title: Biomimetic and bioinspired nanoparticles for targeted drug delivery.
abstract: In drug targeting, the urgent need for more effective and less iatrogenic therapies is pushing toward a complete revision of carrier setup. After the era of 'articles used as homing systems', novel prototypes are now emerging. Newly conceived carriers are endowed with better biocompatibility, biodistribution and targeting properties. The biomimetic approach bestows such improved functional properties. Exploiting biological molecules, organisms and cells, or taking inspiration from them, drug vector performances are now rapidly progressing toward the perfect carrier. Following this direction, researchers have refined carrier properties, achieving significant results. The present review summarizes recent advances in biomimetic and bioinspired drug vectors, derived from biologicals or obtained by processing synthetic materials with a biomimetic approach.
authors.affiliation: IMT School for Advanced Studies Lucca, Piazza San Francesco, 19, 55100, Lucca, Italy.
authors.forename: Mariacristina
authors.initials: M
authors.lastname: Gagliardi
mesh_terms: D040761:Biomimetic Materials; D016503:Drug Delivery Systems; D006801:Humans; D053758:Nanoparticles; D014018:Tissue Distribution
keywords: bioinspiration; biomimicry; drug targeting