title: Role of Chirality in Drugs: An Overview.
abstract: Stereochemistry has occupied a great role in the manufacture and development of pharmaceuticals. Chiral properties play an important role in the determination of pharmacological actions of the drug. In recent years, there is a considerable interest in chiral separation to isolate and examine both enantiomers. This article provides an overview about the stereochemistry and its role in drugs, and also, offers approved isolation methods for enantiomeric pairs.
authors.affiliation: Department of Pharmaceutical Chemistry & Drug Control, Faculty of Pharmacy, Arab International University, Syrian Arab Republic.|Department of Chemistry, Faculty of Science, Damascus University, Syrian Arab Republic.
authors.forename: Hourieh
authors.initials: H
authors.lastname: Alkadi
authors.affiliation: Department of Pharmaceutical Chemistry & Drug Control, Faculty of Pharmacy, Arab International University, Syrian Arab Republic.
authors.forename: Rajwa
authors.initials: R
authors.lastname: Jbeily
mesh_terms: D002845:Chromatography; D003460:Crystallization; D015195:Drug Design; D019075:Electrophoresis, Capillary; D006801:Humans; D004364:Pharmaceutical Preparations / Q000032:analysis / Q000737:chemistry / Q000302:isolation & purification; D010599:Pharmacokinetics; D013237:Stereoisomerism
chemical_list: D004364:Pharmaceutical Preparations
keywords: Chirality; chiral drug; chiral separation; enantiomer; pharmacology; stereoisomer.