title: Palladium-Catalyzed Cleavage of α-Allenylic Aryl Ether toward Pyrazolemethylene-Substituted Phosphinyl Allenes and Their Transformations via Alkenyl C-P(O) Cleavage.
abstract: A palladium-catalyzed two-component coupling of allenylphosphine oxides with conjugated N-tosylhydrazones is revealed. For the first time, the cleavage of α-allenylic aryl ether toward pyrazolemethylene-substituted phosphinyl allenes enabled facile synthesis of combined motifs with pyrazole and allene. Moreover, the obtained adducts could be easily transformed to potential bioactive multifunctionalized phosphinates via a novel alkenyl C-P(O) cleavage.
authors.affiliation: Jiangsu Key Laboratory of Pesticide Science and Department of Chemistry, College of Sciences, Nanjing Agricultural University , Nanjing, China.
authors.forename: Jie
authors.initials: J
authors.lastname: Zhu
authors.affiliation: Jiangsu Key Laboratory of Pesticide Science and Department of Chemistry, College of Sciences, Nanjing Agricultural University , Nanjing, China.
authors.forename: Mao
authors.initials: M
authors.lastname: Mao
authors.affiliation: Jiangsu Key Laboratory of Pesticide Science and Department of Chemistry, College of Sciences, Nanjing Agricultural University , Nanjing, China.
authors.forename: Huan-Jing
authors.initials: HJ
authors.lastname: Ji
authors.affiliation: Jiangsu Key Laboratory of Pesticide Science and Department of Chemistry, College of Sciences, Nanjing Agricultural University , Nanjing, China.
authors.forename: Jiang-Yan
authors.initials: JY
authors.lastname: Xu
authors.affiliation: Jiangsu Key Laboratory of Pesticide Science and Department of Chemistry, College of Sciences, Nanjing Agricultural University , Nanjing, China.|Beijing National Laboratory for Molecular Sciences and Institute of Chemistry, Chinese Academy of Sciences , Beijing, P. R. China.
authors.forename: Lei
authors.identifier: 0000-0001-9130-6619
authors.initials: L
authors.lastname: Wu