title: A Novel Independent Survival Predictor in Pulmonary Embolism: Prognostic Nutritional Index.
abstract: The prognostic impact of nutritional status in patients with pulmonary embolism (PE) is poorly understood. A well-accepted nutritional status parameter, prognostic nutritional index (PNI), which was first demonstrated to be valuable in patients with cancer and gastrointestinal surgery, was introduced to patients with PE. Our aim was to evaluate the predictive value of PNI in outcomes of patients with PE. We evaluated the in-hospital and long-term (53.8 ± 5.4 months) prognostic impact of PNI on 251 patients with PE. During a median follow-up of 53.8 ± 5.4 months, 27 (11.6%) patients died in hospital course and 31 (13.4%) died in out-of-hospital course. The patients with lower PNI had significantly higher in-hospital and long-term mortality. The Cox proportional hazard analyses showed that PNI was associated with an increased risk of all-cause death for both unadjusted model and adjusted for all covariates. Our study demonstrated that PNI, calculated based on serum albumin level and lymphocyte count, is an independent prognostic factor for mortality in patients with PE.
authors.affiliation: 1 Department of Cardiology, Dr Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital, Istanbul, Turkey.
authors.forename: Mert İlker
authors.initials: Mİ
authors.lastname: Hayıroğlu
authors.affiliation: 1 Department of Cardiology, Dr Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital, Istanbul, Turkey.
authors.forename: Muhammed
authors.initials: M
authors.lastname: Keskin
authors.affiliation: 2 Department of Allergy/Immunology, Albert Einstein College of Medicine and Montefiore Medical Center, Yeshiva University, Bronx, NY, USA.
authors.forename: Taha
authors.initials: T
authors.lastname: Keskin
authors.affiliation: 1 Department of Cardiology, Dr Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital, Istanbul, Turkey.
authors.forename: Ahmet Okan
authors.initials: AO
authors.lastname: Uzun
authors.affiliation: 3 Department of Cardiology, Trakya University, Edirne, Turkey.
authors.forename: Servet
authors.initials: S
authors.lastname: Altay
authors.affiliation: 4 Department of Cardiology, Düzce University Faculty of Medicine, Düzce, Turkey.
authors.forename: Adnan
authors.initials: A
authors.lastname: Kaya
authors.affiliation: 1 Department of Cardiology, Dr Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital, Istanbul, Turkey.
authors.forename: Ahmet
authors.initials: A
authors.lastname: Öz
authors.affiliation: 1 Department of Cardiology, Dr Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital, Istanbul, Turkey.
authors.forename: Göksel
authors.initials: G
authors.lastname: Çinier
authors.affiliation: 1 Department of Cardiology, Dr Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital, Istanbul, Turkey.
authors.forename: Tolga Sinan
authors.initials: TS
authors.lastname: Güvenç
authors.affiliation: 1 Department of Cardiology, Dr Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital, Istanbul, Turkey.
authors.forename: Ömer
authors.initials: Ö
authors.lastname: Kozan
mesh_terms: D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009752:Nutritional Status / Q000235:genetics*; D010865:Pilot Projects; D011379:Prognosis; D011655:Pulmonary Embolism / Q000401:mortality* / Q000473:pathology
keywords: mortality; prognostic nutritional index; pulmonary embolism