title: Remote Ischemic Conditioning in Elective PCI?
abstract: This review examines the rationale for using remote ischemic conditioning (RIC) in elective percutaneous coronary intervention (PCI) to prevent procedure-related ischemia-reperfusion injury and justifies the importance of periprocedural biomarker elevation following elective PCI as a valid target for RIC. We review the evidence for the use of RIC as a treatment in this setting and document the salutary rules that must be followed to successfully translate RIC for clinical benefit.
authors.affiliation: 1 Department of Interventional Cardiology, Papworth Hospital, Papworth Everard, Cambridge, UK.
authors.forename: Joel P
authors.initials: JP
authors.lastname: Giblett
authors.affiliation: 1 Department of Interventional Cardiology, Papworth Hospital, Papworth Everard, Cambridge, UK.
authors.forename: Stephen P
authors.initials: SP
authors.lastname: Hoole
mesh_terms: D000818:Animals; D006801:Humans; D019194:Ischemic Preconditioning / Q000009:adverse effects / Q000379:methods*; D035002:Lower Extremity / Q000098:blood supply*; D009203:Myocardial Infarction / Q000209:etiology / Q000473:pathology / Q000517:prevention & control*; D015428:Myocardial Reperfusion Injury / Q000209:etiology / Q000473:pathology / Q000517:prevention & control*; D009206:Myocardium / Q000473:pathology; D062645:Percutaneous Coronary Intervention / Q000009:adverse effects*; D065840:Protective Factors; D012039:Regional Blood Flow; D012307:Risk Factors; D016896:Treatment Outcome
keywords: PCI-associated myocardial infarction; ischemia–reperfusion injury; percutaneous coronary intervention; remote ischemic conditioning