title: Progressive telomere shortening is part of the natural history of chronic lymphocytic leukaemia and impacts clinical outcome: evidences from long term follow-up.
authors.affiliation: Department of Molecular Biotechnologies and Health Sciences, Division of Haematology, University of Torino, Torino, Italy.
authors.forename: Paola
authors.identifier: 0000-0001-6986-7954
authors.initials: P
authors.lastname: Ghione
authors.affiliation: Department of Molecular Biotechnologies and Health Sciences, Division of Haematology, University of Torino, Torino, Italy.
authors.forename: Elisa
authors.initials: E
authors.lastname: Genuardi
authors.affiliation: Department of Haematology, Oncology Institute of Southern Switzerland and Institute of Oncology Research, Bellinzona, Switzerland.
authors.forename: Davide
authors.initials: D
authors.lastname: Rossi
authors.affiliation: Department of Molecular Biotechnologies and Health Sciences, Division of Haematology, University of Torino, Torino, Italy.
authors.forename: Daniela
authors.initials: D
authors.lastname: Drandi
authors.affiliation: Department of Molecular Biotechnologies and Health Sciences, Division of Haematology, University of Torino, Torino, Italy.
authors.forename: Barbara
authors.initials: B
authors.lastname: Mantoan
authors.affiliation: Department of Molecular Biotechnologies and Health Sciences, Division of Haematology, University of Torino, Torino, Italy.
authors.forename: Daniela
authors.initials: D
authors.lastname: Barbero
authors.affiliation: Azienda Ospedaliera SS Antonio e Biagio e Cesare Arrigo, Alessandria, Italy.
authors.forename: Elisa
authors.initials: E
authors.lastname: Bernocco
authors.affiliation: Department of Molecular Biotechnologies and Health Sciences, Division of Haematology, University of Torino, Torino, Italy.
authors.forename: Luigia
authors.initials: L
authors.lastname: Monitillo
authors.affiliation: Division of Haematology, Department of Translational Medicine, Amedeo Avogadro University of Eastern Piedmont, Novara, Italy.
authors.forename: Michaela
authors.initials: M
authors.lastname: Cerri
authors.affiliation: Department of Molecular Biotechnologies and Health Sciences, Division of Haematology, University of Torino, Torino, Italy.
authors.forename: Marina
authors.initials: M
authors.lastname: Ruggeri
authors.affiliation: Department of Molecular Biotechnologies and Health Sciences, Division of Haematology, University of Torino, Torino, Italy.
authors.forename: Paola
authors.initials: P
authors.lastname: Omede
authors.affiliation: Division of Haematology, Department of Translational Medicine, Amedeo Avogadro University of Eastern Piedmont, Novara, Italy.
authors.forename: Clara
authors.initials: C
authors.lastname: Deambrogi
authors.affiliation: Division of Haematology, Department of Translational Medicine, Amedeo Avogadro University of Eastern Piedmont, Novara, Italy.
authors.forename: Lorenzo
authors.initials: L
authors.lastname: De Paoli
authors.affiliation: Nuclear Medicine, San Giovanni Battista Hospital and University of Torino, Torino, Italy.
authors.forename: Roberto
authors.initials: R
authors.lastname: Passera
authors.affiliation: Department of Molecular Biotechnologies and Health Sciences, Division of Haematology, University of Torino, Torino, Italy.
authors.forename: Marta
authors.initials: M
authors.lastname: Coscia
authors.affiliation: Department of Molecular Biotechnologies and Health Sciences, Division of Haematology, University of Torino, Torino, Italy.
authors.forename: Federica
authors.initials: F
authors.lastname: Cavallo
authors.affiliation: Department of Molecular Biotechnologies and Health Sciences, Division of Haematology, University of Torino, Torino, Italy.
authors.forename: Massimo
authors.initials: M
authors.lastname: Massaia
authors.affiliation: Department of Molecular Biotechnologies and Health Sciences, Division of Haematology, University of Torino, Torino, Italy.
authors.forename: Mario
authors.initials: M
authors.lastname: Boccadoro
authors.affiliation: Division of Haematology, Department of Translational Medicine, Amedeo Avogadro University of Eastern Piedmont, Novara, Italy.
authors.forename: Gianluca
authors.initials: G
authors.lastname: Gaidano
authors.affiliation: Azienda Ospedaliera SS Antonio e Biagio e Cesare Arrigo, Alessandria, Italy.
authors.forename: Marco
authors.initials: M
authors.lastname: Ladetto
authors.affiliation: Department of Molecular Biotechnologies and Health Sciences, Division of Haematology, University of Torino, Torino, Italy.
authors.forename: Simone
authors.initials: S
authors.lastname: Ferrero
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D018572:Disease-Free Survival; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000378:metabolism* / Q000401:mortality* / Q000473:pathology / Q000628:therapy; D008297:Male; D015996:Survival Rate; D016615:Telomere / Q000378:metabolism* / Q000473:pathology; D059505:Telomere Homeostasis
keywords: cell biology; chronic lymphocytic leukaemia; prognostic factors; telomere