title: The Antibacterial Resistance Leadership Group: Progress Report and Work in Progress.
abstract: The Antibacterial Resistance Leadership Group (ARLG), with funding from the National Institute of Allergy and Infectious Diseases of the National Institutes of Health, was created in June 2013. Its mission is to develop, prioritize, and implement a clinical research agenda that addresses the public health threat of antibacterial resistance. This article reports on the progress that the ARLG has made to date in fulfilling its mission. Since inception, the ARLG has received and reviewed >70 study proposals, initiated >30 studies, executed >300 agreements, included data from >7000 subjects, published >45 manuscripts, and provided opportunities for 26 mentees. Despite this substantial progress, there remains significant work to be accomplished. This article also describes the considerable challenges that lie ahead.
authors.affiliation: University of California, San Francisco, San Francisco General Hospital.
authors.forename: Henry F Chip
authors.initials: HF
authors.lastname: Chambers
authors.affiliation: Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina.
authors.forename: Heather R
authors.initials: HR
authors.lastname: Cross
authors.affiliation: Center for Biostatistics in AIDS Research and Department of Biostatistics, Harvard University, Boston, Massachusetts.
authors.forename: Scott R
authors.initials: SR
authors.lastname: Evans
authors.affiliation: Public Health Research Institute Tuberculosis Center, New Jersey Medical School-Rutgers University, Newark; and.
authors.forename: Barry N
authors.initials: BN
authors.lastname: Kreiswirth
authors.affiliation: Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina.|Division of Infectious Diseases, Department of Medicine, Duke University Medical Center, Durham, North Carolina.
authors.forename: Vance G
authors.initials: VG
authors.lastname: Fowler
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology / Q000627:therapeutic use; D035843:Biomedical Research / Q000458:organization & administration*; D024881:Drug Resistance, Bacterial; D006801:Humans; D007857:Leadership; D058028:Research Report; D014837:Voluntary Health Agencies
chemical_list: D000900:Anti-Bacterial Agents
keywords: antibacterial resistance; clinical trials.; diagnostics; network; stewardship