title: [Research progress in vasculogenic mimicry in  multiple tumors].
abstract: Vasculogenic mimicry (VM) is a brand-new tumor vascular pattern with the ability to form vessel-like networks without participation of endothelial cells and independent on angiogenesis. It can provide adequate blood supply for tumor growth. The formation of VM involves multiple molecule mechanisms and signal pathways, including cancer stem cell and epithelial-mesenchymal transition. As a unique blood-supply pattern, VM is associated with cancer invasion, metastasis and poor prognosis. Because of its important role in cancer progression, VM will become a new target for therapy of cancers.
authors.affiliation: Genetic Eugenics Division, Maternal and Child Health Hospital of Changde City, Changde Hunan 415000; Cancer Research Institute, Central South University, Changsha 410078, China.
authors.forename: Ju
authors.initials: J
authors.lastname: Bai
authors.affiliation: Department of Pathology, Xiangya Hospital, Central South University, Changsha 410008, China.
authors.forename: Zhijie
authors.initials: Z
authors.lastname: Xu
authors.affiliation: Cancer Research Institute, Central South University, Changsha 410078, China.
authors.forename: Chaoliang
authors.initials: C
authors.lastname: Liao
authors.affiliation: Cancer Research Institute, Central South University, Changsha 410078, China.
authors.forename: Lifang
authors.initials: L
authors.lastname: Yang
mesh_terms: D000067558:Biological Mimicry; D002454:Cell Differentiation; D058750:Epithelial-Mesenchymal Transition; D006801:Humans; D009361:Neoplasm Invasiveness; D009362:Neoplasm Metastasis; D009369:Neoplasms / Q000098:blood supply* / Q000473:pathology; D014411:Neoplastic Stem Cells; D009389:Neovascularization, Pathologic / Q000209:etiology* / Q000503:physiopathology; D058028:Research Report