title: SpecificblaCTX-M-8/IncI1 Plasmid Transfer among Genetically Diverse Escherichia coli Isolates between Humans and Chickens.
abstract: We investigated the genetic backbones of 14blaCTX-M-8-positiveEscherichia coliisolates recovered from human stool samples and chicken meat. All isolates carried IncI1 plasmids withblaCTX-M-8(blaCTX-M-8/IncI1), and most (9/14) belonged to a specific genetic lineage, namely, plasmid sequence type 113 (pST113). The genetic contexts of the nineblaCTX-M-8/IncI1 pST113 plasmids were similar, regardless of the source. These results suggest the probable local transfer ofblaCTX-M-8/IncI1 between humans and chickens with genetically diverseE. coli.
authors.affiliation: Department of Pathophysiological Laboratory Sciences, Nagoya University Graduate School of Medicine, Nagoya, Japan.
authors.forename: Chihiro
authors.initials: C
authors.lastname: Norizuki
authors.affiliation: Department of Bacteriology, Nagoya University Graduate School of Medicine, Nagoya, Japan wachino@med.nagoya-u.ac.jp.
authors.forename: Jun-Ichi
authors.initials: JI
authors.lastname: Wachino
authors.affiliation: Laboratory of Bacteriology, Aichi Prefecture Institute of Public Health, Nagoya, Japan.
authors.forename: Masahiro
authors.initials: M
authors.lastname: Suzuki
authors.affiliation: Department of Pathophysiological Laboratory Sciences, Nagoya University Graduate School of Medicine, Nagoya, Japan.
authors.forename: Kumiko
authors.initials: K
authors.lastname: Kawamura
authors.affiliation: Department of Health and Medical Sciences, Shinshu University Graduate School of Medicine, Matsumoto, Japan.
authors.forename: Noriyuki
authors.initials: N
authors.lastname: Nagano
authors.affiliation: Department of Bacteriology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
authors.forename: Kouji
authors.initials: K
authors.lastname: Kimura
authors.affiliation: Department of Bacteriology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
authors.forename: Yoshichika
authors.initials: Y
authors.lastname: Arakawa
mesh_terms: D000818:Animals; D002645:Chickens; D004926:Escherichia coli / Q000187:drug effects / Q000235:genetics*; D029968:Escherichia coli Proteins / Q000235:genetics; D014644:Genetic Variation / Q000235:genetics; D006801:Humans; D008460:Meat / Q000382:microbiology; D010957:Plasmids / Q000235:genetics*; D001618:beta-Lactamases / Q000235:genetics
chemical_list: D029968:Escherichia coli Proteins; D001618:beta-Lactamases
keywords: Escherichia coli; IncI1 plasmid; blaCTX-M-8; human; retail chicken meat