title: [Increased heart rate as a risk factor and treatment target in patients with heart failure].
abstract: Numerous epidemiological studies have shown that a high resting heart rate is associated with an increased cardiovascular morbidity and mortality, particularly in heart failure. The resting heart rate is not only a risk marker in heart failure, but it is also a risk factor, i.e., modifying heart rate also modifies the risk. Chronotropic drugs have shown benefits in terms of morbidity and mortality. Nevertheless, there is a major difference between the recommended heart rate and the patientsâ€™ everyday life heart rate. Indeed, even if the proportion of heart failure patients on beta-blockers is satisfactory, the number of patients with an optimal heart rate remains insufficient. The aim of this article is to examine the deleterious effect of an elevated resting heart rate in heart failure with systolic dysfunction, in order to overcome the therapeutic inertia and to improve the outcome in this patient group.
authors.affiliation: Service de Cardiologie, CHU de Liège, Site Sart Tilman, Liège, Belgique.
authors.forename: J
authors.initials: J
authors.lastname: Tridetti
authors.affiliation: Service de Cardiologie, CHU de Liège, Site Sart Tilman, Liège, Belgique.
authors.forename: F
authors.initials: F
authors.lastname: Krzesinski
authors.affiliation: Service de Cardiologie, CHU de Liège, Site Sart Tilman, Liège, Belgique.
authors.forename: V
authors.initials: V
authors.lastname: D'orio
authors.affiliation: Service de Cardiologie, CHU de Liège, Site Sart Tilman, Liège, Belgique.
authors.forename: A
authors.initials: A
authors.lastname: Ancion
authors.affiliation: Service de Cardiologie, CHU de Liège, Site Sart Tilman, Liège, Belgique.
authors.forename: P
authors.initials: P
authors.lastname: Lancellotti
authors.affiliation: Service de Cardiologie, CHU de Liège, Site Sart Tilman, Liège, Belgique.
authors.forename: L
authors.initials: L
authors.lastname: Piérard
mesh_terms: D006333:Heart Failure / Q000188:drug therapy* / Q000503:physiopathology*; D006339:Heart Rate; D006801:Humans; D012307:Risk Factors
keywords:  Heart failure ;  Heart rate ;  Telemedicine ;  Therapeutic targets 