title: Predictive prognostic value of neutrophil-lymphocytes ratio in acute coronary syndrome.
abstract: OBJECTIVE
  To assess the relationship between neutrophil-lymphocytes ratio (NLR) at admission and patient outcome over a period of six month in subjects with acute coronary syndrome (ACS).
  
  
  METHODS
  A total of 435 consecutive patients presenting with ACS were enrolled and 400 patients completed the study. Patients were categorized into 2 groups: the NLR group 1 (NLR≤5.25; n=265, 66.25%) and the NLR group 2 (NLR>5.25; n=135, 33.75%). The primary outcomes were in-hospital and 6 months mortality.
  
  
  RESULTS
  Forty-seven (11.8%) patients died during 6 months follow up. Higher mortality was seen in NLR group 2 (42/135, 34.1%) compared to NLR group 1 (5/265, 1.9%) with p value <0.001.
  
  
  CONCLUSIONS
  Our study suggest that elevated NLR (>5.25) is independently associated with higher all-cause mortality rate up to 6 months period irrespective of ACS type.
authors.affiliation: S.N. Medical College, Jodhpur 342011, India. Electronic address: rajesh.bajari@gmail.com.
authors.forename: Rajesh
authors.initials: R
authors.lastname: Bajari
authors.affiliation: S.N. Medical College, Jodhpur 342011, India. Electronic address: drstak@yahoo.com.
authors.forename: Sandeep
authors.initials: S
authors.lastname: Tak
mesh_terms: D054058:Acute Coronary Syndrome / Q000097:blood* / Q000175:diagnosis / Q000401:mortality; D002423:Cause of Death / Q000639:trends; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007194:India / Q000453:epidemiology; D007958:Leukocyte Count; D008214:Lymphocytes / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009504:Neutrophils / Q000473:pathology*; D010343:Patient Admission; D011379:Prognosis; D012307:Risk Factors; D015996:Survival Rate / Q000639:trends; D013997:Time Factors
keywords: Acute coronary syndrome (ACS); Mortality; Neutrophil–lymphocytes ratio (NLR)