title: Systematic Review and Critical Analysis of Cost Studies Associated with Parkinson's Disease.
abstract: Parkinson's disease (PD) is the second most prevalent neurodegenerative disease worldwide, affecting more than four million people. Typically, it affects individuals above 45, when they are still productive, compromising both aging and quality of life. Therefore, the cost of the disease must be identified, so that the use of resources can be rational and efficient. Additionally, in Brazil, there is a lack of research on the costs of neurodegenerative diseases, such as PD, a gap addressed in this study. This systematic review critically addresses the various methodologies used in original research around the world in the last decade on the subject, showing that costs are hardly comparable. Nonetheless, the economic and social impacts are implicit, and important information for public health agents is provided.
authors.affiliation: Programa de Pós-Graduação, Hospital Israelita Albert Einstein, São Paulo, SP, Brazil.
authors.forename: Tânia M
authors.initials: TM
authors.lastname: Bovolenta
authors.affiliation: Movement Disorders Department in Neurology, Universidade Federal de São Paulo (UNIFESP), São Paulo, SP, Brazil.
authors.forename: Sônia Maria Cesar
authors.initials: SM
authors.lastname: de Azevedo Silva
authors.affiliation: Universidade Federal de São Paulo (UNIFESP), São Paulo, SP, Brazil.
authors.forename: Roberta
authors.initials: R
authors.lastname: Arb Saba
authors.affiliation: Universidade Federal de São Paulo (UNIFESP), São Paulo, SP, Brazil.
authors.forename: Vanderci
authors.identifier: 0000-0002-8723-2757
authors.initials: V
authors.lastname: Borges
authors.affiliation: Universidade Federal de São Paulo (UNIFESP), São Paulo, SP, Brazil.
authors.forename: Henrique Ballalai
authors.initials: HB
authors.lastname: Ferraz
authors.affiliation: Neurology Program, Hospital Israelita Albert Einstein, São Paulo, SP, Brazil.
authors.forename: Andre C
authors.identifier: 0000-0003-4590-2983
authors.initials: AC
authors.lastname: Felicio