title: Cardiomyopathy in Patients With Hereditary Bullous Epidermolysis.
abstract: OBJECTIVE
  In recent decades, an association has been reported between epidermolysis bullosa (EB) and dilated cardiomyopathy (DC). DC is typically in an advanced phase when detected, leading to a poorer prognosis. Our objective was to determine the prevalence of DC in patients with EB seen in Hospital San Joan de Déu in Barcelona, Spain, between May 1986 and April 2015.
  
  
  METHODS
  This was a descriptive, cross-sectional chart-review study in which we recorded the type and main subtypes of EB and the presence or absence of DC.
  
  
  RESULTS
  Fifty-seven patients with EB were found, 19 with EB simplex, 10 with junctional EB, 27 with dystrophic EB (14 dominant dystrophic and 13 recessive dystrophic), and just 1 with Kindler syndrome. DC was detected in only 2 patients with recessive dystrophic EB. Twenty-three patients had presented factors that could have had a causal relationship with the potential onset of DC.
  
  
  CONCLUSIONS
  DC is a possible complication of EB, particularly in recessive dystrophic EB. Periodic follow-up should be performed to make an early diagnosis and start treatment.
authors.affiliation: Servicio de Dermatología, Hospital Sant Joan de Déu, Barcelona, España.
authors.forename: A
authors.initials: A
authors.lastname: Batalla
authors.affiliation: Servicio de Dermatología, Hospital Sant Joan de Déu, Barcelona, España. Electronic address: avicente@hsjdbcn.org.
authors.forename: A
authors.initials: A
authors.lastname: Vicente
authors.affiliation: Servicio de Cardiología, Hospital Sant Joan de Déu, Barcelona, España.
authors.forename: J
authors.initials: J
authors.lastname: Bartrons
authors.affiliation: Servicio de Cardiología, Hospital Sant Joan de Déu, Barcelona, España.
authors.forename: F
authors.initials: F
authors.lastname: Prada
authors.affiliation: Servicio de Pediatría, Hospital Sant Joan de Déu, Barcelona, España.
authors.forename: C
authors.initials: C
authors.lastname: Fortuny
authors.affiliation: Servicio de Dermatología, Hospital Sant Joan de Déu, Barcelona, España.
authors.forename: M A
authors.initials: MA
authors.lastname: González-Enseñat
mesh_terms: D000293:Adolescent; D000740:Anemia / Q000150:complications; D009202:Cardiomyopathies / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000209:etiology*; D015984:Causality; D002648:Child; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D042241:Early Diagnosis; D004820:Epidermolysis Bullosa / Q000145:classification / Q000150:complications* / Q000235:genetics; D016108:Epidermolysis Bullosa Dystrophica / Q000150:complications / Q000235:genetics; D005260:Female; D006801:Humans; D008297:Male; D015995:Prevalence; D011379:Prognosis; D012307:Risk Factors; D014777:Virus Diseases / Q000150:complications
keywords: Dilated cardiomyopathy; Echocardiography; Ecocardiograma; Epidermolysis bullosa; Epidermólisis ampollosa; Micronutrientes; Micronutrients; Miocardiopatía dilatada