title: NEK2 induces osteoclast differentiation and bone destruction via heparanase in multiple myeloma.
authors.affiliation: State Key Laboratory of Experimental Hematology, Institute of Hematology &Blood Diseases Hospital, Chinese Academy of Medical Science &Peking Union Medical College, Tianjin, China.|Division of Hematology, Oncology, and Blood and Marrow Transplantation, Department of Internal Medicine, University of Iowa, Iowa City, IA, USA.
authors.forename: M
authors.initials: M
authors.lastname: Hao
authors.affiliation: Division of Hematology, Oncology, and Blood and Marrow Transplantation, Department of Internal Medicine, University of Iowa, Iowa City, IA, USA.|Molecular &Cellular Biology Program, University of Iowa, Iowa City, IA, USA.
authors.forename: R
authors.initials: R
authors.lastname: Franqui-Machin
authors.affiliation: Division of Hematology, Oncology, and Blood and Marrow Transplantation, Department of Internal Medicine, University of Iowa, Iowa City, IA, USA.
authors.forename: H
authors.initials: H
authors.lastname: Xu
authors.affiliation: Department of Medicine, Mount Sinai School of Medicine, New York, NY, USA.
authors.forename: J
authors.initials: J
authors.lastname: Shaughnessy
authors.affiliation: Department of Medicine, Mount Sinai School of Medicine, New York, NY, USA.
authors.forename: B
authors.initials: B
authors.lastname: Barlogie
authors.affiliation: Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA.
authors.forename: D
authors.initials: D
authors.lastname: Roodman
authors.affiliation: Department of Pharmacology, University of Iowa, Iowa City, IA, USA.
authors.forename: D E
authors.initials: DE
authors.lastname: Quelle
authors.affiliation: Department of Pathology, The University of Iowa Roy J and Lucille A Carver College of Medicine, Iowa City, IA, USA.
authors.forename: S
authors.initials: S
authors.lastname: Janz
authors.affiliation: Division of Hematology, Oncology, and Blood and Marrow Transplantation, Department of Internal Medicine, University of Iowa, Iowa City, IA, USA.
authors.forename: M H
authors.initials: MH
authors.lastname: Tomasson
authors.affiliation: Department of Pathology, University of Alabama at Birmingham, Birmingham, AL, USA.
authors.forename: R D
authors.initials: RD
authors.lastname: Sanderson
authors.affiliation: State Key Laboratory of Experimental Hematology, Institute of Hematology &Blood Diseases Hospital, Chinese Academy of Medical Science &Peking Union Medical College, Tianjin, China.
authors.forename: L
authors.initials: L
authors.lastname: Qiu
authors.affiliation: Division of Hematology, Oncology, and Blood and Marrow Transplantation, Department of Internal Medicine, University of Iowa, Iowa City, IA, USA.
authors.forename: I
authors.initials: I
authors.lastname: Frech
authors.affiliation: Division of Hematology, Oncology, and Blood and Marrow Transplantation, Department of Internal Medicine, University of Iowa, Iowa City, IA, USA.
authors.forename: G
authors.initials: G
authors.lastname: Tricot
authors.affiliation: Division of Hematology, Oncology, and Blood and Marrow Transplantation, Department of Internal Medicine, University of Iowa, Iowa City, IA, USA.|Molecular &Cellular Biology Program, University of Iowa, Iowa City, IA, USA.
authors.forename: F
authors.initials: F
authors.lastname: Zhan
mesh_terms: D001842:Bone and Bones / Q000378:metabolism*; D002454:Cell Differentiation / Q000502:physiology*; D005966:Glucuronidase / Q000378:metabolism*; D006801:Humans; D009101:Multiple Myeloma / Q000378:metabolism* / Q000473:pathology; D000072379:NIMA-Related Kinases / Q000378:metabolism* / Q000502:physiology; D010010:Osteoclasts / Q000473:pathology*; D000099175:Heparanase
chemical_list: D005966:Glucuronidase; D000072379:NIMA-Related Kinases; D000099175:Heparanase; C089441:NEK2 protein, human