title: Hippo interferes with antiviral defences.
abstract: The Hippo pathway responds to environmental factors including nutrient availability, cell density and substrate stiffness to regulate organ size. This pathway is now shown to also regulate antiviral defence by modulating the TBK1-mediated control of interferon production.
authors.affiliation: Adjuvant Research Group, School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin 2, D02 R590, Ireland.
authors.forename: Natalia
authors.initials: N
authors.lastname: Muñoz-Wolf
authors.affiliation: Adjuvant Research Group, School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin 2, D02 R590, Ireland.|Centre for Research on Adaptive Nanostructures and Nanodevices (CRANN) and the Advanced Materials Bio-Engineering Research Centre (AMBER), Trinity College Dublin, Dublin 2, D02 PN40, Ireland.
authors.forename: Ed C
authors.initials: EC
authors.lastname: Lavelle
mesh_terms: D000998:Antiviral Agents; D009929:Organ Size; D017346:Protein Serine-Threonine Kinases; D015398:Signal Transduction
chemical_list: D000998:Antiviral Agents; D017346:Protein Serine-Threonine Kinases