title: Sphingosine kinase 1 participates in the activation, proliferation and survival of chronic lymphocytic leukemia cells.
authors.affiliation: Laboratorio de Inmunología Oncológica, Instituto de Medicina Experimental (IMEX)-CONICET-Academia Nacional de Medicina (ANM), Buenos Aires, Argentina.|Departamento de Fisiología, Biología Molecular y Celular, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Argentina.
authors.forename: María Belén
authors.initials: MB
authors.lastname: Almejún
authors.affiliation: Laboratorio de Inmunología Oncológica, Instituto de Medicina Experimental (IMEX)-CONICET-Academia Nacional de Medicina (ANM), Buenos Aires, Argentina.|Departamento de Microbiología, Parasitología e Inmunología, Facultad de Medicina, Universidad de Buenos Aires, Argentina.
authors.forename: Mercedes
authors.initials: M
authors.lastname: Borge
authors.affiliation: Laboratorio de Inmunología Oncológica, Instituto de Medicina Experimental (IMEX)-CONICET-Academia Nacional de Medicina (ANM), Buenos Aires, Argentina.
authors.forename: Ana
authors.initials: A
authors.lastname: Colado
authors.affiliation: Laboratorio de Inmunología Oncológica, Instituto de Medicina Experimental (IMEX)-CONICET-Academia Nacional de Medicina (ANM), Buenos Aires, Argentina.
authors.forename: Esteban Enrique
authors.initials: EE
authors.lastname: Elías
authors.affiliation: Laboratorio de Inmunología Oncológica, Instituto de Medicina Experimental (IMEX)-CONICET-Academia Nacional de Medicina (ANM), Buenos Aires, Argentina.
authors.forename: Enrique
authors.initials: E
authors.lastname: Podaza
authors.affiliation: Laboratorio de Inmunología Oncológica, Instituto de Medicina Experimental (IMEX)-CONICET-Academia Nacional de Medicina (ANM), Buenos Aires, Argentina.
authors.forename: Denise
authors.initials: D
authors.lastname: Risnik
authors.affiliation: Laboratorio de Genética Molecular de la Hemofilia, IMEX-CONICET-ANM, Buenos Aires, Argentina.
authors.forename: Carlos Daniel
authors.initials: CD
authors.lastname: De Brasi
authors.affiliation: División Patología Molecular, Instituto de Investigaciones Hematológicas "Mariano R. Castex", Academia Nacional de Medicina, Buenos Aires, Argentina.
authors.forename: Carmen
authors.initials: C
authors.lastname: Stanganelli
authors.affiliation: Laboratorio de Genética de Neoplasias Linfoides, IMEX-CONICET-ANM, Buenos Aires, Argentina.
authors.forename: Irma
authors.initials: I
authors.lastname: Slavutsky
authors.affiliation: Sanatorio Municipal Dr. Julio Méndez, Buenos Aires, Argentina.
authors.forename: María
authors.initials: M
authors.lastname: Cabrejo
authors.affiliation: Sanatorio Municipal Dr. Julio Méndez, Buenos Aires, Argentina.
authors.forename: Horacio
authors.initials: H
authors.lastname: Fernández-Grecco
authors.affiliation: Hospital General de Agudos Dr. Teodoro Álvarez, Buenos Aires, Argentina.
authors.forename: Raimundo Fernando
authors.initials: RF
authors.lastname: Bezares
authors.affiliation: Instituto Alexander Fleming, Buenos Aires, Argentina.
authors.forename: Santiago
authors.initials: S
authors.lastname: Cranco
authors.affiliation: Instituto Alexander Fleming, Buenos Aires, Argentina.
authors.forename: Rubén Ángel
authors.initials: RÁ
authors.lastname: Burgos
authors.affiliation: Instituto Alexander Fleming, Buenos Aires, Argentina.
authors.forename: Julio César
authors.initials: JC
authors.lastname: Sánchez-Ávalos
authors.affiliation: Research Laboratory on Chronic Lymphocytic Leukemia, Institut Pasteur de Montevideo, Montevideo, Uruguay.
authors.forename: Pablo
authors.initials: P
authors.lastname: Oppezzo
authors.affiliation: Laboratorio de Inmunología Oncológica, Instituto de Medicina Experimental (IMEX)-CONICET-Academia Nacional de Medicina (ANM), Buenos Aires, Argentina.|Departamento de Microbiología, Parasitología e Inmunología, Facultad de Medicina, Universidad de Buenos Aires, Argentina.
authors.forename: Mirta
authors.initials: M
authors.lastname: Giordano
authors.affiliation: Laboratorio de Inmunología Oncológica, Instituto de Medicina Experimental (IMEX)-CONICET-Academia Nacional de Medicina (ANM), Buenos Aires, Argentina rominagamberale@gmail.com.|Departamento de Microbiología, Parasitología e Inmunología, Facultad de Medicina, Universidad de Buenos Aires, Argentina.
authors.forename: Romina
authors.initials: R
authors.lastname: Gamberale
mesh_terms: D015415:Biomarkers; D049109:Cell Proliferation / Q000235:genetics; D002470:Cell Survival / Q000235:genetics; D018450:Disease Progression; D005260:Female; D006801:Humans; D016130:Immunophenotyping; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000235:genetics* / Q000378:metabolism / Q000473:pathology; D008297:Male; D017853:Phosphotransferases (Alcohol Group Acceptor) / Q000235:genetics* / Q000378:metabolism; D015398:Signal Transduction; D000099157:Sphingosine Kinase
chemical_list: D015415:Biomarkers; D017853:Phosphotransferases (Alcohol Group Acceptor); D000099157:Sphingosine Kinase