title: Two new unsaturated fatty acids from the whole plant of Pothos chinensis.
abstract: Two new unsaturated fatty acids, (Z)-octadec-13-en-11-ynoic acid (1) and (Z)-octadec-16-en-12,14-diynoic acid (2), along with six known compounds were isolated from the whole plant of Pothos chinensis. The structures of these compounds were elucidated by detailed spectroscopic analysis, including 1D and 2D NMR data. Compound 2 showed moderate antibacterial activity against Staphylococcus aureus.
authors.affiliation: a Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education , Institute of Medicinal Plant Development, Peking Union Medical College and Chinese Academy of Medical Sciences , Beijing 100193 , China.|b School of Pharmacy , Henan University of Traditional Chinese Medicine , Zhengzhou 450008 , China.
authors.forename: Jin-Guang
authors.initials: JG
authors.lastname: Si
authors.affiliation: c Jiangsu HaiCi Biological Pharmaceutical Co., Ltd. , Taizhou 225400 , China.
authors.forename: Hao-Li
authors.initials: HL
authors.lastname: Sun
authors.affiliation: b School of Pharmacy , Henan University of Traditional Chinese Medicine , Zhengzhou 450008 , China.
authors.forename: Tao
authors.initials: T
authors.lastname: Zhang
authors.affiliation: b School of Pharmacy , Henan University of Traditional Chinese Medicine , Zhengzhou 450008 , China.
authors.forename: Qiu-Bo
authors.initials: QB
authors.lastname: Zhang
authors.affiliation: b School of Pharmacy , Henan University of Traditional Chinese Medicine , Zhengzhou 450008 , China.
authors.forename: Meng-Hua
authors.initials: MH
authors.lastname: Wang
authors.affiliation: b School of Pharmacy , Henan University of Traditional Chinese Medicine , Zhengzhou 450008 , China.|d School of Traditional Chinese Medicine , Shenyang Pharmaceutical University , Shenyang 110016 , China.
authors.forename: Jia-Huan
authors.initials: JH
authors.lastname: Chen
authors.affiliation: b School of Pharmacy , Henan University of Traditional Chinese Medicine , Zhengzhou 450008 , China.
authors.forename: Ling-Yu
authors.initials: LY
authors.lastname: Li
authors.affiliation: b School of Pharmacy , Henan University of Traditional Chinese Medicine , Zhengzhou 450008 , China.
authors.forename: Zhong-Mei
authors.initials: ZM
authors.lastname: Zou
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D005231:Fatty Acids, Unsaturated / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D056945:Hep G2 Cells; D006801:Humans; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D013211:Staphylococcus aureus / Q000187:drug effects; D013237:Stereoisomerism
chemical_list: C000625174:(Z)-octadec-13-en-11-ynoic acid; C000625175:(Z)-octadec-16-en-12,14-diynoic acid; D000900:Anti-Bacterial Agents; D004365:Drugs, Chinese Herbal; D005231:Fatty Acids, Unsaturated
keywords: NMR; Pothos chinensis; antibacterial activity; unsaturated fatty acids