title: Clinical outcomes of switching from insulin glargine to NPH insulin in indigent patients at a charitable pharmacy: The Charitable Insulin NPH: Care for the Indigent study.
abstract: OBJECTIVE
  To assess the clinical outcomes of indigent patients with type 2 diabetes served by a charitable pharmacy after therapy change from insulin glargine to NPH insulin.
  
  
  METHODS
  This was a 24-week prospective pilot study.
  
  
  METHODS
  Community charitable pharmacy.
  
  
  METHODS
  Underserved, financially disadvantaged adults with type 2 diabetes.
  
  
  METHODS
  Conversion from insulin glargine to NPH insulin.
  
  
  METHODS
  HbA1c, 30-day average blood glucose, number of suspected and confirmed hypoglycemic episodes, total insulin dose, and Morisky Medication Adherence Scale (MMAS) scores.
  
  
  RESULTS
  Patients in both control and intervention groups improved in disease-state clinical markers, safety profile, and total insulin dose. MMAS scores were unchanged.
  
  
  CONCLUSIONS
  There were no statistically significant differences in glycemic control or hypoglycemic episodes between the control (NPH insulin) or intervention group (insulin glargine to NPH insulin).
authors.forename: Russell
authors.initials: R
authors.lastname: Curington
authors.forename: Mike
authors.initials: M
authors.lastname: Espel
authors.forename: Pamela C
authors.initials: PC
authors.lastname: Heaton
authors.forename: Heidi
authors.initials: H
authors.lastname: Luder
authors.forename: Bethanne
authors.initials: B
authors.lastname: Brown
mesh_terms: D001786:Blood Glucose / Q000187:drug effects; D003924:Diabetes Mellitus, Type 2 / Q000188:drug therapy*; D005260:Female; D006442:Glycated Hemoglobin / Q000378:metabolism; D006801:Humans; D007003:Hypoglycemia / Q000139:chemically induced; D007004:Hypoglycemic Agents / Q000627:therapeutic use; D000069036:Insulin Glargine / Q000627:therapeutic use*; D007336:Insulin, Isophane / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D010593:Pharmaceutical Services; D010594:Pharmacies; D010865:Pilot Projects; D011446:Prospective Studies
chemical_list: D001786:Blood Glucose; D006442:Glycated Hemoglobin; D007004:Hypoglycemic Agents; D000069036:Insulin Glargine; D007336:Insulin, Isophane