title: Risk factors, characteristics, and outcomes of candidemia in an adult intensive care unit in Turkey.
abstract: Thirty-six patients with candidemia and 37 control patients were included consecutively to determine the characteristics of candidemia episodes. The patients with candidemia had higher mortality with higher Sequential Organ Failure Assessment scores and frequency of use of a central venous catheter, total parenteral nutrition, and broad-spectrum antibiotics; chronic renal failure with replacement therapy; and longer stay in an intensive care unit. Candida albicans was the predominant species followed by Candida glabrata, Candida tropicalis, and Candida parapsilosis. All isolates of C glabrata were itraconazole-resistant.
authors.affiliation: Department of Infectious Disease and Clinical Microbiology, School of Medicine, Marmara University, Istanbul, Turkey. Electronic address: fetukenmez@yahoo.com.
authors.forename: Elif
authors.initials: E
authors.lastname: Tukenmez Tigen
authors.affiliation: Department of Infectious Disease and Clinical Microbiology, School of Medicine, Marmara University, Istanbul, Turkey.
authors.forename: Huseyin
authors.initials: H
authors.lastname: Bilgin
authors.affiliation: Department of Public Health, School of Medicine, Marmara University, Istanbul, Turkey.
authors.forename: Hande
authors.initials: H
authors.lastname: Perk Gurun
authors.affiliation: Department of Infectious Disease and Clinical Microbiology, Goztepe Training and Research Hospital, Istanbul Medeniyet University, Istanbul, Turkey.
authors.forename: Arzu
authors.initials: A
authors.lastname: Dogru
authors.affiliation: Department of Cardiology, School of Medicine, Marmara University, Turkey.
authors.forename: Beste
authors.initials: B
authors.lastname: Ozben
authors.affiliation: Department of Microbiology, School of Medicine, Marmara University, Turkey.
authors.forename: Nilgun
authors.initials: N
authors.lastname: Cerikcioglu
authors.affiliation: Department of Infectious Disease and Clinical Microbiology, School of Medicine, Marmara University, Istanbul, Turkey.
authors.forename: Volkan
authors.initials: V
authors.lastname: Korten
mesh_terms: D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000935:Antifungal Agents / Q000494:pharmacology; D002175:Candida / Q000187:drug effects / Q000302:isolation & purification; D058387:Candidemia / Q000382:microbiology / Q000401:mortality*; D062905:Central Venous Catheters / Q000706:statistics & numerical data; D005260:Female; D006801:Humans; D007362:Intensive Care Units / Q000706:statistics & numerical data*; D017964:Itraconazole / Q000494:pharmacology; D007902:Length of Stay / Q000706:statistics & numerical data; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D063305:Organ Dysfunction Scores; D010288:Parenteral Nutrition / Q000706:statistics & numerical data; D051437:Renal Insufficiency / Q000453:epidemiology / Q000382:microbiology; D012189:Retrospective Studies; D012307:Risk Factors; D014421:Turkey / Q000453:epidemiology
chemical_list: D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D017964:Itraconazole
keywords: Candida infection; Epidemiology; Mortality; Predisposing factors