title: Effects of Isolation by Continental Islands in the Seto Inland Sea, Japan, on Genetic Diversity of the Large Japanese Field Mouse, Apodemus speciosus (Rodentia: Muridae), Inferred from the Mitochondrial Dloop Region.
abstract: To study the effects of post-glacial isolation by islands on population genetic diversity and differentiation of the large Japanese field mouse, Apodemus speciosus, we examined partial nucleotide sequences of the mitochondrial Dloop region (ca. 300 bp) in 231 individuals collected from islands in the Seto Inland Sea and adjacent regions on Honshu and Shikoku Islands in the western part of the Japanese archipelago. Molecular phylogenetic and network analyses showed that haplotypes in each island tended to form monophyletic groups, while those in Honshu and Shikoku (the major Japanese islands) showed scattered relationships and were connected with island haplotypes. These observations suggest that a set of Honshu and Shikoku haplotypes became the ancestral lineages of the island population. No gene flow was detected among island populations, indicating that independent evolution occurred on each island, without the influence of human activities, since the establishment of the islands in the Holocene. Population genetic diversities on each island were lower than those on Honshu and Shikoku. Comparison between genetic diversity and island area size showed positive correlations and supported the suggestion that genetic drift is a major factor that shaped the current haplotype constitution of the islands in the Seto Inland Sea.
authors.affiliation: 1 Laboratory of Animal Cell Technology, Faculty of Life Science and Technology, Fukuyama University, Higashimura-cho, Aza, Sanzo, 985, Fukuyama 729-0292, Japan.
authors.forename: Jun J
authors.initials: JJ
authors.lastname: Sato
authors.affiliation: 1 Laboratory of Animal Cell Technology, Faculty of Life Science and Technology, Fukuyama University, Higashimura-cho, Aza, Sanzo, 985, Fukuyama 729-0292, Japan.
authors.forename: Yurina
authors.initials: Y
authors.lastname: Tasaka
authors.affiliation: 1 Laboratory of Animal Cell Technology, Faculty of Life Science and Technology, Fukuyama University, Higashimura-cho, Aza, Sanzo, 985, Fukuyama 729-0292, Japan.
authors.forename: Ryoya
authors.initials: R
authors.lastname: Tasaka
authors.affiliation: 1 Laboratory of Animal Cell Technology, Faculty of Life Science and Technology, Fukuyama University, Higashimura-cho, Aza, Sanzo, 985, Fukuyama 729-0292, Japan.
authors.forename: Kentaro
authors.initials: K
authors.lastname: Gunji
authors.affiliation: 1 Laboratory of Animal Cell Technology, Faculty of Life Science and Technology, Fukuyama University, Higashimura-cho, Aza, Sanzo, 985, Fukuyama 729-0292, Japan.
authors.forename: Yuya
authors.initials: Y
authors.lastname: Yamamoto
authors.affiliation: 2 Department of Anatomy, School of Dentistry, Aichi-Gakuin University, Kusumoto-cho, Chikusa-ku, Nagoya 464-8650, Japan.
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Takada
authors.affiliation: 2 Department of Anatomy, School of Dentistry, Aichi-Gakuin University, Kusumoto-cho, Chikusa-ku, Nagoya 464-8650, Japan.
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Uematsu
authors.affiliation: 3 Department of Dental Hygiene, Aichi-Gakuin University, Kusumoto-cho, Chikusa-ku, Nagoya 464-8650, Japan.
authors.forename: Eiichi
authors.initials: E
authors.lastname: Sakai
authors.affiliation: 4 Jonan, Fujisawa 251-0057, Japan.
authors.forename: Takashi
authors.initials: T
authors.lastname: Tateishi
authors.affiliation: 1 Laboratory of Animal Cell Technology, Faculty of Life Science and Technology, Fukuyama University, Higashimura-cho, Aza, Sanzo, 985, Fukuyama 729-0292, Japan.
authors.forename: Yasunori
authors.initials: Y
authors.lastname: Yamaguchi
mesh_terms: D063147:Animal Distribution / Q000502:physiology*; D000818:Animals; D001483:Base Sequence; D004272:DNA, Mitochondrial / Q000235:genetics*; D014644:Genetic Variation; D006239:Haplotypes; D062312:Islands; D007564:Japan; D051189:Murinae / Q000235:genetics*; D010624:Phenelzine; D010802:Phylogeny; D011485:Protein Binding
chemical_list: D004272:DNA, Mitochondrial; D010624:Phenelzine
keywords: Seto Inland Sea; field mice; genetic diversity; island biogeography; mitochondrial DNA