title: Multiparticle Brownian dynamics simulation of experimental kinetics of cytochrome bf oxidation and photosystem I reduction by plastocyanin.
abstract: A model of electron transport from cytochrome f to photosystem I mediated by plastocyanin was designed on the basis of the multiparticle Brownian dynamics method. The model combines events which occur over a wide time range, including protein diffusion along the thylakoid membrane, long-distance interactions between proteins, formation of a multiprotein complex, electron transfer within a complex and complex dissociation. Results of the modeling were compared with the experimental kinetics measured in chloroplast thylakoids. Computer simulation demonstrated that the complex interior of the photosynthetic membrane, electrostatic interactions and Brownian diffusion provide physical conditions for the directed electron flow along the photosynthetic electron transport chain.
authors.affiliation: Biology Faculty, Lomonosov Moscow State University, Moscow, 119992, Russia.
authors.forename: Ilya B
authors.initials: IB
authors.lastname: Kovalenko
authors.affiliation: Physical Faculty, Lomonosov Moscow State University, Moscow, 119992, Russia.
authors.forename: Olga S
authors.initials: OS
authors.lastname: Knyazeva
authors.affiliation: Biology Faculty, Lomonosov Moscow State University, Moscow, 119992, Russia.
authors.forename: Taras K
authors.identifier: http://orcid.org/0000-0002-9690-8034
authors.initials: TK
authors.lastname: Antal
authors.affiliation: Biology Faculty, Lomonosov Moscow State University, Moscow, 119992, Russia.
authors.forename: Vladimir Y
authors.initials: VY
authors.lastname: Ponomarev
authors.affiliation: Biology Faculty, Lomonosov Moscow State University, Moscow, 119992, Russia.
authors.forename: Galina Yu
authors.initials: GY
authors.lastname: Riznichenko
authors.affiliation: Biology Faculty, Lomonosov Moscow State University, Moscow, 119992, Russia.
authors.forename: Andrei B
authors.initials: AB
authors.lastname: Rubin
mesh_terms: D002734:Chlorophyll / Q000378:metabolism; D003198:Computer Simulation; D045346:Cytochrome b6f Complex / Q000378:metabolism*; D004579:Electron Transport; D007700:Kinetics; D008954:Models, Biological; D008958:Models, Molecular; D010084:Oxidation-Reduction; D045331:Photosystem I Protein Complex / Q000378:metabolism*; D010970:Plastocyanin / Q000378:metabolism*; D055672:Static Electricity; D013997:Time Factors
chemical_list: D045331:Photosystem I Protein Complex; D002734:Chlorophyll; C001785:chlorophyll P 700; D010970:Plastocyanin; D045346:Cytochrome b6f Complex