title: Effect of different types of anesthesia on intraoperative blood glucose of diabetic patients: A PRISMA-compliant systematic review and meta-analysis.
abstract: BACKGROUND
  Systematic review which analyzes the impact of different anesthesia on intraoperative blood glucose levels of diabetes patients.
  
  
  METHODS
  We searched Medline (via PubMed), Embase, Cochrane Library, Web of Science, Wangfang, CNKI, and CBM database through June 2016, included in randomized controlled trial (RCT), about different anesthesia on intraoperative blood glucose levels in patients with diabetes. Two researchers in 1 group independently screened literatures with eligibility criteria, extracted information, and used RevMan5.3 software to perform meta-analysis.
  
  
  RESULTS
  We included 11 trials and performed the meta-analysis with 10 trials. The meta-analysis results suggested that compared with general anesthesia, the combined general-epidural anesthesia has a better glycemic control in intraoperative blood glucose levels (WMD -1.26, 95% confidence interval [CI] -1.77 to 0.76), the epidural anesthesia had no significant effects compared with general anesthesia (WMD -0.74, 95% CI 4.41-2.92), and the combined spinal-epidural anesthesia had no significant effects compared with epidural anesthesia (WMD -0.28, 95% CI -1.02 to 0.46). One study suggested that compared with epidural anesthesia, the combined general-epidural anesthesia can lower blood glucose levels CONCLUSION:: Existing evidence showed that compared with general anesthesia, the combined general-epidural anesthesia has a better glycemic control in intraoperative blood glucose levels.
authors.affiliation: Department of Endocrinology, Chinese PLA General Hospital, Beijing Department of Gerontology, First Affiliated Hospital of Kunming Medical University, Kunming Affiliated Hospital of Academy of Military Medical Sciences (PLA 307 Hospital) Department of Endocrinology, Chinese PLA General Hospital, Beijing Evidence-Based Medicine Center, Basic Medical Sciences, Lanzhou University, Lanzhou, China.
authors.forename: Xueqiong
authors.initials: X
authors.lastname: Li
authors.forename: Jinjing
authors.initials: J
authors.lastname: Wang
authors.forename: Kang
authors.initials: K
authors.lastname: Chen
authors.forename: Yijun
authors.initials: Y
authors.lastname: Li
authors.forename: Haibin
authors.initials: H
authors.lastname: Wang
authors.forename: Yiming
authors.initials: Y
authors.lastname: Mu
authors.forename: Yaolong
authors.initials: Y
authors.lastname: Chen
mesh_terms: D000758:Anesthesia / Q000009:adverse effects*; D001786:Blood Glucose / Q000187:drug effects*; D003920:Diabetes Mellitus / Q000097:blood*; D006801:Humans
chemical_list: D001786:Blood Glucose