title: Vaginal delivery after placental abruption with intrauterine fetal death: A 20-year single-center experience.
abstract: OBJECTIVE
  The aim of this study was to elucidate the feasibility and safety of vaginal delivery (VD) when placental abruption causes fetal demise.
  
  
  METHODS
  We conducted a retrospective study of women who were managed for placental abruption with intrauterine fetal death at Kyoto University Hospital during the period from 1995 to 2015.
  
  
  RESULTS
  Sixteen cases were identified during the study period. VD was attempted in 15 cases and was accomplished in 14 (93.3%) cases. The median gestational age was 36 (24-39) weeks, and there were eight primiparas. The median Bishop score on admission was 2.5 (1-9). Eight pregnancies were complicated with pregnancy-induced hypertension. The median duration of labor was 5 h and 18 min (30 min-12 h 43 min), and the median amount of hemorrhage was 2503 (445-6808) mL. Fresh frozen plasma (≥ 20 U) and red cell concentrate (≥ 10 U) were administered in 10 (71%) and 9 (64%) cases, respectively. Two cases required uterine artery embolization for post-partum hemorrhage, while there was no case of maternal death or hysterectomy. Patients with Bishop score > 3 (n = 6) experienced shorter-duration deliveries (P = 0.020) and had significantly larger blood loss volume (P = 0.020) compared to patients with Bishop score ≤ 3. The duration of labor was negatively correlated with the amount of blood loss (R2= -0.56, P = 0.039).
  
  
  CONCLUSIONS
  After placental abruption with intrauterine fetal death, VD is feasible and safe regardless of gestational age, parity, cervical maturity, and duration of labor when intensive medical resources are available.
authors.affiliation: Department of Gynaecology and Obstetrics, Kyoto University, Kyoto, Japan.
authors.forename: Ayami
authors.initials: A
authors.lastname: Inoue
authors.affiliation: Department of Gynaecology and Obstetrics, Kyoto University, Kyoto, Japan.
authors.forename: Eiji
authors.initials: E
authors.lastname: Kondoh
authors.affiliation: Department of Gynaecology and Obstetrics, Kyoto University, Kyoto, Japan.
authors.forename: Koh
authors.initials: K
authors.lastname: Suginami
authors.affiliation: Department of Gynaecology and Obstetrics, Kyoto University, Kyoto, Japan.
authors.forename: Shingo
authors.initials: S
authors.lastname: Io
authors.affiliation: Department of Gynaecology and Obstetrics, Kyoto University, Kyoto, Japan.
authors.forename: Yoshitsugu
authors.initials: Y
authors.lastname: Chigusa
authors.affiliation: Department of Gynaecology and Obstetrics, Kyoto University, Kyoto, Japan.
authors.forename: Ikuo
authors.initials: I
authors.lastname: Konishi
mesh_terms: D000037:Abruptio Placentae / Q000628:therapy*; D000328:Adult; D036861:Delivery, Obstetric / Q000009:adverse effects / Q000379:methods / Q000592:standards; D005260:Female; D005313:Fetal Death; D006801:Humans; D017063:Outcome Assessment, Health Care; D011247:Pregnancy; D055815:Young Adult
keywords: blood loss; duration of labor; intrauterine fetal death; placental abruption; vaginal delivery