title: Analysis of magnetic resonance imaging findings of children with neurologic complications after liver transplantation.
abstract: OBJECTIVE
  To analyze the magnetic resonance imaging findings in children diagnosed with neurologic complications after liver transplantation (LT).
  
  
  METHODS
  A total of 39 patients diagnosed with neurologic complications following LT between 2010 and 2016. Neuroradiologic imaging was performed using cranial magnetic resonance imaging (MRI). Descriptive statistics regarding age, gender, type of complication, diagnostic and therapeutic modalities were calculated and presented as number and percentage.
  
  
  RESULTS
  Our series consisted of 18 girls and 21 boys. Cryptogenic hepatitis (n = 13, 32%), metabolic diseases (Wilson's disease, tyrosinemia and glycogen storage disease) (n = 7, 18%) and fulminant toxic hepatitis (n = 4, 11%) constitute the most frequent indications for LT. The indications for neuroradiological imaging were convulsion and alteration of mental status.
  
  
  CONCLUSIONS
  These central nervous system complications may present in a variable spectrum and convulsions and altered mental state were the most frequent clinical pictures. Imaging studies were normal in approximately one-third of cases; the most frequent pathologic findings were diffuse cerebral edema, atrophy, and PRES. Clinical history, careful examination and integrated analysis of radiologic data as well as close collaboration and multidisciplinary approach are of utmost importance for establishing the diagnosis rapidly and accurately.
authors.affiliation: Department of Pediatric Radiology, Diyarbakır Children's Hospital, 21100, Diyarbakir, Turkey. drmehmet2121@gmail.com.
authors.forename: Mehmet
authors.initials: M
authors.lastname: Öztürk
authors.affiliation: Department of Pediatric Radiology, Inonu University School of Medicine, 44100, Malatya, Turkey.
authors.forename: İsmail
authors.initials: İ
authors.lastname: Akdulum
authors.affiliation: Department of Pediatric Radiology, Inonu University School of Medicine, 44100, Malatya, Turkey.
authors.forename: Nurullah
authors.initials: N
authors.lastname: Dağ
authors.affiliation: Department of Pediatric Radiology, Inonu University School of Medicine, 44100, Malatya, Turkey.
authors.forename: Ahmet
authors.initials: A
authors.lastname: Sığırcı
authors.affiliation: Department of Pediatric Neurology, Inonu University School of Medicine, 44100, Malatya, Turkey.
authors.forename: Serdal
authors.initials: S
authors.lastname: Güngör
authors.affiliation: Department of General Surgery, Inonu University School of Medicine, 44100, Malatya, Turkey.
authors.forename: Sezai
authors.initials: S
authors.lastname: Yılmaz
mesh_terms: D000293:Adolescent; D002493:Central Nervous System Diseases / Q000000981:diagnostic imaging*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D016031:Liver Transplantation; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D011183:Postoperative Complications / Q000000981:diagnostic imaging*; D012189:Retrospective Studies
keywords: Children; Complication; Liver; Magnetic resonance imaging; Neurologic; Transplantation