title: Integrated therapeutic approach to giant solitary fibrous tumor of the pleura: report of a case and review of the literature.
abstract: The fibrous tumors of the pleura are rare primary tumors, accounting for 5% of malignant pleural neoplasms, which generally originate from sub-mesothelial mesenchymal tissue of the visceral pleura. These tumours generally exhibit clinical benign behavior although 12% of solitary fibrous tumors can be malignant and have worse outcomes. These tumors are considered "giant" when the lesion > 15 cm. Surgical treatment is the best choice for both benign and malignant neoplasms. We retrospectively analyzed the main case series of giant fibrous tumors of the pleura. In addition we report our experience of a 76-year-old woman treated by pre-surgical embolization involving implantation of vascular plugs. Surgery was successfully carried out without complications; imaging and functional assessment 6 months post intervention demonstrated both the absence of recurrence and improvement of lung function parameters.
authors.affiliation: Department of Cardiotho-racic and Respiratory Sciences, Second University of Naples/Hosp. Monaldi, Naples, Italy.
authors.forename: Fabio
authors.initials: F
authors.lastname: Perrotta
authors.affiliation: Department of Cardiothoracic and Respiratory Sciences, Second University of Naples/Hosp. Monaldi, Naples, Italy.
authors.forename: Francesco Saverio
authors.initials: FS
authors.lastname: Cerqua
authors.affiliation: Department of Cardiothoracic and Respiratory Sciences, Second University of Naples/Hosp. Monaldi, Naples, Italy.
authors.forename: Antonino
authors.initials: A
authors.lastname: Cammarata
authors.affiliation: Department of Cardiothoracic and Respiratory Sciences, Second University of Naples/Hosp. Monaldi, Naples, Italy.
authors.forename: Alessandro
authors.initials: A
authors.lastname: Izzo
authors.affiliation: A.O. dei Colli - Hosp. Monaldi - Thoracic Surgery Unit, Naples, Italy.
authors.forename: Carlo
authors.initials: C
authors.lastname: Bergaminelli
authors.affiliation: A.O. dei Colli - Hosp. Monaldi - Thoracic Surgery Unit, Naples, Italy.
authors.forename: Carlo
authors.initials: C
authors.lastname: Curcio
authors.affiliation: A.O. dei Colli - Hosp. Monaldi - Bronchology Unit, Naples, Italy.
authors.forename: Carmine
authors.initials: C
authors.lastname: Guarino
authors.affiliation: Department of Cardiothoracic and Respiratory Sciences, Second University of Naples/Hosp. Monaldi, Naples, Italy.
authors.forename: Edoardo
authors.initials: E
authors.lastname: Grella
authors.affiliation: Department of Cardiothoracic and Respiratory Sciences, Second University of Naples/Hosp. Monaldi, Naples, Italy.
authors.forename: Imma
authors.initials: I
authors.lastname: Forzano
authors.affiliation: Department of Cardiothoracic and Respiratory Sciences, Second University of Naples/Hosp. Monaldi, Naples, Italy.
authors.forename: Antonio
authors.initials: A
authors.lastname: Cennamo
authors.affiliation: Department of Sport Sciences and Wellness, University of Naples "Parthenope", Naples, Italy.
authors.forename: Domenico
authors.initials: D
authors.lastname: Tafuri
authors.affiliation: Department of Medicine and Health Sciences "Vincenzo Tiberio", University of Molise, Campobasso, Italy.
authors.forename: Aldo
authors.initials: A
authors.lastname: Rocca
authors.affiliation: Department of Cardiothoracic and Respiratory Sciences, Second University of Naples/Hosp. Monaldi, Naples, Italy.
authors.forename: Andrea
authors.initials: A
authors.lastname: Bianco
authors.affiliation: Department of Cardiothoracic and Respiratory Sciences, Second University of Naples/Hosp. Monaldi, Naples, Italy.
authors.forename: Gennaro
authors.initials: G
authors.lastname: Mazzarella
keywords: Embolization; Giant tumors; Solitary fibrous tumor of the pleura (SFTP); Surgical treatment