title: Controlled clinical trial addressing teeth whitening with hydrogen peroxide in adolescents: a 12-month follow-up.
abstract: To evaluate the colorimetric change in incisors and canines of adolescents aged 12 to 20 years submitted to at-home whitening and to evaluate satisfaction, sensitivity and discomfort during the procedures through a questionnaire.
  Thirty adolescents were randomly assigned to the following groups: 1) 6.0% hydrogen peroxide (White Class with calcium - FGM); 2) 7.5% hydrogen peroxide (White Class with calcium - FGM); 3) 10% hydrogen peroxide (Oral B 3D White - Oral-B); 4) Control group - placebo. Assessments were performed prior to treatment as well as at 7, 30, 180 and 360 days after treatment. Friedman's ANOVA was used to analyze color. The Kruskal-Wallis test followed by Dunn's post hoc test was used to compare the groups at the different evaluation times. Answers on the questionnaires were ranked, and non-parametrical tests were employed. The groups were compared in each period using the Kruskal-Wallis test followed by the Student-Newman-Keuls test. Categorical data were analyzed using Fisher's exact test, and the Wilcoxon test was used for the analysis of different periods. P-values were corrected using the Hyan-Holm step-down Bonferroni procedure. Clinicaltrials.gov: NCT01998386.
  Similar results were obtained one month after treatment with both tooth whitening gels and whitening strips. Patients were partially satisfied with the treatment after the first and second weeks and would recommend it. All products demonstrated color stability after 12 months of follow-up.
  The bleaching procedure was efficient, and the patients could perceive its result. Further investigations are needed to determine the effects of bleaching on young teeth.
authors.forename: Marcelo Mendes
authors.initials: MM
authors.lastname: Pinto
authors.affiliation: Universidade Nove de Julho, Programa de Pós-Graduação, Departamento de Biofotônica Aplicada ès Ciências da Saúde, São Paulo/, SP, Brazil.
authors.forename: Marcela Leticia Leal
authors.initials: ML
authors.lastname: Gonçalves
authors.affiliation: Universidade Nove de Julho, Programa de Pós-Graduação, Departamento de Biofotônica Aplicada ès Ciências da Saúde, São Paulo/, SP, Brazil.
authors.forename: Ana Carolina Costa da
authors.initials: AC
authors.lastname: Mota
authors.affiliation: Universidade Nove de Julho, Programa de Pós-Graduação, Departamento de Biofotônica Aplicada ès Ciências da Saúde, São Paulo/, SP, Brazil.
authors.forename: Alessandro Melo
authors.initials: AM
authors.lastname: Deana
authors.affiliation: Universidade Nove de Julho, Programa de Pós-Graduação, Departamento de Biofotônica Aplicada ès Ciências da Saúde, São Paulo/, SP, Brazil.
authors.forename: Silvia Regina
authors.initials: SR
authors.lastname: Olivan
authors.affiliation: Universidade Nove de Julho, Programa de Pós-Graduação, Departamento de Biofotônica Aplicada ès Ciências da Saúde, São Paulo/, SP, Brazil.
authors.forename: Carolina
authors.initials: C
authors.lastname: Bortoletto
authors.affiliation: Universidade Nove de Julho, Programa de Pós-Graduação, Departamento de Biofotônica Aplicada ès Ciências da Saúde, São Paulo/, SP, Brazil.
authors.forename: Camila Haddad Leal de
authors.initials: CH
authors.lastname: Godoy
authors.affiliation: Universidade Nove de Julho, Programa de Pós-Graduação, Departamento de Biofotônica Aplicada ès Ciências da Saúde, São Paulo/, SP, Brazil.
authors.forename: Katia Lumi Tanikawa
authors.initials: KL
authors.lastname: Vergilio
authors.affiliation: Universidade Nove de Julho, Programa de Pós-Graduação, Departamento de Biofotônica Aplicada ès Ciências da Saúde, São Paulo/, SP, Brazil.
authors.forename: Olga Maria
authors.initials: OM
authors.lastname: Altavista
authors.affiliation: Universidade Nove de Julho, Programa de Pós-Graduação, Departamento de Biofotônica Aplicada ès Ciências da Saúde, São Paulo/, SP, Brazil.
authors.forename: Lara J
authors.initials: LJ
authors.lastname: Motta
authors.affiliation: Universidade Nove de Julho, Programa de Pós-Graduação, Departamento de Biofotônica Aplicada ès Ciências da Saúde, São Paulo/, SP, Brazil.
authors.forename: Sandra Kalil
authors.initials: SK
authors.lastname: Bussadori
mesh_terms: D000293:Adolescent; D000704:Analysis of Variance; D002118:Calcium; D002648:Child; D003116:Color; D003124:Colorimetry; D003807:Dentin Sensitivity / Q000139:chemically induced; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006861:Hydrogen Peroxide; D008297:Male; D017060:Patient Satisfaction; D015203:Reproducibility of Results; D012646:Self Administration; D018709:Statistics, Nonparametric; D011795:Surveys and Questionnaires; D013997:Time Factors; D014073:Tooth Bleaching / Q000379:methods*; D058205:Tooth Bleaching Agents; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D058205:Tooth Bleaching Agents; D006861:Hydrogen Peroxide; D002118:Calcium