title: Numerical simulation and identification of macroscopic vascularised liver behaviour: Case of indentation tests.
abstract: Mini-invasive surgery restricts the surgeon information to two-dimensional digital representation without the corresponding physical information obtained in previous open surgery. To overcome these drawbacks, real time augmented reality interfaces including the true mechanical behaviour of organs depending on their internal microstructure need to be developed. For the case of tumour resection, we present here a finite element numerical study of the liver mechanical behaviour including the effects of its own vascularisation through numerical indentation tests in order extract the corresponding macroscopic behaviour. The obtained numerical results show excellent correlation of the corresponding force-displacement curves when compared with macroscopic experimental data available in the literature.
authors.affiliation: Laboratoire des Sciences de l'Ingénieur, de l'Informatique et de l'Imagerie (ICube), Université de Strasbourg, CNRS, 67000 Strasbourg, France.
authors.forename: Michaël
authors.initials: M
authors.lastname: Kugler
authors.affiliation: Institut de Recherche contre les Cancers de l'Appareil Digestif (IRCAD), 67000 Strasbourg, France.
authors.forename: Alexandre
authors.initials: A
authors.lastname: Hostettler
authors.affiliation: Institut de Recherche contre les Cancers de l'Appareil Digestif (IRCAD), 67000 Strasbourg, France.
authors.forename: Luc
authors.initials: L
authors.lastname: Soler
authors.affiliation: High Performance Computing Institute (ICI), Ecole Centrale de Nantes, 44300 Nantes, France.
authors.forename: Domenico
authors.initials: D
authors.lastname: Borzacchiello
authors.affiliation: High Performance Computing Institute (ICI), Ecole Centrale de Nantes, 44300 Nantes, France.
authors.forename: Francisco
authors.initials: F
authors.lastname: Chinesta
authors.affiliation: Laboratoire des Sciences de l'Ingénieur, de l'Informatique et de l'Imagerie (ICube), Université de Strasbourg, CNRS, 67000 Strasbourg, France.
authors.forename: Daniel
authors.initials: D
authors.lastname: George
authors.affiliation: Laboratoire des Sciences de l'Ingénieur, de l'Informatique et de l'Imagerie (ICube), Université de Strasbourg, CNRS, 67000 Strasbourg, France.
authors.forename: Yves
authors.initials: Y
authors.lastname: Rémond
mesh_terms: D001696:Biomechanical Phenomena; D003198:Computer Simulation; D020342:Finite Element Analysis; D006801:Humans; D021621:Imaging, Three-Dimensional / Q000379:methods*; D008099:Liver / Q000033:anatomy & histology / Q000098:blood supply* / Q000601:surgery*; D019060:Minimally Invasive Surgical Procedures / Q000379:methods*; D008953:Models, Anatomic
keywords: Liver; finite element model; indentation tests; numerical simulation; real time; vascularisation