title: Squaramide-Sulfonamide Organocatalyst for Asymmetric Direct Vinylogous Aldol Reactions.
abstract: Asymmetric direct vinylogous aldol reactions of furan-2(5H)-one with aldehydes in the presence of a catalytic amount of novel squaramide-sulfonamide organocatalyst resulted in the corresponding addition products with high to excellent enantioselectivities. This is the first successful report illustrating an example of highly stereoselective reactions using a squaramide-sulfonamide organocatalyst.
authors.affiliation: Tokyo University of Pharmacy , Life Sciences, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan.
authors.forename: Takaaki
authors.initials: T
authors.lastname: Sakai
authors.affiliation: Tokyo University of Pharmacy , Life Sciences, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan.
authors.forename: Shin-Ichi
authors.initials: SI
authors.lastname: Hirashima
authors.affiliation: Tokyo University of Pharmacy , Life Sciences, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan.
authors.forename: Yoshifumi
authors.initials: Y
authors.lastname: Yamashita
authors.affiliation: Tokyo University of Pharmacy , Life Sciences, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan.
authors.forename: Ryoga
authors.initials: R
authors.lastname: Arai
authors.affiliation: Tokyo University of Pharmacy , Life Sciences, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan.
authors.forename: Kosuke
authors.initials: K
authors.lastname: Nakashima
authors.affiliation: Tokyo University of Pharmacy , Life Sciences, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan.
authors.forename: Akihiro
authors.initials: A
authors.lastname: Yoshida
authors.affiliation: Tokyo University of Pharmacy , Life Sciences, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan.
authors.forename: Yuji
authors.initials: Y
authors.lastname: Koseki
authors.affiliation: Tokyo University of Pharmacy , Life Sciences, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan.
authors.forename: Tsuyoshi
authors.identifier: 0000-0003-1216-4507
authors.initials: T
authors.lastname: Miura