title: Polysaccharides in Grifola frondosa mushroom and their health promoting properties: A review.
abstract: Grifola frondosa (Dicks.) Gray is a widely consumed edible and medicinal fungus, Ancient books record that it can boost qi and fortify the spleen, moisten the lung and protect the liver. Modern people mainly use it to assist in the treatment of diabetes mellitus and various cancers. Over the past three decades, G. frondosa polysaccharides were shown to possess various promising bioactivities, mainly including antitumor and immunomodulation, anti-oxidation, anti-hyperglycemia, and meanwhile can effectively act on the skin and hematopoietic stem cells. The purpose of the present review is to provide systematically reorganized information on structural characteristics, biological activities, and structure-activity relationship of G. frondosa polysaccharides to support their further therapeutic potentials and sanitarian functions.
authors.affiliation: Hong-Hui Hospital, Xi'an Jiaotong University College of Medicine, Xi'an 710054, PR China; Key Laboratory of Resource Biology and Biotechnology in Western China (Northwest University), Ministry of Education, Xi'an 710069, PR China. Electronic address: hxrhist@163.com.
authors.forename: Xirui
authors.initials: X
authors.lastname: He
authors.affiliation: Key Laboratory of Resource Biology and Biotechnology in Western China (Northwest University), Ministry of Education, Xi'an 710069, PR China.
authors.forename: Xiaoxiao
authors.initials: X
authors.lastname: Wang
authors.affiliation: Key Laboratory of Resource Biology and Biotechnology in Western China (Northwest University), Ministry of Education, Xi'an 710069, PR China.
authors.forename: Jiacheng
authors.initials: J
authors.lastname: Fang
authors.affiliation: Hong-Hui Hospital, Xi'an Jiaotong University College of Medicine, Xi'an 710054, PR China.
authors.forename: Yu
authors.initials: Y
authors.lastname: Chang
authors.affiliation: Hong-Hui Hospital, Xi'an Jiaotong University College of Medicine, Xi'an 710054, PR China.
authors.forename: Ning
authors.initials: N
authors.lastname: Ning
authors.affiliation: Hong-Hui Hospital, Xi'an Jiaotong University College of Medicine, Xi'an 710054, PR China.
authors.forename: Hao
authors.initials: H
authors.lastname: Guo
authors.affiliation: Hong-Hui Hospital, Xi'an Jiaotong University College of Medicine, Xi'an 710054, PR China. Electronic address: huanglhlab@163.com.
authors.forename: Linhong
authors.initials: L
authors.lastname: Huang
authors.affiliation: Hong-Hui Hospital, Xi'an Jiaotong University College of Medicine, Xi'an 710054, PR China.
authors.forename: Xiaoqiang
authors.initials: X
authors.lastname: Huang
authors.affiliation: Key Laboratory of Resource Biology and Biotechnology in Western China (Northwest University), Ministry of Education, Xi'an 710069, PR China.
authors.forename: Zefeng
authors.initials: Z
authors.lastname: Zhao
mesh_terms: D000818:Animals; D062610:Fungal Polysaccharides / Q000737:chemistry* / Q000494:pharmacology*; D048691:Grifola / Q000737:chemistry*; D006262:Health; D006801:Humans; D013329:Structure-Activity Relationship
chemical_list: D062610:Fungal Polysaccharides
keywords: MD-fraction; Maitake; SX-fraction