title: Antibacterial Action of Jineol Isolated fromScolopendra subspinipes mutilansagainst Selected Foodborne Pathogens.
abstract: This study was undertaken to assess the antibacterial potential of 3,8-dihydroxyquinoline (jineol) isolated fromScolopendra subspinipes mutilansagainst selected foodborne pathogensEscherichia coliO157:H7 andStaphylococcus aureusKCTC-1621. Jineol at the tested concentration (50 μL; corresponding to 250 μg/disk) exhibited significant antibacterial effects as a diameter of inhibition zones (11.6-13.6 mm), along with minimum inhibitory concentration (MIC) and minimum bactericidal concentration values found in the range of (62.5-125 μg/mL) and (125-250 μg/mL), respectively. Jineol also exhibited significant antibacterial effects as confirmed by the reduction in bacterial cell viabilities, increasing release of potassium (K+) ions (650 and 700 mmole/L) and 260 nm materials (optical density: 2.98-3.12) against both the tested pathogens,E. coliO157:H7 andS. aureusKCTC-1621, respectively. Moreover, changes in the cell wall morphology ofE. coliO157:H7 andS. aureusKCTC-1621 cells treated with jineol at MIC further confirmed its inhibitory potential against the tested pathogens, suggesting its role as an effective antimicrobial to control foodborne pathogens.
authors.affiliation: Microbiome Laboratory, Department of Applied Microbiology and Biotechnology, Yeungnam University Gyeongsan, South Korea.
authors.forename: Vivek K
authors.initials: VK
authors.lastname: Bajpai
authors.affiliation: Department of Energy and Materials Engineering, Dongguk University Seoul, South Korea.
authors.forename: Shruti
authors.initials: S
authors.lastname: Shukla
authors.affiliation: National Science Museum, Ministry of Science, ICT and Future Planning Daejeon, South Korea.
authors.forename: Woon K
authors.initials: WK
authors.lastname: Paek
authors.affiliation: National Science Museum, Ministry of Science, ICT and Future Planning Daejeon, South Korea.
authors.forename: Jeongheui
authors.initials: J
authors.lastname: Lim
authors.affiliation: Department of Forestry, North Eastern Regional Institute of Science and Technology (Deemed University) Nirjuli, India.
authors.forename: Pradeep
authors.initials: P
authors.lastname: Kumar
authors.affiliation: College of Pharmacy, Chungnam National University Daejeon, South Korea.
authors.forename: MinKyun
authors.initials: M
authors.lastname: Na
keywords: antimicrobial effect; foodbrone pathogens; jineol; scanning electron microscopy