authors.lastname: Shen
authors.forename: Dongling
authors.initials: D
authors.lastname: Zhu
authors.forename: Donghua
authors.initials: D
authors.lastname: Zhang
authors.forename: Xiaohua
authors.initials: X
authors.lastname: Zhu
mesh_terms: D001692:Biological Transport; D001706:Biopsy; D019788:Fluorodeoxyglucose F18 / Q000378:metabolism; D006801:Humans; D015448:Leukemia, B-Cell / Q000150:complications* / Q000000981:diagnostic imaging* / Q000378:metabolism / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma / Q000150:complications; D010014:Osteolysis / Q000150:complications*; D000072078:Positron Emission Tomography Computed Tomography
chemical_list: D019788:Fluorodeoxyglucose F18