title: Vaccine Associated Paralytic Poliomyelitis Unmasking Common Variable Immunodeficiency.
abstract: BACKGROUND
  Oral polio vaccine can rarely lead to Vaccine-associated paralytic poliomyelitis (VAPP).
  
  
  METHODS
  A 2-year-old child with asymmetric paralysis of lower limbs following first booster of oral polio vaccine; type 2 Vaccine-derived poliovirus (VDPV) isolated. Subsequently, the child was diagnosed to have common variable immunodeficiency.
  
  
  RESULTS
  Paralysis gradually improved on follow-up; monthly intravenous immunoglobulin therapy started for primary immunodeficiency.
  
  
  CONCLUSIONS
  We need to evaluate children with VAPP for underlying immunodeficiency.
authors.affiliation: Department of Pediatrics, University College of Medical Sciences and Guru Teg Bahadur Hospital, Dilshad Garden, Delhi 110095, India. Correspondence to: Dr Sunil Gomber, Director-Professor, Department of Pediatrics, Guru Teg Bahadur Hospital, Dilshad Garden. Delhi 110 095, India. sunilgomber@hotmail.com.
authors.forename: Sunil
authors.initials: S
authors.lastname: Gomber
authors.forename: Vanny
authors.initials: V
authors.lastname: Arora
authors.forename: Pooja
authors.initials: P
authors.lastname: Dewan
mesh_terms: D002675:Child, Preschool; D017074:Common Variable Immunodeficiency / Q000175:diagnosis*; D005243:Feces / Q000821:virology; D005260:Female; D006801:Humans; D010243:Paralysis / Q000821:virology; D011051:Poliomyelitis; D011055:Poliovirus Vaccine, Oral / Q000009:adverse effects*
chemical_list: D011055:Poliovirus Vaccine, Oral