title: Micronutrients and Their Role in Oral Cancer: A Review.
abstract: Cancer is one of the leading causes of death across the world. Oral cancer is the sixth most common type of cancer in the world. The incidence of oral cancer increases with the increase in the consumption of carcinogens such as tobacco and alcohol as seen in south and southeast Asia. Oral cancer is seen to arise from pre-existing leukoplakia and oral submucous fibrosis. Antioxidants have been hypothesized to be chemopreventive agents for several cancers. Micronutrients such as zinc, copper and selenium, along with antioxidants are required for the production of various enzymes that help prevent DNA damage caused by free radicals.
authors.affiliation: Department of Oral Medicine and Radiology, AB Shetty Memorial Institute of Dental Sciences, Nitte University, Mangalore, India, e-mail: ananyamadiyal@gmail.com.
authors.forename: A
authors.initials: A
authors.lastname: Madiyal
authors.affiliation: Department of Oral Medicine and Radiology, Gulf Medical University, Ajman, United Arab Emirates.
authors.forename: S R
authors.initials: SR
authors.lastname: Shetty
authors.affiliation: Department of Oral Medicine and Radiology, AB Shetty Memorial Institute of Dental Sciences, Nitte University, Mangalore, India.
authors.forename: G S
authors.initials: GS
authors.lastname: Babu
keywords: Antioxidants; micronutrients; oral cancer; trace elements