title: Pneumocytoma (sclerosing hemangioma), a potential pitfall.
abstract: Pneumocytoma is an uncommon benign tumor of the lung, derived from primitive respiratory epithelium, with a predilection for middle-aged females. A single, well-circumscribed mass is commonly identified on imaging, necessitating pathologic evaluation for further assessment. Fine-needle aspiration cytology is a minimally invasive and cost-effective method that can be utilized in the diagnosis of these lesions. Yet, distinction of pneumocytoma from other entities such as well-differentiated adenocarcinoma or carcinoid tumor can be quite challenging. Herein, we describe a case initially misdiagnosed as lung adenocarcinoma on FNA that was proven to be pneumocytoma on subsequent resection. This report highlights the importance of recognizing key cytologic features of pneumocytoma, namely the papillary architecture, dual cell population, and the hemorrhagic background with foamy macrophages, among others. An accurate preoperative diagnosis of this entity provides optimal patient management, as conservative surgical excision is curative. Diagn. Cytopathol. 2017;45:744-749. © 2017 Wiley Periodicals, Inc.
authors.affiliation: Department of Pathology & Laboratory Medicine, Papanicolaou Cytology Laboratory, New York-Presbyterian Hospital, Weill Cornell Medical College, New York.
authors.forename: Erika
authors.identifier: http://orcid.org/0000-0002-2606-6812
authors.initials: E
authors.lastname: Hissong
authors.affiliation: Department of Pathology & Laboratory Medicine, Papanicolaou Cytology Laboratory, New York-Presbyterian Hospital, Weill Cornell Medical College, New York.
authors.forename: Rema
authors.initials: R
authors.lastname: Rao
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis; D000077192:Adenocarcinoma of Lung; D044963:Biopsy, Fine-Needle; D003951:Diagnostic Errors; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis; D008875:Middle Aged; D047868:Pulmonary Sclerosing Hemangioma / Q000175:diagnosis*
keywords: fine-needle aspiration cytology; sclerosing hemangioma of lung; sclerosing pneumocytoma