title: A novel phenotypic assay of hepatitis B virus polymerase with extensive site-specific mutagenesis.
authors.affiliation: Institute for Viral Hepatitis, Key Laboratory of Molecular Biology on Infectious Diseases, Ministry of Education, the Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China.
authors.forename: Ya
authors.initials: Y
authors.lastname: Liu
authors.affiliation: Institute for Viral Hepatitis, Key Laboratory of Molecular Biology on Infectious Diseases, Ministry of Education, the Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China.
authors.forename: Ying-Ying
authors.initials: YY
authors.lastname: Luo
authors.affiliation: Institute for Viral Hepatitis, Key Laboratory of Molecular Biology on Infectious Diseases, Ministry of Education, the Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China.
authors.forename: Xue-Fei
authors.initials: XF
authors.lastname: Cai
authors.affiliation: Institute for Viral Hepatitis, Key Laboratory of Molecular Biology on Infectious Diseases, Ministry of Education, the Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China.
authors.forename: Quan-Xin
authors.initials: QX
authors.lastname: Long
authors.affiliation: Institute for Viral Hepatitis, Key Laboratory of Molecular Biology on Infectious Diseases, Ministry of Education, the Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China.
authors.forename: Chun-Yang
authors.initials: CY
authors.lastname: Gan
authors.affiliation: Institute for Viral Hepatitis, Key Laboratory of Molecular Biology on Infectious Diseases, Ministry of Education, the Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China.
authors.forename: Liu-Qing
authors.initials: LQ
authors.lastname: Yang
authors.affiliation: Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, 46202, USA.
authors.forename: Haitao
authors.initials: H
authors.lastname: Guo
authors.affiliation: Institute for Viral Hepatitis, Key Laboratory of Molecular Biology on Infectious Diseases, Ministry of Education, the Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China.|Collaborative Innovation Center for diagnosis and treatment of infectious diseases (CCID), Hangzhou, 310058, China.
authors.forename: Ai-Long
authors.initials: AL
authors.lastname: Huang
authors.affiliation: Institute for Viral Hepatitis, Key Laboratory of Molecular Biology on Infectious Diseases, Ministry of Education, the Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China. zhangwenlu@cqmu.edu.cn.
authors.forename: Wen-Lu
authors.initials: WL
authors.lastname: Zhang
authors.affiliation: Institute for Viral Hepatitis, Key Laboratory of Molecular Biology on Infectious Diseases, Ministry of Education, the Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China. hujieli1977@163.com.|Collaborative Innovation Center for diagnosis and treatment of infectious diseases (CCID), Hangzhou, 310058, China. hujieli1977@163.com.
authors.forename: Jie-Li
authors.initials: JL
authors.lastname: Hu
mesh_terms: D002460:Cell Line; D004252:DNA Mutational Analysis / Q000379:methods*; D006515:Hepatitis B virus / Q000201:enzymology* / Q000235:genetics / Q000502:physiology*; D006801:Humans; D008967:Molecular Biology / Q000379:methods; D016297:Mutagenesis, Site-Directed; D050505:Mutant Proteins / Q000235:genetics / Q000378:metabolism; D012194:RNA-Directed DNA Polymerase / Q000235:genetics* / Q000378:metabolism; D014773:Virology / Q000379:methods*; D014779:Virus Replication
chemical_list: D050505:Mutant Proteins; D012194:RNA-Directed DNA Polymerase