title: Development of TRPM8 Antagonists to Treat Chronic Pain and Migraine.
abstract: A review. Development of pharmaceutical antagonists of transient receptor potential melastatin 8 (TRPM8) have been pursued for the treatment of chronic pain and migraine. This review focuses on the current state of this progress.
authors.affiliation: Pacific University School of Physical Therapy, Hillsboro, OR 97123, USA. andy.weyer@pacificu.edu.
authors.forename: Andy D
authors.initials: AD
authors.lastname: Weyer
authors.affiliation: One Amgen Center Dr, Thousand Oaks, CA 91320, USA. slehto@amgen.com.
authors.forename: Sonya G
authors.initials: SG
authors.lastname: Lehto
keywords: cold analgesia; cold hyperalgesia; mechanical hyperalgesia; menthol; migraine; pain; transient receptor potential melastatin 8 (TRPM*)