title: Anti-biofouling function of amorphous nano-Ta2O5coating for VO2-based intelligent windows.
abstract: From environmental and health perspectives, the acquisition of a surface anti-biofouling property holds important significance for the usability of VO2intelligent windows. Herein, we firstly deposited amorphous Ta2O5nanoparticles on VO2film by the magnetron sputtering method. It was found that the amorphous nano-Ta2O5coating possessed a favorable anti-biofouling capability against Pseudomonas aeruginosa as an environmental microorganism model, behind which lay the mechanism that the amorphous nano-Ta2O5could interrupt the microbial membrane electron transport chain and significantly elevate the intracellular reactive oxygen species (ROS) level. A plausible relationship was established between the anti-biofouling activity and physicochemical nature of amorphous Ta2O5nanoparticles from the perspective of defect chemistry. ROS-induced oxidative damage gave rise to microbial viability loss. In addition, the amorphous nano-Ta2O5coating can endow VO2with favorable cytocompatibility with human skin fibroblasts. This study may provide new insights into understanding the anti-biofouling and antimicrobial actions of amorphous transition metal oxide nanoparticles, which is conducive to expanding their potential applications in environmental fields.
authors.affiliation: Department of Orthopaedics and Traumatology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong, People's Republic of China. State Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai 200050, People's Republic of China. Shenzhen Key Laboratory for Innovative Technology in Orthopaedic Trauma, The University of Hong Kong Shenzhen Hospital, Shenzhen 518053, People's Republic of China. University of Chinese Academy of Sciences, Beijing 100049, People's Republic of China.
authors.forename: Jinhua
authors.initials: J
authors.lastname: Li
authors.forename: Geyong
authors.initials: G
authors.lastname: Guo
authors.forename: Jiaxing
authors.initials: J
authors.lastname: Wang
authors.forename: Huaijuan
authors.initials: H
authors.lastname: Zhou
authors.forename: Hao
authors.initials: H
authors.lastname: Shen
authors.forename: Kelvin W K
authors.initials: KW
authors.lastname: Yeung