title: Safety and Effectiveness of Robot-Assisted Versus Open Radical Cystectomy for Bladder Cancer: A Systematic Review and Meta-Analysis.
abstract: OBJECTIVE
  To evaluate the safety and effectiveness of robot-assisted radical cystectomy (RARC) compared with open radical cystectomy (ORC) in bladder cancer.
  
  
  METHODS
  A literature search for the systematic review was conducted using international databases as well as domestic databases up to April 2015. Outcomes of interest included baseline characteristics, complication rates, perioperative, and oncologic outcomes.
  
  
  RESULTS
  Twenty-four articles were finally selected for inclusion in the meta-analysis. Complication rates of RARC were similar to those of ORC, except for 90-day overall complication rate, wound dehiscence, abscess, pneumonia, respiratory failure, and sepsis, which was lower after RARC. RARC was also associated with a smaller amount of estimated blood loss, lower transfusion rate, shorter length of hospital stay, shorter time to flatus, and more lymph node yield, whereas ORC was associated with a shorter operation time and lower rate of stricture. Considering oncologic outcomes, there were no differences between RARC and ORC.
  
  
  CONCLUSIONS
  RARC seems to be associated with equivalent complication rates, a smaller amount of estimated blood loss, lower transfusion rate, shorter length of hospital stay, shorter time to flatus, and more lymph node yield. Randomized controlled trials with a large sample size and comparative studies with long-term follow-up data are warranted to assess our findings and the oncologic effectiveness of RARC.
authors.affiliation: 1 Division for Healthcare Technology Assessment Research, National Evidence-based Healthcare Collaborating Agency, Seoul, Korea.|2 Department of Health Policy and Hospital Management, Graduate School of Public Health, Korea University , Seoul, Korea.
authors.forename: Soo Kyung
authors.initials: SK
authors.lastname: Son
authors.affiliation: 1 Division for Healthcare Technology Assessment Research, National Evidence-based Healthcare Collaborating Agency, Seoul, Korea.|2 Department of Health Policy and Hospital Management, Graduate School of Public Health, Korea University , Seoul, Korea.
authors.forename: Na Rae
authors.initials: NR
authors.lastname: Lee
authors.affiliation: 3 Department of Urology, College of Medicine, Korea University , Seoul, Korea.
authors.forename: Seok Ho
authors.initials: SH
authors.lastname: Kang
authors.affiliation: 4 Department of Nursing Science, College of Nursing, Gachon University , Incheon, Korea.
authors.forename: Seon Heui
authors.initials: SH
authors.lastname: Lee
mesh_terms: D015653:Cystectomy / Q000379:methods*; D006801:Humans; D007902:Length of Stay; D061646:Operative Time; D011183:Postoperative Complications; D065287:Robotic Surgical Procedures / Q000379:methods*; D016896:Treatment Outcome; D001749:Urinary Bladder Neoplasms / Q000601:surgery*
keywords: bladder cancer; cystectomy; robotics