title: REPLY.
authors.affiliation: Divisions of Hepatology and Critical Care Medicine, University of Alberta, Edmonton, Alberta, Canada.
authors.forename: Constantine J
authors.identifier: 0000-0002-1555-1089
authors.initials: CJ
authors.lastname: Karvellas
authors.affiliation: Department of Public Health Sciences, Medical University of South Carolina, Charleston, SC.
authors.forename: Jaime L
authors.initials: JL
authors.lastname: Speiser
authors.affiliation: Hepato-neuro Laboratory CRCHUM, Université de Montréal, Montréal, Québec, Canada.
authors.forename: Mélanie
authors.identifier: 0000-0001-5395-5853
authors.initials: M
authors.lastname: Tremblay
authors.affiliation: Division of Digestive and Liver Diseases, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX.
authors.forename: William M
authors.initials: WM
authors.lastname: Lee
authors.affiliation: Hepato-neuro Laboratory CRCHUM, Université de Montréal, Montréal, Québec, Canada.
authors.forename: Christopher F
authors.initials: CF
authors.lastname: Rose