title: Supraclavicular lymph node metastases from malignant gastrointestinal stromal tumor of the jejunum: A case report with review of the literature.
abstract: Gastrointestinal stromal tumors (GISTs) represent the most common mesenchymal tumors of the alimentary tract. These tumors may have different clinical and biological behaviors. Malignant forms usually spread via a hematogenous route, and lymph node metastases rarely occur. Herein, we report a patient with a jejunal GIST who developed supraclavicular lymph node metastasis. We conclude that lymphatic diffusion via the mediastinal lymphatic station to the supraclavicular lymph nodes can be a potential metastatic route for GISTs.
authors.affiliation: Chi Ma, Jin-Yao Nin, Guo-Chang Wu, Li-Xin Jiang, Hai-Tao Zheng, Department of Gastrointestinal and Thyroid Surgery, Yuhuangding Hospital Affiliated to Qingdao University, Yantai 264000, Shandong Province, China.
authors.forename: Chi
authors.initials: C
authors.lastname: Ma
authors.affiliation: Chi Ma, Jin-Yao Nin, Guo-Chang Wu, Li-Xin Jiang, Hai-Tao Zheng, Department of Gastrointestinal and Thyroid Surgery, Yuhuangding Hospital Affiliated to Qingdao University, Yantai 264000, Shandong Province, China.
authors.forename: Shao-Long
authors.initials: SL
authors.lastname: Hao
authors.affiliation: Chi Ma, Jin-Yao Nin, Guo-Chang Wu, Li-Xin Jiang, Hai-Tao Zheng, Department of Gastrointestinal and Thyroid Surgery, Yuhuangding Hospital Affiliated to Qingdao University, Yantai 264000, Shandong Province, China.
authors.forename: Xin-Cheng
authors.initials: XC
authors.lastname: Liu
authors.affiliation: Chi Ma, Jin-Yao Nin, Guo-Chang Wu, Li-Xin Jiang, Hai-Tao Zheng, Department of Gastrointestinal and Thyroid Surgery, Yuhuangding Hospital Affiliated to Qingdao University, Yantai 264000, Shandong Province, China.
authors.forename: Jin-Yao
authors.initials: JY
authors.lastname: Nin
authors.affiliation: Chi Ma, Jin-Yao Nin, Guo-Chang Wu, Li-Xin Jiang, Hai-Tao Zheng, Department of Gastrointestinal and Thyroid Surgery, Yuhuangding Hospital Affiliated to Qingdao University, Yantai 264000, Shandong Province, China.
authors.forename: Guo-Chang
authors.initials: GC
authors.lastname: Wu
authors.affiliation: Chi Ma, Jin-Yao Nin, Guo-Chang Wu, Li-Xin Jiang, Hai-Tao Zheng, Department of Gastrointestinal and Thyroid Surgery, Yuhuangding Hospital Affiliated to Qingdao University, Yantai 264000, Shandong Province, China.
authors.forename: Li-Xin
authors.initials: LX
authors.lastname: Jiang
authors.affiliation: Chi Ma, Jin-Yao Nin, Guo-Chang Wu, Li-Xin Jiang, Hai-Tao Zheng, Department of Gastrointestinal and Thyroid Surgery, Yuhuangding Hospital Affiliated to Qingdao University, Yantai 264000, Shandong Province, China.
authors.forename: Alessandro
authors.initials: A
authors.lastname: Fancellu
authors.affiliation: Chi Ma, Jin-Yao Nin, Guo-Chang Wu, Li-Xin Jiang, Hai-Tao Zheng, Department of Gastrointestinal and Thyroid Surgery, Yuhuangding Hospital Affiliated to Qingdao University, Yantai 264000, Shandong Province, China.
authors.forename: Alberto
authors.initials: A
authors.lastname: Porcu
authors.affiliation: Chi Ma, Jin-Yao Nin, Guo-Chang Wu, Li-Xin Jiang, Hai-Tao Zheng, Department of Gastrointestinal and Thyroid Surgery, Yuhuangding Hospital Affiliated to Qingdao University, Yantai 264000, Shandong Province, China.
authors.forename: Hai-Tao
authors.initials: HT
authors.lastname: Zheng
mesh_terms: D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000627:therapeutic use; D001707:Biopsy, Needle; D017024:Chemotherapy, Adjuvant; D017707:Erythrocyte Transfusion; D046152:Gastrointestinal Stromal Tumors / Q000150:complications* / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy; D006801:Humans; D000068877:Imatinib Mesylate / Q000008:administration & dosage / Q000627:therapeutic use; D007583:Jejunum / Q000473:pathology / Q000601:surgery; D008198:Lymph Nodes / Q000473:pathology; D008207:Lymphatic Metastasis; D008297:Male; D008551:Melena / Q000209:etiology* / Q000628:therapy; D008875:Middle Aged; D037981:Neck Dissection; D060787:Neoplasm Grading; D000072078:Positron Emission Tomography Computed Tomography; D013274:Stomach Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy; D014463:Ultrasonography
chemical_list: D000970:Antineoplastic Agents; D000068877:Imatinib Mesylate
keywords: Gastrointestinal stromal tumor; Lymph nodes; Metastasis