title: Paliperidone: As a Possible Cause of Pericardial Effusion.
abstract: Paliperidone which is the active metabolite of risperidon is one of the novel antipsychotics. Controlled clinical studies proved its effectiveness on decreasing the positive and negative symptoms of schizophrenia. Some studies and case reports, reported its cardiovascular and cardiometabolic side effects. Cardiac tamponade, that may be mortal, wasn't reported as a side effect with paliperidone usage before. We present a 40 years old female with catatonic schizophrenia for eighteen years, whom was on 6 mg/day paliperidon for 3 years and presented with pericardial tamponade. We suggest that paliperdione may have cardiovascular and cardiometabolic side effects also in therapeutic doses.
authors.affiliation: Department of Psychiatry, Cumhuriyet University Faculty of Medicine Hospital, Sivas, Turkey.
authors.forename: Musa
authors.initials: M
authors.lastname: Şahpolat
authors.affiliation: Department of Cardiology, Cumhuriyet University Faculty of Medicine Hospital, Sivas Sivas, Turkey.
authors.forename: Zekeriya
authors.initials: Z
authors.lastname: Küçükdurmaz
authors.affiliation: Department of Psychiatry, Cumhuriyet University Faculty of Medicine Hospital, Sivas, Turkey.
authors.forename: Önder
authors.initials: Ö
authors.lastname: Kavakçi
authors.affiliation: Department of Cardiology, Cumhuriyet University Faculty of Medicine Hospital, Sivas Sivas, Turkey.
authors.forename: Recep
authors.initials: R
authors.lastname: Kurt
keywords: Paliperidone; cardiotoxic side effects of antipsychoticse; pericardial effüsion