title: Endovascular Therapy for Acute Stroke.
abstract: Stroke is the most common cause of permanent disability, the second most common cause of dementia, and the fourth most common cause of death in the Western world. Recently, based on positive multicenter randomized clinical trials, endovascular therapy for acute stroke has undergone a revolution. Routine mechanical thrombectomy in addition to intravenous thrombolysis has been shown to provide excellent outcomes for patients with proximal anterior circulation occlusions. This procedure reduces disability and benefits are seen across a wide range of age and initial stroke severity. Important features that affect treatment decisions include time of presentation, the patient's clinical status, imaging characteristics, and lab tests. Under optimal conditions, it should be available to patients 24/7, similar to systems offering prompt percutaneous coronary interventions to patients with acute ST-segment elevation myocardial infarctions.
authors.affiliation: Clinic for Diagnostic and Interventional Neuroradiology, Hospital Bremen-Mitte.
authors.forename: Maria
authors.initials: M
authors.lastname: Politi
authors.affiliation: Clinic for Neurology, Hospital Bremen-Mitte.
authors.forename: Andreas
authors.initials: A
authors.lastname: Kastrup
authors.affiliation: Pepin Heart Institute Florida Hospital, Tampa, FL; University of Missouri, Columbia, MΟ.
authors.forename: Konstantinos
authors.initials: K
authors.lastname: Marmagkiolis
authors.affiliation: Neuroscience and Vascular Simulation Unit, Anglia Ruskin University, Essex, UK.
authors.forename: Iris Q
authors.initials: IQ
authors.lastname: Grunwald
authors.affiliation: Clinic for Diagnostic and Interventional Neuroradiology, Hospital Bremen-Mitte; Neuroscience and Vascular Simulation Unit, Anglia Ruskin University, Essex, UK. Electronic address: papanagiotou@me.com.
authors.forename: Panagiotis
authors.initials: P
authors.lastname: Papanagiotou
mesh_terms: D003362:Cost-Benefit Analysis; D004185:Disability Evaluation; D057510:Endovascular Procedures / Q000009:adverse effects / Q000191:economics / Q000379:methods; D017048:Health Care Costs; D006801:Humans; D020127:Recovery of Function; D020521:Stroke / Q000175:diagnosis / Q000191:economics / Q000503:physiopathology / Q000628:therapy*; D013997:Time Factors; D016896:Treatment Outcome
keywords: Cerebral arterial disease; Endovascular therapy; Stroke