title: Diabetes and elevated urea level predict for uretero-ileal stricture after radical cystectomy and ileal conduit formation.
abstract: BACKGROUND
  Benign uretero-ileal anastomotic stricture is a significant complication following radical cystectomy and ileal conduit urinary diversion after radical cystectomy. We examined risk factors for stricture formation to predict those at greatest stricture risk.
  
  
  METHODS
  A retrospective chart review was conducted for patients undergoing radical cystectomy and ileal conduit diversion between 2002 and 2012. Demographic data and patient variables were analyzed to determine risk factors for uretero-ileal stricture using multivariate logistic regression.
  
  
  RESULTS
  Over the study period, 133 patients underwent cystectomy and ileal conduit formation, with 14 (10.5%) developing uretero-ileal anastomotic stricture. Diabetes and elevated serum urea level (defined as >7.1 mmol/L) were associated with increased risk for development of uretero-ileal stricture (odds ratio 4.31 and 4.28, respectively; p<0.05 for each).
  
  
  CONCLUSIONS
  In this patient cohort, diabetes and elevated serum urea level were predictive for the development of uretero-ileal anastomotic stricture. Further prospective study with larger patient samples is required.
authors.affiliation: Department of Urology, Austin Hospital, University of Melbourne, Australia.
authors.forename: Nathan
authors.initials: N
authors.lastname: Hoag
authors.affiliation: Department of Urology, Austin Hospital, University of Melbourne, Australia.
authors.forename: Nathan
authors.initials: N
authors.lastname: Papa
authors.affiliation: Department of Urology, Austin Hospital, University of Melbourne, Australia.
authors.forename: Bhawanie Koonj
authors.initials: BK
authors.lastname: Beharry
authors.affiliation: Department of Urology, Austin Hospital, University of Melbourne, Australia.
authors.forename: Nathan
authors.initials: N
authors.lastname: Lawrentschuk
authors.affiliation: Department of Urology, Austin Hospital, University of Melbourne, Australia.
authors.forename: Danny
authors.initials: D
authors.lastname: Chiu
authors.affiliation: Department of Urology, Austin Hospital, University of Melbourne, Australia.
authors.forename: Shomik
authors.initials: S
authors.lastname: Sengupta
authors.affiliation: Department of Urology, Austin Hospital, University of Melbourne, Australia.
authors.forename: Damien
authors.initials: D
authors.lastname: Bolton