title: Microfracture: State of the Art in Cartilage Surgery?
abstract: Objective This study is a literature review from 2010 to 2014 concerning the quality of evidence in clinical trials about microfracture in attempt to repair articular cartilage. We have decided to focus on microfracturing, since this seems to be the best documented technique. Interest in evaluation of publication quality has risen in orthopaedic sports medicine recently. Therefore, we think it is necessary to evaluate recent clinical trials being rated for their evidence-based medicine (EBM) quality. We also compared the mean impact factor of the journals publishing the different studies as an indicator of the study's citation and evaluated for a change over the studied time frame. Design To measure the EBM level, we applied the modified Coleman Methodology Score (CMS) introduced by Jakobsen. The impact factor, which is a measurement of the yearly average number of citations of articles recently published in that journal, was evaluated according to self-reported values on the corresponding journal's website. Results We found that the mean CMS has not changed between 2010 and 2014. The mean impact factor has also not changed between 2010 and 2014. The CMS variance was high, pointing to different qualities in the evaluated studies. There is no evidence that microfracturing is superior compared to other cartilage repair procedures. Conclusion Microfracture cannot be seen as an evidence based procedure. Further research needs to be done and a standardization of the operating method is desirable. There need to be more substantial studies on microfracturing alone without additional therapies.
authors.affiliation: 1 University of Basel, Basel, Switzerland.
authors.forename: Florian
authors.initials: F
authors.lastname: Frehner
authors.affiliation: 1 University of Basel, Basel, Switzerland.
authors.forename: Jan P
authors.initials: JP
authors.lastname: Benthien
mesh_terms: D002358:Cartilage, Articular / Q000601:surgery*; D002986:Clinical Trials as Topic; D019317:Evidence-Based Medicine / Q000379:methods / Q000639:trends*; D015775:Fractures, Stress / Q000601:surgery*; D006801:Humans; D019637:Orthopedic Procedures / Q000379:methods / Q000639:trends*
keywords: cartilage; evidence-based medicine (EBM); microfracture; surgery