title: Cardiac regeneration: All work and no repair?
abstract: Structural changes in the developing heart may influence the limited regenerative capacity of the adult heart. We examine how the workload exerted on the adult mammalian heart may limit regenerative capability and discuss recent therapies that demonstrate beneficial effects through unloading the heart.
authors.affiliation: National Heart and Lung Institute, Imperial College London, London W12 0NN, UK. teresa.kennedy-lydon@imperial.ac.uk.
authors.forename: Teresa
authors.identifier: 0000-0001-7394-0798
authors.initials: T
authors.lastname: Kennedy-Lydon
authors.affiliation: National Heart and Lung Institute, Imperial College London, London W12 0NN, UK.|Australian Regenerative Medicine Institute, Monash University, Melbourne, Victoria, Australia.|The Jackson Laboratory, Bar Harbor, ME, USA.
authors.forename: Nadia
authors.initials: N
authors.lastname: Rosenthal
mesh_terms: D000818:Animals; D048430:Cell Shape; D006321:Heart / Q000254:growth & development / Q000502:physiology*; D006801:Humans; D009206:Myocardium / Q000166:cytology / Q000378:metabolism; D012038:Regeneration / Q000502:physiology*