title: Unicentric Castleman's disease associated with end stage renal disease caused by amyloidosis.
abstract: Castleman's disease (CD), also known as angiofolicular lymph node hyperplasia, is a rare heterogenous group of lymphoproliferative disorders. Histologically, it can be classified as hyaline vascular type, plasma cell type, or mixed type. Clinically two different subtypes of the CD are present: Unicentric and multicentric. Unicentric CD is generally asymptomatic and associated with hyaline vascular type, and its diagnoses depend on the localized lymphadenopathy on examination or imaging studies. However, multicentric CD presents with generalized lymphadenopathy and systemic symptoms including malaise, fever, night sweats, weight loss, and it is associated with the plasma cell type and mix type. Herein, we report a patient with unicentric CD of the plasma cell type without systemic symptoms, who developed end stage renal failure caused by amyloidosis 6 years after onset of CD.
authors.affiliation: Eray Eroglu, Ismail Kocyigit, Aydin Unal, Murat Hayri Sipahioglu, Bulent Tokgoz, Oktay Oymak, Division of Nephrology, Department of Internal Medicine, Erciyes University School of Medicine, 38039 Kayseri, Turkey.
authors.forename: Eray
authors.initials: E
authors.lastname: Eroglu
authors.affiliation: Eray Eroglu, Ismail Kocyigit, Aydin Unal, Murat Hayri Sipahioglu, Bulent Tokgoz, Oktay Oymak, Division of Nephrology, Department of Internal Medicine, Erciyes University School of Medicine, 38039 Kayseri, Turkey.
authors.forename: Ismail
authors.initials: I
authors.lastname: Kocyigit
authors.affiliation: Eray Eroglu, Ismail Kocyigit, Aydin Unal, Murat Hayri Sipahioglu, Bulent Tokgoz, Oktay Oymak, Division of Nephrology, Department of Internal Medicine, Erciyes University School of Medicine, 38039 Kayseri, Turkey.
authors.forename: Aydin
authors.initials: A
authors.lastname: Unal
authors.affiliation: Eray Eroglu, Ismail Kocyigit, Aydin Unal, Murat Hayri Sipahioglu, Bulent Tokgoz, Oktay Oymak, Division of Nephrology, Department of Internal Medicine, Erciyes University School of Medicine, 38039 Kayseri, Turkey.
authors.forename: Murat Hayri
authors.initials: MH
authors.lastname: Sipahioglu
authors.affiliation: Eray Eroglu, Ismail Kocyigit, Aydin Unal, Murat Hayri Sipahioglu, Bulent Tokgoz, Oktay Oymak, Division of Nephrology, Department of Internal Medicine, Erciyes University School of Medicine, 38039 Kayseri, Turkey.
authors.forename: Hulya
authors.initials: H
authors.lastname: Akgun
authors.affiliation: Eray Eroglu, Ismail Kocyigit, Aydin Unal, Murat Hayri Sipahioglu, Bulent Tokgoz, Oktay Oymak, Division of Nephrology, Department of Internal Medicine, Erciyes University School of Medicine, 38039 Kayseri, Turkey.
authors.forename: Leylagul
authors.initials: L
authors.lastname: Kaynar
authors.affiliation: Eray Eroglu, Ismail Kocyigit, Aydin Unal, Murat Hayri Sipahioglu, Bulent Tokgoz, Oktay Oymak, Division of Nephrology, Department of Internal Medicine, Erciyes University School of Medicine, 38039 Kayseri, Turkey.
authors.forename: Bulent
authors.initials: B
authors.lastname: Tokgoz
authors.affiliation: Eray Eroglu, Ismail Kocyigit, Aydin Unal, Murat Hayri Sipahioglu, Bulent Tokgoz, Oktay Oymak, Division of Nephrology, Department of Internal Medicine, Erciyes University School of Medicine, 38039 Kayseri, Turkey.
authors.forename: Oktay
authors.initials: O
authors.lastname: Oymak
keywords: Amyloidosis; Castleman’s disease; End stage renal disease; Inflammation; Plasma cell