title: Anterior segment migration of dexamethasone implant: risk factors, complications, and management.
abstract: OBJECTIVE
  To describe the risk factors, clinical course, and complications related to anterior segment migration of a dexamethasone (DEX) intravitreal implant, and review over potential management strategies.
  
  
  RESULTS
  Recent reports have demonstrated that migration of a DEX implant into the anterior chamber may occur in patients with higher risk ocular characteristics. Although a relatively rare occurrence, DEX implant migration carries the possibility of inducing potentially vision-threatening corneal endothelial decompensation and edema.
  
  
  CONCLUSIONS
  Any combination of previous pars plana vitrectomy, an open/defective lens capsule, and/or iris defects may increase the risk of DEX implant migration into the anterior chamber. In the setting of a DEX implant that has moved into the anterior segment with corneal edema already present, urgent removal of the implant is warranted to reduce the risk of permanent visual compromise.
authors.affiliation: aDepartment of Ophthalmology, Palo Alto Medical Foundation, Palo AltobNorthern California Retina Vitreous Associates, Mountain ViewcDepartment of Ophthalmology, University of California, San Francisco, California, USA.
authors.forename: Ehsan
authors.initials: E
authors.lastname: Rahimy
authors.forename: Rahul N
authors.initials: RN
authors.lastname: Khurana
mesh_terms: D000869:Anterior Eye Segment / Q000473:pathology*; D020878:Device Removal; D003907:Dexamethasone / Q000008:administration & dosage*; D004343:Drug Implants / Q000009:adverse effects*; D005548:Foreign-Body Migration / Q000209:etiology* / Q000601:surgery; D005938:Glucocorticoids / Q000008:administration & dosage*; D006801:Humans; D012307:Risk Factors; D014821:Vitrectomy
chemical_list: D004343:Drug Implants; D005938:Glucocorticoids; D003907:Dexamethasone