title: Pathophysiology of Traumatic Brain Injury.
abstract: Traumatic brain injury (TBI) has become the signature injury of the military conflict in Iraq and Afghanistan and also has a high rate of occurrence in civilian populations in the United States. Although the effects of a moderate to severe brain injury have been investigated for decades, the chronic effects of single and repetitive mild TBI are just beginning to be investigated. Data suggest that the different types and severities of TBI have unique long-term outcomes and thus may represent different types of diseases. Therefore, this review outlines the causes, incidence, symptoms, and pathophysiology of mild, moderate, and severe TBI.
authors.affiliation: Department of Physical Medicine and Rehabilitation, Virginia Commonwealth University, 1223 East Marshall Street, Richmond, VA 23298, USA. Electronic address: Kirsty.dixon@vcuhealth.org.
authors.forename: Kirsty J
authors.initials: KJ
authors.lastname: Dixon
mesh_terms: D055826:Afghan Campaign 2001-; D001753:Blast Injuries / Q000150:complications / Q000473:pathology; D001924:Brain Concussion / Q000209:etiology / Q000473:pathology; D000070642:Brain Injuries, Traumatic / Q000503:physiopathology*; D006801:Humans; D015601:Injury Severity Score; D054542:Iraq War, 2003-2011; D014481:United States
keywords: Blast TBI; Concussion; Mild TBI; Pathophysiology; Symptoms; TBI; Traumatic brain injury