title: Flourodeoxyglucose positron emission tomography scan may be helpful in the case of ductal variant prostate cancer when prostate specific membrane antigen ligand positron emission tomography scan is negative.
abstract: Gallium-68 prostate specific membrane antigen ligand (Ga-68 PSMA) positron emission tomography/computed tomography (PET/CT) scanning is emerging as a useful imaging modality for the staging of suspected and known recurrent or metastatic prostate cancer and in staging of newly diagnosed higher grade prostate cancer. However, we have observed at our institution that in some cases of the more aggressive ductal variant, Ga-68 PSMA uptake has sometimes been poor compared with prominent 18-flourodeoxyglucose (F-18 FDG) avidity seen in F-18 FDG PET/CT, which would suggest that FDG PET/CT scans are important in staging of ductal pattern prostate cancer.
authors.affiliation: Wesley Medical Imaging, The Wesley Hospital, Brisbane, Queensland, Australia.
authors.forename: Louise M
authors.identifier: http://orcid.org/0000-0002-4681-1891
authors.initials: LM
authors.lastname: McEwan
authors.affiliation: Wesley Medical Imaging, The Wesley Hospital, Brisbane, Queensland, Australia.
authors.forename: David
authors.initials: D
authors.lastname: Wong
authors.affiliation: Wesley Urology Clinic, The Wesley Hospital, Brisbane, Queensland, Australia.
authors.forename: John
authors.initials: J
authors.lastname: Yaxley
mesh_terms: D000368:Aged; D014408:Biomarkers, Tumor / Q000097:blood; D019788:Fluorodeoxyglucose F18; D005710:Gallium Radioisotopes; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000000981:diagnostic imaging / Q000473:pathology; D000072078:Positron Emission Tomography Computed Tomography; D017430:Prostate-Specific Antigen / Q000097:blood; D011471:Prostatic Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology*; D019275:Radiopharmaceuticals
chemical_list: D014408:Biomarkers, Tumor; D005710:Gallium Radioisotopes; D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18; D017430:Prostate-Specific Antigen
keywords: 
  FDG PET
  ; 
  PSMA PET
  ; ductal variant; prostate carcinoma; staging