title: Comparative effectiveness of single versus multiple tablet antiretroviral therapy regimens in clinical HIV practice.
abstract: We determined risk of virologic failure (VF) in individuals initiating tenofovir/emtricitabine/efavirenz as single versus multiple tablet regimens (MTR). We found no significant difference in the risk of VF, though did observe a trend toward more VF and M184 V mutations among persons initiating MTR. Temporal trends in care may have confounded results.
authors.affiliation: Division of Allergy and Infectious Diseases, University of Washington, Seattle, WA Division of Infectious Diseases Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL Department of Medicine, University of California San Diego, San Diego Gilead Sciences, Foster City, CA Fenway Health Center, Harvard Medical School, Boston, MA Department of Epidemiology, University of North Carolina, Chapel Hill, NC Bristol-Myers Squibb, Princeton, NJ.
authors.forename: Daniel R
authors.initials: DR
authors.lastname: Drozd
authors.forename: Michael S
authors.initials: MS
authors.lastname: Saag
authors.forename: Andrew O
authors.initials: AO
authors.lastname: Westfall
authors.forename: William Chris
authors.initials: WC
authors.lastname: Mathews
authors.forename: Richard
authors.initials: R
authors.lastname: Haubrich
authors.forename: Stephen L
authors.initials: SL
authors.lastname: Boswell
authors.forename: Stephen R
authors.initials: SR
authors.lastname: Cole
authors.forename: Donna
authors.initials: D
authors.lastname: Porter
authors.forename: Mari M
authors.initials: MM
authors.lastname: Kitahata
authors.forename: Timothy
authors.initials: T
authors.lastname: Juday
authors.forename: Lisa
authors.initials: L
authors.lastname: Rosenblatt
mesh_terms: D000328:Adult; D044966:Anti-Retroviral Agents / Q000008:administration & dosage*; D005260:Female; D015658:HIV Infections / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome
chemical_list: D044966:Anti-Retroviral Agents