title: Risk Factors for Developing Scoliosis in Cerebral Palsy: A Cross-Sectional Descriptive Study.
abstract: This study aims to identify the risk factors leading to the development of severe scoliosis among children with cerebral palsy. A cross-sectional descriptive study of 70 children (aged 12-18 years) with severe spastic and/or dystonic cerebral palsy treated in a single specialist unit is described. Statistical analysis included Fisher exact test and logistic regression analysis to identify risk factors. Severe scoliosis is more likely to occur in patients with intractable epilepsy ( P = .008), poor gross motor functional assessment scores ( P = .018), limb spasticity ( P = .045), a history of previous hip surgery ( P = .048), and nonambulatory patients ( P = .013). Logistic regression model confirms the major risk factors are previous hip surgery ( P = .001), moderate to severe epilepsy ( P = .007), and female gender ( P = .03). History of previous hip surgery, intractable epilepsy, and female gender are predictors of developing severe scoliosis in children with cerebral palsy. This knowledge should aid in the early diagnosis of scoliosis and timely referral to specialist services.
authors.affiliation: 1 Department of Paediatric Orthopaedic Surgery, Lenval University Paediatric Hospital of Nice, Nice, France.
authors.forename: Carlo M
authors.initials: CM
authors.lastname: Bertoncelli
authors.affiliation: 1 Department of Paediatric Orthopaedic Surgery, Lenval University Paediatric Hospital of Nice, Nice, France.
authors.forename: Federico
authors.initials: F
authors.lastname: Solla
authors.affiliation: 2 Scottish National Spine Deformity Centre, Royal Hospital for Sick Children, University of Edinburgh, Edinburgh, United Kingdom.
authors.forename: Peter R
authors.initials: PR
authors.lastname: Loughenbury
authors.affiliation: 2 Scottish National Spine Deformity Centre, Royal Hospital for Sick Children, University of Edinburgh, Edinburgh, United Kingdom.
authors.forename: Athanasios I
authors.initials: AI
authors.lastname: Tsirikos
authors.affiliation: 3 Department of Information Engineering, Computer Science and Mathematics, University of L'Aquila, L'Aquila, Italy.
authors.forename: Domenico
authors.initials: D
authors.lastname: Bertoncelli
authors.affiliation: 1 Department of Paediatric Orthopaedic Surgery, Lenval University Paediatric Hospital of Nice, Nice, France.
authors.forename: Virginie
authors.initials: V
authors.lastname: Rampal
mesh_terms: D000293:Adolescent; D002547:Cerebral Palsy / Q000150:complications* / Q000503:physiopathology; D002648:Child; D003430:Cross-Sectional Studies; D004827:Epilepsy / Q000150:complications* / Q000503:physiopathology; D005260:Female; D006801:Humans; D008297:Male; D012307:Risk Factors; D012600:Scoliosis / Q000209:etiology* / Q000503:physiopathology; D012737:Sex Factors
keywords: cerebral palsy; epilepsy; risk factors; scoliosis; spasticity; spinal fusion