title: Double inversion recovery imaging of the brain: deriving the most relevant sequence through real images.
abstract: We propose a practical method for setting the optimal inversion times (TI) for double inversion recovery (DIR) sequences. Our method used the measurement of signal intensity (SI) from real images to set the optimal TI for white-matter (WM) and gray-matter (GM)-attenuated inversion recovery (WAIR and GAIR, respectively) images. 3D-DIR images of healthy volunteers were obtained on 1.5- and 3.0-T magnetic resonance (MR) scanners and the SIs of GM, WM, and cerebrospinal fluid (CSF) were evaluated on real images. We found TI2s at which the SI of WM or GM was null. Then, we found TI1+2(=TI1+ TI2) at which the SI of CSF was null. We defined the two TIs as optimal TIs. We assessed the utility of these TIs with additional volunteers and patients, and similar images were obtained with the determined TIs. Optimal TIs for DIR images could be efficiently determined using this method.
authors.affiliation: Department of Radiology, Josai Clinic, 2-13-23 Kokuryo-cho, Maebashi, Gunma, 371-0033, Japan. s_motegi_rt@yahoo.co.jp.|Department of Diagnostic Radiology and Nuclear Medicine, Gunma University Graduate School of Medicine, 3-39-22 Showa-machi, Maebashi, Gunma, 371-8511, Japan. s_motegi_rt@yahoo.co.jp.
authors.forename: Shunichi
authors.initials: S
authors.lastname: Motegi
authors.affiliation: Department of Diagnostic Radiology and Nuclear Medicine, Gunma University Graduate School of Medicine, 3-39-22 Showa-machi, Maebashi, Gunma, 371-8511, Japan.
authors.forename: Takehiro
authors.initials: T
authors.lastname: Shimada
authors.affiliation: School of Radiological Technology, Gunma Prefectural College of Health Sciences, 323-1 Kamioki-machi, Maebashi, Gunma, 371-0052, Japan.
authors.forename: Norio
authors.initials: N
authors.lastname: Hayashi
authors.affiliation: Department of Radiology, Maebashi Red Cross Hospital, 3-21-36 Asahi-cho, Maebashi, Gunma, 371-0014, Japan.
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Nagase
authors.affiliation: Department of Diagnostic Radiology and Nuclear Medicine, Gunma University Graduate School of Medicine, 3-39-22 Showa-machi, Maebashi, Gunma, 371-8511, Japan.
authors.forename: Ayako
authors.initials: A
authors.lastname: Taketomi-Takahashi
authors.affiliation: Department of Diagnostic Radiology and Nuclear Medicine, Gunma University Graduate School of Medicine, 3-39-22 Showa-machi, Maebashi, Gunma, 371-8511, Japan.
authors.forename: Yoshito
authors.initials: Y
authors.lastname: Tsushima
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001921:Brain / Q000000981:diagnostic imaging*; D002648:Child; D003116:Color; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D055815:Young Adult
keywords: Double inversion recovery; Gray-matter-attenuated inversion recovery (GAIR); Inversion recovery; Magnetic resonance imaging; White-matter-attenuated inversion recovery (WAIR)