title: Transition-metal-catalyzed synthesis of phenols and aryl thiols.
abstract: Phenols and aryl thiols are fundamental building blocks in organic synthesis and final products with interesting biological activities. Over the past decades, substantial progress has been made in transition-metal-catalyzed coupling reactions, which resulted in the emergence of new methods for the synthesis of phenols and aryl thiols. Aryl halides have been extensively studied as substrates for the synthesis of phenols and aryl thiols. In very recent years, C-H activation represents a powerful strategy for the construction of functionalized phenols directly from various arenes. However, the synthesis of aryl thiols through C-H activation has not been reported. In this review, a brief overview is given of the recent advances in synthetic strategies for both phenols and aryl thiols.
authors.affiliation: College of Life Science and Medicine, Dalian University of Technology, Panjin 124221, China.
authors.forename: Yajun
authors.initials: Y
authors.lastname: Liu
authors.affiliation: College of Life Science and Medicine, Dalian University of Technology, Panjin 124221, China.
authors.forename: Shasha
authors.initials: S
authors.lastname: Liu
authors.affiliation: Department of Pharmaceutical Engineering, Shenyang Pharmaceutical University, Shenyang 110016, China.
authors.forename: Yan
authors.initials: Y
authors.lastname: Xiao
keywords: C–O bond; C–S bond; aryl thiol; phenol; transition metal