title: Perinatal and Neonatal Outcomes of Triplet Gestations Based on Chorionicity.
abstract: ObjectiveTo compare perinatal and neonatal outcomes of dichorionic (DC) and monochorionic (MC) with trichorionic (TC) triplet gestations.MethodsA retrospective cohort study of DC + MC versus TC triplet gestations delivered at a tertiary care hospital from 2009 to 2015. The results include 42 sets of triplets (TC,n= 26; DC + MC,n= 16). Maternal demographics and pregnancy data were compared. Neonatal outcomes were assessed using composite morbidity and mortality.ResultsMaternal baseline characteristics including age, mode of conception, race, parity, body mass index, and previous preterm delivery were statistically comparable. Comparison of prenatal management and complications yielded no significant differences in terms of presence of shortened cervix, cerclage placement, use of tocolytics, intrauterine growth restriction, premature rupture of membranes, pregnancy-induced hypertension, or gestational diabetes. However, evaluation of composite morbidity and mortality (RDS, IVH, NEC, IUGR, and death) illustrated that all infants born from DC + MC triplet gestations suffered some morbidity or mortality compared with TC pregnancies (p< 0.01).ConclusionDC + MC triplet gestations are at an increased risk of neonatal morbidity and mortality compared with TC triplet gestations.
authors.affiliation: Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Advocate Lutheran General Hospital, Park Ridge, Illinois.
authors.forename: Maureen
authors.initials: M
authors.lastname: Downing
authors.affiliation: The James R. and Helen D. Russell Institute for Research & Innovation, Advocate Lutheran General Hospital, Park Ridge, Illinois.
authors.forename: Suela
authors.initials: S
authors.lastname: Sulo
authors.affiliation: Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Advocate Lutheran General Hospital, Park Ridge, Illinois.
authors.forename: Barbara V
authors.initials: BV
authors.lastname: Parilla
keywords: diamniotic; dichorionic triplets; monochorionic triplets; monochorionic twin pair in triplet gestation; triplet gestation outcomes; triplet outcomes based on chorionicity