title: Teaching an Old Dog New Tricks: Colchicine in Cardiovascular Medicine.
abstract: Colchicine is one of the oldest known drugs that remains part of the current pharmacopeia. Recent studies have examined the efficacy of colchicine in cardiology with promising results. We conducted a search of electronic databases for studies on colchicine in cardiovascular medicine published through October 2016. As the utilization of colchicine in the management of cardiac conditions grows, it is paramount that internists and cardiologists are familiarized with its benefits and risks. We present a comprehensive review of the role of colchicine in the management of cardiovascular diseases with a strong emphasis on side effects and potential drug interactions.
authors.affiliation: Internal Medicine Department, Cleveland Clinic, Cleveland, OH, 33195, USA.
authors.forename: Kevin
authors.initials: K
authors.lastname: Chen
authors.affiliation: Cardiovascular Medicine Department, Cleveland Clinic, Cleveland, OH, 33195, USA. schenoa@ccf.org.
authors.forename: Aldo L
authors.initials: AL
authors.lastname: Schenone
authors.affiliation: Cardiovascular Medicine Department, Cleveland Clinic, Cleveland, OH, 33195, USA.
authors.forename: Nyal
authors.initials: N
authors.lastname: Borges
authors.affiliation: Pharmacy Department, Cleveland Clinic, Cleveland, OH, 33195, USA.
authors.forename: Michael
authors.initials: M
authors.lastname: Militello
authors.affiliation: Cardiovascular Medicine Department, Cleveland Clinic, Cleveland, OH, 33195, USA.
authors.forename: Venu
authors.initials: V
authors.lastname: Menon
mesh_terms: D002309:Cardiology / Q000379:methods; D002317:Cardiovascular Agents / Q000627:therapeutic use*; D002318:Cardiovascular Diseases / Q000188:drug therapy*; D003078:Colchicine / Q000627:therapeutic use*; D004347:Drug Interactions; D006801:Humans
chemical_list: D002317:Cardiovascular Agents; D003078:Colchicine
keywords: Acute Coronary Syndrome; Atrial Fibrillation; Colchicine; Familial Mediterranean Fever; Stable Coronary Artery Disease