title: Genome Architecture from a Different Angle.
abstract: The study of genome architecture has recently been advanced by new techniques combining nuclear proximity ligation and high-throughput sequencing, but independent methods to validate them have been lacking. Reporting in Nature, Beagrie et al. (2017) describe such an orthogonal technique, called genome architecture mapping, to map genomes in 3D space.
authors.affiliation: National Cancer Institute, NIH, Bethesda, MD 20892, USA.
authors.forename: Elizabeth H
authors.initials: EH
authors.lastname: Finn
authors.affiliation: National Cancer Institute, NIH, Bethesda, MD 20892, USA. Electronic address: mistelit@mail.nih.gov.
authors.forename: Tom
authors.initials: T
authors.lastname: Misteli
mesh_terms: D002874:Chromosome Mapping; D016678:Genome; D059014:High-Throughput Nucleotide Sequencing