title: Prevalence of metabolic syndrome in Chinese psoriasis patients: A hospital-based cross-sectional study.
abstract: OBJECTIVE
  Psoriasis, a chronic autoimmune skin disorder, is believed to contribute to cardiovascular diseases and metabolic syndrome. Psoriasis's association with the components of metabolic syndrome has been reported previously. However, large-scale cross-sectional studies about psoriasis and metabolic syndrome are rare in China.
  
  
  METHODS
  We assessed the prevalence of metabolic syndrome in Chinese psoriasis patients and controls.
  
  
  RESULTS
  A total of 859 psoriasis patients and 1,718 controls were recruited in an age- and sex-matched cross-sectional study. Metabolic syndrome occurred in 14.3% of the psoriasis patients as opposed to 10.0% of the control participants (P = 0.001). Psoriasis patients had a higher prevalence of overweight/obesity, hyperglycemia and dyslipidemia when compared with controls. Meanwhile, psoriasis patients with metabolic syndrome were older, and had an older age of onset and a longer disease duration when compared with those without metabolic syndrome.
  
  
  CONCLUSIONS
  The prevalence of metabolic syndrome is higher in the Chinese psoriatic population, which can favor cardiovascular events. The present study strengthens the value of treating psoriasis patients not only dealing with the skin lesions, and we suggest appropriate screening and relevant health education be carried out in the treatment of psoriasis patients.
authors.affiliation: Department of Dermatology, Peking Union Medical College Hospital, Beijing, China.
authors.forename: Xin-Yu
authors.initials: XY
authors.lastname: Gui
authors.affiliation: Department of Dermatology, Peking Union Medical College Hospital, Beijing, China.
authors.forename: Xiao-Ling
authors.initials: XL
authors.lastname: Yu
authors.affiliation: Department of Dermatology, Peking Union Medical College Hospital, Beijing, China.
authors.forename: Hong-Zhong
authors.identifier: http://orcid.org/0000-0001-6234-1554
authors.initials: HZ
authors.lastname: Jin
authors.affiliation: Department of Dermatology, Peking Union Medical College Hospital, Beijing, China.
authors.forename: Ya-Gang
authors.initials: YG
authors.lastname: Zuo
authors.affiliation: Department of Dermatology, Peking Union Medical College Hospital, Beijing, China.
authors.forename: Chao
authors.initials: C
authors.lastname: Wu
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D044466:Asian People; D002681:China / Q000453:epidemiology; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D024821:Metabolic Syndrome / Q000150:complications / Q000453:epidemiology*; D008875:Middle Aged; D015995:Prevalence; D011565:Psoriasis / Q000150:complications / Q000453:epidemiology*; D055815:Young Adult
keywords: Metabolic syndrome; Prevalence; Psoriasis