title: Microbial glycoproteomics.
abstract: Mass spectrometry-based "-omics" technologies are important tools for global and detailed mapping of post-translational modifications. Protein glycosylation is an abundant and important post translational modification widespread throughout all domains of life. Characterization of glycoproteins, including identification of glycan structure and components, their attachment sites and protein carriers, remains challenging. However, recent advances in glycoproteomics, a subbranch that studies and categorizes protein glycosylations, have greatly expanded the known protein glycosylation space and research in this area is rapidly accelerating. Here, we review recent developments in glycoproteomic technologies with a special focus on microbial protein glycosylation.
authors.affiliation: Copenhagen Center for Glycomics, Departments of Cellular and Molecular Medicine, Faculty of Health Sciences, University of Copenhagen, Blegdamsvej 3, DK-2200 Copenhagen N, Denmark. Electronic address: halim@sund.ku.dk.
authors.forename: Adnan
authors.initials: A
authors.lastname: Halim
authors.affiliation: Center for Integrative Microbial Evolution, The Mass Spectrometry and Proteomics Unit, Department of Biosciences, University of Oslo, Blindernveien 31, 0371 Oslo, Norway. Electronic address: j.h.anonsen@ibv.uio.no.
authors.forename: Jan Haug
authors.initials: JH
authors.lastname: Anonsen
mesh_terms: D000818:Animals; D006023:Glycoproteins / Q000737:chemistry / Q000378:metabolism*; D006801:Humans; D013058:Mass Spectrometry; D008829:Microbiology; D040901:Proteomics / Q000379:methods*
chemical_list: D006023:Glycoproteins