title: Extranodal NK/T Cell Lymphoma with Destruction of the Uvulae: A Case Report.
abstract: BACKGROUND
  Extranodal Natural Killer (NK)/T-cell lymphoma (NKTCL) nasal type is a rare but well-known disease with poor prognosis. NKTCL is more prevalent in Asia and comprises about 7-10% of all non-Hodgkin lymphoma cases in this region. The characteristic clinical pattern of NKTCL is the destruction of the midline structures of the mid-face.
  
  
  METHODS
  The present study examines a case of NKTCL in a 23-year-old man with a destructive ulcer of the palate and uvulae. Based on immunohistochemical results, after three months of delay, the definitive diagnosis was revealed to be Extranodal NK/T cell lymphoma. Following the third cycle of chemotherapy, the patient died due to sepsis and infection.
  
  
  CONCLUSIONS
  It is very common to misdiagnose NKTCL with other clinical conditions such as necrotizing stomatitis, deep fungal ulcers, Wegener's Granulomatosis disease, etc. Delay in diagnosis can worsen the course of the disease and its prognosis.
authors.affiliation: Allergy Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
authors.forename: Farahzad
authors.initials: F
authors.lastname: Jabbari Azad
authors.affiliation: Oral and Maxillofacial Diseases Research Center, Faculty of Dentistry, Mashhad University of Medical Science, Mashhad, Iran.
authors.forename: Zahra
authors.initials: Z
authors.lastname: Delavarian
authors.affiliation: Department of Oral and Maxillofacial Medicine, Faculty of Dentistry, Mashhad University of Medical Science, Mashhad, Iran.
authors.forename: Masoud
authors.initials: M
authors.lastname: Hatami
authors.affiliation: Department of Hematology-Oncology, Mashhad University of Medical Science, Mashhad, Iran.
authors.forename: Hosein
authors.initials: H
authors.lastname: Rahimi
authors.affiliation: Allergy Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
authors.forename: Mohammad Reza
authors.initials: MR
authors.lastname: Abdolvahed
keywords: Extranodal NK-T-cell lymphoma; Oral ucer; Palate; Uvula