title: Endoscopic nipple sparing mastectomy with immediate implant-based reconstruction versus breast conserving surgery: a long-term study.
abstract: To evaluate the differences between endoscopic nipple sparing mastectomy (ENSM) with immediate implant-based reconstruction and breast conserving surgery(BCS) applied to early-stage breast cancer in postoperative outcomes, function, and cosmesis. we made a prospective, non-randomized study reviewed a total of 346 cases of breast cancer from January 2007 to December 2011, including 189 cases of BCS and 157 cases of ENSM. All the patients were followed up to April 2016, with a median follow-up time of 74 months. The operative time, blood loss and drainage, postoperative complications, postoperative cosmesis, local recurrence rate, disease-free survival rate and overall survival rate of the two groups were compared. we found out that the operative time of ENSM was longer than that of BCS. There was no difference in blood loss and drainage, the postoperative complications, the disease-free survival rate and overall survival rate between the two groups. In regarding to cosmesis, patients in the ENSM group were more likely to get a satisfactory postoperative breast appearance. we reached a conclusion that ENSM is a safe and effective operative method retainingadvantages of TSSM to further improve the postoperative cosmetic effect, without increasing other risks. The surgery provides a new choice for patients with early-stage breast cancer.
authors.affiliation: Breast surgery, Southwest Hospital, the Third Military Medical University, Chongqing 400038, China.
authors.forename: Junze
authors.initials: J
authors.lastname: Du
authors.affiliation: Head-neck surgery, Tumor Hospital, Guangxi Medical University, Guangxi, 530021, China.
authors.forename: Quankun
authors.initials: Q
authors.lastname: Liang
authors.affiliation: Breast surgery, Southwest Hospital, the Third Military Medical University, Chongqing 400038, China.
authors.forename: Xiaowei
authors.initials: X
authors.lastname: Qi
authors.affiliation: Three glands surgery, the Second Affiliated Hospital, Chongqing Medical University, Chongqing 400010, China.
authors.forename: Jia
authors.initials: J
authors.lastname: Ming
authors.affiliation: Breast surgery, Southwest Hospital, the Third Military Medical University, Chongqing 400038, China.
authors.forename: Jing
authors.initials: J
authors.lastname: Liu
authors.affiliation: Breast surgery, Southwest Hospital, the Third Military Medical University, Chongqing 400038, China.
authors.forename: Ling
authors.initials: L
authors.lastname: Zhong
authors.affiliation: Breast surgery, Southwest Hospital, the Third Military Medical University, Chongqing 400038, China.
authors.forename: Linjun
authors.initials: L
authors.lastname: Fan
authors.affiliation: Breast surgery, Southwest Hospital, the Third Military Medical University, Chongqing 400038, China.
authors.forename: Jun
authors.initials: J
authors.lastname: Jiang
mesh_terms: D000328:Adult; D019928:Breast Implantation / Q000379:methods*; D001943:Breast Neoplasms / Q000601:surgery*; D018572:Disease-Free Survival; D004724:Endoscopy; D005260:Female; D006801:Humans; D008408:Mastectomy / Q000379:methods*; D009558:Nipples / Q000601:surgery*; D011183:Postoperative Complications; D011446:Prospective Studies; D019651:Plastic Surgery Procedures / Q000379:methods*; D016896:Treatment Outcome