title: Self-Assembled Carbon Dot Nanosphere: A Robust, Near-Infrared Light-Responsive, and Vein Injectable Photosensitizer.
abstract: Self-assembly "activated" carbon dot photosensitizer: a robust, NIR-light responsive, and vein injectable carbon dot nanosphere (CDNS) photosensitizer with1O2quantum yield of 0.45 under 671 nm laser irradiation has been developed through self-assembly using individual CD as building units. This study develops the biomedical applications of CD, highlights the self-assembly for designing well-defined CD-based photosensitizers, and promotes future explorations of this CDNS photosensitizer in nanomedical and clinical applications.
authors.affiliation: Key Laboratory of Photochemical Conversion and Optoelectronic Materials and CityU-CAS Joint Laboratory of Functional Materials and Devices, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing, 100190, P. R. China.|School of Future Technology, University of Chinese Academy of Sciences, Beijing, 100049, China.
authors.forename: Qingyan
authors.initials: Q
authors.lastname: Jia
authors.affiliation: Key Laboratory of Photochemical Conversion and Optoelectronic Materials and CityU-CAS Joint Laboratory of Functional Materials and Devices, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing, 100190, P. R. China.|School of Future Technology, University of Chinese Academy of Sciences, Beijing, 100049, China.
authors.forename: Jiechao
authors.initials: J
authors.lastname: Ge
authors.affiliation: Key Laboratory of Photochemical Conversion and Optoelectronic Materials and CityU-CAS Joint Laboratory of Functional Materials and Devices, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing, 100190, P. R. China.|School of Future Technology, University of Chinese Academy of Sciences, Beijing, 100049, China.
authors.forename: Weimin
authors.initials: W
authors.lastname: Liu
authors.affiliation: Key Laboratory of Photochemical Conversion and Optoelectronic Materials and CityU-CAS Joint Laboratory of Functional Materials and Devices, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing, 100190, P. R. China.|School of Future Technology, University of Chinese Academy of Sciences, Beijing, 100049, China.
authors.forename: Liang
authors.initials: L
authors.lastname: Guo
authors.affiliation: Key Laboratory of Photochemical Conversion and Optoelectronic Materials and CityU-CAS Joint Laboratory of Functional Materials and Devices, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing, 100190, P. R. China.|School of Future Technology, University of Chinese Academy of Sciences, Beijing, 100049, China.
authors.forename: Xiuli
authors.initials: X
authors.lastname: Zheng
authors.affiliation: Key Laboratory of Photochemical Conversion and Optoelectronic Materials and CityU-CAS Joint Laboratory of Functional Materials and Devices, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing, 100190, P. R. China.|School of Future Technology, University of Chinese Academy of Sciences, Beijing, 100049, China.
authors.forename: Shiqing
authors.initials: S
authors.lastname: Chen
authors.affiliation: Key Laboratory of Photochemical Conversion and Optoelectronic Materials and CityU-CAS Joint Laboratory of Functional Materials and Devices, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing, 100190, P. R. China.
authors.forename: Mingxing
authors.initials: M
authors.lastname: Chen
authors.affiliation: Key Laboratory of Photochemical Conversion and Optoelectronic Materials and CityU-CAS Joint Laboratory of Functional Materials and Devices, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing, 100190, P. R. China.
authors.forename: Sha
authors.initials: S
authors.lastname: Liu
authors.affiliation: Key Laboratory of Photochemical Conversion and Optoelectronic Materials and CityU-CAS Joint Laboratory of Functional Materials and Devices, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing, 100190, P. R. China.|School of Future Technology, University of Chinese Academy of Sciences, Beijing, 100049, China.
authors.forename: Liping
authors.initials: L
authors.lastname: Zhang
authors.affiliation: Key Laboratory of Photochemical Conversion and Optoelectronic Materials and CityU-CAS Joint Laboratory of Functional Materials and Devices, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing, 100190, P. R. China.
authors.forename: Mengqi
authors.initials: M
authors.lastname: Wang
authors.affiliation: Key Laboratory of Photochemical Conversion and Optoelectronic Materials and CityU-CAS Joint Laboratory of Functional Materials and Devices, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing, 100190, P. R. China.
authors.forename: Hongyan
authors.initials: H
authors.lastname: Zhang
authors.affiliation: Key Laboratory of Photochemical Conversion and Optoelectronic Materials and CityU-CAS Joint Laboratory of Functional Materials and Devices, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing, 100190, P. R. China.|School of Future Technology, University of Chinese Academy of Sciences, Beijing, 100049, China.
authors.forename: Pengfei
authors.initials: P
authors.lastname: Wang
mesh_terms: D000818:Animals; D001835:Body Weight; D002244:Carbon / Q000737:chemistry*; D045744:Cell Line, Tumor; D004578:Electron Spin Resonance Spectroscopy; D007259:Infrared Rays; D007267:Injections; D008819:Mice, Nude; D054118:Nanospheres / Q000737:chemistry* / Q000648:ultrastructure; D017319:Photosensitizing Agents / Q000008:administration & dosage / Q000494:pharmacology*; D013997:Time Factors; D014680:Veins / Q000187:drug effects*
chemical_list: D017319:Photosensitizing Agents; D002244:Carbon
keywords: carbon dot; fluorescent imaging; near-infrared light; photodynamic therapy; self-assembly