title: Successful Treatment of PD Peritonitis Due toMorganella morganiiResistant to Third-Generation Cephalosporins - A Case Report.
abstract: Morganella morganiiis a rare cause of peritonitis in patients on peritoneal dialysis (PD). Most of the reported cases have resorted to a switch to hemodialysis. We herein report a case of peritonitis due toM. morganiiresistant to third-generation cephalosporins, which was treated successfully with intraperitoneal (IP) tobramycin followed by oral ciprofloxacin. Early microbiologic diagnosis is essential in the treatment of peritonitis from rare microorganisms such asMorganella morganii, and appropriate antibiotic therapy is the key to avoiding catheter loss and subsequent switch to hemodialysis.
authors.affiliation: Division of Nephrology, The Ottawa Hospital and University of Ottawa, Ottawa, ON, Canada vkesk100@uottawa.ca.
authors.forename: Vaibhav
authors.initials: V
authors.lastname: Keskar
authors.affiliation: Division of Nephrology, The Ottawa Hospital and University of Ottawa, Ottawa, ON, Canada.
authors.forename: Mohan
authors.initials: M
authors.lastname: Biyani
authors.affiliation: Division of Nephrology, The Ottawa Hospital and University of Ottawa, Ottawa, ON, Canada.
authors.forename: Syed Obaid
authors.initials: SO
authors.lastname: Amin
authors.affiliation: Division of Nephrology, The Ottawa Hospital and University of Ottawa, Ottawa, ON, Canada.
authors.forename: Greg
authors.initials: G
authors.lastname: Knoll
mesh_terms: D000046:Academic Medical Centers; D000284:Administration, Oral; D002511:Cephalosporins / Q000008:administration & dosage; D002939:Ciprofloxacin / Q000008:administration & dosage*; D004352:Drug Resistance, Microbial; D004359:Drug Therapy, Combination; D004756:Enterobacteriaceae Infections / Q000175:diagnosis / Q000188:drug therapy*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007263:Infusions, Parenteral; D007676:Kidney Failure, Chronic / Q000175:diagnosis / Q000628:therapy; D008875:Middle Aged; D020613:Morganella morganii / Q000187:drug effects / Q000302:isolation & purification; D010530:Peritoneal Dialysis / Q000009:adverse effects* / Q000379:methods; D010538:Peritonitis / Q000188:drug therapy* / Q000209:etiology / Q000382:microbiology*; D014031:Tobramycin / Q000008:administration & dosage*; D016896:Treatment Outcome
chemical_list: D002511:Cephalosporins; D002939:Ciprofloxacin; D014031:Tobramycin
keywords: Morganella morganii; peritoneal dialysis; peritonitis