title: Molecular Characterization of Escherichia coli Isolates Carryingmcr-1,fosA3, and Extended-Spectrum-β-Lactamase Genes from Food Samples in China.
abstract: This study surveyed the prevalence ofmcr-1in extended-spectrum-β-lactamase (ESBL)-producingEscherichia colistrains of food origin in China and identified strains that carriedmcr-1,fosA3, and ESBL genes, which were carried in various plasmids. Themcr-1and ESBL genes could be cotransferred by one or more types of plasmids. The presence of these multidrug-resistantE. colistrains in food products might pose a huge threat to public health.
authors.affiliation: College of Food Science and Engineering, Northwest A&F University, Yangling, Shaanxi, China.|Shenzhen Key Lab for Food Biological Safety Control, Food Safety and Technology Research Center, Hong Kong PolyU Shenzhen Research Institute, Shenzhen, China.
authors.forename: Xiaobo
authors.initials: X
authors.lastname: Liu
authors.affiliation: Shenzhen Key Lab for Food Biological Safety Control, Food Safety and Technology Research Center, Hong Kong PolyU Shenzhen Research Institute, Shenzhen, China.|The State Key Lab of Chirosciences, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, SAR.
authors.forename: Ruichao
authors.initials: R
authors.lastname: Li
authors.affiliation: College of Food Science and Engineering, Northwest A&F University, Yangling, Shaanxi, China.|Shenzhen Key Lab for Food Biological Safety Control, Food Safety and Technology Research Center, Hong Kong PolyU Shenzhen Research Institute, Shenzhen, China.
authors.forename: Zhiwei
authors.initials: Z
authors.lastname: Zheng
authors.affiliation: Shenzhen Key Lab for Food Biological Safety Control, Food Safety and Technology Research Center, Hong Kong PolyU Shenzhen Research Institute, Shenzhen, China.|The State Key Lab of Chirosciences, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, SAR.
authors.forename: Kaichao
authors.initials: K
authors.lastname: Chen
authors.affiliation: Shenzhen Key Lab for Food Biological Safety Control, Food Safety and Technology Research Center, Hong Kong PolyU Shenzhen Research Institute, Shenzhen, China.|The State Key Lab of Chirosciences, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, SAR.
authors.forename: Miaomiao
authors.initials: M
authors.lastname: Xie
authors.affiliation: The State Key Lab of Chirosciences, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, SAR.
authors.forename: Edward Wai-Chi
authors.initials: EW
authors.lastname: Chan
authors.affiliation: College of Food Science and Engineering, Northwest A&F University, Yangling, Shaanxi, China sgeng@ucdavis.edu sheng.chen@polyu.edu.hk.
authors.forename: Shu
authors.initials: S
authors.lastname: Geng
authors.affiliation: Shenzhen Key Lab for Food Biological Safety Control, Food Safety and Technology Research Center, Hong Kong PolyU Shenzhen Research Institute, Shenzhen, China sgeng@ucdavis.edu sheng.chen@polyu.edu.hk.|The State Key Lab of Chirosciences, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, SAR.
authors.forename: Sheng
authors.initials: S
authors.lastname: Chen
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology; D002681:China; D004269:DNA, Bacterial / Q000235:genetics; D024901:Drug Resistance, Multiple, Bacterial / Q000235:genetics; D004926:Escherichia coli / Q000187:drug effects* / Q000235:genetics* / Q000302:isolation & purification; D029968:Escherichia coli Proteins / Q000235:genetics*; D005506:Food Contamination; D005517:Foodborne Diseases / Q000382:microbiology; D016680:Genome, Bacterial / Q000235:genetics; D008826:Microbial Sensitivity Tests; D010957:Plasmids / Q000235:genetics; D000069466:Red Meat / Q000382:microbiology; D017747:Seafood / Q000382:microbiology; D001618:beta-Lactamases / Q000235:genetics*; D047090:beta-Lactams / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D004269:DNA, Bacterial; D029968:Escherichia coli Proteins; C000607929:FosA(3) protein, E coli; C000614037:MCR-1 protein, E coli; D047090:beta-Lactams; D001618:beta-Lactamases
keywords: ESBL-producing E. coli; Tn6330; circular intermediate; fosA3; mcr-1; plasmids; transmission