title: Trace determination of organophosphate esters in white wine, red wine, and beer samples using dispersive liquid-liquid microextraction combined with ultra-high-performance liquid chromatography-tandem mass spectrometry.
abstract: In this study, dispersive liquid-liquid microextraction coupled with ultra-high-performance liquid chromatography-tandem mass spectrometry was developed for the analysis of five representative organophosphate esters (OPEs) in wine samples. Under optimized conditions, the proposed method resulted in good linearity (R2>0.9933) over the range of 0.1-100μgL-1, with limits of detection (LODs, S/N =3) and quantification (LOQs, S/N =10) in the ranges of 0.48-18.8ngL-1and 1.58-62.5ngL-1, respectively. Inter- and intra-assay precisions of RSD% ranged from 3.21% to 6.13% and from 1.69% to 7.63%, respectively. The spiked recoveries of target OPEs from white wine, red wine, and beer samples were in the ranges of 80-122%, 76-120%, and 76-110%, respectively, at two different concentration levels. The total concentrations of five OPEs found in white wine, red wine, and beer samples were in the ranges of 0.29-0.85μgL-1, 1.00-3.05μgL-1, and 0.86-1.47μgL-1, respectively.
authors.affiliation: Department of Material and Chemical Engineering, Zhengzhou University of Light Industry, Zhengzhou, Henan 450001, People's Republic of China; Collaborative Innovation Center of Environmental Pollution Control and Ecological Restoration, Zhengzhou, Henan 450001, People's Republic of China. Electronic address: lpang@zzuli.edu.cn.
authors.forename: Long
authors.initials: L
authors.lastname: Pang
authors.affiliation: Department of Material and Chemical Engineering, Zhengzhou University of Light Industry, Zhengzhou, Henan 450001, People's Republic of China.
authors.forename: Huiqiang
authors.initials: H
authors.lastname: Yang
authors.affiliation: Department of Material and Chemical Engineering, Zhengzhou University of Light Industry, Zhengzhou, Henan 450001, People's Republic of China.
authors.forename: Peijie
authors.initials: P
authors.lastname: Yang
authors.affiliation: Department of Material and Chemical Engineering, Zhengzhou University of Light Industry, Zhengzhou, Henan 450001, People's Republic of China; Collaborative Innovation Center of Environmental Pollution Control and Ecological Restoration, Zhengzhou, Henan 450001, People's Republic of China. Electronic address: zhz@zzuli.edu.cn.
authors.forename: Hongzhong
authors.initials: H
authors.lastname: Zhang
authors.affiliation: Collaborative Innovation Center of Environmental Pollution Control and Ecological Restoration, Zhengzhou, Henan 450001, People's Republic of China.
authors.forename: Jihong
authors.initials: J
authors.lastname: Zhao
mesh_terms: D001515:Beer / Q000032:analysis*; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D004952:Esters / Q000032:analysis; D005506:Food Contamination / Q000032:analysis; D057230:Limit of Detection; D059627:Liquid Phase Microextraction / Q000379:methods*; D010755:Organophosphates / Q000032:analysis*; D053719:Tandem Mass Spectrometry / Q000379:methods*; D014920:Wine / Q000032:analysis*
chemical_list: D004952:Esters; D010755:Organophosphates
keywords: Beer; Dispersive liquid-liquid microextraction; Organophosphate esters; Red wine; Ultra-high-performance liquid chromatography–tandem mass spectrometry; White wine