title: [Autophagy in the cardiovascular system].
abstract: Cardiovascular diseases are the leading cause of mortality worldwide. Studies regarding the role of autophagy in cardiac and vascular tissues have opened new therapeutic avenues to treat cardiovascular disorders. Altogether, these studies point out that autophagic activity needs to be maintained at an optimal level to preserve cardiovascular function. Reaching this goal constitutes a challenge for future efficient therapeutic strategies. The present review therefore highlights recent advances in the understanding of the role of autophagy in cardiovascular pathologies.
authors.affiliation: Inserm, U970, Paris cardiovascular research center - PARCC, 56, rue Leblanc, 75015 Paris, France - Université Paris Descartes, Sorbonne Paris Cité, UMR-S 970, Paris, France - Université Denis Diderot-Paris 7, Sorbonne Paris Cité, 75018 Paris, France.
authors.forename: Marouane
authors.initials: M
authors.lastname: Kheloufi
authors.affiliation: Inserm, U970, Paris cardiovascular research center - PARCC, 56, rue Leblanc, 75015 Paris, France - Université Paris Descartes, Sorbonne Paris Cité, UMR-S 970, Paris, France - Service d'hépatologie, DHU unity, Hôpital Beaujon, Assistance Publique-Hôpitaux de Paris, Clichy, France.
authors.forename: Pierre-Emmanuel
authors.initials: PE
authors.lastname: Rautou
authors.affiliation: Inserm, U970, Paris cardiovascular research center - PARCC, 56, rue Leblanc, 75015 Paris, France - Université Paris Descartes, Sorbonne Paris Cité, UMR-S 970, Paris, France.
authors.forename: Chantal M
authors.initials: CM
authors.lastname: Boulanger
mesh_terms: D000818:Animals; D001343:Autophagy / Q000502:physiology*; D002318:Cardiovascular Diseases / Q000473:pathology / Q000503:physiopathology; D002320:Cardiovascular Physiological Phenomena; D002319:Cardiovascular System / Q000473:pathology / Q000503:physiopathology; D006801:Humans; D032383:Myocytes, Cardiac / Q000473:pathology / Q000502:physiology