title: Synthesis and mechanical properties of double cross-linked gelatin-graphene oxide hydrogels.
abstract: Gelatin is an interesting biological macromolecule for biomedical applications. Here, double cross-linked gelatin nanocomposite hydrogels with incorporation of graphene oxide (GO) were synthesized in one pot using glutaraldehyde (GTA) and GTA-grafted GO as double chemical cross-linkers. The nanocomposite hydrogels, in contrast to the neat gelatin hydrogel, exhibited significant increases in mechanical properties by up to 288% in compressive strength, 195% in compressive modulus, 267% in compressive fracture energy and 160% shear storage modulus with the optimal GO concentration. Fourier transform infrared spectroscopy, scanning electron microscopy and swelling tests were implemented to characterize the nanocomposite hydrogels.
authors.affiliation: Department of Materials Science and Engineering, University of Sheffield, Mappin Street, Sheffield S1 3JD, United Kingdom.
authors.forename: Yongzhe
authors.initials: Y
authors.lastname: Piao
authors.affiliation: Department of Materials Science and Engineering, University of Sheffield, Mappin Street, Sheffield S1 3JD, United Kingdom. Electronic address: biqiong.chen@sheffield.ac.uk.
authors.forename: Biqiong
authors.initials: B
authors.lastname: Chen
mesh_terms: D060326:Chemistry Techniques, Synthetic; D005780:Gelatin / Q000737:chemistry*; D005976:Glutaral / Q000737:chemistry; D006108:Graphite / Q000737:chemistry*; D020100:Hydrogels / Q000138:chemical synthesis* / Q000737:chemistry*; D055595:Mechanical Phenomena; D010087:Oxides / Q000737:chemistry*
chemical_list: D020100:Hydrogels; D010087:Oxides; D006108:Graphite; D005780:Gelatin; D005976:Glutaral
keywords: Gelatin; Graphene oxide; Mechanical properties; Nanocomposite hydrogel