title: Transforming Concepts Into Clinical Trials and Creating a Multisite Network: The Leadership and Operations Center of the Antibacterial Resistance Leadership Group.
abstract: The Leadership and Operations Center (LOC) is responsible for facilitating, coordinating, and implementing the Antibacterial Resistance Leadership Group (ARLG) scientific agenda by engaging thought leaders; soliciting research proposals; and developing the processes, tools, and infrastructure required to operationalize studies and create and sustain the ARLG network. These efforts are ongoing as new projects are developed and the network expands and grows to address the ever-changing priorities in antibacterial resistance. This article describes the innovations, accomplishments, and opportunities of the LOC since the inception of the ARLG in 2013.
authors.affiliation: Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina.
authors.forename: Heather R
authors.initials: HR
authors.lastname: Cross
authors.affiliation: University of Maryland School of Medicine, Baltimore.
authors.forename: Anthony
authors.initials: A
authors.lastname: Harris
authors.affiliation: Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina.
authors.forename: Rebekka M
authors.initials: RM
authors.lastname: Arias
authors.affiliation: University of California, San Francisco, San Francisco General Hospital; and.
authors.forename: Henry F Chip
authors.initials: HF
authors.lastname: Chambers
authors.affiliation: Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina.|Division of Infectious Diseases, Department of Medicine, Duke University Medical Center, Durham, North Carolina.
authors.forename: Vance G
authors.initials: VG
authors.lastname: Fowler
mesh_terms: D035843:Biomedical Research / Q000458:organization & administration*; D002986:Clinical Trials as Topic / Q000458:organization & administration / Q000592:standards; D003140:Communicable Disease Control / Q000458:organization & administration; D024881:Drug Resistance, Bacterial; D006801:Humans; D007857:Leadership; D016730:Program Development; D012108:Research Personnel; D000078329:Workforce
keywords: antibacterial resistance; clinical trial network; infectious disease; mentoring.