title: A rare case report of early bioprosthetic valve thrombosis presenting with acute heart failure salvaged by thrombectomy.
abstract: BACKGROUND
  Bioprosthetic valve thrombosis is previously considered as an extremely rare complication which hasn't been systemically recognized and understood.
  
  
  METHODS
  Herein, we present an unusual case of a patient manifesting with acute heart failure, secondary to thrombus formation in a porcine aortic bioprosthesis which was implanted 11 months prior to hospitalization. Due to the patient's poor heart function and intraoperative findings, thrombectomy was performed. For our best knowledge, cases of early bioprosthetic valve thrombosis presenting with acute heart failure have seldomly been reported.
  
  
  CONCLUSIONS
  Our study reviews predisposing factors, typical echocardiographic features and treatment for bioprosthetic valve thrombosis and it should be considered as a reason for bioprosthetic malfunction. A combination of clinical and echocardiographic features can help for diagnosis preoperatively. In some certain circumstances, early reoperation can be avoided if anticoagulant therapy works.
authors.affiliation: Department of Cardiothoracic Surgery, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
authors.forename: Jingya
authors.initials: J
authors.lastname: Fan
authors.affiliation: Department of Cardiothoracic Surgery, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
authors.forename: Peng
authors.initials: P
authors.lastname: Teng
authors.affiliation: Department of Cardiothoracic Surgery, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
authors.forename: Yu
authors.initials: Y
authors.lastname: Zou
authors.affiliation: Department of Cardiothoracic Surgery, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China. tptriston@zju.edu.cn.|, Postal Address: 79#, Qingchun Road, Hangzhou, 310000, Zhejiang, China. tptriston@zju.edu.cn.
authors.forename: Liang
authors.initials: L
authors.lastname: Ma
mesh_terms: D000208:Acute Disease; D000818:Animals; D000925:Anticoagulants / Q000627:therapeutic use; D001021:Aortic Valve / Q000601:surgery*; D001705:Bioprosthesis / Q000009:adverse effects*; D004452:Echocardiography; D006331:Heart Diseases / Q000175:diagnosis / Q000209:etiology / Q000601:surgery; D006333:Heart Failure / Q000175:diagnosis / Q000209:etiology*; D006349:Heart Valve Diseases / Q000175:diagnosis / Q000601:surgery*; D006350:Heart Valve Prosthesis / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011475:Prosthesis Failure; D013552:Swine; D017131:Thrombectomy / Q000379:methods*; D013927:Thrombosis / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery
chemical_list: D000925:Anticoagulants
keywords: Aortic valve; Bioprosthetic valve thrombosis; Porcine bioprosthesis; Thrombectomy