title: Metal-Free [2 + 1 + 2]-Cycloaddition of Tosylhydrazones with Hexahydro-1,3,5-triazines To Form Imidazolidines.
abstract: A novel protocol toward imidazolidines has been accomplished using tosylhydrazones and hexahydro-1,3,5-triazines as the substrates under metal-free reaction conditions. Importantly, the role of LiOtBu has been confirmed not only to release the diazo but also to promote the cycloaddition. Further mechanistic investigations reveal that the reaction proceeds through a stepwise [2 + 1 + 2] process.
authors.affiliation: Jiangsu Key Laboratory of Advanced Catalytic Materials & Technology and School of Pharmaceutical Engineering & Life Science, Changzhou University , Changzhou 213164, P. R. China.
authors.forename: Pei
authors.initials: P
authors.lastname: Liu
authors.affiliation: Jiangsu Key Laboratory of Advanced Catalytic Materials & Technology and School of Pharmaceutical Engineering & Life Science, Changzhou University , Changzhou 213164, P. R. China.
authors.forename: Guangyang
authors.initials: G
authors.lastname: Xu
authors.affiliation: Jiangsu Key Laboratory of Advanced Catalytic Materials & Technology and School of Pharmaceutical Engineering & Life Science, Changzhou University , Changzhou 213164, P. R. China.
authors.forename: Jiangtao
authors.identifier: 0000-0003-2516-3466
authors.initials: J
authors.lastname: Sun