title: Simultaneous determination of pesticide residues and antioxidants in blended oil using a liquid-liquid extraction combined with dispersive solid phase extraction method.
abstract: This article developed a method to detect two antioxidants (butylated hydroxyl anisole (BHA), butylated hydroxyl toluene (BHT)) and twelve pesticides (dichlorvos, pirimicarb, prothiofos, fenitrothion, ethoprophos, malathion, beta-Cypermethrin, profenofos, diazinon, propoxur, procymidon, captan) in blended oil samples after their extraction simultaneously. The establishment of the method was based on two-step process of screening and optimization experiment design. With a Plackett-Burman (PB) design, significant parameters were found by screening experiment and single factor experiment accompanied by a central composite design (CCD) experiment were used to make important parameters optimal. The coefficients of determination (r2) was between 0.9931 and 0.9996 while the limits of quantification (LOQs) and limits of detection (LODs) were found in scope of 0.002-0.04mg·kg-1and 0.0006-0.0012mg·kg-1. Recovery values of analytes were above 74%, at the same time the relative standard deviations (RSDs) under 10% at the concentrations ranging from 0.05mg·kg-1to 0.20mg·kg-1. To sum up, this method with shorter time and fewer consumption of reagents could be employed in various occasions to detect antioxidants and pesticides.
authors.affiliation: College of Food Science and Engineering/Collaborative Innovation Center for Modern Grain Circulation and Safety/Key Laboratory of Grains and Oils Quality Control and Processing, Nanjing University of Finance and Economics, Nanjing 210023, China.
authors.forename: Yong
authors.initials: Y
authors.lastname: Fang
authors.affiliation: College of Food Science and Engineering/Collaborative Innovation Center for Modern Grain Circulation and Safety/Key Laboratory of Grains and Oils Quality Control and Processing, Nanjing University of Finance and Economics, Nanjing 210023, China.
authors.forename: Wen
authors.initials: W
authors.lastname: Tian
authors.affiliation: College of Food Science and Engineering/Collaborative Innovation Center for Modern Grain Circulation and Safety/Key Laboratory of Grains and Oils Quality Control and Processing, Nanjing University of Finance and Economics, Nanjing 210023, China.
authors.forename: Fei
authors.initials: F
authors.lastname: Pei
authors.affiliation: College of Food Science and Engineering/Collaborative Innovation Center for Modern Grain Circulation and Safety/Key Laboratory of Grains and Oils Quality Control and Processing, Nanjing University of Finance and Economics, Nanjing 210023, China.
authors.forename: Peng
authors.initials: P
authors.lastname: Li
authors.affiliation: College of Food Science and Engineering/Collaborative Innovation Center for Modern Grain Circulation and Safety/Key Laboratory of Grains and Oils Quality Control and Processing, Nanjing University of Finance and Economics, Nanjing 210023, China.
authors.forename: XiaoLong
authors.initials: X
authors.lastname: Shao
authors.affiliation: College of Food Science and Engineering/Collaborative Innovation Center for Modern Grain Circulation and Safety/Key Laboratory of Grains and Oils Quality Control and Processing, Nanjing University of Finance and Economics, Nanjing 210023, China.
authors.forename: Yan
authors.initials: Y
authors.lastname: Fan
authors.affiliation: College of Food Science and Engineering/Collaborative Innovation Center for Modern Grain Circulation and Safety/Key Laboratory of Grains and Oils Quality Control and Processing, Nanjing University of Finance and Economics, Nanjing 210023, China. Electronic address: qiuhuihu@njue.edu.cn.
authors.forename: Qiuhui
authors.initials: Q
authors.lastname: Hu
mesh_terms: D000975:Antioxidants / Q000032:analysis*; D059625:Liquid-Liquid Extraction / Q000379:methods*; D010573:Pesticide Residues / Q000032:analysis*; D052616:Solid Phase Extraction / Q000379:methods*
chemical_list: D000975:Antioxidants; D010573:Pesticide Residues
keywords: Antioxidants; Central composite design; Dispersive solid phase extraction; Pesticides; Plackett-Burman experiment