title: Physiological protection of probiotic microcapsules by coatings.
abstract: Nowadays, food and nutrition have a greater impact in people's concerns, with the awareness that nutrition have a direct impact in health and wellbeing. Probiotics have an important role in this topic and consumers are starting to really understand their potential in health, leading to an increasing interest of the companies to their commercial use in foods. However, there are several limitations to the use of probiotics in foods and beverages, being one of them their efficiency (directly associated to their survival rate) upon ingestion. This work is focused in microencapsulation techniques that have been used to increase probiotics efficiency. More specifically, this work reviews the most recent and relevant research about the production and coating techniques of probiotic-loaded microcapsules, providing an insight in the effect of these coatings in probiotics survival during the gastrointestinal phase. This review shows that coatings with the better performances in probiotics protection, against the harsh conditions of digestion, are chitosan, alginate, poly-L-lysine, and whey protein. Chitosan presented an interesting performance in probiotics protection being able to maintain the initial concentration of viable probiotics during a digestive test. The analyses of different works also showed that the utilization of several coatings does not guarantee a better protection in comparison with monocoated microcapsules.
authors.affiliation: a Centre of Biological Engineering , University of Minho , Campus de Gualtar, Braga , Portugal.
authors.forename: Philippe E
authors.initials: PE
authors.lastname: Ramos
authors.affiliation: b International Iberian Nanotechnology Laboratory , Av. Mestre José Veiga s/n, Braga Portugal.
authors.forename: Miguel A
authors.initials: MA
authors.lastname: Cerqueira
authors.affiliation: a Centre of Biological Engineering , University of Minho , Campus de Gualtar, Braga , Portugal.
authors.forename: José A
authors.initials: JA
authors.lastname: Teixeira
authors.affiliation: a Centre of Biological Engineering , University of Minho , Campus de Gualtar, Braga , Portugal.
authors.forename: António A
authors.initials: AA
authors.lastname: Vicente
mesh_terms: D000464:Alginates / Q000737:chemistry; D002214:Capsules / Q000737:chemistry*; D048271:Chitosan / Q000737:chemistry; D004339:Drug Compounding; D005079:Excipients / Q000737:chemistry*; D006801:Humans; D050296:Microbial Viability; D011107:Polylysine / Q000737:chemistry; D011108:Polymers / Q000737:chemistry; D019936:Probiotics; D000067816:Whey Proteins / Q000737:chemistry
chemical_list: D000464:Alginates; D002214:Capsules; D005079:Excipients; D011108:Polymers; D000067816:Whey Proteins; D011107:Polylysine; D048271:Chitosan
keywords: Alginate; Chitosan; Emulsification; Extrusion; Layer-by-layer; Poly-L-lysine