title: A case of posterior cortical atrophy with vertical neglect.
abstract: Posterior cortical atrophy (PCA) is a syndrome caused by a neurodegenerative disease that often presents with visuospatial deficits, and can be debilitating. PCA is often characterized by elements of Balint's syndrome and dyslexia. The most common underlying pathology has been found to be Alzheimer's disease. Signs of horizontal neglect are frequently associated with PCA, but the presence of vertical (or altitudinal) neglect has not yet been reported in a patient with PCA or other forms of neurodegenerative dementia. In this paper, we present a patient with PCA who on vertical line bisection and cancellation tests revealed upper altitudinal spatial neglect. Detection of this abnormality may have important implications for diagnosis, therapeutic interventions, and patient safety.
authors.affiliation: a Comprehensive Center for Brain Health and Memory , Memorial Neuroscience Institute , Hollywood , FL , USA.
authors.forename: Hilary
authors.initials: H
authors.lastname: Glazer
authors.affiliation: b Department of Neurology and Center for Neuropsychological Studies , University of Florida , Gainesville , Florida , USA.|c Florida Department of Elder Affairs , Alzheimer's Disease Initiative, University of Florida Cognitive and Memory Disorder Clinics , Gainesville , Florida , USA.
authors.forename: Leila
authors.initials: L
authors.lastname: Saadatpour
authors.affiliation: b Department of Neurology and Center for Neuropsychological Studies , University of Florida , Gainesville , Florida , USA.|c Florida Department of Elder Affairs , Alzheimer's Disease Initiative, University of Florida Cognitive and Memory Disorder Clinics , Gainesville , Florida , USA.|d Department of Elder Affairs, National Institutes of Health/National Institute of Aging 1Florida , Alzheimer's Disease Research Center , Gainesville , Florida , USA.
authors.forename: Leilani
authors.initials: L
authors.lastname: Doty
authors.affiliation: b Department of Neurology and Center for Neuropsychological Studies , University of Florida , Gainesville , Florida , USA.|c Florida Department of Elder Affairs , Alzheimer's Disease Initiative, University of Florida Cognitive and Memory Disorder Clinics , Gainesville , Florida , USA.|d Department of Elder Affairs, National Institutes of Health/National Institute of Aging 1Florida , Alzheimer's Disease Research Center , Gainesville , Florida , USA.|e Department of Neurology , Malcom Randall Veterans Affairs Medical Center , Gainesville , FL , USA.
authors.forename: Kenneth M
authors.initials: KM
authors.lastname: Heilman
mesh_terms: D000368:Aged; D001284:Atrophy / Q000150:complications / Q000000981:diagnostic imaging / Q000473:pathology; D001927:Brain Diseases / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology*; D002540:Cerebral Cortex / Q000000981:diagnostic imaging / Q000473:pathology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009460:Neurologic Examination; D009483:Neuropsychological Tests; D010468:Perceptual Disorders / Q000150:complications* / Q000000981:diagnostic imaging; D014796:Visual Perception / Q000502:physiology*
keywords: Alzheimer’s disease; Balint’s syndrome; Vertical neglect; neurodegenerative; posterior cortical atrophy