title: Management of Prosthetic Joint Infection.
abstract: Although uncommon, prosthetic joint infection is a devastating complication. This challenging condition requires a coordinated management approach to achieve good patient outcomes. This review details the general principles to consider when managing patients with prosthetic joint infection. The different medical/surgical treatment strategies and how to appropriately select a strategy are discussed. The data to support each strategy are presented, along with discussion of antimicrobial strategies in specific situations.
authors.affiliation: Division of Infectious Diseases, Department of Internal Medicine, Mayo Clinic, 200 1st Street Southwest, Rochester, MN 55905, USA. Electronic address: tande.aaron@mayo.edu.
authors.forename: Aaron J
authors.initials: AJ
authors.lastname: Tande
authors.affiliation: Division of Infectious Diseases, Department of Internal Medicine, Mayo Clinic, 200 1st Street Southwest, Rochester, MN 55905, USA.
authors.forename: Eric O
authors.initials: EO
authors.lastname: Gomez-Urena
authors.affiliation: Division of Infectious Diseases, Department of Internal Medicine, Mayo Clinic, 200 1st Street Southwest, Rochester, MN 55905, USA.
authors.forename: Elie F
authors.initials: EF
authors.lastname: Berbari
authors.affiliation: Division of Infectious Diseases, Department of Internal Medicine, Mayo Clinic, 200 1st Street Southwest, Rochester, MN 55905, USA.
authors.forename: Douglas R
authors.initials: DR
authors.lastname: Osmon
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001170:Arthritis, Infectious / Q000175:diagnosis / Q000188:drug therapy; D019643:Arthroplasty, Replacement / Q000009:adverse effects; D003646:Debridement; D019468:Disease Management; D006801:Humans; D017053:Infection Control / Q000379:methods*; D007595:Joint Prosthesis / Q000009:adverse effects*; D010019:Osteomyelitis / Q000188:drug therapy / Q000382:microbiology; D016459:Prosthesis-Related Infections / Q000188:drug therapy / Q000382:microbiology / Q000601:surgery / Q000628:therapy*
chemical_list: D000900:Anti-Bacterial Agents
keywords: 2-Stage exchange; Joint arthroplasty; Joint replacement; Osteomyelitis; Periprosthetic joint infection; Prosthetic joint infection; Septic arthritis