title: 2D Shear Wave Elastography of Liver in Patients with Primary Extrahepatic Portal Vein Obstruction.
abstract: OBJECTIVE
  To evaluate liver stiffness (LS) in patients of primary extrahepatic portal vein obstruction (EHPVO) using 2D shear wave elastography (SWE) and compare it with healthy volunteers.
  
  
  METHODS
  Fifty patients (mean age: 22.4 years) of EHPVO and 25 healthy volunteers were included in the study. Liver function tests and viral markers were done in both groups and endoscopy in EHPVO group, followed by ultrasonography and SWE of liver. Liver elastography was done with patients/volunteers in supine position through right intercostal space. The LS for right lobe of liver was recorded in kilopascals. Three such measurements were taken and the mean of both groups were compared. The variables were also correlated with mean LS using Pearson's correlation coefficient in EHPVO group.
  
  
  RESULTS
  There was no significant difference in the mean LS in patients of EHPVO (5.96 kPa) and healthy volunteers (5.47 kPa) (P= 0.093). There was no significant correlation between LS with duration of symptoms, hematemesis, esophageal varices, total bilirubin, serum alkaline phosphatase and aspartate aminotranferase levels in EHPVO group.
  
  
  CONCLUSIONS
  SWE of liver may be used as a simple additional tool in the diagnosis of patients of EHPVO who show LS values similar to normal liver.
authors.affiliation: Department of Radiodiagnosis, All India Institute of Medical Sciences, New Delhi 110029, India.
authors.forename: Kumble S
authors.initials: KS
authors.lastname: Madhusudhan
authors.affiliation: Department of Radiodiagnosis, All India Institute of Medical Sciences, New Delhi 110029, India.
authors.forename: Raju
authors.initials: R
authors.lastname: Sharma
authors.affiliation: Department of Gastrointestinal Surgery, All India Institute of Medical Sciences, New Delhi 110029, India.
authors.forename: Ragini
authors.initials: R
authors.lastname: Kilambi
authors.affiliation: Department of Radiodiagnosis, All India Institute of Medical Sciences, New Delhi 110029, India.
authors.forename: Sudhin
authors.initials: S
authors.lastname: Shylendran
authors.affiliation: Department of Gastroenterology, All India Institute of Medical Sciences, New Delhi 110029, India.
authors.lastname: Shalimar
authors.affiliation: Department of Gastrointestinal Surgery, All India Institute of Medical Sciences, New Delhi 110029, India.
authors.forename: Peush
authors.initials: P
authors.lastname: Sahni
authors.affiliation: Department of Radiodiagnosis, All India Institute of Medical Sciences, New Delhi 110029, India.
authors.forename: Arun K
authors.initials: AK
authors.lastname: Gupta
keywords: Cirrhosis; Elastography; Extrahepatic portal vein obstruction; Liver stiffness; Shear wave elastography