title: Factors associated with pregnancy-related knowledge in women of reproductive age with inflammatory bowel disease.
abstract: OBJECTIVE
  Inflammatory bowel disease (IBD) usually develops at a young age, and many women experience marriage, pregnancy, and delivery during the disease course. We aimed to evaluate the pregnancy-related knowledge of women with IBD in Korea and investigate the associated factors.
  
  
  METHODS
  A total of 270 women with IBD, aged 19-45 years, from four tertiary hospitals in Korea were administered a questionnaire comprising 17 questions from the validated Crohn's and Colitis Pregnancy Knowledge Score (CCPKnow) that were translated into Korean.
  
  
  RESULTS
  The average CCPKnow score of the 270 patients was 7.47 ± 3.07; and most of the patients (51.5%) exhibited a poor knowledge level. Younger age at diagnosis, Crohn's disease rather than ulcerative colitis, longer disease duration, anti-TNF-α medication history, higher household income, and delivery after diagnosis were associated with an appropriate level of pregnancy-related knowledge. Younger age at diagnosis (odds ratio [OR], 1.87; p = .036), anti-TNF-α therapy (OR, 1.87; p = .047), and delivery while suffering from IBD (OR, 3.07; p = .002) were independent factors affecting the pregnancy-related knowledge level. Approximately 69.6% of patients acquired related knowledge from their gastroenterology doctor, whereas 19.4% of patients intended to remain childless.
  
  
  CONCLUSIONS
  To our knowledge, this is the first study to assess the pregnancy-related knowledge of women of reproductive-age with IBD and their perceptions by using a questionnaire in Asia. As more than half of the patients showed a poor knowledge level of IBD, a general education program should be conducted by gastroenterology doctors.
authors.affiliation: a Department of Internal Medicine , Ewha Womans University School of Medicine , Seoul , Republic of Korea.
authors.forename: Ko Eun
authors.initials: KE
authors.lastname: Lee
authors.affiliation: a Department of Internal Medicine , Ewha Womans University School of Medicine , Seoul , Republic of Korea.
authors.forename: Sung-Ae
authors.initials: SA
authors.lastname: Jung
authors.affiliation: b Department of Internal Medicine , Seoul National University Bundang Hospital , Seongnam , Gyeonggi-do , Republic of Korea.
authors.forename: Hyuk
authors.initials: H
authors.lastname: Yoon
authors.affiliation: c Department of Gastroenterology , University of Ulsan College of Medicine , Seoul , Republic of Korea.
authors.forename: Sang Hyoung
authors.initials: SH
authors.lastname: Park
authors.affiliation: a Department of Internal Medicine , Ewha Womans University School of Medicine , Seoul , Republic of Korea.
authors.forename: Chang Mo
authors.initials: CM
authors.lastname: Moon
authors.affiliation: d Department of Internal Medicine , Kyungpook National University School of Medicine , Daegu , Republic of Korea.|e Department of Internal Medicine , Keimyung University School of Medicine , Daegu , Republic of Korea.
authors.forename: Eun Soo
authors.initials: ES
authors.lastname: Kim
authors.affiliation: a Department of Internal Medicine , Ewha Womans University School of Medicine , Seoul , Republic of Korea.
authors.forename: Seong-Eun
authors.initials: SE
authors.lastname: Kim
authors.affiliation: c Department of Gastroenterology , University of Ulsan College of Medicine , Seoul , Republic of Korea.
authors.forename: Suk-Kyun
authors.initials: SK
authors.lastname: Yang
mesh_terms: D000328:Adult; D003430:Cross-Sectional Studies; D005260:Female; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D015212:Inflammatory Bowel Diseases / Q000188:drug therapy / Q000503:physiopathology*; D016015:Logistic Models; D008875:Middle Aged; D011247:Pregnancy; D011248:Pregnancy Complications / Q000503:physiopathology*; D011446:Prospective Studies; D056910:Republic of Korea; D011795:Surveys and Questionnaires; D062606:Tertiary Care Centers; D014409:Tumor Necrosis Factor-alpha / Q000037:antagonists & inhibitors; D055815:Young Adult
chemical_list: D014409:Tumor Necrosis Factor-alpha
keywords: Inflammatory bowel disease; knowledge; pregnancy; women