title: Synthetic Access Toward Cycloastragenol Glycosides.
abstract: The first efficient synthetic approach toward four types of the cycloartane glycosides, the cycloastragenol 25-O; 3-O; 3,6-O-bis; and 3,25-O-bisglycoside, have been established, which featured the PPY-mediated, concentration-controlled acetylation and Au(I)-catalyzed Yu glycosylation. Through the synthetic investigation, the reactivity sequence of the four OHs in cycloastragenol was fixed for the first time and a detour strategy for the highly efficient removal of bulky pivaloyl protecting groups was discovered.
authors.affiliation: The National Research Centre for Carbohydrate Synthesis, Jiangxi Normal University , 99 Ziyang Avenue, Nanchang 330022, China.
authors.forename: Ting
authors.initials: T
authors.lastname: Liu
authors.affiliation: The National Research Centre for Carbohydrate Synthesis, Jiangxi Normal University , 99 Ziyang Avenue, Nanchang 330022, China.
authors.forename: Jin-Xi
authors.initials: JX
authors.lastname: Liao
authors.affiliation: The National Research Centre for Carbohydrate Synthesis, Jiangxi Normal University , 99 Ziyang Avenue, Nanchang 330022, China.
authors.forename: Yang
authors.initials: Y
authors.lastname: Hu
authors.affiliation: The National Research Centre for Carbohydrate Synthesis, Jiangxi Normal University , 99 Ziyang Avenue, Nanchang 330022, China.
authors.forename: Yuan-Hong
authors.initials: YH
authors.lastname: Tu
authors.affiliation: The National Research Centre for Carbohydrate Synthesis, Jiangxi Normal University , 99 Ziyang Avenue, Nanchang 330022, China.
authors.forename: Jian-Song
authors.identifier: 0000-0001-6413-943X
authors.initials: JS
authors.lastname: Sun