title: [Topical haemostatic agents in neurosurgery].
abstract: Haemostasis is of fundamental significance in neurosurgery, and insufficient control of bleeding is associated with morbidity and mortality. Topical haemostatic agents play an important role, as the characteristics of neuronal tissue limit the use of classical surgical haemostasis techniques. Appropriate choice of agent depends on the location and type of bleeding, but also on knowledge of the products' mechanisms of action, indications, price and accessibility. Biological products are superior to the mechanical in efficacy but require more preparation and are significantly more cost-intensive.
authors.affiliation: jon.foss-skiftesvik@regionh.dk.
authors.forename: Jon
authors.initials: J
authors.lastname: Foss-Skiftesvik
authors.forename: Rachid
authors.initials: R
authors.lastname: Bech-Azeddine
mesh_terms: D016063:Blood Loss, Surgical / Q000517:prevention & control; D002483:Cellulose, Oxidized / Q000008:administration & dosage / Q000191:economics / Q000627:therapeutic use; D003094:Collagen / Q000008:administration & dosage / Q000191:economics / Q000627:therapeutic use; D005337:Fibrin / Q000008:administration & dosage / Q000191:economics / Q000627:therapeutic use; D006487:Hemostasis / Q000187:drug effects / Q000502:physiology; D006490:Hemostatics / Q000008:administration & dosage / Q000191:economics / Q000493:pharmacokinetics / Q000627:therapeutic use; D006801:Humans; D006861:Hydrogen Peroxide / Q000008:administration & dosage / Q000191:economics / Q000627:therapeutic use; D019635:Neurosurgical Procedures / Q000191:economics / Q000379:methods*; D010168:Palmitates / Q000008:administration & dosage / Q000191:economics / Q000627:therapeutic use; D012965:Sodium Chloride / Q000008:administration & dosage / Q000191:economics / Q000627:therapeutic use; D015503:Surgical Sponges / Q000191:economics; D013917:Thrombin / Q000008:administration & dosage / Q000191:economics / Q000627:therapeutic use; D014885:Waxes / Q000191:economics / Q000627:therapeutic use
chemical_list: D002483:Cellulose, Oxidized; D006490:Hemostatics; D010168:Palmitates; D014885:Waxes; D012965:Sodium Chloride; C055480:bone wax; D005337:Fibrin; D003094:Collagen; D006861:Hydrogen Peroxide; D013917:Thrombin