title: Non-traumatic keratitis due toColletotrichum truncatum.
abstract: BACKGROUND
  The fungal genusColletotrichumis an uncommon cause of human infections. It has been implicated in cutaneous phaeohyphomycosis, artritis and keratitis secondary to traumatic implantation.
  
  
  METHODS
  We report two cases of keratitis dueColletotrichum truncatumin middle-aged, immunocompetent persons without history of trauma. The aetiological agents were identified based on DNA sequencing. Azoles and echinocandins showed high minimal inhibitory concentrations while amphotericin B was ≤ 0.25  mg l-1. Both patients failed topical antifungal treatment and needed penetrating keratoplasty with a favourable outcome.
  
  
  CONCLUSIONS
  C. truncatumcaused keratomycosis which did not respond to topical antifungal agents. To the best of our knowledge these are the first reported cases of keratitis due to this fungus in Cuba and Latin-America and highlights the expanding spectrum of fungal agents causing eye infections.
authors.affiliation: Department of Microbiology, Ophthalmological Institute "Ramón Pando Ferrer", Havana, Cuba.
authors.forename: Reina
authors.initials: R
authors.lastname: Llamos
authors.affiliation: Fungal Biodiversity Centre (CBS-KNAW) , Utrecht , the Netherlands.
authors.forename: Abdullah M S
authors.initials: AM
authors.lastname: Al-Hatmi
authors.affiliation: Department of Bacteriology and Mycology, Tropical Medicine Institute "Pedro Kouri" , Havana , Cuba.
authors.forename: Gerardo
authors.initials: G
authors.lastname: Martínez
authors.affiliation: Department of Medical Microbiology and Infectious Diseases, Canisius-Wilhelmina Hospital , Nijmegen , the Netherlands.
authors.forename: Ferry
authors.initials: F
authors.lastname: Hagen
authors.affiliation: Department of Bacteriology and Mycology, Tropical Medicine Institute "Pedro Kouri" , Havana , Cuba.
authors.forename: Rosario
authors.initials: R
authors.lastname: Velar
authors.affiliation: Clinical Department, Ophthalmological Hospital "Ramón Pando Ferrer" , Havana , Cuba.
authors.forename: Alexeide
authors.initials: A
authors.lastname: de la Caridad Castillo Pérez
authors.affiliation: Department of Medical Microbiology and Infectious Diseases, Canisius-Wilhelmina Hospital, Nijmegen, the Netherlands; Department of Medical Microbiology, Radboud University Medical Center, Nijmegen, the Netherlands.
authors.forename: Jacques F
authors.initials: JF
authors.lastname: Meis
authors.affiliation: Department of Bacteriology and Mycology, Tropical Medicine Institute "Pedro Kouri" , Havana , Cuba.
authors.forename: María T
authors.initials: MT
authors.lastname: Illnait-Zaragozí
keywords: Colletotrichum; keratomycosis; mycotic keratitis