title: [Management of acute anaphylaxis in clinical practice in the context of the guidelines].
abstract: Anaphylaxis is a rapidly progressing, life-threatening allergic reaction that needs rapid diagnosis and treatment. Recent research has brought new information about the increasing incidence of anaphylaxis. Nevertheless, the prevalence and incidence of anaphylaxis are difficult to estimate due to the lack of consensus on the definition of anaphylaxis, differences between the population groups analysed, and use of different data collection methods. The most common triggers of anaphylaxis are food allergens, insect stings, and drugs. The serum tryptase level serves as a diagnostic indicator of anaphylaxis. In patients with normal serum tryptase levels, other inflammatory mediators need to be considered. Epinephrine is still the drug of choice for the therapy of severe anaphylaxis. The authors present new information about anaphylaxis from the recently published literature and/or guidelinesKEYWORDS: anaphylaxis - epinephrine - guidelines - histamine - tryptase.
authors.forename: P Ch
authors.initials: PC
authors.lastname: Cmorej
authors.forename: M
authors.initials: M
authors.lastname: Nesvadba
authors.forename: R
authors.initials: R
authors.lastname: Babeľa
authors.forename: O
authors.initials: O
authors.lastname: Slowik
authors.forename: R
authors.initials: R
authors.lastname: Didič
mesh_terms: D000707:Anaphylaxis / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D004837:Epinephrine / Q000627:therapeutic use; D006801:Humans; D007299:Insect Bites and Stings / Q000150:complications; D053802:Tryptases / Q000097:blood
chemical_list: D053802:Tryptases; D004837:Epinephrine