title: Patterns of Early-Life Social and Environmental Exposures and Child Cognitive Development, Rhea Birth Cohort, Crete, Greece.
abstract: Early-life exposures are critical for later child cognitive development. McCarthy Scales of Children's Abilities (MSCA) were used to assess cognitive development of 700 preschoolers (Mage= 4.2 years), derived from the "Rhea" birth cohort, in Greece. Principal component analysis (PCA) was applied on prospectively collected exposure data. Six components were extracted; five of them were associated with child cognition. Higher parental social status, preschool attendance and less TV watching, nonsmoking during pregnancy and breastfeeding, and parental involvement in child life were protective factors of child cognition at 4 years. Increased child birth order was negatively associated with child cognition. Offspring's size at birth was not associated with any cognitive outcome. These findings reveal the importance of early-life exposures to child cognitive development.
authors.affiliation: University of Crete.
authors.forename: Mariza
authors.initials: M
authors.lastname: Kampouri
authors.affiliation: University of Crete.
authors.forename: Andriani
authors.initials: A
authors.lastname: Kyriklaki
authors.affiliation: University of Crete.
authors.forename: Theano
authors.initials: T
authors.lastname: Roumeliotaki
authors.affiliation: University of Crete.
authors.forename: Katerina
authors.initials: K
authors.lastname: Koutra
authors.affiliation: University of Crete.
authors.forename: Despoina
authors.initials: D
authors.lastname: Anousaki
authors.affiliation: University of Crete.
authors.forename: Katerina
authors.initials: K
authors.lastname: Sarri
authors.affiliation: University of Crete.
authors.forename: Maria
authors.initials: M
authors.lastname: Vassilaki
authors.affiliation: Centre for Research in Environmental Epidemiology (CREAL).
authors.forename: Manolis
authors.initials: M
authors.lastname: Kogevinas
authors.affiliation: University of Crete.
authors.forename: Leda
authors.initials: L
authors.lastname: Chatzi
mesh_terms: D001942:Breast Feeding / Q000523:psychology; D002657:Child Development / Q000502:physiology*; D002675:Child, Preschool; D003071:Cognition / Q000502:physiology*; D015331:Cohort Studies; D004781:Environmental Exposure; D005260:Female; D006115:Greece; D006801:Humans; D008016:Life Change Events; D008297:Male; D011247:Pregnancy; D011446:Prospective Studies; D012923:Social Class; D013690:Television / Q000706:statistics & numerical data