title: Preliminary Experience with Stent-Assisted Coiling of Aneurysms Arising from Small (<2.5 mm) Cerebral Vessels Using The Low-Profile Visualized Intraluminal Support Device.
abstract: OBJECTIVE
  The Low-Profile Visualized Intraluminal Support (LVIS) stent is a new device recently introduced for the treatment of wide-neck intracranial aneurysms. This single-center study presents the authors' preliminary experience using the LVIS stent to treat saccular aneurysms with parent arteries smaller than 2.5 mm.
  
  
  METHODS
  Aneurysms with a LVIS stent used in a small parent vessel (<2.5 mm in diameter) between October 2014 and April 2016 were included. Procedure-related complications, angiographic results, clinical outcomes, and midterm follow-up data were analyzed retrospectively.
  
  
  RESULTS
  A total of 22 patients was studied, including 5 ruptured and 17 unruptured aneurysms. Most of the aneurysms were located in the anterior circulation (90.9%). Stent placement in the parent arteries measuring 1.7-2.4 mm in diameter (mean, 2.1 mm) was successful in 100% of cases. Procedure-related complication developed in 1 patient (4.5%) who presented with aneurysm rupture. No permanent morbidity and mortality occurred. Immediate angiographic outcome showed complete occlusion in 8 aneurysms (36.4%), neck residual in 8 (36.4%), and residual aneurysm in 6 (27.3%). All patients underwent angiographic follow-up at a mean of 8.3 months, which revealed complete occlusion in 18 (81.8%) patients, neck remnant in 3 (13.6%), and residual sac in 1 (4.5%). No recanalization of the target aneurysm was observed. There was 1 case with asymptomatic in-stent stenosis.
  
  
  CONCLUSIONS
  Our preliminary results show that the deployment of LVIS stents in small vessels is feasible, safe, and effective in the midterm. Larger studies with long-term follow-up are needed to validate our promising results.
authors.affiliation: From the Department of Neurosurgery, Changhai Hospital, Second Military Medical University, Shanghai, China.
authors.forename: C-C
authors.identifier: http://orcid.org/0000-0002-9037-7439
authors.initials: CC
authors.lastname: Wang
authors.affiliation: From the Department of Neurosurgery, Changhai Hospital, Second Military Medical University, Shanghai, China.
authors.forename: W
authors.identifier: http://orcid.org/0000-0001-9187-6478
authors.initials: W
authors.lastname: Li
authors.affiliation: From the Department of Neurosurgery, Changhai Hospital, Second Military Medical University, Shanghai, China.
authors.forename: Z-Z
authors.identifier: http://orcid.org/0000-0002-4278-2202
authors.initials: ZZ
authors.lastname: Feng
authors.affiliation: From the Department of Neurosurgery, Changhai Hospital, Second Military Medical University, Shanghai, China.
authors.forename: B
authors.identifier: http://orcid.org/0000-0002-3508-9426
authors.initials: B
authors.lastname: Hong
authors.affiliation: From the Department of Neurosurgery, Changhai Hospital, Second Military Medical University, Shanghai, China.
authors.forename: Y
authors.identifier: http://orcid.org/0000-0001-5398-5411
authors.initials: Y
authors.lastname: Xu
authors.affiliation: From the Department of Neurosurgery, Changhai Hospital, Second Military Medical University, Shanghai, China. ocinhqh@163.com chstroke@163.com.
authors.forename: J-M
authors.identifier: http://orcid.org/0000-0002-3599-8267
authors.initials: JM
authors.lastname: Liu
authors.affiliation: From the Department of Neurosurgery, Changhai Hospital, Second Military Medical University, Shanghai, China. ocinhqh@163.com chstroke@163.com.
authors.forename: Q-H
authors.identifier: http://orcid.org/0000-0002-5612-5190
authors.initials: QH
authors.lastname: Huang
mesh_terms: D000328:Adult; D000368:Aged; D017542:Aneurysm, Ruptured / Q000628:therapy; D005260:Female; D006801:Humans; D002532:Intracranial Aneurysm / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D015607:Stents; D016896:Treatment Outcome