title: Evaluation of accuracy and precision of CT-guidance in Radiofrequency Ablation for osteoid osteoma in 86 patients.
abstract: OBJECTIVE
  Osteoid osteoma is a benign skeletal tumour that accounts for 2-3% of all bone tumours. The male-to-female ratio is around 4:1 and it predominates in children and young adults. The most common symptom is pain, frequently at night-time. Historically the main form of treatment has been surgical excision. With the development of Radiofrequency Ablation (RFA) there is a percutaneus alternative. Success rates of RFA are lower but the main advantage is the minimal invasive character of the therapy and the low complication rate. As a result of the minimal invasiveness the hospitalization- and rehabilitation periods are relatively short. However, in current literature no values for accuracy and precision are known for the CT-guided positioning.
  
  
  METHODS
  Accuracy and precision of the needle position are determined for 86 procedures. Furthermore the population is divided into groups based on tumour diameter, location and procedure outcome.
  
  
  RESULTS
  The clinical success rate was 81.4%. In 79% of procedures complete ablation was achieved. Accuracy was 2.84 mm on average, precision was 2.94 mm. Accuracy was significantly lower in more profound lesions. Accuracy in tibia and fibula was significantly higher compared to the femur. No significant difference was found between different tumour diameters.
  
  
  CONCLUSIONS
  The accuracy and precision found are considered good. Needle position is of major importance for procedure outcomes. The question however rises how the results of this therapy will turn out in treatment of larger tumours.
authors.affiliation: Department of Orthopaedics, University of Groningen, University Medical Center Groningen, Groningen, Netherlands.
authors.forename: H
authors.identifier: http://orcid.org/0000-0002-0130-2452
authors.initials: H
authors.lastname: Nijland
authors.affiliation: Department of Orthopaedics, University of Groningen, University Medical Center Groningen, Groningen, Netherlands.
authors.forename: J G
authors.initials: JG
authors.lastname: Gerbers
authors.affiliation: Department of Orthopaedics, University of Groningen, University Medical Center Groningen, Groningen, Netherlands.
authors.forename: S K
authors.initials: SK
authors.lastname: Bulstra
authors.affiliation: Department of Radiology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands.
authors.forename: J
authors.initials: J
authors.lastname: Overbosch
authors.affiliation: Department of Orthopaedics, University of Groningen, University Medical Center Groningen, Groningen, Netherlands.
authors.forename: M
authors.initials: M
authors.lastname: Stevens
authors.affiliation: Department of Orthopaedics, University of Groningen, University Medical Center Groningen, Groningen, Netherlands.
authors.forename: P C
authors.initials: PC
authors.lastname: Jutte
mesh_terms: D000293:Adolescent; D000328:Adult; D017115:Catheter Ablation / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D010017:Osteoma, Osteoid / Q000601:surgery*; D015203:Reproducibility of Results; D014057:Tomography, X-Ray Computed / Q000379:methods*; D055815:Young Adult