title: Self-Assembly Can Direct Dynamic Covalent Bond Formation toward Diversity or Specificity.
abstract: With the advent of reversible covalent chemistry the study of the interplay between covalent bond formation and noncovalent interactions has become increasingly relevant. Here we report that the interplay between reversible disulfide chemistry and self-assembly can give rise either to molecular diversity, i.e., the emergence of a unprecedentedly large range of macrocycles or to molecular specificity, i.e., the autocatalytic emergence of a single species. The two phenomena are the result of two different modes of self-assembly, demonstrating that control over self-assembly pathways can enable control over covalent bond formation.
authors.affiliation: Centre for Systems Chemistry, Stratingh Institute, University of Groningen , Nijenborgh 4, 9747 AG Groningen, The Netherlands.
authors.forename: Dávid
authors.initials: D
authors.lastname: Komáromy
authors.affiliation: Centre for Systems Chemistry, Stratingh Institute, University of Groningen , Nijenborgh 4, 9747 AG Groningen, The Netherlands.
authors.forename: Marc C A
authors.initials: MCA
authors.lastname: Stuart
authors.affiliation: Centre for Systems Chemistry, Stratingh Institute, University of Groningen , Nijenborgh 4, 9747 AG Groningen, The Netherlands.
authors.forename: Guillermo
authors.initials: G
authors.lastname: Monreal Santiago
authors.affiliation: Centre for Systems Chemistry, Stratingh Institute, University of Groningen , Nijenborgh 4, 9747 AG Groningen, The Netherlands.
authors.forename: Meniz
authors.initials: M
authors.lastname: Tezcan
authors.affiliation: Zernike Institute for Advanced Materials, University of Groningen , Nijenborgh 4, 9747 AG Groningen, The Netherlands.
authors.forename: Victor V
authors.initials: VV
authors.lastname: Krasnikov
authors.affiliation: Centre for Systems Chemistry, Stratingh Institute, University of Groningen , Nijenborgh 4, 9747 AG Groningen, The Netherlands.
authors.forename: Sijbren
authors.identifier: 0000-0003-0259-5637
authors.initials: S
authors.lastname: Otto