title: Brain iron accumulation in Wilson's disease: A longitudinal imaging case study during anticopper treatment using 7.0T MRI and transcranial sonography.
abstract: 5 Technical Efficacy: Stage 3 J. Magn. Reson. Imaging 2018;47:282-285.
authors.affiliation: Department of Neurology and Center of Clinical Neuroscience, Charles University, 1st Faculty of Medicine and General University Hospital, Prague, Czech Republic.|Department of Radiology, Charles University, 1st Faculty of Medicine and General University Hospital, Prague, Czech Republic.
authors.forename: Petr
authors.identifier: 0000-0003-4877-9642
authors.initials: P
authors.lastname: Dusek
authors.affiliation: Department of Neurology and Center of Clinical Neuroscience, Charles University, 1st Faculty of Medicine and General University Hospital, Prague, Czech Republic.|Department of Nursing, Faculty of Health Science, Palacky University Olomouc, Czech Republic.
authors.forename: David
authors.initials: D
authors.lastname: Skoloudik
authors.affiliation: Department of Neurology and Center of Clinical Neuroscience, Charles University, 1st Faculty of Medicine and General University Hospital, Prague, Czech Republic.
authors.forename: Jana
authors.initials: J
authors.lastname: Maskova
authors.affiliation: Berlin Ultrahigh Field Facility (B.U.F.F.), Max-Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany.
authors.forename: Till
authors.initials: T
authors.lastname: Huelnhagen
authors.affiliation: 4th Department of Internal Medicine, Charles University in Prague, 1st Faculty of Medicine and General University Hospital, Prague, Czech Republic.
authors.forename: Radan
authors.initials: R
authors.lastname: Bruha
authors.affiliation: Department of Pediatrics and Adolescent Medicine, Charles University in Prague, 1st Faculty of Medicine and General University Hospital, Prague, Czech Republic.
authors.forename: Daniela
authors.initials: D
authors.lastname: Zahorakova
authors.affiliation: Berlin Ultrahigh Field Facility (B.U.F.F.), Max-Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany.|Experimental and Clinical Research Center, Charité-Universitätsmedizin Berlin and Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany.
authors.forename: Thoralf
authors.initials: T
authors.lastname: Niendorf
authors.affiliation: Department of Neurology and Center of Clinical Neuroscience, Charles University, 1st Faculty of Medicine and General University Hospital, Prague, Czech Republic.
authors.forename: Evzen
authors.initials: E
authors.lastname: Ruzicka
authors.affiliation: Department of Neurology, Ludwig-Maximilians-University, Munich, Germany.
authors.forename: Susanne A
authors.initials: SA
authors.lastname: Schneider
authors.affiliation: Medical Imaging Analysis Center AG and qbig, Department of Biomedical Engineering, University Basel, Basel, Switzerland.|NeuroCure Clinical Research Center, Charité-Universitätsmedizin Berlin, Berlin, Germany.
authors.forename: Jens
authors.initials: J
authors.lastname: Wuerfel
mesh_terms: D000293:Adolescent; D000328:Adult; D016022:Case-Control Studies; D002614:Chelating Agents / Q000009:adverse effects / Q000627:therapeutic use; D003300:Copper / Q000032:analysis*; D005260:Female; D066128:Gray Matter / Q000000981:diagnostic imaging / Q000187:drug effects; D006527:Hepatolenticular Degeneration / Q000000981:diagnostic imaging* / Q000188:drug therapy* / Q000378:metabolism; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007501:Iron / Q000032:analysis / Q000627:therapeutic use*; D008137:Longitudinal Studies; D008279:Magnetic Resonance Imaging; D008297:Male; D010396:Penicillamine / Q000009:adverse effects / Q000627:therapeutic use; D013997:Time Factors; D014018:Tissue Distribution; D017585:Ultrasonography, Doppler, Transcranial; D055815:Young Adult
chemical_list: D002614:Chelating Agents; D003300:Copper; D007501:Iron; D010396:Penicillamine
keywords: Wilson's disease; iron accumulation; relaxometry; transcranial sonography; ultra-high field MRI