title: Anatomo-radiological correlation using 18-FDG-PET in abdominal sepsis model in rats. A preliminary study.
abstract: To examine a correlation of micro-PET images with photographic images of the digestive organs in abdominal sepsis model.
  Male Wistar rats weighing 265±18g were used. Abdominal sepsis was induced by ligature and cecal puncture. Micro-PET Images from abdominal cavity septic foci were obtained using 18-Fluoro-deoxyglucose, looking for a correlation with photographic images of abdominal cavity organs. Pearson's correlation test was used.
  The mean standard uptake values (SUV) and lesion areas were 2.58±0.63SUVbwg/ml and 546.87±300.95mm2, respectively. There was a strong positive correlation between the two variables (r=0.863, p=0.137), which resulted in a coefficient of determination r2?0.75, meaning that 75% of SUV variation is explained by the lesion areas of digestive organs.
  Micro-PET allows high throughput assessment of lesion count and volume in pre-clinical rat model of CPL abdominal sepsis.
authors.affiliation: Fellow PhD degree, Postgraduate Program in Health Sciences, Universidade Federal do Rio Grande do Norte (UFRN), Natal-RN, Brazil. Acquisition and interpretation of data, technical procedures, manuscript preparation.
authors.forename: Ítalo Medeiros
authors.initials: ÍM
authors.lastname: Azevedo
authors.affiliation: Fellow PhD degree, Postgraduate Program in Health Sciences, Universidade Federal do Rio Grande do Norte (UFRN), Natal-RN, Brazil. Acquisition and interpretation of data, technical procedures, manuscript preparation.
authors.forename: Marília Daniela Ferreira
authors.initials: MD
authors.lastname: Carvalho
authors.affiliation: Fellow Master degree, Postgraduate Program in Health Sciences, UFRN, Natal-RN, Brazil. Acquisition and interpretation of data, technical procedures.
authors.forename: Rafael Pereira
authors.initials: RP
authors.lastname: Nascimento
authors.affiliation: PhD, Radiology Institute of Natal, Brazil. Analysis and interpretation of data, technical procedures, critical revision.
authors.forename: Robson
authors.initials: R
authors.lastname: Macedo
authors.affiliation: Graduate student, Institutional Program of Scientifical Initiation, UFRN, Natal-RN, Brazil. Acquisition of data, technical procedures, manuscript preparation.
authors.forename: Mônica Raquel de Souza
authors.initials: MR
authors.lastname: Aquino
authors.affiliation: Full Professor, Chairman, Nucleus of Experimental Surgery, UFRN, Natal-RN, Brazil. CNPq/PQ.2 fellowship. Conception, design, intellectual and scientific content of the study; analysis and interpretation of data; critical revision.
authors.forename: Aldo Cunha
authors.initials: AC
authors.lastname: Medeiros
mesh_terms: D000818:Animals; D004064:Digestive System / Q000000981:diagnostic imaging / Q000473:pathology; D004195:Disease Models, Animal; D019788:Fluorodeoxyglucose F18; D059413:Intraabdominal Infections / Q000000981:diagnostic imaging* / Q000473:pathology; D008297:Male; D010781:Photography / Q000379:methods; D049268:Positron-Emission Tomography / Q000379:methods*; D019275:Radiopharmaceuticals; D017208:Rats, Wistar; D015203:Reproducibility of Results; D018805:Sepsis / Q000000981:diagnostic imaging* / Q000473:pathology; D013997:Time Factors
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18