title: Chronic breathlessness associated with poorer physical and mental health-related quality of life (SF-12) across all adult age groups.
abstract: Little is known about the impact of chronic breathlessness (modified Medical Research Council (mMRC) score ≥2 for most days, at least three of the last six months) on health-related quality of life (Short Form-12 (SF-12)). 3005 adults from randomly selected households were interviewed face-to-face in South Australia. mMRC ≥2 community prevalence was 2.9%. Adjusted analyses showed clinically meaningful and statistically significant decrements of physical and mental components of SF-12 (mean SF-12 summary scores in physical (-13.0 (-16.0 to -10.2)) and mental (-10.7 (-13.7 to -7.8)) components compared with people with mMRC=0) as chronic breathlessness severity increased, across five age groupings.
authors.affiliation: Discipline, Palliative and Supportive Services, Flinders University, Adelaide, Australia.|Southern Adelaide Palliative Services, Adelaide, South Australia, Australia.|Hull York Medical School, University of Hull, Hull, UK.
authors.forename: D C
authors.initials: DC
authors.lastname: Currow
authors.affiliation: Population Research and Outcomes Studies Unit, Discipline of Medicine, Health Services Faculty, Adelaide University, Adelaide, Australia.
authors.forename: E
authors.initials: E
authors.lastname: Dal Grande
authors.affiliation: Discipline, Palliative and Supportive Services, Flinders University, Adelaide, Australia.
authors.forename: D
authors.initials: D
authors.lastname: Ferreira
authors.affiliation: Hull York Medical School, University of Hull, Hull, UK.
authors.forename: M J
authors.initials: MJ
authors.lastname: Johnson
authors.affiliation: Discipline, Palliative and Supportive Services, Flinders University, Adelaide, Australia.
authors.forename: N
authors.initials: N
authors.lastname: McCaffrey
authors.affiliation: Department of Respiratory Medicine and Allergology, Lund University, Lund, Sweden.
authors.forename: M
authors.initials: M
authors.lastname: Ekström
mesh_terms: D000328:Adult; D000368:Aged; D002908:Chronic Disease; D004417:Dyspnea / Q000534:rehabilitation*; D005260:Female; D006304:Health Status; D006801:Humans; D008297:Male; D008603:Mental Health; D008875:Middle Aged; D011594:Psychometrics; D011788:Quality of Life; D012720:Severity of Illness Index