title: GenomeScope: fast reference-free genome profiling from short reads.
abstract: CONCLUSIONS
  GenomeScope is an open-source web tool to rapidly estimate the overall characteristics of a genome, including genome size, heterozygosity rate and repeat content from unprocessed short reads. These features are essential for studying genome evolution, and help to choose parameters for downstream analysis. We demonstrate its accuracy on 324 simulated and 16 real datasets with a wide range in genome sizes, heterozygosity levels and error rates.
  
  
  METHODS
  http://genomescope.org , https://github.com/schatzlab/genomescope.git .
  
  
  BACKGROUND
  mschatz@jhu.edu.
  
  
  BACKGROUND
  Supplementary data are available at Bioinformatics online.
authors.affiliation: Simons Center for Quantitative Biology, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.
authors.forename: Gregory W
authors.initials: GW
authors.lastname: Vurture
authors.affiliation: Departments of Computer Science and Biology, Johns Hopkins University, Baltimore, MD, USA.
authors.forename: Fritz J
authors.initials: FJ
authors.lastname: Sedlazeck
authors.affiliation: Simons Center for Quantitative Biology, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.
authors.forename: Maria
authors.initials: M
authors.lastname: Nattestad
authors.affiliation: Simons Center for Quantitative Biology, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.
authors.forename: Charles J
authors.initials: CJ
authors.lastname: Underwood
authors.affiliation: Simons Center for Quantitative Biology, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.|Department of Applied Mathematics and Statistics, Stony Brook University, Stony Brook, NY, USA.
authors.forename: Han
authors.initials: H
authors.lastname: Fang
authors.affiliation: Simons Center for Quantitative Biology, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.
authors.forename: James
authors.initials: J
authors.lastname: Gurtowski
authors.affiliation: Simons Center for Quantitative Biology, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.|Departments of Computer Science and Biology, Johns Hopkins University, Baltimore, MD, USA.
authors.forename: Michael C
authors.initials: MC
authors.lastname: Schatz
mesh_terms: D000818:Animals; D019295:Computational Biology / Q000379:methods*; D019143:Evolution, Molecular; D016678:Genome; D059646:Genome Size; D006579:Heterozygote; D020407:Internet; D017422:Sequence Analysis, DNA / Q000379:methods*; D012984:Software