title: Platelet Rich Plasma: a short overview of certain bioactive components.
abstract: Platelet rich plasma (PRP) represents a relatively new approach in regenerative medicine. It is obtained from patient's own blood and contains different growth factors and other biomolecules necessary for wound healing. Since there are various protocols for PRP preparing, it usually results with PRP generation with different amounts of bioactive substances, which finally may modulate the intensity of wound healing. The reference data about potential effect of some PRP compounds on wound healing, in different tissues, are still controversial. This review summarizes recently known facts about physiological role of certain PRP components and guidance for further research. Also, this review discusses different procedure for PRP generation and potential effect of leukocytes on wound healing.
authors.affiliation: Institute of Physiology, Medical Faculty University of Nis, Bulevar Dr. Zorana Djindjica 81, Nis, Serbia.
authors.forename: Voja
authors.initials: V
authors.lastname: Pavlovic
authors.affiliation: Institute of Physiology, Medical Faculty University of Nis, Nis, Serbia.
authors.forename: Milan
authors.initials: M
authors.lastname: Ciric
authors.affiliation: Orthopedic Clinic, Clinical Centre, Nis, Serbia.
authors.forename: Vladimir
authors.initials: V
authors.lastname: Jovanovic
authors.affiliation: Predrag Stojanovic, Department of Microbiology and Immunology, Nis, Serbia.
authors.forename: Predrag
authors.initials: P
authors.lastname: Stojanovic
keywords: Growth factors; Leukocytes; Platelet rich plasma; Platelets; Wound healing