title: Review of HPV-related diseases and cancers.
abstract: Human papillomavirus (HPV) is a double-stranded circular DNA virus belonging to the papillomavirus family. It is transmitted by skin-to-skin or mucosa-to-mucosa contact and enters the body via cutaneous or mucosal trauma. HPV infection is the most common sexually transmitted disease, although it is usually cured by the immune system. Worldwide, the risk of being infected at least once in a lifetime among both men and women is 50%. HPV infection causes common and anogenital warts, as well as other non-dermatological diseases. The role of HPV in cancer development has been extensively studied, primarily in cervical cancer, but also in other types of neoplasms.
authors.affiliation: Dermatology and Cosmetology Unit - San Raffaele Hospital - Milan - Italy.
authors.forename: Pina
authors.initials: P
authors.lastname: Brianti
authors.affiliation: Dermatology and Cosmetology Unit - San Raffaele Hospital - Milan - Italy.
authors.forename: Eduardo
authors.initials: E
authors.lastname: De Flammineis
authors.affiliation: Dermatology and Cosmetology Unit - San Raffaele Hospital - Milan - Italy.
authors.forename: Santo Raffaele
authors.initials: SR
authors.lastname: Mercuri
mesh_terms: D016679:Genome, Viral; D006801:Humans; D009369:Neoplasms / Q000821:virology*; D027383:Papillomaviridae / Q000235:genetics; D030361:Papillomavirus Infections / Q000473:pathology / Q000517:prevention & control / Q000821:virology*; D053918:Papillomavirus Vaccines / Q000276:immunology; D014412:Tumor Virus Infections / Q000473:pathology / Q000517:prevention & control / Q000821:virology*
chemical_list: D053918:Papillomavirus Vaccines
keywords: Cancer; HPV; skin cancer