title: The Roles of Opioid Receptors in Cutaneous Wound Healing.
abstract: The process of recovery from skin wounding can be protracted and painful, and scarring may lead to weakness of the tissue, unpleasant sensations such as pain or itch, and unfavorable cosmetic outcomes. Moreover, some wounds simply fail to heal and become a chronic burden for the sufferer. Understanding the mechanisms underlying wound healing and the concomitant sensory disorders and how they might be manipulated for therapeutic benefit has attracted much interest in recent years, and here we discuss the latest developments in the field, focusing on the emergent roles of the peripheral opioid receptor (OPr) system.
authors.affiliation: Experimental Dermatology Group, Institute of Medical Biology, A*STAR, Singapore, Singapore, 138648. qimei1@gmail.com.
authors.forename: Mei
authors.initials: M
authors.lastname: Bigliardi-Qi
authors.affiliation: NUH/NUS, National University Hospital/National University of Singapore, Singapore, Singapore, 119228.|Experimental Dermatology Group, Institute of Medical Biology, A*STAR, Singapore, Singapore, 138648.
authors.forename: Paul
authors.initials: P
authors.lastname: Bigliardi
mesh_terms: D000818:Animals; D049109:Cell Proliferation; D006801:Humans; D007249:Inflammation / Q000473:pathology; D017465:Receptors, Opioid, delta / Q000378:metabolism* / Q000502:physiology*; D012867:Skin / Q000293:injuries* / Q000378:metabolism* / Q000473:pathology; D014945:Wound Healing / Q000502:physiology*
chemical_list: D017465:Receptors, Opioid, delta
keywords: Opioid receptors; Skin; Wound healing