title: IgG4 Aortitis: A Case Report.
abstract: IgG4 aortitis is one of the entities seen in the spectrum of IgG4-related disease (IgG4-RD). It is characterized by serologic (elevated serum IgG4) and histologic features including a lymphoplasmacytic infiltrate with increased numbers of IgG4-positive plasma cells, storiform fibrosis and obliterative phlebitis. Some studies have described a correlation between infections and IgG4 aortitis. We describe a patient with an aneurysm of the infrarenal descending abdominal aorta with features of IgG4-RD, as well as culture evidence of Streptococcus sanguis. [Full article available at http://rimed.org/rimedicaljournal-2017-04.asp].
authors.affiliation: Resident in Pathology, Rhode Island Hospital/ Alpert Medical School of Brown University, Providence, RI.
authors.forename: Shivali
authors.initials: S
authors.lastname: Marketkar
authors.affiliation: Pathologist, Rhode Island Hospital, Assistant Professor of Pathology and Laboratory Medicine (Clinical), Alpert Medical School of Brown University, Providence, RI.
authors.forename: Mark
authors.initials: M
authors.lastname: LeGolvan
mesh_terms: D000784:Aortic Dissection / Q000175:diagnosis* / Q000276:immunology / Q000473:pathology; D001025:Aortitis / Q000175:diagnosis* / Q000276:immunology / Q000473:pathology; D015415:Biomarkers / Q000032:analysis; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis* / Q000097:blood; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged; D010950:Plasma Cells / Q000276:immunology*; D016896:Treatment Outcome
chemical_list: D015415:Biomarkers; D007074:Immunoglobulin G
keywords: IgG4; aortitis; plasma cells