title: Validity of premature ejaculation diagnostic tool and its association with International Index of Erectile Function-15 in Chinese men with evidence-based-defined premature ejaculation.
abstract: The premature ejaculation diagnostic tool (PEDT) is a brief diagnostic measure to assess premature ejaculation (PE). However, there is insufficient evidence regarding its validity in the new evidence-based-defined PE. This study was performed to evaluate the validity of PEDT and its association with IIEF-15 in different types of evidence-based-defined PE. From June 2015 to January 2016, a total of 260 men complaining of PE and defined as lifelong PE (LPE)/acquired PE (APE) according to the evidence-based definition from Andrology Clinic of the First Affiliated Hospital of Anhui Medical University, along with 104 male healthy controls without PE from a medical examination center, were enrolled in this study. All individuals completed questionnaires including demographics, medical and sexual history, as well as PEDT and IIEF-15. After statistical analysis, it was found that men with PE reported higher PEDT scores (14.28 ± 3.05) and lower IIEF-15 (41.26 ± 8.20) than men without PE (PEDT: 5.32 ± 3.42, IIEF-15: 52.66 ± 6.86, P < 0.001 for both). It was suggested that a score of ≥9 indicated PE in both LPE and APE by sensitivity and specificity analyses (sensitivity: 0.875, 0.913; specificity: 0.865, 0.865, respectively). In addition, IIEF-15 were higher in men with LPE (42.64 ± 8.11) than APE (39.43 ± 7.84, P < 0.001). After adjusting for age, IIEF-15 was negatively related to PEDT in men with LPE (adjust r = -0.225, P < 0.001) and APE (adjust r = -0.378, P < 0.001). In this study, we concluded that PEDT was valid in the diagnosis of evidenced-based-defined PE. Furthermore, IIEF-15 was negatively related to PEDT in men with different types of PE.
authors.affiliation: Department of Urology, The First Affiliated Hospital of Anhui Medical University, Hefei, China.|Reproductive Medicine Center, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
authors.forename: Dong-Dong
authors.initials: DD
authors.lastname: Tang
authors.affiliation: Department of Urology, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
authors.forename: Chao
authors.initials: C
authors.lastname: Li
authors.affiliation: Department of Urology, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
authors.forename: Dang-Wei
authors.initials: DW
authors.lastname: Peng
authors.affiliation: Department of Urology, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
authors.forename: Xian-Sheng
authors.initials: XS
authors.lastname: Zhang
mesh_terms: D000328:Adult; D000375:Aging; D044466:Asian People; D007172:Erectile Dysfunction / Q000175:diagnosis*; D019317:Evidence-Based Medicine; D005260:Female; D006801:Humans; D008297:Male; D061686:Premature Ejaculation / Q000175:diagnosis*; D012016:Reference Values; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D012959:Socioeconomic Factors; D011795:Surveys and Questionnaires; D055815:Young Adult