title: Validation of the Mini-OAKHQOL for use in patients with osteoarthritis in Spain.
abstract: The Mini-Osteoarthritis Knee and Hip Quality of Life (Mini-OAKHQOL) questionnaire osteoarthritis is specific to individuals with knee or hip osteoarthritis. The objective of this study was to perform a validation of the Mini-OAKHQOL for use in Spain in terms of its psychometric properties of reliability, validity and responsiveness. Patients with osteoarthritis from the waiting list for a joint replacement completed the OAKHQOL, Short Form 36 Health Survey and Western Ontario and McMaster Universities Osteoarthritis Index. Reliability was assessed in terms of internal consistency and test-retest data, and convergent validity using Spearman's correlation coefficient. Structural validity was investigated by confirmatory factor analysis, and Rasch analysis was used to examine the unidimensionality of the scales. Responsiveness was assessed by calculating effect sizes. Confirmatory factor analysis confirmed the five-factor model, and the results of the Rasch analyses supported the unidimensionality assumption, with infit and outfit statistics. Cronbach's alpha ranged from 0.76 to 0.89 for all except the social dimensions. Statistically significant differences were observed between patients with different degrees of disease severity on all dimensions. There was convergent validity among dimensions expected to be correlated. The OAKHQOL questionnaire showed good responsiveness, with large changes for all dimensions apart from the two social dimensions, which had small effect sizes. Results of the study support the view that the Spanish version of the Mini-OAKHQOL questionnaire is a valid instrument to measure health-related quality of life in patients with osteoarthritis of the lower limb.
authors.affiliation: Basurto University Hospital, Jado, 4th Floor, Avda. Montevideo 18, 48013, Bilbao, Spain. marta.gonzalezsaenzdetejada@osakidetza.eus.|Health Services Research on Chronic Patients Network (REDISSEC), Galdakao, Spain. marta.gonzalezsaenzdetejada@osakidetza.eus.
authors.forename: Marta
authors.initials: M
authors.lastname: Gonzalez Sáenz de Tejada
authors.affiliation: Basurto University Hospital, Jado, 4th Floor, Avda. Montevideo 18, 48013, Bilbao, Spain.|Health Services Research on Chronic Patients Network (REDISSEC), Galdakao, Spain.
authors.forename: Amaia
authors.initials: A
authors.lastname: Bilbao
authors.affiliation: Health Services Research on Chronic Patients Network (REDISSEC), Galdakao, Spain.|Hospital Virgen de las Nieves, Avda. de las Fuerzas Armadas 2, Granada, Spain.
authors.forename: Carmen
authors.initials: C
authors.lastname: Herrera
authors.affiliation: Health Services Research on Chronic Patients Network (REDISSEC), Galdakao, Spain.|Planning and Evaluation Service, Canary Islands Health Service, C/ Pérez de Rozas, n°5, 4th Floor, 38004, Santa Cruz de Tenerife, Spain.
authors.forename: Lidia
authors.initials: L
authors.lastname: García
authors.affiliation: Health Services Research on Chronic Patients Network (REDISSEC), Galdakao, Spain.|Hospital of Donostia, Paseo Dr. Beguiristain s/n, 20014, Donostia-San Sebastian, Spain.
authors.forename: Cristina
authors.initials: C
authors.lastname: Sarasqueta
authors.affiliation: Basurto University Hospital, Jado, 4th Floor, Avda. Montevideo 18, 48013, Bilbao, Spain.|Health Services Research on Chronic Patients Network (REDISSEC), Galdakao, Spain.
authors.forename: Antonio
authors.initials: A
authors.lastname: Escobar
mesh_terms: D000368:Aged; D005163:Factor Analysis, Statistical; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015207:Osteoarthritis, Hip / Q000523:psychology*; D020370:Osteoarthritis, Knee / Q000523:psychology*; D010147:Pain Measurement; D011446:Prospective Studies; D011594:Psychometrics; D011788:Quality of Life / Q000523:psychology*; D015203:Reproducibility of Results; D013030:Spain; D011795:Surveys and Questionnaires
keywords: Health-related quality of life; Mini-OAKHQOL; Osteoarthritis; Validation