title: Thrombosis of A Prosthetic Mitral Valve After Withdrawal of Phenprocoumon Therapy.
abstract: Patients with prosthetic heart valves require lifelong oral anticoagulant therapy based on vitamin K antagonists. These patients may need interruption of their anticoagulant therapy if they have to undergo surgery. The clinical challenge is to identify patients who can safely undergo surgery while continuing their vitamin K antagonist treatment and those who have to take short-acting heparin as part of a bridging therapy. Here we present a case of a patient with a prosthetic mitral valve whose oral anticoagulant therapy was unnecessarily discontinued by the GP prior to an upcoming cataract surgery. As a result, the patient developed thrombosis of the prosthetic mitral valve which needed to be surgically replaced.
authors.affiliation: Kardiologische Praxis Papenburg, Papenburg, Germany.
authors.forename: Andreas
authors.initials: A
authors.lastname: Wilke
authors.affiliation: Abteilung Kardiologie, Marienkrankenhaus Papenburg, Papenburg, Germany.
authors.forename: Christian M
authors.initials: CM
authors.lastname: Wende
authors.affiliation: Abteilung Kardiochirugie, Städtische Kliniken Oldenburg, Oldenburg, Germany.
authors.forename: Michael
authors.initials: M
authors.lastname: Horst
authors.affiliation: Norwich Medical School, University of East Anglia, Norwich, UK.
authors.forename: Dietmar
authors.initials: D
authors.lastname: Steverding
keywords: Bridging therapy; Oral anticoagulant therapy; Prosthetic heart valve thrombosis