title: High transition frequencies of dynamic functional connectivity states in the creative brain.
abstract: Creativity is thought to require the flexible reconfiguration of multiple brain regions that interact in transient and complex communication patterns. In contrast to prior emphases on searching for specific regions or networks associated with creative performance, we focused on exploring the association between the reconfiguration of dynamic functional connectivity states and creative ability. We hypothesized that a high frequency of dynamic functional connectivity state transitions will be associated with creative ability. To test this hypothesis, we recruited a high-creative group (HCG) and a low-creative group (LCG) of participants and collected resting-state fMRI (R-fMRI) data and Torrance Tests of Creative Thinking (TTCT) scores from each participant. By combining an independent component analysis with a dynamic network analysis approach, we discovered the HCG had more frequent transitions between dynamic functional connectivity (dFC) states than the LCG. Moreover, a confirmatory analysis using multiplication of temporal derivatives also indicated that there were more frequent dFC state transitions in the HCG. Taken together, these results provided empirical evidence for a linkage between the flexible reconfiguration of dynamic functional connectivity states and creative ability. These findings have the potential to provide new insights into the neural basis of creativity.
authors.affiliation: Center for the Study of Applied Psychology, Key Laboratory of Mental Health and Cognitive Science of Guangdong Province, School of Psychology, South China Normal University, Guangzhou, China.
authors.forename: Junchao
authors.initials: J
authors.lastname: Li
authors.affiliation: Center for the Study of Applied Psychology, Key Laboratory of Mental Health and Cognitive Science of Guangdong Province, School of Psychology, South China Normal University, Guangzhou, China.
authors.forename: Delong
authors.initials: D
authors.lastname: Zhang
authors.affiliation: Guangdong Science Center, Guangzhou, China.
authors.forename: Aiying
authors.initials: A
authors.lastname: Liang
authors.affiliation: College of Education, Guangdong Polytechnic Normal University, Guangzhou, China.
authors.forename: Bishan
authors.initials: B
authors.lastname: Liang
authors.affiliation: Center for the Study of Applied Psychology, Key Laboratory of Mental Health and Cognitive Science of Guangdong Province, School of Psychology, South China Normal University, Guangzhou, China.
authors.forename: Zengjian
authors.initials: Z
authors.lastname: Wang
authors.affiliation: Center for the Study of Applied Psychology, Key Laboratory of Mental Health and Cognitive Science of Guangdong Province, School of Psychology, South China Normal University, Guangzhou, China.
authors.forename: Yuxuan
authors.initials: Y
authors.lastname: Cai
authors.affiliation: Center for the Study of Applied Psychology, Key Laboratory of Mental Health and Cognitive Science of Guangdong Province, School of Psychology, South China Normal University, Guangzhou, China.
authors.forename: Mengxia
authors.initials: M
authors.lastname: Gao
authors.affiliation: Center for the Study of Applied Psychology, Key Laboratory of Mental Health and Cognitive Science of Guangdong Province, School of Psychology, South China Normal University, Guangzhou, China.
authors.forename: Zhenni
authors.initials: Z
authors.lastname: Gao
authors.affiliation: Center for the Study of Applied Psychology, Key Laboratory of Mental Health and Cognitive Science of Guangdong Province, School of Psychology, South China Normal University, Guangzhou, China.
authors.forename: Song
authors.initials: S
authors.lastname: Chang
authors.affiliation: Center for the Study of Applied Psychology, Key Laboratory of Mental Health and Cognitive Science of Guangdong Province, School of Psychology, South China Normal University, Guangzhou, China.
authors.forename: Bingqing
authors.initials: B
authors.lastname: Jiao
authors.affiliation: Center for the Study of Applied Psychology, Key Laboratory of Mental Health and Cognitive Science of Guangdong Province, School of Psychology, South China Normal University, Guangzhou, China.
authors.forename: Ruiwang
authors.initials: R
authors.lastname: Huang
authors.affiliation: Center for the Study of Applied Psychology, Key Laboratory of Mental Health and Cognitive Science of Guangdong Province, School of Psychology, South China Normal University, Guangzhou, China.
authors.forename: Ming
authors.initials: M
authors.lastname: Liu
mesh_terms: D000293:Adolescent; D001921:Brain / Q000502:physiology*; D003405:Creativity; D005260:Female; D006801:Humans; D007361:Intelligence Tests; D008279:Magnetic Resonance Imaging; D008297:Male; D009434:Neural Pathways / Q000502:physiology*; D013997:Time Factors