title: Urogynecological conditions associated with overactive bladder symptoms in women.
abstract: BACKGROUND
  Overactive bladder symptoms (OAB) affect 9-43% of women and are associated with underlying disorders, including pelvic organ prolapse (POP) and stress urinary incontinence (SUI). The aim of this study is to identify urogynecological conditions associated with OAB symptoms.
  
  
  METHODS
  This prospective, institutional review board-approved study included women referred to a tertiary centre with lower urinary tract symptoms (LUTS). All women completed the self-administered OAB questionnaire (OABSS). Those with an OABSS ≥8, the cutoff, were considered to have OAB symptoms. Patients underwent a history and physical examination (including Baden-Walker prolapse grading and stress test), 24-hour voiding diary, pad test (for urinary incontinence), urinalysis, and uroflow with post-void residual volume. Patients were classified clinically into the following: idiopathic OAB, SUI, POP, bladder outlet obstruction (BOO) neurogenic bladder (NGB), recurrent urinary tract infection (UTI), and miscellaneous.
  
  
  RESULTS
  In total, 148 women met the inclusion criteria with a mean age of 67 years. Only 27% had no comorbid conditions and were considered idiopathic OAB. Associated urogynecological conditions included SUI in 37%, POP in 26%, miscellaneous conditions in 18%, recurrent UTI in 11%, NGB in 9%, and BOO in 8%. Some patients met criteria for more than one category, thus the total is greater than 100%.
  
  
  CONCLUSIONS
  In a tertiary care setting, a significant proportion of women with OAB symptoms have underlying conditions that may cause or contribute to their symptoms. Appropriate evaluation is desirable to enhance our understanding of the relationship of these conditions to the diagnosis, treatment, outcomes, and pathophysiology of OAB.
authors.affiliation: Deptartment of Urology, Weill Medical College of Cornell University, New York, NY, United States.
authors.forename: James C
authors.initials: JC
authors.lastname: Forde
authors.affiliation: Deptartment of Urology, SUNY Downstate Medical School, Brooklyn, NY, United States.
authors.forename: Jonathan L
authors.initials: JL
authors.lastname: Davila
authors.affiliation: Institute for Bladder and Prostate Research, New York, NY, United States.
authors.forename: Brian K
authors.initials: BK
authors.lastname: Marks
authors.affiliation: Deptartment of Urology, SUNY Downstate Medical School, Brooklyn, NY, United States.
authors.forename: Matthew
authors.initials: M
authors.lastname: Epstein
authors.affiliation: Institute for Bladder and Prostate Research, New York, NY, United States.
authors.forename: Johnson F
authors.initials: JF
authors.lastname: Tsui
authors.affiliation: Deptartment of Urology, SUNY Downstate Medical School, Brooklyn, NY, United States; Institute for Bladder and Prostate Research, New York, NY, United States.
authors.forename: Jeffrey P
authors.initials: JP
authors.lastname: Weiss
authors.affiliation: Deptartment of Urology, Weill Medical College of Cornell University, New York, NY, United States; Deptartment of Urology, SUNY Downstate Medical School, Brooklyn, NY, United States; Institute for Bladder and Prostate Research, New York, NY, United States.
authors.forename: Jerry G
authors.initials: JG
authors.lastname: Blaivas