title: Immune Mechanisms and Novel Targets in Rheumatoid Arthritis.
abstract: Significant progress has been made in understanding the pathophysiology of rheumatoid arthritis. It is widely recognized that early institution of treatment is one of the best predictive factors for response to therapy. Several novel approaches are currently being investigated and several novel biologics are in various stages of development. With advances in the fields of proteomics, genomics, and metabolomics, specific phenotypes of the disease can be better identified and specific therapies for particular phases of the disease and specific patients will allow for improved control of this condition.
authors.affiliation: Division of Rheumatology- Cedars Sinai Medical Center, 8750 Wilshire Blvd, Suite 350, Beverly Hills, CA 90211, USA. Electronic address: swamy.venuturupalli@cshs.org.
authors.forename: Swamy
authors.initials: S
authors.lastname: Venuturupalli
mesh_terms: D000818:Animals; D000911:Antibodies, Monoclonal / Q000627:therapeutic use; D001172:Arthritis, Rheumatoid / Q000209:etiology* / Q000378:metabolism / Q000628:therapy*; D001688:Biological Products / Q000627:therapeutic use; D016207:Cytokines / Q000627:therapeutic use; D006801:Humans; D007155:Immunologic Factors / Q000627:therapeutic use; D047428:Protein Kinase Inhibitors / Q000627:therapeutic use; D016896:Treatment Outcome
chemical_list: D000911:Antibodies, Monoclonal; D001688:Biological Products; D016207:Cytokines; D007155:Immunologic Factors; D047428:Protein Kinase Inhibitors
keywords: Biologics; Novel targets; Pathophysiology; Rheumatoid arthritis