title: Self-healing juvenile cutaneous mucinosis.
abstract: Girl, aged 4 years old, began the disease with pain of the lower extremities, fever up to 38°C and signs of upper airway infection. Then the patient developed oedema and redness of the whole face, thickened skin, subcutaneous nodular foldings of the frontal, occipital, cervical and axillary regions, extensor areas of the joints; fine, hard whitish nodules in the frontal region and over interphalangeal joints of the hands, pruritus; oedemas of the ankles, knees and joints of the hands, cervical lymphadenopathy and hepatomegaly. Blood tests at the moment of the diagnosis revealed elevation of markers of inflammation as ESR and CRP, leukocytosis, thrombocytosis, hypoalbuminemia, and hyper-alfa-2-globulinemia. Histopathological examination of the skin biopsy specimen and subcutaneous tissue revealed myxoid subcutaneous tissue located under the dermis and a section consisting of myxoid mesenchymal tissue with inflammatory infiltration by histiocytic cells. The presence of acid mucopolysaccharides in fields of the myxoid tissue was also observed. The self-healing juvenile cutaneous mucinosis (SJCM) was diagnosed.
authors.affiliation: Clinic and Polyclinic of Developmental-Age Rheumatology, National Institute of Geriatrics, Rheumatology and Rehabilitation, Warsaw, Poland.
authors.forename: Beata
authors.initials: B
authors.lastname: Kołodziejczyk
authors.affiliation: Clinic and Polyclinic of Developmental-Age Rheumatology, National Institute of Geriatrics, Rheumatology and Rehabilitation, Warsaw, Poland.
authors.forename: Agnieszka
authors.initials: A
authors.lastname: Gazda
authors.affiliation: Clinic and Polyclinic of Developmental-Age Rheumatology, National Institute of Geriatrics, Rheumatology and Rehabilitation, Warsaw, Poland.
authors.forename: Elżbieta
authors.initials: E
authors.lastname: Hernik
authors.affiliation: Clinic and Polyclinic of Developmental-Age Rheumatology, National Institute of Geriatrics, Rheumatology and Rehabilitation, Warsaw, Poland.
authors.forename: Izabela
authors.initials: I
authors.lastname: Szczygielska
authors.affiliation: Clinic and Polyclinic of Developmental-Age Rheumatology, National Institute of Geriatrics, Rheumatology and Rehabilitation, Warsaw, Poland.
authors.forename: Lidia
authors.initials: L
authors.lastname: Rutkowska-Sak
authors.affiliation: Department of Pathology National Institute of Geriatrics, Rheumatology and Rehabilitation, Warsaw, Poland.
authors.forename: Marta Legatowicz
authors.initials: ML
authors.lastname: Koprowska
keywords: lichen myxedematous; mucin deposits; papular or nodular eruption on the skin; self-healing juvenile cutaneous mucinosis