title: Physical Activity Self-Management and Coaching Compared to Social Interaction in Huntington Disease: Results From the ENGAGE-HD Randomized, Controlled Pilot Feasibility Trial.
abstract: BACKGROUND
  Self-management and self-efficacy for physical activity is not routinely considered in neurologic rehabilitation.
  
  
  OBJECTIVE
  This study assessed feasibility and outcomes of a 14-week physical activity self-management and coaching intervention compared with social contact in Huntington disease (HD) to inform the design of a future full-scale trial.
  
  
  METHODS
  Assessor blind, multisite, randomized pilot feasibility trial.
  
  
  METHODS
  Participants were recruited and assessed at baseline, 16 weeks following randomization, and then again at 26 weeks in HD specialist clinics with intervention delivery by trained coaches in the participants' homes.
  
  
  METHODS
  People with HD were allocated to the ENGAGE-HD physical activity coaching intervention or a social interaction intervention.
  
  
  METHODS
  Eligibility, recruitment, retention, and intervention participation were determined at 16 weeks. Other outcomes of interest included measures of mobility, self-efficacy, physical activity, and disease-specific measures of motor and cognition. Fidelity and costs for both the physical activity and social comparator interventions were established.
  
  
  RESULTS
  Forty percent ( n = 46) of eligible patients were enrolled; 22 were randomized to the physical intervention and 24 to social intervention. Retention rates in the physical intervention and social intervention were 77% and 92%, respectively. Minimum participation criteria were achieved by 82% of participants in the physical intervention and 100% in the social intervention. There was no indication of between-group treatment effects on function; however, increases in self-efficacy for exercise and self-reported levels of physical activity in the physical intervention lend support to our predefined intervention logic model.
  
  
  CONCLUSIONS
  The use of self-report measures may have introduced bias.
  
  
  CONCLUSIONS
  An HD physical activity self-management and coaching intervention is feasible and worthy of further investigation.
authors.affiliation: South East Wales Trials Unit, Centre for Trials Research, Cardiff University, Heath Park, Cardiff, CF14 4YS, United Kingdom.
authors.forename: Monica
authors.initials: M
authors.lastname: Busse
authors.affiliation: Department of Biobehavioral Sciences, Teachers College, Columbia University, New York, New York, and Centre for Trials Research, Cardiff University.
authors.forename: Lori
authors.initials: L
authors.lastname: Quinn
authors.affiliation: South East Wales Trials Unit, Centre for Trials Research, Cardiff University.
authors.forename: Cheney
authors.initials: C
authors.lastname: Drew
authors.affiliation: South East Wales Trials Unit, Centre for Trials Research, Cardiff University.
authors.forename: Mark
authors.initials: M
authors.lastname: Kelson
authors.affiliation: South East Wales Trials Unit, Centre for Trials Research, Cardiff University.
authors.forename: Rob
authors.initials: R
authors.lastname: Trubey
authors.affiliation: South East Wales Trials Unit, Centre for Trials Research, Cardiff University.
authors.forename: Kirsten
authors.initials: K
authors.lastname: McEwan
authors.affiliation: Centre for Health Economics and Medicines Evaluation, Bangor University.
authors.forename: Carys
authors.initials: C
authors.lastname: Jones
authors.affiliation: South East Wales Trials Unit, Centre for Trials Research, Cardiff University.
authors.forename: Julia
authors.initials: J
authors.lastname: Townson
authors.affiliation: Oxford Institute of Nursing and Allied Health Research, Oxford Brookes University.
authors.forename: Helen
authors.initials: H
authors.lastname: Dawes
authors.affiliation: Centre for Health Economics and Medicines Evaluation, Bangor University.
authors.forename: Rhiannon
authors.initials: R
authors.lastname: Tudor-Edwards
authors.affiliation: Cardiff Brain Repair Group, Neuroscience and Mental Health Institute, MRC Centre for Neuropsychiatric Genetics and Genomics, Schools of Medicine and Biosciences, Cardiff University.
authors.forename: Anne
authors.initials: A
authors.lastname: Rosser
authors.affiliation: South East Wales Trials Unit, Centre for Trials Research, Cardiff University.
authors.forename: Kerenza
authors.initials: K
authors.lastname: Hood
mesh_terms: D002985:Clinical Protocols; D005081:Exercise Therapy / Q000379:methods*; D005240:Feasibility Studies; D005260:Female; D015438:Health Behavior; D006801:Humans; D006816:Huntington Disease / Q000503:physiopathology / Q000628:therapy*; D007398:Interpersonal Relations; D008297:Male; D008875:Middle Aged; D009042:Motivation; D010865:Pilot Projects; D012648:Self Care; D016037:Single-Blind Method; D012944:Social Support; D016896:Treatment Outcome; D006113:United Kingdom