title: Paraneoplastic Neurological Disorder in Nasopharyngeal Carcinoma.
abstract: Paraneoplastic neurological disorder (PND) is a condition due to immune cross-reactivity between the tumour cells and the normal tissue, whereby the "onconeural" antibodies attack the normal host nervous system. It can present within weeks to months before or after the diagnosis of malignancies. Nasopharyngeal carcinoma is associated with paraneoplastic syndrome, for example, dermatomyositis, and rarely with a neurological disorder. We report on a case of nasopharyngeal carcinoma with probable PND. Otolaryngologists, oncologists and neurologists need to be aware of this condition in order to make an accurate diagnosis and to provide prompt treatment.
authors.affiliation: Department of Otorhinolaryngology, Head & Neck Surgery, UKM Medical Centre, Jalan Yaacob Latif, 56000 Cheras, Kuala Lumpur, Malaysia.
authors.forename: Sze Yin
authors.initials: SY
authors.lastname: Ng
authors.affiliation: Department of Otorhinolaryngology, Head & Neck Surgery, UKM Medical Centre, Jalan Yaacob Latif, 56000 Cheras, Kuala Lumpur, Malaysia.
authors.forename: Min Han
authors.initials: MH
authors.lastname: Kongg
authors.affiliation: Department of Otorhinolaryngology, Head & Neck Surgery, UKM Medical Centre, Jalan Yaacob Latif, 56000 Cheras, Kuala Lumpur, Malaysia.
authors.forename: Mohd Razif Mohamad
authors.initials: MR
authors.lastname: Yunus
keywords: PND; nasopharyngeal carcinoma; nervous system; neurological disorder; paraneoplastic polyneuropathy; paraneoplastic syndrome