title: Incidence and factors associated with mortality in 2,476 patients with variant angina in Korea.
abstract: This study investigated the incidence and risk factors of mortality in 2,476 patients with variant angina (VA) using the National Health Insurance Service-National Sample Cohort between 2004 and 2011. The risk factors of all-cause and cardiac mortality were investigated using Cox proportional hazards model. Most patients (69.5%) were less than 65 years and 42.9% were women. During the median follow-up duration of 4.9 years, there were 178 (7.2%) and 95 (3.8%) cases of all-cause and cardiac mortality, respectively. Older age, hypertension, diabetes mellitus, poor medication adherence, low household income and tertiary teaching hospitals were independent predictors for all-cause mortality, while older age, hypertension, low household income and tertiary teaching hospitals were independent predictors for cardiac mortality. In conclusion, our findings suggest that traditional risk factor control and continued medication are important to improve VA outcomes, and that household income-level factors should be considered in the assessment of risk of VA patients.
authors.affiliation: Division of Cardiology, Department of Internal Medicine, Boramae Medical Center, Seoul, Korea.|Seoul National University College of Medicine, Seoul, Korea.
authors.forename: Hack-Lyoung
authors.initials: HL
authors.lastname: Kim
authors.affiliation: Institute of Health and Environment, Seoul National University, Seoul, Korea.
authors.forename: Jayeun
authors.initials: J
authors.lastname: Kim
authors.affiliation: Department of Nursing Science, Shinsung University, Dangjin, Korea.
authors.forename: Hyun Joo
authors.initials: HJ
authors.lastname: Kim
authors.affiliation: Division of Cardiology, Department of Internal Medicine, Boramae Medical Center, Seoul, Korea.|Seoul National University College of Medicine, Seoul, Korea.
authors.forename: Woo-Hyun
authors.initials: WH
authors.lastname: Lim
authors.affiliation: Seoul National University College of Medicine, Seoul, Korea.|Public Health Medical Service, Boramae Medical Center, Seoul, Korea.|Institute of Health Policy and Management, Medical Research Center, Seoul National University, Seoul, Korea.
authors.forename: Jin Yong
authors.initials: JY
authors.lastname: Lee
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000788:Angina Pectoris, Variant / Q000401:mortality*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D008297:Male; D055118:Medication Adherence; D008875:Middle Aged; D056910:Republic of Korea / Q000453:epidemiology; D012307:Risk Factors; D016019:Survival Analysis; D055815:Young Adult