title: Follicular Dendritic Cell Sarcoma.
abstract: Follicular dendritic cell sarcoma is a rare tumor that typically arises within lymph nodes but can also occur extranodally. It is important to have a high index of suspicion, so follicular dendritic cell sarcoma is included in the differential diagnosis of a spindle cell neoplasm in the appropriate clinical and morphologic settings. When included in the differential diagnosis, immunohistochemistry is generally sufficient to substantiate the diagnosis of follicular dendritic cell sarcoma. In this review, we discuss the clinicopathologic features of follicular dendritic cell sarcoma, recent molecular and cytogenetic findings, prognosis, and current approaches to treatment.
authors.forename: Tiffany
authors.initials: T
authors.lastname: Chen
authors.affiliation: From the University of Texas, Southwestern Medical School, Dallas (Ms Chen); and the Department of Pathology, University of Texas, Southwestern Medical Center, Dallas (Dr Gopal).
authors.forename: Purva
authors.initials: P
authors.lastname: Gopal
mesh_terms: D014408:Biomarkers, Tumor / Q000235:genetics / Q000378:metabolism*; D054740:Dendritic Cell Sarcoma, Follicular / Q000175:diagnosis* / Q000235:genetics / Q000378:metabolism*; D003937:Diagnosis, Differential; D020022:Genetic Predisposition to Disease / Q000235:genetics; D006801:Humans; D007150:Immunohistochemistry / Q000379:methods*; D009154:Mutation; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
chemical_list: D014408:Biomarkers, Tumor