title: A One-Pot Multicomponent 1,3-Dipolar Cycloaddition Strategy: Combinatorial Synthesis of Dihydrothiophenone-Engrafted Dispiro Hybrid Heterocycles.
abstract: The combinatorial syntheses of a library of novel dihydrothiophenone-engrafted dispiro oxindole/indenoquinoxaline-pyrrolidine/pyrrolothiazole/indolizine hybrid heterocycles have been realized through a chemo-, regio-, and stereoselective multicomponent 1,3-dipolar cycloaddition strategy.
authors.affiliation: Department of Organic Chemistry, School of Chemistry, Madurai Kamaraj University , Madurai-625021, Tamil Nadu, India.
authors.forename: Mani
authors.initials: M
authors.lastname: Anusha Rani
authors.affiliation: Department of Organic Chemistry, School of Chemistry, Madurai Kamaraj University , Madurai-625021, Tamil Nadu, India.
authors.forename: Sundaravel
authors.initials: S
authors.lastname: Vivek Kumar
authors.affiliation: Department of Organic Chemistry, School of Chemistry, Madurai Kamaraj University , Madurai-625021, Tamil Nadu, India.
authors.forename: Karuppiah
authors.initials: K
authors.lastname: Malathi
authors.affiliation: Department of Organic Chemistry, School of Chemistry, Madurai Kamaraj University , Madurai-625021, Tamil Nadu, India.
authors.forename: Muthumani
authors.initials: M
authors.lastname: Muthu
authors.affiliation: Department of Chemistry, College of Science, King Saud University , P.O. Box 2455, Riyadh 11451, Saudi Arabia.
authors.forename: Abdulrahman I
authors.initials: AI
authors.lastname: Almansour
authors.affiliation: Department of Chemistry, College of Science, King Saud University , P.O. Box 2455, Riyadh 11451, Saudi Arabia.
authors.forename: Raju
authors.initials: R
authors.lastname: Suresh Kumar
authors.affiliation: Department of Organic Chemistry, School of Chemistry, Madurai Kamaraj University , Madurai-625021, Tamil Nadu, India.
authors.forename: Raju
authors.identifier: 0000-0002-9926-7770
authors.initials: R
authors.lastname: Ranjith Kumar
mesh_terms: D020650:Combinatorial Chemistry Techniques; D061565:Cycloaddition Reaction; D000072471:Heterocyclic Compounds, Fused-Ring / Q000138:chemical synthesis*; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D015394:Molecular Structure; D054852:Small Molecule Libraries / Q000138:chemical synthesis*; D013141:Spiro Compounds / Q000138:chemical synthesis*; D013237:Stereoisomerism; D013329:Structure-Activity Relationship; D013876:Thiophenes / Q000138:chemical synthesis*
chemical_list: D000072471:Heterocyclic Compounds, Fused-Ring; D054852:Small Molecule Libraries; D013141:Spiro Compounds; D013876:Thiophenes
keywords: 1,3-dipolar cycloaddition; azomethine ylide; dihydrothiophen-3(2H)-ones; dispiro heterocycles; multicomponent reaction