title: Burn-related peripheral neuropathy: A systematic review.
abstract: Peripheral neuropathy is the most frequent disabling neuromuscular complication of burns. However, the insidious and progressive onset of burn neuropathy makes it often undiagnosed or overlooked. In our study, we reviewed the current studies on the burn-related peripheral neuropathy to summarize the morbidity, mechanism, detecting method and management of peripheral neuropathy in burn patients. Of the 1533 burn patients included in our study, 98 cases (6.39%) were presented with peripheral neuropathy. Thermal and electrical burns were the most common etiologies. Surgical procedures, especially nerve decompression, showed good effect on functional recovery of both acute and delayed peripheral neuropathy in burn patients. It is noteworthy that, for early detection and prevention of peripheral neuropathy, electrodiagnostic examinations should be performed on burn patients independent of symptoms. Still, the underlying mechanisms of burn-related peripheral neuropathy remain to be clarified.
authors.affiliation: Department of Orthopedic Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
authors.forename: Yiji
authors.initials: Y
authors.lastname: Tu
authors.affiliation: Joseph M. Still Burn and Reconstruction Center, Jackson, MS, USA.
authors.forename: William C
authors.initials: WC
authors.lastname: Lineaweaver
authors.affiliation: Department of Orthopedic Surgery, Sixth People's Hospital, Shanghai, China.
authors.forename: Xianyou
authors.initials: X
authors.lastname: Zheng
authors.affiliation: Department of Orthopedic Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
authors.forename: Zenggan
authors.initials: Z
authors.lastname: Chen
authors.affiliation: Joseph M. Still Burn and Reconstruction Center, Augusta, GA, USA.
authors.forename: Fred
authors.initials: F
authors.lastname: Mullins
authors.affiliation: Joseph M. Still Burn and Reconstruction Center, Jackson, MS, USA. Electronic address: feng.zhang@jmsburncenters.com.
authors.forename: Feng
authors.initials: F
authors.lastname: Zhang
mesh_terms: D000200:Action Potentials; D002056:Burns / Q000150:complications*; D020918:Complex Regional Pain Syndromes / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology / Q000628:therapy; D000072700:Conservative Treatment; D019299:Decompression, Surgical / Q000379:methods; D004576:Electromyography; D006801:Humans; D009408:Nerve Compression Syndromes / Q000209:etiology* / Q000503:physiopathology / Q000601:surgery; D009431:Neural Conduction; D010523:Peripheral Nervous System Diseases / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology / Q000628:therapy
keywords: Burn; Mechanism; Nerve decompression; Peripheral neuropathy