title: Radiographic changes of cervical destructive spondyloarthropathy in long-term hemodialysis patients: A 9-year longitudinal observational study.
abstract: Analyses of radiographic changes and clinical symptom of destructive spondyloarthropathy (DSA) on consecutive 42 patients managed with long-term hemodialysis were performed to elucidate radiographic changes of DSA and the factors that influence to the destructive changes. Patients underwent plain radiographs of the cervical spine with 9 years interval. Grading of radiological feature from lateral view was classified into grade 0 to grade 3. Clinical symptom was evaluated using modified Japanese Orthopaedic Association scoring system for cervical myelopathy (mJOA score). Destructive changes were observed in 3 patients at the first examination, and those were observed in 15 patients 9 years after the first examination. There is no statistically significant difference between the duration of hemodialysis and the grade. The mean age at the onset of hemodialysis, however, was significantly higher in patients of grade 2 and 3 than those of grade 1. Older patients with long-term hemodialysis had destructive changes. Destructive changes commonly observed in lower cervical spine. The average numbers of the involved disc level were 1.6 in grade 2 and 1.0 in grade 3. Clinical symptoms were varied in each grade and there was no statistically significant difference in total mJOA score among these grades. J. Med. Invest. 64: 68-73, February, 2017.
authors.affiliation: Department of Orthopedic Surgery, Tokushima University.
authors.forename: Akihiro
authors.initials: A
authors.lastname: Nagamachi
authors.forename: Mitsuhiko
authors.initials: M
authors.lastname: Takahashi
authors.forename: Noriaki
authors.initials: N
authors.lastname: Mima
authors.forename: Keisuke
authors.initials: K
authors.lastname: Adachi
authors.forename: Kazumasa
authors.initials: K
authors.lastname: Inoue
authors.forename: Subash C
authors.initials: SC
authors.lastname: Jha
authors.forename: Akihiro
authors.initials: A
authors.lastname: Nitta
authors.forename: Masatoshi
authors.initials: M
authors.lastname: Morimoto
authors.forename: Tomoya
authors.initials: T
authors.lastname: Takasago
authors.forename: Toshiyuki
authors.initials: T
authors.lastname: Iwame
authors.forename: Keizo
authors.initials: K
authors.lastname: Wada
authors.forename: Fumitake
authors.initials: F
authors.lastname: Tezuka
authors.forename: Kazuta
authors.initials: K
authors.lastname: Yamashita
authors.forename: Humio
authors.initials: H
authors.lastname: Hayashi
authors.forename: Ryo
authors.initials: R
authors.lastname: Miyagi
authors.forename: Toshihiko
authors.initials: T
authors.lastname: Nishisyo
authors.forename: Ichiro
authors.initials: I
authors.lastname: Tonogai
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Goto
authors.forename: Yoichiro
authors.initials: Y
authors.lastname: Takata
authors.forename: Toshinori
authors.initials: T
authors.lastname: Sakai
authors.forename: Kosaku
authors.initials: K
authors.lastname: Higashino
authors.forename: Takashi
authors.initials: T
authors.lastname: Chikawa
authors.forename: Koichi
authors.initials: K
authors.lastname: Sairyo
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002574:Cervical Vertebrae / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D011859:Radiography; D006435:Renal Dialysis / Q000009:adverse effects*; D025242:Spondylarthropathies / Q000000981:diagnostic imaging* / Q000209:etiology* / Q000503:physiopathology