title: Rapid assay of resveratrol in red wine by paper spray tandem mass spectrometry and isotope dilution.
abstract: A rapid analytical approach for the assay of resveratrol in red wines, based on Paper Spray Mass Spectrometry (PS-MS) and Multiple Reaction Monitoring (MRM) is described. The assay involves the use of the stable isotope dilution method. The analytical parameters calculated analyzing fortified samples confirm the reliability of the proposed approach, with accuracy values about 100%, and LOD and LOQ values calculated at 0.5 and 0.8μg/mL, respectively. Furthermore, both the recovery, which was quantitative for the analyte, and the reproducibility (RSD%), checked on different days on the same wine, always below 7%, highlighted the consistency of the methodology.
authors.affiliation: Dipartimento di Chimica e Tecnologie Chimiche, Università della Calabria, Via P. Bucci Cubo 12/C, I-87036 Arcavacata di Rende (CS), Italy.
authors.forename: Leonardo
authors.initials: L
authors.lastname: Di Donna
authors.affiliation: Dipartimento di Chimica e Tecnologie Chimiche, Università della Calabria, Via P. Bucci Cubo 12/C, I-87036 Arcavacata di Rende (CS), Italy.
authors.forename: Domenico
authors.initials: D
authors.lastname: Taverna
authors.affiliation: Dipartimento di Scienze e Tecnologie Biologiche Chimiche e Farmaceutiche (STEBICEF), Università degli Studi di Palermo, Via Archirafi 32, Palermo, Italy.
authors.forename: Serena
authors.initials: S
authors.lastname: Indelicato
authors.affiliation: Dipartimento di Chimica e Tecnologie Chimiche, Università della Calabria, Via P. Bucci Cubo 12/C, I-87036 Arcavacata di Rende (CS), Italy.
authors.forename: Anna
authors.initials: A
authors.lastname: Napoli
authors.affiliation: Dipartimento di Chimica e Tecnologie Chimiche, Università della Calabria, Via P. Bucci Cubo 12/C, I-87036 Arcavacata di Rende (CS), Italy.
authors.forename: Giovanni
authors.initials: G
authors.lastname: Sindona
authors.affiliation: Dipartimento di Chimica e Tecnologie Chimiche, Università della Calabria, Via P. Bucci Cubo 12/C, I-87036 Arcavacata di Rende (CS), Italy. Electronic address: fmazzotti@unical.it.
authors.forename: Fabio
authors.initials: F
authors.lastname: Mazzotti
mesh_terms: D007554:Isotopes / Q000032:analysis*; D000077185:Resveratrol; D013267:Stilbenes / Q000008:administration & dosage / Q000627:therapeutic use*; D053719:Tandem Mass Spectrometry / Q000379:methods*; D014920:Wine / Q000032:analysis*
chemical_list: D007554:Isotopes; D013267:Stilbenes; D000077185:Resveratrol
keywords: Ambient mass spectrometry; Isotope dilution; Paper spray; Quantitative assay; Resveratrol