title: Associations between depressive syndromes and HIV risk behaviors among San Francisco men who have sex with men.
abstract: HIV prevention plans for men who have sex with men (MSM) are often multifaceted. They involve reduction of sexual risk behaviors, such as condomless intercourse, but also often include pharmaceutical approaches, such as early treatment of HIV-infected individuals with antiretroviral therapy (ART). Effectiveness is possibly threatened by individual-level factors, such as depression. In this study of 322 San Francisco MSM (240 HIV-uninfected individuals and 82 HIV-infected individuals, according to self-report), we examine associations between depressive syndromes and HIV risk behaviors (sexual risk behaviors and ART non-adherence). Our study failed to find evidence that depressive syndromes lead to increases in ART non-adherence (risk difference, RD: 27.9; 95% confidence interval, CI: -3.5, 59.3). However, the study does suggest an association between depressive syndromes and concurrence of non-adherence and potentially HIV-discordant condomless receptive anal intercourse (RD: 36.0; 95% CI: 5.2, 66.8). Among HIV-uninfected MSM, our study suggests negative associations between depressive syndromes and sexual risk behaviors. We recommend screening and treatment of depression among HIV-infected MSM.
authors.affiliation: a Department of Public Health , Center for Public Health Research , San Francisco , USA.
authors.forename: Yea-Hung
authors.initials: YH
authors.lastname: Chen
authors.affiliation: a Department of Public Health , Center for Public Health Research , San Francisco , USA.|b Department of Epidemiology and Biostatistics , University of California , San Francisco , USA.
authors.forename: Henry Fisher
authors.initials: HF
authors.lastname: Raymond
mesh_terms: D000328:Adult; D017280:Condoms; D003866:Depressive Disorder / Q000453:epidemiology* / Q000523:psychology; D015658:HIV Infections / Q000188:drug therapy / Q000453:epidemiology / Q000523:psychology*; D018451:Homosexuality, Male / Q000523:psychology*; D006801:Humans; D008297:Male; D055118:Medication Adherence; D008875:Middle Aged; D015995:Prevalence; D012309:Risk-Taking; D012495:San Francisco / Q000453:epidemiology; D012725:Sexual Behavior; D047568:Unsafe Sex / Q000706:statistics & numerical data*; D055815:Young Adult
keywords: Depression; HIV; antiretroviral therapy (ART); condomless intercourse; men who have sex with men (MSM)