title: Prevention and treatment of peritoneal adhesions in patients affected by vascular diseases following surgery: a review of the literature.
abstract: Intra-abdominal adhesions are the most frequently occurring postoperative complication following abdomino-pelvic surgery. Abdominal and pelvic surgery can lead to peritoneal adhesion formation causing infertility, chronic pelvic pain, and intestinal obstruction. Laparoscopy today is considered the gold standard of care in the treatment of several abdominal pathologies as well as in a wide range of vascular diseases. Laparoscopy has several advantages in comparison to open surgery. These include rapid recovery times, shorter hospitalisation, reduced postoperative pain, as well as cosmetic benefits. The technological improvements in this particular surgical field along with the development of modern techniques and the acquisition of specific laparoscopic skills have allowed for its wider utilization in operations with fully intracorporeal anastomoses. Postoperative adhesions are caused by aberrant peritoneal healing and are the leading cause of postoperative bowel obstruction. The use of anti-adherence barriers is currently being advocated for their prevention. The outcome of the investigation showed adhesion formation inhibition without direct detrimental effects on anastomotic healing. Poor anasto-motic healing can provoke adhesions even in the presence of anti-adhesion barriers. This review gives a short overview on the current evidence on the pathophysiology and prevention of peritoneal adhesions.
authors.affiliation: Department of Clinical Medicine and Surgery, University of Naples "Federico II", Naples, Italy . Via Sergio Pansini, 80131 Naples, Italy.
authors.forename: Aldo
authors.initials: A
authors.lastname: Rocca
authors.affiliation: Department of Clinical Medicine and Surgery, University of Naples Federico II, Italy.
authors.forename: Giovanni
authors.initials: G
authors.lastname: Aprea
authors.affiliation: Unit of Surgery, A. Cardarelli Hospital, Campo-basso, Italy.
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Surfaro
authors.affiliation: Department of Clinical Medicine and Surgery, University of Naples Federico II, Italy.
authors.forename: Maurizio
authors.initials: M
authors.lastname: Amato
authors.affiliation: Unit of Hepatobiliary Surgery and Liver Transplant Center, Department of Gastroenterology and Transplantation, "A. Cardarelli" Hospital, Naples, Italy.
authors.forename: Antonio
authors.initials: A
authors.lastname: Giuliani
authors.affiliation: Department of Medicine and Health Sciences "Vincenzo Tiberio", University of Molise, Campobasso, Italy.
authors.forename: Marianna
authors.initials: M
authors.lastname: Paccone
authors.affiliation: Department of Translational Medical Sciences, University of Naples "Federico II", Naples, Italy.
authors.forename: Andrea
authors.initials: A
authors.lastname: Salzano
authors.affiliation: Santa Maria delle Grazie Hospital, Pathology Unit, Pozzuoli, Naples, Italy.
authors.forename: Anna
authors.initials: A
authors.lastname: Russo
authors.affiliation: Department of Sport Sciences and Wellness, University of Naples "Parthenope", Naples, Italy.
authors.forename: Domenico
authors.initials: D
authors.lastname: Tafuri
authors.affiliation: Department of Clinical Medicine and Surgery, University of Naples Federico II, Italy.
authors.forename: Bruno
authors.initials: B
authors.lastname: Amato
keywords: Anti-adhesive barriers; Laparoscopy; Pain; Peritoneal adhesions; Vascular Surgery