title: Multiple intradural-extramedullary spinal ependymomas including tumors with different histological features.
abstract: We report a rare case with multiple intradural-extramedullary spinal ependymomas with different histological features.
  
  
  
  A 26-year-old female presented to our hospital because of difficulty in walking due to progressive paresis. Magnetic resonance imaging of the thoracic spinal cord showed multiple spinal cord tumors. Surgical resection of these tumors was performed and a different histological diagnosis including World Health Organization Grade III anaplastic ependymoma and Grade II ependymoma was obtained using the resected specimen. Additional radiotherapy and chemotherapy were also performed, and a successful outcome has been maintained for at least 3 years after surgery.
  
  
  
  Surgical resections and subsequent radiotherapy and chemotherapy for cases with multiple intradural-extramedullary ependymomas can result in a good postoperative course.
authors.affiliation: Department of Orthopaedic Surgery, Gunma University Graduate School of Medicine, 3-39-22, Showa, Maebashi, Gunma, 371-8511, Japan.
authors.forename: Akira
authors.initials: A
authors.lastname: Honda
authors.affiliation: Department of Orthopaedic Surgery, Gunma University Graduate School of Medicine, 3-39-22, Showa, Maebashi, Gunma, 371-8511, Japan. yoiizuka@gunma-u.ac.jp.
authors.forename: Yoichi
authors.initials: Y
authors.lastname: Iizuka
authors.affiliation: Department of Pathology, Gunma University Hospital, 3-39-22, Showa, Maebashi, Gunma, 371-8511, Japan.
authors.forename: Junko
authors.initials: J
authors.lastname: Hirato
authors.affiliation: Department of Radiation Oncology, Gunma University Graduate School of Medicine, 3-39-22, Showa, Maebashi, Gunma, 371-8511, Japan.
authors.forename: Hiroki
authors.initials: H
authors.lastname: Kiyohara
authors.affiliation: Department of Orthopaedic Surgery, Gunma University Graduate School of Medicine, 3-39-22, Showa, Maebashi, Gunma, 371-8511, Japan.
authors.forename: Haku
authors.initials: H
authors.lastname: Iizuka
mesh_terms: D000328:Adult; D003131:Combined Modality Therapy; D004806:Ependymoma / Q000000981:diagnostic imaging / Q000473:pathology* / Q000628:therapy; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D009378:Neoplasms, Multiple Primary / Q000000981:diagnostic imaging / Q000473:pathology* / Q000628:therapy; D013120:Spinal Cord Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000628:therapy; D013904:Thoracic Vertebrae
keywords: Ependymoma; Mixture of different histology; Multiple spinal cord tumor