title: Cytokinin Transporters: GO and STOP in Signaling.
abstract: Cytokinins are phytohormones essential for cytokinesis and many other physiological and developmental processes in planta. Long-distance transport and intercellular transport have been postulated. For these processes, the existence of cytokinin transporters has been suggested. Recently, a transporter loading the xylem (AtABCG14) and another for cellular import (AtPUP14) have been discovered. AtABCG14 participates in the xylem loading process of cytokinins and contributes to the positive regulation of shoot growth. The cellular importer AtPUP14 is required to suppress cytokinin signaling. A role of a transporter as stop signal is a new paradigm for a hormone transporter.
authors.affiliation: Institute of Plant and Microbial Biology, University Zurich, Zollikerstrasse 107, 8008 Zürich, Switzerland. Electronic address: joohyun.kang@botinst.uzh.ch.
authors.forename: Joohyun
authors.initials: J
authors.lastname: Kang
authors.affiliation: Department of Life Sciences, Pohang University of Science and Technology (POSTECH), Pohang 37673, Korea.
authors.forename: Youngsook
authors.initials: Y
authors.lastname: Lee
authors.affiliation: Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya 464-8601, Japan; RIKEN Center for Sustainable Resource Science, 1-7-22 Suehiro, Tsurumi, Yokohama 230-0045, Japan.
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Sakakibara
authors.affiliation: Institute of Plant and Microbial Biology, University Zurich, Zollikerstrasse 107, 8008 Zürich, Switzerland.
authors.forename: Enrico
authors.initials: E
authors.lastname: Martinoia
mesh_terms: D017360:Arabidopsis / Q000235:genetics / Q000378:metabolism*; D029681:Arabidopsis Proteins / Q000235:genetics / Q000378:metabolism*; D001692:Biological Transport / Q000235:genetics / Q000502:physiology; D003583:Cytokinins / Q000378:metabolism; D026901:Membrane Transport Proteins / Q000235:genetics / Q000378:metabolism*; D015398:Signal Transduction / Q000235:genetics / Q000502:physiology
chemical_list: D029681:Arabidopsis Proteins; D003583:Cytokinins; D026901:Membrane Transport Proteins
keywords: ATP-binding cassette transporter; cytokinin signaling; cytokinins; cytokinins transportation; equilibrative nucleoside transporter; purine permease