title: Computed Tomography Findings of Bronchiectasis in Different Respiratory Phases Correlate with Pulmonary Function Test Data in Adults.
abstract: To investigate bronchiectasis variations in different computed tomography (CT) respiratory phases, and their correlation with pulmonary function test (PFT) data, in adults.
  
  
  
  Retrospective data analysis from 63 patients with bronchiectasis according to CT criteria selected from the institution database and for whom PFT data were also available. Bronchiectasis diameter was measured on inspiratory and expiratory phases. Its area and matched airway-vessel ratios in both phases were also calculated. Finally, PFT results were compared with radiological measurements.
  
  
  
  Bronchiectatic airways were larger on inspiration than on expiration (mean cross-sectional area, 69.44 vs. 40.84 mm2; p < 0.05) as were airway-vessel ratios (2.1 vs. 1.4; p < 0.05). Cystic bronchiectasis cases showed the least variation in cross-sectional area (48%). Mean predicted values of forced expiratory volume in 1 s (FEV1) and forced vital capacity (FVC) were 81.5 and 77.2%, respectively, in the group in which bronchiectasis could not be identified on expiratory images, and 58.3 and 56.0%, respectively, in the other group (p < 0.05). Variation in bronchiectasis area was associated with poorer lung function (r = 0.32).
  
  
  
  Bronchiectasis detection, diameter, and area varied significantly according to CT respiratory phase, with non-reducible bronchiectasis showing greater lung function impairment.
authors.affiliation: LABIMED - Medical Imaging Research Laboratoy of Federal University of Health Sciences of Porto Alegre and Santa Casa de Misericordia de Porto Alegre Hospitals, 295 Professor Annes Dias St., Centro Histórico, Porto Alegre, Rio Grande Do Sul, 90020-090, Brazil. rh.doamaral@gmail.com.
authors.forename: Ricardo Holderbaum
authors.initials: RH
authors.lastname: do Amaral
authors.affiliation: LABIMED - Medical Imaging Research Laboratoy of Federal University of Health Sciences of Porto Alegre and Santa Casa de Misericordia de Porto Alegre Hospitals, 295 Professor Annes Dias St., Centro Histórico, Porto Alegre, Rio Grande Do Sul, 90020-090, Brazil.
authors.forename: Carlos S
authors.initials: CS
authors.lastname: Nin
authors.affiliation: LABIMED - Medical Imaging Research Laboratoy of Federal University of Health Sciences of Porto Alegre and Santa Casa de Misericordia de Porto Alegre Hospitals, 295 Professor Annes Dias St., Centro Histórico, Porto Alegre, Rio Grande Do Sul, 90020-090, Brazil.
authors.forename: Vinicius V S
authors.initials: VVS
authors.lastname: de Souza
authors.affiliation: LABIMED - Medical Imaging Research Laboratoy of Federal University of Health Sciences of Porto Alegre and Santa Casa de Misericordia de Porto Alegre Hospitals, 295 Professor Annes Dias St., Centro Histórico, Porto Alegre, Rio Grande Do Sul, 90020-090, Brazil.
authors.forename: Giordano R T
authors.initials: GRT
authors.lastname: Alves
authors.affiliation: LABIMED - Medical Imaging Research Laboratoy of Federal University of Health Sciences of Porto Alegre and Santa Casa de Misericordia de Porto Alegre Hospitals, 295 Professor Annes Dias St., Centro Histórico, Porto Alegre, Rio Grande Do Sul, 90020-090, Brazil.
authors.forename: Edson
authors.initials: E
authors.lastname: Marchiori
authors.affiliation: LABIMED - Medical Imaging Research Laboratoy of Federal University of Health Sciences of Porto Alegre and Santa Casa de Misericordia de Porto Alegre Hospitals, 295 Professor Annes Dias St., Centro Histórico, Porto Alegre, Rio Grande Do Sul, 90020-090, Brazil.
authors.forename: Klaus
authors.initials: K
authors.lastname: Irion
authors.affiliation: LABIMED - Medical Imaging Research Laboratoy of Federal University of Health Sciences of Porto Alegre and Santa Casa de Misericordia de Porto Alegre Hospitals, 295 Professor Annes Dias St., Centro Histórico, Porto Alegre, Rio Grande Do Sul, 90020-090, Brazil.
authors.forename: Gustavo S P
authors.initials: GSP
authors.lastname: Meirelles
authors.affiliation: LABIMED - Medical Imaging Research Laboratoy of Federal University of Health Sciences of Porto Alegre and Santa Casa de Misericordia de Porto Alegre Hospitals, 295 Professor Annes Dias St., Centro Histórico, Porto Alegre, Rio Grande Do Sul, 90020-090, Brazil.
authors.forename: Bruno
authors.initials: B
authors.lastname: Hochhegger
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001987:Bronchiectasis / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D016208:Databases, Factual; D045853:Exhalation; D005260:Female; D005541:Forced Expiratory Volume; D006801:Humans; D001239:Inhalation; D008168:Lung / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D012119:Respiration; D012189:Retrospective Studies; D012720:Severity of Illness Index; D013147:Spirometry; D014057:Tomography, X-Ray Computed; D014797:Vital Capacity; D055815:Young Adult
keywords: Bronchiectasis; Computed tomography; Pulmonary disease; Pulmonary function test; Thorax