title: The HIV oligonucleotide database (HIVoligoDB).
abstract: The human immunodeficiency virus (HIV) is associated with one of the most widespread infectious disease, the acquired immunodeficiency syndrome (AIDS). The development of antiretroviral drugs and methods for virus detection requires a comprehensive analysis of the HIV genomic diversity, particularly in the binding sites of oligonucleotides. Here, we describe a versatile online database (HIVoligoDB) with oligonucleotides selected for the diagnosis of HIV and treatment of AIDS. Currently, the database provides an interface for visualization, analysis and download of 380 HIV-1 and 65 HIV-2 oligonucleotides annotated according to curated reference genomes. The database also allows the selection of the most conserved HIV genomic regions for the development of molecular diagnostic assays and sequence-based candidate therapeutics.
  
  
  
  http://portugene.com/HIVoligoDB.
authors.affiliation: Interdisciplinary Centre of Marine and Environmental Research (CIIMAR), University of Porto, Terminal de Cruzeiros do Porto de Leix?Av. General Norton de Matos s/n 4450-208 Porto.
authors.forename: João
authors.initials: J
authors.lastname: Carneiro
authors.affiliation: Interdisciplinary Centre of Marine and Environmental Research (CIIMAR), University of Porto, Terminal de Cruzeiros do Porto de Leix?Av. General Norton de Matos s/n 4450-208 Porto.
authors.forename: Adriana
authors.initials: A
authors.lastname: Resende
authors.forename: Filipe
authors.initials: F
authors.lastname: Pereira
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000235:genetics*; D016679:Genome, Viral; D015497:HIV-1 / Q000235:genetics*; D015498:HIV-2 / Q000235:genetics*; D006801:Humans; D009841:Oligonucleotides / Q000235:genetics*
chemical_list: D009841:Oligonucleotides