title: Periosteal mesenchymal chondrosarcoma of the tibia with multifocal bone metastases: a case report.
abstract: Mesenchymal chondrosarcoma of bone is a rare high-grade variant of chondrosarcoma, which typically has central intramedullary location. The tumor is characterized by admixture of highly anaplastic small round malignant cells and islands of mineralized low-grade hyaline cartilage. It is most unusual for this tumor to arise on the surface of a long bone. We describe a patient with periosteal mesenchymal chondrosarcoma that arose at the surface of the right tibia with multifocal bone metastases. Radiographic, CT, MRI, and PET-CT features of this unusual tumor are presented.
authors.affiliation: Department of Diagnostic Imaging, The University of Texas M.D. Anderson Cancer Center, Unit 1475, 1515 Holcombe Blvd, Unit 1475, Houston, Texas, 77030, USA. rajkumar@mdanderson.org.
authors.forename: Rajendra
authors.initials: R
authors.lastname: Kumar
authors.affiliation: Department of Diagnostic Imaging, The University of Texas M.D. Anderson Cancer Center, Unit 1475, 1515 Holcombe Blvd, Unit 1475, Houston, Texas, 77030, USA.
authors.forename: Cihan
authors.initials: C
authors.lastname: Duran
authors.affiliation: Department of Diagnostic Imaging, The University of Texas M.D. Anderson Cancer Center, Unit 1475, 1515 Holcombe Blvd, Unit 1475, Houston, Texas, 77030, USA.
authors.forename: Behrang
authors.initials: B
authors.lastname: Amini
authors.affiliation: Department of Medical Oncology, The University of Texas M.D. Anderson Cancer Center, Unit 1475, 1515 Holcombe Blvd, Unit 1475, Houston, Texas, 77030, USA.
authors.forename: Dejka M
authors.initials: DM
authors.lastname: Araujo
authors.affiliation: Department of Pathology, The University of Texas M.D. Anderson Cancer Center, Unit 1475, 1515 Holcombe Blvd, Unit 1475, Houston, Texas, 77030, USA.
authors.forename: Wei-Lien
authors.initials: WL
authors.lastname: Wang
mesh_terms: D000328:Adult; D001859:Bone Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology*; D018211:Chondrosarcoma, Mesenchymal / Q000000981:diagnostic imaging* / Q000473:pathology*; D003287:Contrast Media; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D013125:Spinal Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary; D013977:Tibia
chemical_list: D003287:Contrast Media
keywords: Periosteal chondroid bone tumor; Periosteal mesenchymal chondrosarcoma; Surface bone chondrosarcoma; Surface chondroid bone tumor