title: An overview application of silver nanoparticles in inhibition of herpes simplex virus.
abstract: Nanoscale particles and molecules are a potential different for the treatment of disease because they have distinctive biologic property based on their structure and size, which is different from traditional small-molecule drugs. The antimicrobial mechanisms of silver nanoparticles include the formation of free radicals damaging the bacterial membranes, interactions with DNA, adhesion to cell surface altering the membrane properties, and enzyme damage. In this review, we focus on applications of silver nanoparticles in inhibition of herpes simplex virus.
authors.affiliation: a Stem Cell Research Center , Tabriz University of Medical Sciences , Tabriz , Iran.|b Joint Ukraine-Azerbaijan International Research and Education Center of Nanobiotechnology and Functional Nanosystems , Drohobych , Ukraine & Baku , Azerbaijan.|c Universal Scientific Education and Research Network (USERN) , Tabriz , Iran.
authors.forename: Abolfazl
authors.initials: A
authors.lastname: Akbarzadeh
authors.affiliation: d Student Research Committee , Tabriz Azad University , Tabriz , Iran.|e Drug Applied Research Center , Tabriz University of Medical Sciences , Tabriz , Iran.
authors.forename: Leila
authors.initials: L
authors.lastname: Kafshdooz
authors.affiliation: e Drug Applied Research Center , Tabriz University of Medical Sciences , Tabriz , Iran.
authors.forename: Zohre
authors.initials: Z
authors.lastname: Razban
authors.affiliation: e Drug Applied Research Center , Tabriz University of Medical Sciences , Tabriz , Iran.
authors.forename: Ali
authors.initials: A
authors.lastname: Dastranj Tbrizi
authors.affiliation: f Department of Chemistry , Isfahan University of Technology , Isfahan , Islamic Republic of Iran.
authors.forename: Shadi
authors.initials: S
authors.lastname: Rasoulpour
authors.affiliation: b Joint Ukraine-Azerbaijan International Research and Education Center of Nanobiotechnology and Functional Nanosystems , Drohobych , Ukraine & Baku , Azerbaijan.|g Institute of Radiation Problems , National Academy of Sciences of Azerbaijan , Baku , Azerbaijan.|h Faculty of Biology, Department of Biophysics and Molecular Biology , Baku State University , Baku , Azerbaijan Republic.
authors.forename: Rovshan
authors.initials: R
authors.lastname: Khalilov
authors.affiliation: b Joint Ukraine-Azerbaijan International Research and Education Center of Nanobiotechnology and Functional Nanosystems , Drohobych , Ukraine & Baku , Azerbaijan.|i The John Paul II Catholic University of Lublin , Lublin , Poland.
authors.forename: Taras
authors.initials: T
authors.lastname: Kavetskyy
authors.affiliation: b Joint Ukraine-Azerbaijan International Research and Education Center of Nanobiotechnology and Functional Nanosystems , Drohobych , Ukraine & Baku , Azerbaijan.|h Faculty of Biology, Department of Biophysics and Molecular Biology , Baku State University , Baku , Azerbaijan Republic.
authors.forename: Siamak
authors.initials: S
authors.lastname: Saghfi
authors.affiliation: b Joint Ukraine-Azerbaijan International Research and Education Center of Nanobiotechnology and Functional Nanosystems , Drohobych , Ukraine & Baku , Azerbaijan.|g Institute of Radiation Problems , National Academy of Sciences of Azerbaijan , Baku , Azerbaijan.
authors.forename: Aygun N
authors.initials: AN
authors.lastname: Nasibova
authors.affiliation: j Department of Basic Science , Farhangian University , Tehran , Iran.
authors.forename: Sharif
authors.initials: S
authors.lastname: Kaamyabi
authors.affiliation: k Biotechnology Research Center, Tabriz University of Medical Sciences , Tabriz , Iran.
authors.forename: Taiebeh
authors.initials: T
authors.lastname: Kafshdooz
mesh_terms: D000998:Antiviral Agents / Q000737:chemistry* / Q000494:pharmacology*; D006561:Herpes Simplex / Q000453:epidemiology / Q000209:etiology; D006801:Humans; D053768:Metal Nanoparticles; D012834:Silver / Q000737:chemistry* / Q000494:pharmacology*; D018139:Simplexvirus / Q000187:drug effects* / Q000502:physiology
chemical_list: D000998:Antiviral Agents; D012834:Silver
keywords: Antimicrobial activity; herpes simplex virus; nanomaterials; silver nanoparticles