title: Functional outcomes and complications following B-TURP versus HoLEP for the treatment of benign prostatic hyperplasia: a review of the literature and Meta-analysis.
abstract: OBJECTIVE
  To conduct a systematic review and Meta-analysis of the literature on the efficacy and safety of B-TURP versus HoLEP for the treatment of benign prostatic hyperplasia (BPH) in terms of demographic and clinical baseline characteristics, peri-operative variables, and postoperative outcomes and complications.
  
  
  METHODS
  Trials comparing B-TURP and HoLEP were identified systematically using Pubmed, Embase, CNKI, Web of Science and the Cochrane Library. Primary outcomes were the peak urinary flow rate (Qmax), post-void residual volume (PVR) and international prostate symptom score (IPSS). Secondary outcomes were operation time, irrigation duration, catheterization duration, resected tissue and complications.
  
  
  RESULTS
  Four trials assessing B-TURP and HoLEP were considered eligible for Meta-analysis, including three randomized controlled trials (RCTs) and one retrospective study. There was no statistically significant difference between B-TURP and HoLEP in terms of Qmax, IPSS, PVR at 3-6 months follow-up, operation duration, catheterization duration, resected tissue and complications (p > 0.05). HoLEP was associated with a significantly shorter irrigation time as compared with B-TURP (p < 0.05).
  
  
  CONCLUSIONS
  Both B-TURP and HoLEP are safe and minimally invasive techniques that are similar in terms of symptomatic relief, although these findings need further validation in larger RCTs involving larger numbers of patients and over a longer follow-up duration for B-TURP or HoLEP before a new gold standard procedure emerges for surgical treatment of BPH.
authors.affiliation: a Urology Department, Ruijin Hospital, Shanghai Jiaotong University School of Medicine , Shanghai , P.R. China and.
authors.forename: Xiaoqiang
authors.initials: X
authors.lastname: Qian
authors.affiliation: b Urology Department, Xinhua Hospital, Shanghai Jiaotong University School of Medicine , Shanghai , P.R. China.
authors.forename: Hailong
authors.initials: H
authors.lastname: Liu
authors.affiliation: b Urology Department, Xinhua Hospital, Shanghai Jiaotong University School of Medicine , Shanghai , P.R. China.
authors.forename: Ding
authors.initials: D
authors.lastname: Xu
authors.affiliation: a Urology Department, Ruijin Hospital, Shanghai Jiaotong University School of Medicine , Shanghai , P.R. China and.
authors.forename: Le
authors.initials: L
authors.lastname: Xu
authors.affiliation: a Urology Department, Ruijin Hospital, Shanghai Jiaotong University School of Medicine , Shanghai , P.R. China and.
authors.forename: Fang
authors.initials: F
authors.lastname: Huang
authors.affiliation: a Urology Department, Ruijin Hospital, Shanghai Jiaotong University School of Medicine , Shanghai , P.R. China and.
authors.forename: Wei
authors.initials: W
authors.lastname: He
authors.affiliation: b Urology Department, Xinhua Hospital, Shanghai Jiaotong University School of Medicine , Shanghai , P.R. China.
authors.forename: Jun
authors.initials: J
authors.lastname: Qi
authors.affiliation: a Urology Department, Ruijin Hospital, Shanghai Jiaotong University School of Medicine , Shanghai , P.R. China and.
authors.forename: Yu
authors.initials: Y
authors.lastname: Zhu
authors.affiliation: a Urology Department, Ruijin Hospital, Shanghai Jiaotong University School of Medicine , Shanghai , P.R. China and.
authors.forename: Danfeng
authors.initials: D
authors.lastname: Xu
mesh_terms: D006801:Humans; D053844:Lasers, Solid-State; D008297:Male; D011183:Postoperative Complications / Q000209:etiology; D011184:Postoperative Period; D011468:Prostatectomy / Q000009:adverse effects / Q000379:methods*; D011470:Prostatic Hyperplasia / Q000601:surgery*; D016032:Randomized Controlled Trials as Topic; D012189:Retrospective Studies; D020728:Transurethral Resection of Prostate; D016896:Treatment Outcome
keywords: B-TURP; HoLEP; Meta