title: Cholestatic Liver Diseases After Liver Transplant.
abstract: Primary sclerosing cholangitis (PSC) and primary biliary cholangitis (PBC) are the most common cholestatic liver diseases (CLD) in adults. Liver transplant (LT) is desirable for those who progress to end-stage liver disease. CLD have become an uncommon indication for LT. PSC and PBC accounted for 7.1% of all adult LT in 2015. CLD have the best post-LT outcomes compared with other indications for LT. Disease recurrence of PSC and PBC after LT is reported in up to 37% and 43% of LT recipients, respectively. Although recurrent PBC does not affect post-LT outcomes, recurrent PSC is associated with worse post-LT survival.
authors.affiliation: Division of Internal Medicine, Miller School of Medicine, University of Miami, 1611 Northwest 12th Avenue, Suite Central 600-D, Miami, FL 33136, USA.
authors.forename: Nathalie A
authors.initials: NA
authors.lastname: Pena Polanco
authors.affiliation: Division of Hepatology, Miller School of Medicine, University of Miami, 1120 Northwest 14th Street, Suite 1112, Miami, FL 33136, USA.
authors.forename: Cynthia
authors.initials: C
authors.lastname: Levy
authors.affiliation: Division of Hepatology, Miller School of Medicine, University of Miami, 1120 Northwest 14th Street, Suite 1112, Miami, FL 33136, USA. Electronic address: efm10@miami.edu.
authors.forename: Eric F
authors.initials: EF
authors.lastname: Martin
mesh_terms: D058625:End Stage Liver Disease / Q000601:surgery*; D006085:Graft Survival; D006801:Humans; D008105:Liver Cirrhosis, Biliary / Q000209:etiology*; D016031:Liver Transplantation / Q000009:adverse effects*; D011183:Postoperative Complications; D012008:Recurrence
keywords: Cholestatic liver disease; Liver transplant; Outcomes; Primary biliary cholangitis; Primary sclerosing cholangitis; Recurrence