title: Candida Blood Stream Infection in Neonates: Experience from A Tertiary Care Teaching Hospital of Central India.
abstract: OBJECTIVE
  To assess the epidemiology of neonatal Candida blood stream infection.
  
  
  METHODS
  Medical records of neonates with Candida blood stream infection over 5 years (September 2010 to August 2015) were reviewed. Clinical details, species distribution and antifungal susceptibility were noted.
  
  
  RESULTS
  114 neonates developed Candida blood stream infection. Commonly isolated Candida species were C. tropicalis, C. albicans and C. parapsilosis. Susceptibility for fluconazole and amphotericin B was 86.6% and 68.3%, respectively. Central line >7 days and hospital stay >28 days were independent risk factors associated with non-albicans Candida infection.
  
  
  CONCLUSIONS
  Early removal of central line, timely fungal culture and antifungal susceptibility are necessary for early and appropriate treatment and better outcome.
authors.affiliation: Departments of Pediatrics and *Microbiology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India. Correspondence to: Dr. Sriparna Basu, Professor, Neonatal Unit, Department of Pediatrics, Institute of Medical Sciences, Banaras Hindu University, Varanasi 221 005, India. drsriparnabasu@rediffmail.com.
authors.forename: Sriparna
authors.initials: S
authors.lastname: Basu
authors.forename: Rajesh
authors.initials: R
authors.lastname: Kumar
authors.forename: Ragini
authors.initials: R
authors.lastname: Tilak
authors.forename: Ashok
authors.initials: A
authors.lastname: Kumar
mesh_terms: D000935:Antifungal Agents / Q000627:therapeutic use; D058387:Candidemia / Q000188:drug therapy / Q000453:epidemiology*; D005260:Female; D006784:Hospitals, Teaching; D006801:Humans; D007194:India; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000188:drug therapy / Q000453:epidemiology*; D008297:Male; D012189:Retrospective Studies; D012307:Risk Factors; D063128:Tertiary Health Care; D016896:Treatment Outcome
chemical_list: D000935:Antifungal Agents