title: Stroke of bad luck?
abstract: We hypothesized that distinct acute right hemisphere lesions disrupt separate components of valuation and emotional response to winning and losing money and of emotional empathy in observing a partner win or lose money. We measured skin conductance response (SCR) and ratings of emotions when acute right hemisphere stroke patients or healthy controls won or lost money in roulette, or when they watched a partner win or lose. Our results showed that percentage of damage after stroke to right anterior insula and frontal operculum negatively correlated with both SCR to winning and losing and difference between rating wins versus losses.
authors.affiliation: a Departments of Neurology , Johns Hopkins University School of Medicine , Baltimore , MD , USA.
authors.forename: Eun Hye
authors.initials: EH
authors.lastname: Kim
authors.affiliation: b Departments of Neurosurgery , Johns Hopkins University School of Medicine , Baltimore , MD , USA.
authors.forename: Jui-Hong
authors.initials: JH
authors.lastname: Chien
authors.affiliation: b Departments of Neurosurgery , Johns Hopkins University School of Medicine , Baltimore , MD , USA.
authors.forename: Chang-Chia
authors.initials: CC
authors.lastname: Liu
authors.affiliation: c Whiting School of Engineering , Johns Hopkins University , Baltimore , MD , USA.
authors.forename: Kumiko
authors.initials: K
authors.lastname: Oishi
authors.affiliation: d Departments of Radiology , Johns Hopkins University School of Medicine , Baltimore , MD , USA.
authors.forename: Kenichi
authors.initials: K
authors.lastname: Oishi
authors.affiliation: a Departments of Neurology , Johns Hopkins University School of Medicine , Baltimore , MD , USA.
authors.forename: Rajani
authors.initials: R
authors.lastname: Sebastian
authors.affiliation: a Departments of Neurology , Johns Hopkins University School of Medicine , Baltimore , MD , USA.
authors.forename: Cornelia
authors.initials: C
authors.lastname: Demsky
authors.affiliation: b Departments of Neurosurgery , Johns Hopkins University School of Medicine , Baltimore , MD , USA.
authors.forename: Frederick
authors.initials: F
authors.lastname: Lenz
authors.affiliation: a Departments of Neurology , Johns Hopkins University School of Medicine , Baltimore , MD , USA.|e Departments of Physical Medicine & Rehabilitation , Johns Hopkins University School of Medicine , Baltimore , MD , USA.|f Department of Cognitive Science , Johns Hopkins University , Baltimore , MD , USA.
authors.forename: Argye E
authors.initials: AE
authors.lastname: Hillis
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001931:Brain Mapping; D016022:Case-Control Studies; D004644:Emotions / Q000502:physiology*; D005260:Female; D007839:Functional Laterality / Q000502:physiology; D005712:Galvanic Skin Response / Q000502:physiology; D066128:Gray Matter / Q000000981:diagnostic imaging; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D010468:Perceptual Disorders / Q000503:physiopathology; D018709:Statistics, Nonparametric; D020521:Stroke / Q000000981:diagnostic imaging / Q000503:physiopathology* / Q000523:psychology*; D066127:White Matter / Q000000981:diagnostic imaging; D055815:Young Adult
keywords: Empathy; autonomic nervous system; emotions; social cognition; stroke