title: Aspergillus fumigatusnative valve infective endocarditis in an otherwise healthy adult.
abstract: BACKGROUND
  Fungal endocarditis is a rare cause of infective endocarditis, andAspergillusspp. account for up to 30 % of all cases. Risk factors include intravenous drug use, immunosuppression, malignancy and the presence of prosthetic valves.
  
  
  METHODS
  We present a case ofA. fumigatusendocarditis in a patient without any known or described risk factors.
  
  
  CONCLUSIONS
  Diagnosis ofAspergillusendocarditis requires a high clinical index of suspicion, given the initial non-specific presentation, and treatment may require both medical and surgical therapies to ensure improved outcomes, but mortality rates still approach 80 %. Voriconazole remains the antifungal agent of choice.
authors.affiliation: Section of Infectious Diseases, Department of Internal Medicine, Yale School of Medicine , New Haven, CT 6520 , USA.
authors.forename: Uchenna
authors.initials: U
authors.lastname: Ikediobi
authors.affiliation: Section of Infectious Diseases, Department of Internal Medicine, Yale School of Medicine , New Haven, CT 6520 , USA.
authors.forename: Richard E
authors.initials: RE
authors.lastname: Sutton
keywords: Aspergillus fumigatus; fungal endocarditis; native valve endocarditis