title: TREATMENT OF PULMONICOLA COCHLEOTREMA INFECTION WITH IVERMECTIN-PRAZIQUANTEL COMBINATION IN AN ANTILLEAN MANATEE (TRICHECHUS MANATUS MANATUS).
abstract: The aim of this study was to report the use of an oral combination of ivermectin plus praziquantel in the treatment of a Pulmonicola cochleotrema in an Antillean manatee ( Trichechus manatus manatus). A female manatee was found exhibiting respiratory changes and the presence of parasites in the nares. Based on clinical manifestations presented by the manatee, a symptomatic therapeutic protocol was employed, which included an anthelmintic treatment using a combination of ivermectin plus praziquantel. The parasites retrieved were identified as P. cochleotrema. The fourth day after the onset of the therapeutic protocol, the clinical signs declined and on the seventh day posttreatment no clinical signs were observed. This is the first time a therapeutic protocol of ivermectin plus praziquantel has been used in the treatment of P. cochleotrema in manatees.
authors.forename: João Carlos Gomes
authors.initials: JC
authors.lastname: Borges
authors.forename: Larissa Molinari
authors.initials: LM
authors.lastname: Jung
authors.forename: Sebastião Silva Dos
authors.initials: SS
authors.lastname: Santos
authors.forename: Vitor Luz
authors.initials: VL
authors.lastname: Carvalho
authors.forename: Rafael Antonio Nascimento
authors.initials: RA
authors.lastname: Ramos
authors.forename: Leucio Câmara
authors.initials: LC
authors.lastname: Alves
mesh_terms: D000818:Animals; D000871:Anthelmintics / Q000008:administration & dosage / Q000627:therapeutic use; D005260:Female; D007559:Ivermectin / Q000008:administration & dosage / Q000627:therapeutic use*; D011223:Praziquantel / Q000008:administration & dosage / Q000627:therapeutic use*; D014200:Trematoda / Q000145:classification*; D014201:Trematode Infections / Q000188:drug therapy / Q000662:veterinary*; D020457:Trichechus manatus
chemical_list: D000871:Anthelmintics; D011223:Praziquantel; D007559:Ivermectin
keywords: Aquatic mammals; clinical signs; conservation; helminthes; trematode