title: Influences of surface treatments with abrasive paper and sand-blasting on surface morphology, hydrophilicity, mineralization and osteoblasts behaviors of n-CS/PK composite.
abstract: The surfaces of nano-calcium silicate (n-CS)/polyetheretherketone (PK) composites were treated with abrasive paper and sand-blasting, and the surfaces performances of the as-treated composites were studied. The results showed that the surface roughness, hydrophilicity and mineralization of the simulated body fluid (SBF) of the composites surfaces were significantly improved, and the properties of the composites treated by with sand-blasting were better than those treated with abrasive paper. Moreover, the treated composites significantly promoted osteoblasts responses, such as cell attachment, spreading, proliferation and alkaline phosphatase (ALP) activity, compared to un-treated composites, and the cellular responses to the composites treated with sand-blasting were better than those treated with abrasive paper. The results suggested that surface treatment with sand-blasting was an effective method to greatly improve the surface bioperformances of the n-CS/PK composite, and this treated composite with improved bioactivity and cytocompatibility might be a promising implant material for orthopedic applications.
authors.affiliation: Department of Orthopedics, Huai'an First People's Hospital, Nanjing medical university, Huai'an, 223001, Jiangsu Province, PR China.
authors.forename: Xiaoming
authors.initials: X
authors.lastname: Tang
authors.affiliation: Department of orthopedics, Shanghai Zhabei Central Hospital, Shanghai, 200070, PR China.
authors.forename: Kai
authors.initials: K
authors.lastname: Huang
authors.affiliation: Department of Orthopedics, Huai'an First People's Hospital, Nanjing medical university, Huai'an, 223001, Jiangsu Province, PR China.
authors.forename: Jian
authors.initials: J
authors.lastname: Dai
authors.affiliation: Key Laboratory for Ultrafine Materials of Ministry of Education, East China University of Science and Technology, Shanghai, 200237, PR China.
authors.forename: Zhaoying
authors.initials: Z
authors.lastname: Wu
authors.affiliation: Key Laboratory for Ultrafine Materials of Ministry of Education, East China University of Science and Technology, Shanghai, 200237, PR China.
authors.forename: Liang
authors.initials: L
authors.lastname: Cai
authors.affiliation: Department of Orthopedic Surgery, Changzheng Hospital, Second Military Medical University, Shanghai, 20003, PR China.
authors.forename: Lili
authors.initials: L
authors.lastname: Yang
authors.affiliation: Key Laboratory for Ultrafine Materials of Ministry of Education, East China University of Science and Technology, Shanghai, 200237, PR China.
authors.forename: Jie
authors.initials: J
authors.lastname: Wei
authors.affiliation: Department of Orthopedics, Huai'an First People's Hospital, Nanjing medical university, Huai'an, 223001, Jiangsu Province, PR China. sunhailang2016@sina.com.
authors.forename: Hailang
authors.initials: H
authors.lastname: Sun