title: Ozone Treatment on Dentin Hypersensitivity Surfaces - A Pilot Study.
abstract: BACKGROUND
  Dentin hypersensitivity (DH) is a frequent condition in adults and difficult to treat. The aim of this single-blind, randomised controlled clinical trial was to investigate immediate and long-term effect of ozone treatment (Prozone, W&H NORDIC AB) for 12 seconds on hypersensitive teeth compared to placebo treatment, using a split-mouth design.
  
  
  METHODS
  26 patients (12 M, 14 F, mean age 44+ 2) were included in the study having at least two teeth with confirmed DH in different quadrants of the dentition (each subject had one test and one control tooth). A visual analogue scale (VAS) was used to measure the patients´ pain perception immediately and at a long-term follow-up three months later.
  
  
  RESULTS
  Significant reduction in pain perception from DH surfaces was demonstrated from ozone treated test teeth as well as in placebo treated control teeth. We found a moderate (16.2%) but significant pain relief (p< 0.012) over time in 57.7% of all treated teeth.
  
  
  CONCLUSIONS
  Results from this study confirm previously published results showing no significant effect of ozone treatment on hypersensitive teeth compared to placebo treatment.
authors.affiliation: Department of Dental Medicine, Cariology and Endodontology, Karolinska Institutet, Sweden.
authors.forename: Karlsson
authors.initials: K
authors.lastname: Lena
authors.affiliation: Department of Dental Medicine, Cariology and Endodontology, Karolinska Institutet, Sweden.
authors.forename: Kjaeldgaard
authors.initials: K
authors.lastname: Marianne
keywords: Dentin Hypersensitivity; Ozone; Placebo Treatment; Randomised Clinical Trial; Split-mouth Design