title: Hemophagocytic lymphohistiocytosis secondary to hemodialysis catheter-related blood stream infection.
abstract: A 57-year-old man on dialysis presented with fever due toPseudomonassepticemia. Workup revealed very high triglycerides and serum ferritin levels. A bone marrow examination showed hemophagocytosis. A diagnosis of hemophagocytic lymphohistiocytosis (HLH) was made and steroids were started. He was put on automated peritoneal dialysis. Patients' condition continued to deteriorate and he succumbed to his illness. This case illustrates the development of HLH secondary to infections which are increasingly being recognized in the literature. Often this diagnosis is missed as it becomes difficult to differentiate between sepsis and HLH. The presence of high ferritin, hypertriglyceridemia, and hemophagocytosis in the bone marrow confirms the diagnosis.
authors.affiliation: Department of Nephrology, Yashoda Hospitals, Secunderabad, Telangana, India.
authors.forename: U
authors.initials: U
authors.lastname: Anandh
authors.affiliation: Department of Laboratory Medicine, Yashoda Hospitals, Secunderabad, Telangana, India.
authors.forename: S
authors.initials: S
authors.lastname: Johari
authors.affiliation: Department of Clinical Hematology and Oncology, Yashoda Hospitals, Secunderabad, Telangana, India.
authors.forename: B
authors.initials: B
authors.lastname: Vaswani
keywords: Catheter infection; hemodialysis; hemophagocytic lymphohistiocytosis