title: Amlodipine as an antiischemic drug is superior to long acting nitrates.
abstract: European Society of Cardiology Guidelines cite results of meta-analysis that the use of calcium channel blockers results in fewer angina episodes per week vs. long-acting nitrates. Moreover, we listed 12 reasons more to prefer amlodipine over long-acting nitrates, especially in stable angina pectoris patients with arterial hypertension. It may be the way to decrease polypharmacy without loosing efficacy. Some important advantages of amlodipine versus long-acting nitrate(s) are: amlodipine also treats hypertension, it helps reducing hypertensive target organ damages (e.g. left ventricular hypertrophy) and prevents morning blood pressure surge. Moreover, amlodipine can be given once daily (which improves adherence), it produces neither tolerance nor rebound, it has less side effects.
authors.affiliation: Department for Cardiovascular Diseases, Clinical center Niš, Bulevar Dr Z. Djindjića 48, 18000 Niš, Serbia, Medical Faculty, University of Niš, Bulevar Dr Zorana Djindjića 81, 18 000 Niš, Serbia.
authors.forename: Goran P
authors.initials: GP
authors.lastname: Koraćević
authors.affiliation: Department for Cardiovascular Diseases, Clinical center Niš, Bulevar Dr Z. Djindjića 48, 18000 Niš, Serbia.
authors.forename: Sonja S
authors.initials: SS
authors.lastname: Dakić
authors.affiliation: Medical Faculty, University of Niš, Bulevar Dr Zorana Djindjića 81, 18 000 Niš, Serbia Department of Clinical Pharmacology, Clinical center Niš, Bulevar Dr Zorana Djindjića 48, 18 000 Serbia.
authors.forename: Radmila M
authors.initials: RM
authors.lastname: Veličković-Radovanović
authors.affiliation: Department for Cardiovascular Diseases, Clinical center Niš, Bulevar Dr Z. Djindjića 48, 18000 Niš, Serbia, Medical Faculty, University of Niš, Bulevar Dr Zorana Djindjića 81, 18 000 Niš, Serbia.
authors.forename: Svetlana R
authors.initials: SR
authors.lastname: Apostolović
authors.affiliation: Department for Cardiovascular Diseases, Clinical center Niš, Bulevar Dr Z. Djindjića 48, 18000 Niš, Serbia.
authors.forename: Nebojša H
authors.initials: NH
authors.lastname: Krstić
authors.affiliation: Department for Cardiovascular Diseases, Clinical center Niš, Bulevar Dr Z. Djindjića 48, 18000 Niš, Serbia Institute for therapy and prevention Niška Banja, Srpskih junaka 2, 18 205 Niška Banja, Serbia.
authors.forename: Ivan S
authors.initials: IS
authors.lastname: Tasić
authors.affiliation: Clinical Hospital Center Bežanijska kosa, Faculty of Medicine, Univesirty of Belgrade, Bežanijska kosa bb, 11 000 Belgrade, Serbia.
authors.forename: Marija D
authors.initials: MD
authors.lastname: Zdravković
authors.affiliation: School of Medicine, Belgrade, Clinic of Cardiology, Clinical Centre of Serbia, Pasterova 2, 11 000 Belgrade, Serbia.
authors.forename: Nebojša M
authors.initials: NM
authors.lastname: Antonijević
authors.affiliation: Military Hospital Niš, Bulevar Dr Zorana Đinđića bb, 18 000 Niš, Serbia.
authors.forename: Goran N
authors.initials: GN
authors.lastname: Damnjanović
authors.affiliation: Department for Cardiovascular Diseases, Clinical center Niš, Bulevar Dr Z. Djindjića 48, 18000 Niš, Serbia.
authors.forename: Tomislav L
authors.initials: TL
authors.lastname: Kostić
keywords: Amlodipine; Long acting nitrates; Stable angina pectoris