title: Peripherin diverts ciliary ectosome release to photoreceptor disc morphogenesis.
abstract: Formation of membrane discs in photoreceptor cells requires evagination of its ciliary plasma membrane by an unknown molecular mechanism. Salinas et al. (2017.J. Cell Biol.https://doi.org/10.1083/jcb.201608081) show that peripherin (also known as peripherin-2 or peripherin-2/rds) diverts membrane traffic to photoreceptor disc formation by inhibiting ectosome release from the cilium.
authors.affiliation: Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, BC V6T 1Z3, Canada molday@mail.ubc.ca goldberg@oakland.edu.
authors.forename: Robert S
authors.identifier: 0000-0002-4479-1831
authors.initials: RS
authors.lastname: Molday
authors.affiliation: Eye Research Institute, Oakland University, Rochester, MI 48309 molday@mail.ubc.ca goldberg@oakland.edu.
authors.forename: Andrew F X
authors.identifier: 0000-0002-3964-5987
authors.initials: AFX
authors.lastname: Goldberg
mesh_terms: D055252:Cell-Derived Microparticles; D003598:Cytoskeletal Proteins; D007381:Intermediate Filament Proteins; D008562:Membrane Glycoproteins; D009024:Morphogenesis; D009419:Nerve Tissue Proteins; D064531:Peripherins; D010786:Photoreceptor Cells
chemical_list: D003598:Cytoskeletal Proteins; D007381:Intermediate Filament Proteins; D008562:Membrane Glycoproteins; D009419:Nerve Tissue Proteins; D064531:Peripherins