title: Hot Topics in Primary Care: Medication Adherence in Type 2 Diabetes Mellitus: Real-World Strategies for Addressing a Common Problem.
abstract: The importance of treatment adherence is well established, as poor adherence contributes to disease progression and increased morbidity and mortality. Analysis of 11,272 veterans with T2DM with a mean follow-up of 5 years showed that for each 10% increase in the medication possession ratio, the mean glycated hemoglobin (HbA1c) decreased by 0.24%. Poor adherence also leads to increased health care resource utilization and costs, including more frequent hospitalizations. Conversely, while improved adherence increases medication costs, it can decrease overall health care resource utilization and costs. Improved medication adherence also contributes to improvement in diabetes-related quality of life.
authors.affiliation: Adjunct Clinical Professor, Department of Clinical Pharmacy Practice, Roseman University, Salt Lake City, UT, USA.|Executive Vice President for Education, Primary Care Education Consortium, Los Angeles, CA, USA.
authors.forename: Stephen A
authors.initials: SA
authors.lastname: Brunton
authors.affiliation: President, Behavioral Diabetes Institute, San Diego, CA, USA.|Associate Clinical Professor, University of California, San Diego, CA, USA.
authors.forename: William H
authors.initials: WH
authors.lastname: Polonsky
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D001294:Attitude to Health; D003924:Diabetes Mellitus, Type 2 / Q000188:drug therapy*; D005260:Female; D006442:Glycated Hemoglobin / Q000032:analysis*; D006801:Humans; D007004:Hypoglycemic Agents / Q000627:therapeutic use*; D008297:Male; D055118:Medication Adherence / Q000523:psychology*; D008875:Middle Aged; D010353:Patient Education as Topic; D010361:Patients / Q000523:psychology*; D011320:Primary Health Care / Q000379:methods*; D012189:Retrospective Studies; D012737:Sex Factors; D014481:United States; D016903:Drug Monitoring
chemical_list: D006442:Glycated Hemoglobin; D007004:Hypoglycemic Agents