title: A topological look at human trabecular bone tissue.
abstract: Bone quality is affected by trabecular architecture at microscopic level. Various abnormalities of bone tissue lead to altered strength and to an increased susceptibility to fracture, such as Osteoporosis and Osteoarthritis, two major health burdens of our society. These are two complex musculoskeletal diseases that mainly concern bone tissue. In the last twenty years, there has been a growing interest in finding an appropriate topological model for the micro-architecture of trabecular bone tissue. In particular, we prove that these models involve general topological spaces. The appropriate notion to deal with is that of CW-complex.
authors.affiliation: Department of Mathematics "F. Enriques", Via C. Saldini, 50 - 20133 Milan, Italy. Electronic address: gilberto.bini@unimi.it.
authors.forename: G
authors.initials: G
authors.lastname: Bini
authors.affiliation: Department of Mechanical and Aerospace Engineering, 'Sapienza' University of Rome, Via Eudossiana 18 - 00184 Rome, Italy. Electronic address: fabiano.bini@uniroma1.it.
authors.forename: F
authors.initials: F
authors.lastname: Bini
authors.affiliation: ISS- Department of Technology and Health, V.le Regina Elena, 299 - 00161 Rome, Italy. Electronic address: rossella.bedini@iss.it.
authors.forename: R
authors.initials: R
authors.lastname: Bedini
authors.affiliation: Orthopedy and Traumatology Area,'Campus Bio-Medico' University, Via Alvaro del Portillo, 200 - 00128 Rome, Italy. Electronic address: a.marinozzi@unicampus.it.
authors.forename: A
authors.initials: A
authors.lastname: Marinozzi
authors.affiliation: Department of Mechanical and Aerospace Engineering, 'Sapienza' University of Rome, Via Eudossiana 18 - 00184 Rome, Italy. Electronic address: franco.marinozzi@uniroma1.it.
authors.forename: F
authors.initials: F
authors.lastname: Marinozzi
mesh_terms: D015519:Bone Density; D000071556:Cancellous Bone / Q000033:anatomy & histology* / Q000166:cytology / Q000502:physiology; D006801:Humans
keywords: CW-complex; Euler characteristic; Kelvin cell; Trabecular bone tissue