title: Short-Term Left Ventricular Remodeling After Revascularization in Subacute Total and Subtotal Occlusion With the Infarct-Related Left Anterior Descending Artery.
abstract: BACKGROUND
  Large randomized studies revealed that percutaneous coronary intervention has no clinical benefit in patients with total occlusion. The purpose of this study is to evaluate left ventricular remodelling after PCI for total and subtotal infarct-related left anterior desending artery in stable patients who have not received trombolytic theraphy.
  
  
  METHODS
  Sixty stable patients with subacute anterior myocardial infarction who have total or subtotal occlusion in the infarct-related left anterior descending artery were enrolled the study (20 patient in the total-medical group, 20 patient in the total-PCI group and 20 patient in the subtotal-PCI group). All patients' left ventricular diameters, volumes and ejection fractions measured at admission and after a month.
  
  
  RESULTS
  The necrotic segment number in scintigraphy were similar in three groups. In the total-PCI group, there were significant increases in left ventricular diastolic diameter, left ventricular end-diastolic volume and left ventricular end-systolic volume at first month. A borderline significant increase was observed in LVEDV in the total-medical group at first month. No significant difference was seen in all echocardiographic parameters in the subtotal-PCI group at a month after discharge. The percentage of increase in LVEDV was significantly higher and the percentage of increase in LVESV was borderline significantly higher in the total-PCI group than the other groups.
  
  
  CONCLUSIONS
  In stable patients, PCI for total occlusion in the subacute phase of anterior MI causes an increase in LV remodeling. Nevertheless PCI for subtotal occlusion in the subacute phase of anterior MI may prevent LV remodeling.
authors.affiliation: Department of Cardiology, Elazıg Education and Research Hospital, Elazig, Turkey.
authors.forename: Ahmet
authors.initials: A
authors.lastname: Celik
authors.affiliation: Department of Cardiology, Erciyes University Medical Faculty, Kayseri, Turkey.
authors.forename: Nihat
authors.initials: N
authors.lastname: Kalay
authors.affiliation: Department of Cardiology, Elazıg Education and Research Hospital, Elazig, Turkey.
authors.forename: Hasan
authors.initials: H
authors.lastname: Korkmaz
authors.affiliation: Department of Cardiology, Erciyes University Medical Faculty, Kayseri, Turkey.
authors.forename: Orhan
authors.initials: O
authors.lastname: Dogdu
authors.affiliation: Department of Cardiology, Erciyes University Medical Faculty, Kayseri, Turkey.
authors.forename: Omer
authors.initials: O
authors.lastname: Sahin
authors.affiliation: Department of Cardiology, Erciyes University Medical Faculty, Kayseri, Turkey.
authors.forename: Deniz
authors.initials: D
authors.lastname: Elcik
authors.affiliation: Department of Nuclear Medicine, Erciyes University Medical Faculty, Kayseri, Turkey.
authors.forename: Seyhan
authors.initials: S
authors.lastname: Karacavus
authors.affiliation: Department of Cardiology, Erciyes University Medical Faculty, Kayseri, Turkey.
authors.forename: Ali
authors.initials: A
authors.lastname: Dogan
authors.affiliation: Department of Cardiology, Erciyes University Medical Faculty, Kayseri, Turkey.
authors.forename: Tugrul
authors.initials: T
authors.lastname: Inanc
authors.affiliation: Department of Cardiology, Erciyes University Medical Faculty, Kayseri, Turkey.
authors.forename: Ibrahim
authors.initials: I
authors.lastname: Ozdogru
authors.affiliation: Department of Cardiology, Erciyes University Medical Faculty, Kayseri, Turkey.
authors.forename: Abdurrahman
authors.initials: A
authors.lastname: Oguzhan
authors.affiliation: Department of Cardiology, Erciyes University Medical Faculty, Kayseri, Turkey.
authors.forename: Ramazan
authors.initials: R
authors.lastname: Topsakal
keywords: Left anterior descending artery; Left ventricular remodeling; Total and subtotal occlusion