title: Protein and Calorie Requirements Associated With the Presence of Obesity.
abstract: Obesity compounds the metabolic response to critical illness and increases the risk for overfeeding complications due to its comorbidities. Hypocaloric, high-protein nutrition therapy affords the hospitalized patient with obesity the opportunity to achieve net protein anabolism with a reduced risk of overfeeding complications. The intent of this review is to provide the theoretical framework for development of a hypocaloric high-protein regimen, scientific evidence to support this mode of therapy, and unique considerations for its use in specialized subpopulations. Macronutrient goals and practical suggestions for patient monitoring are given.
authors.affiliation: 1 Department of Clinical Pharmacy, University of Tennessee College of Pharmacy, Memphis, Tennessee, USA.
authors.forename: Roland N
authors.initials: RN
authors.lastname: Dickerson
authors.affiliation: 2 Division of Pulmonary & Critical Care Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
authors.forename: Jayshil J
authors.initials: JJ
authors.lastname: Patel
authors.affiliation: 3 Departments of Medicine and Pharmacology & Toxicology, University of Louisville School of Medicine, Louisville, Kentucky, USA.
authors.forename: Craig J
authors.initials: CJ
authors.lastname: McClain
mesh_terms: D031204:Caloric Restriction; D016638:Critical Illness; D004044:Dietary Proteins; D006801:Humans; D009751:Nutritional Requirements; D009765:Obesity
chemical_list: D004044:Dietary Proteins
keywords: clinical outcomes; critical illness; enteral nutrition; nitrogen balance; obesity; parenteral nutrition