title: A gas scintillator detector for 2D dose profile monitoring in pencil beam scanning and pulsed beam proton radiotherapy treatments.
abstract: In order to address dosimetry demands during proton therapy treatments utilizing pencil beam scanning and/or pulsed beam accelerators, we have developed a xenon-filled gas scintillation detector (GSD) that can monitor delivered dose and 2D beam centroid position pulse-by-pulse in real time, with high response linearity up to high instantaneous dose rates. We present design considerations for the GSD and results of beam tests carried out at operating proton therapy clinics. In addition to demonstrating spatial resolution with σ of a few hundred microns in each transverse dimension and relative dose precision better than 1% over large treatment areas, the test beam results also reveal the dependence of the GSD dose normalization on dose rate, beam energy, and gas impurities. The results demonstrate the promise of the GSD technology to provide an important addition to dosimetry approaches for next-generation ion beam therapy.
authors.affiliation: Phenix Medical LLC, Bloomington, IN 47404, United States of America.
authors.forename: S E
authors.initials: SE
authors.lastname: Vigdor
authors.forename: A V
authors.initials: AV
authors.lastname: Klyachko
authors.forename: K A
authors.initials: KA
authors.lastname: Solberg
authors.forename: M
authors.initials: M
authors.lastname: Pankuch
mesh_terms: D006801:Humans; D061766:Proton Therapy; D011829:Radiation Dosage; D011877:Radionuclide Imaging; D011879:Radiotherapy Dosage; D012588:Scintillation Counting / Q000295:instrumentation*; D014978:Xenon
chemical_list: D014978:Xenon