title: [Diagnostic Accuracy of German Depression Screenings in Patients with Coronary Heart Disease].
abstract: To compare the diagnostic accuracy of German depression screening instruments in patients with coronary heart disease (CHD).
  
  
  
  1019 CHD patients completed the Patient Health Questionnaire (PHQ-9 and PHQ-2) and the Hospital Anxiety and Depression Scale (HADS-D). The Composite International Diagnostic Interview served as reference standard for "any depressive disorder" and "major depression".
  
  
  
  The accuracy of the PHQ-9 and the HADS-D was comparable according to the area under the curve, and both were superior to the PHQ-2. The optimal cut-off according to the Youden index (maximum sum of sensitivity and specificity) was 7 for both instruments. At this optimal cut-off, the PHQ-9 had a higher sensitivity compared to the HADS-D, but a lower specificity (below 68). Results remained similar when patients who reported that they currently underwent treatment for depression were excluded.
  
  
  
  The PHQ-9 and the HADS-D have comparable overall diagnostic accuracy in CHD patients. In line with previous screening studies with CHD patients, the optimal cut-offs were below the cut-offs that are recommended in the literature.
authors.affiliation: Klinik für Psychiatrie und Psychotherapie, Charité - Universitätsmedizin Berlin.|Sozial- und Präventivmedizin, Strukturbereich Kognitionswissenschaften, Department Sport- und Gesundheitswissenschaften, Universität Potsdam.
authors.forename: Mira
authors.initials: M
authors.lastname: Tschorn
authors.affiliation: Institut für Public Health, Charité - Universitätsmedizin Berlin.
authors.forename: Nina
authors.initials: N
authors.lastname: Rieckmann
authors.affiliation: Klinik für Psychiatrie und Psychotherapie, Universitätsklinikum Münster.
authors.forename: Volker
authors.initials: V
authors.lastname: Arolt
authors.affiliation: Klinik für Psychiatrie und Psychotherapie, Charité - Universitätsmedizin Berlin.
authors.forename: Katja
authors.initials: K
authors.lastname: Beer
authors.affiliation: Medizinische Klinik mit Schwerpunkt Kardiologie, Charité - Universitätsmedizin Berlin.
authors.forename: Wilhelm
authors.initials: W
authors.lastname: Haverkamp
authors.affiliation: Institut für Klinische Epidemiologie und angewandte Biometrie, Universitätsklinikum Tübingen.
authors.forename: Peter
authors.initials: P
authors.lastname: Martus
authors.affiliation: Department für Kardiologie und Angiologie, Universitätsklinikum Münster.
authors.forename: Johannes
authors.initials: J
authors.lastname: Waltenberger
authors.affiliation: Institut für Public Health, Charité - Universitätsmedizin Berlin.
authors.forename: Jacqueline
authors.initials: J
authors.lastname: Müller-Nordhorn
authors.affiliation: Klinik für Psychiatrie und Psychotherapie, Charité - Universitätsmedizin Berlin.
authors.forename: Andreas
authors.initials: A
authors.lastname: Ströhle
mesh_terms: D003327:Coronary Disease / Q000523:psychology; D003863:Depression / Q000175:diagnosis* / Q000209:etiology; D005858:Germany; D006801:Humans; D008403:Mass Screening; D011569:Psychiatric Status Rating Scales; D011594:Psychometrics / Q000379:methods / Q000592:standards*; D015203:Reproducibility of Results; D011795:Surveys and Questionnaires