title: What do we GANE with age?
abstract: Mather and colleagues provide an impressive cross-level account of how arousal levels modulate behavior, and they support it with data ranging from receptor pharmacology to measures of cognitive function. Here we consider two related questions: (1) Why should the brain engage in different arousal levels? and (2) What are the predicted consequences of age-related changes in norepinephrine signaling for cognitive function?
authors.affiliation: Department of Cognitive,Linguistic, andPsychological Sciences,Brown University,Providence,RI 02912matthew_nassar@brown.edu.
authors.forename: Matthew R
authors.initials: MR
authors.lastname: Nassar
authors.affiliation: Department of Education and Psychology,Freie Universität Berlin,Berlin,Germanyr.bruckner@40fu-berlin.de.
authors.forename: Rasmus
authors.initials: R
authors.lastname: Bruckner
authors.affiliation: Department of Psychology,TU Dresden,Dresden,Germanyben.eppinger@concordia.ca.
authors.forename: Ben
authors.initials: B
authors.lastname: Eppinger
mesh_terms: D000375:Aging / Q000502:physiology*; D001143:Arousal; D001921:Brain / Q000502:physiology*; D003071:Cognition; D006801:Humans; D009638:Norepinephrine
chemical_list: D009638:Norepinephrine