title: Lamotrigine-related pseudolymphoma presenting as cervical lymphadenopathy.
abstract: Immune-mediated drug reactions are a potentially life-threatening complication of antiseizure medications. Drug hypersensitivity syndrome (DHS) is the best recognised of these, presenting with fever, eosinophilia, rash and internal organ involvement. Isolated lymphadenopathy is a less recognized immune-mediated reaction to antiseizure drugs such as lamotrigine. We describe the case of a 24-year-old woman who developed lamotrigine-related bilateral cervical lymphadenopathy (pseudolymphoma) fifteen months following therapy initiation. This is the second such case reported in the medical literature.
authors.affiliation: Department of Neurology, Auckland City Hospital, 2 Park Road, Auckland, New Zealand.
authors.forename: Eoin
authors.initials: E
authors.lastname: Mulroy
authors.affiliation: Department of Neurology, Auckland City Hospital, 2 Park Road, Auckland, New Zealand.
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Walker
keywords: Anticonvulsants; Drug hypersensitivity syndrome; Eosinophilia; Pseudolymphoma