title: A new polyketide glycoside from the rhizospheric Clonostachys rogersoniana associated with Panax notoginseng.
abstract: A new polyketide glycoside rogerson A (1), along with two known compounds, rogerson B (2) and (22E)-5α,8α-epidioxyergosta-6,22-dien-3β-ol (3), was obtained from the solid fermentation of Clonostachys rogersoniana, which was isolated from the rhizosphere soil of Panax notoginseng. Rogerson B (2) was isolated for the first time from a natural source. Their structure was determined by extensive analyses of NMR and MS studies. Compounds 1 and 2 were tested for its cytotoxicity against five human cancer cell lines.
authors.affiliation: a School of Chemical Science and Technology , Yunnan University , Kunming 650091 , China.|b Zhuhai Key Laboratory of Fundamental and Applied Research in Traditional Chinese Medicine , Zunyi Medical University Zhuhai Campus , Zhuhai 519041 , China.
authors.forename: Tian-Peng
authors.initials: TP
authors.lastname: Yin
authors.affiliation: a School of Chemical Science and Technology , Yunnan University , Kunming 650091 , China.
authors.forename: Yun
authors.initials: Y
authors.lastname: Xing
authors.affiliation: a School of Chemical Science and Technology , Yunnan University , Kunming 650091 , China.
authors.forename: Le
authors.initials: L
authors.lastname: Cai
authors.affiliation: a School of Chemical Science and Technology , Yunnan University , Kunming 650091 , China.
authors.forename: Jing
authors.initials: J
authors.lastname: Yu
authors.affiliation: a School of Chemical Science and Technology , Yunnan University , Kunming 650091 , China.
authors.forename: Ping
authors.initials: P
authors.lastname: Luo
authors.affiliation: a School of Chemical Science and Technology , Yunnan University , Kunming 650091 , China.
authors.forename: Zhong-Tao
authors.initials: ZT
authors.lastname: Ding
mesh_terms: D004875:Ergosterol / Q000031:analogs & derivatives / Q000737:chemistry; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification*; D006999:Hypocreales / Q000737:chemistry*; D015394:Molecular Structure; D053723:Panax notoginseng / Q000737:chemistry*; D061065:Polyketides / Q000737:chemistry / Q000302:isolation & purification*; D058441:Rhizosphere
chemical_list: C503471:5alpha,8alpha-epidioxyergosta-6,22-dien-3-beta-ol; D006027:Glycosides; D061065:Polyketides; C000625251:rogerson A; D004875:Ergosterol
keywords: Clonostachys rogersoniana; Panax notoginseng; cytotoxicity; polyketide glycoside; rogerson