title: Use of near-infrared spectroscopy (NIRS) in cerebral tissue oxygenation monitoring in neonates.
abstract: Near-infrared spectroscopy (NIRS) is a technology capable of non-invasive, continuous measuring of regional tissue oxygen saturation (StO2). StO2represents a state of hemodynamic stability, which is influenced by many factors. Extensive research has been done in the field of measuring StO2of various organs. The current clinical availability of several NIRS-based devices reflects an important development in prevention, detection and correction of discrepancy in oxygen delivery to the brain and vital organs. Managing cerebral ischemia remains a significant issue in the neonatal intensive care units (NICU). Cerebral tissue oxygenation (cStO2) and cerebral fractional tissue extraction (cFTOE) are reported in a large number of clinical studies. This review provides a summary of the concept of function, current variability of NIRS-based devices used in neonatology, clinical applications in continuous cStO2monitoring, limitations, disadvantages, and the potential of current technology.
authors.affiliation: Department of Neonatology, Jessenius Medical Faculty in Martin, Comenius University in Bratislava and University Hospital in Martin, Slovak Republic.
authors.forename: Rene
authors.initials: R
authors.lastname: Gumulak
authors.affiliation: Department of Neonatology, Jessenius Medical Faculty in Martin, Comenius University in Bratislava and University Hospital in Martin, Slovak Republic.
authors.forename: Lucia Casnocha
authors.initials: LC
authors.lastname: Lucanova
authors.affiliation: Department of Neonatology, Jessenius Medical Faculty in Martin, Comenius University in Bratislava and University Hospital in Martin, Slovak Republic.
authors.forename: Mirko
authors.initials: M
authors.lastname: Zibolen
mesh_terms: D002545:Brain Ischemia / Q000175:diagnosis* / Q000628:therapy*; D005260:Female; D006801:Humans; D006931:Hyperbaric Oxygenation / Q000379:methods*; D007231:Infant, Newborn; D007363:Intensive Care Units, Neonatal; D008297:Male; D008991:Monitoring, Physiologic / Q000295:instrumentation / Q000379:methods; D010092:Oximetry / Q000295:instrumentation* / Q000379:methods*; D019265:Spectroscopy, Near-Infrared
keywords: cerebral monitoring; cerebral tissue oxygenation; near-infrared spectroscopy; neonate