title: Pseudomembranous tracheitis caused byAspergillus fumigatusin the setting of high grade T-cell lymphoma.
abstract: Pseudomembranous tracheitis (PMT) is a rare condition most commonly caused by fungal or bacterial infection that is characterized by a pseudomembrane that partially or completely covers the tracheobronchial tree. PMT is most commonly found in immunocompromised patient populations, such as post-chemotherapy, AIDS, post-transplant and hematological malignancies. Due to its rarity, PMT is often not included in the differential diagnosis. This case describes a 65 year old male with persistent fever and refractory cough despite high dose empiric antibiotics. Subsequent bronchoscopy with biopsy revealed pseudomembranous tracheitis due toAspergillus fumigatusin the setting of T-cell lymphoma. PMT should be considered in the differential diagnosis of refractory cough in the immunocompromised population. However, it has been described in patients with nonspecific respiratory symptoms such as dyspnea, cough, and other airway issues.
authors.affiliation: Northwell Health, Department of Infectious Diseases, 400 Community Drive, Manhasset, NY 11030, United States.
authors.forename: Prashant
authors.initials: P
authors.lastname: Malhotra
authors.affiliation: Northwell Health, Department of Pulmonary, Critical Care and Sleep Medicine, 410 Lakeville Rd., New Hyde Park, NY 11040, United States.
authors.forename: Karan
authors.initials: K
authors.lastname: Singh
authors.affiliation: Northwell Health, Department of Pulmonary, Critical Care and Sleep Medicine, 410 Lakeville Rd., New Hyde Park, NY 11040, United States.
authors.forename: Paul
authors.initials: P
authors.lastname: Gill
authors.affiliation: Northwell Health, Department of Pulmonary, Critical Care and Sleep Medicine, 410 Lakeville Rd., New Hyde Park, NY 11040, United States.
authors.forename: Sonu
authors.initials: S
authors.lastname: Sahni
authors.affiliation: Northwell Health, Department of Pulmonary, Critical Care and Sleep Medicine, 410 Lakeville Rd., New Hyde Park, NY 11040, United States.
authors.forename: Mina
authors.initials: M
authors.lastname: Makaryus
authors.affiliation: Northwell Health, Department of Pulmonary, Critical Care and Sleep Medicine, 410 Lakeville Rd., New Hyde Park, NY 11040, United States.
authors.forename: Arunabh
authors.initials: A
authors.lastname: Talwar
keywords: Aspergillus; Bronchoscopy; Chronic cough; Immunocompromised; Pseudomembranous tracheitis; T-cell lymphoma