title: A two-photon fluorescent probe for specific detection of hydrogen sulfide based on a familiar ESIPT fluorophore bearing AIE characteristics.
abstract: Hydrogen sulfide (H2S) is a signaling gasotransmitter, which plays various roles in modulating the functions of different systems. In this study, a "turn-on" fluorescent probe for H2S was developed. The probe, whose design is based on a familiar excited state intramolecular proton transfer (ESIPT) fluorophore bearing aggregation-induced emission (AIE) characteristics, was found to exhibit an 80-fold fluorescence enhancement along with a large Stokes shift upon the addition of H2S. Furthermore, the probe was successfully utilized to detect H2S in HeLa cells with both one-photon and two-photon microscopy.
authors.affiliation: Department of Chemistry and Nano Science, Ewha Womans University, Seoul, 120-750, Korea. jyoon@ewha.ac.kr wudi19871208@163.com.
authors.forename: Liyan
authors.initials: L
authors.lastname: Chen
authors.forename: Di
authors.initials: D
authors.lastname: Wu
authors.forename: Chang Su
authors.initials: CS
authors.lastname: Lim
authors.forename: Dayoung
authors.initials: D
authors.lastname: Kim
authors.forename: Sang-Jip
authors.initials: SJ
authors.lastname: Nam
authors.forename: Woolin
authors.initials: W
authors.lastname: Lee
authors.forename: Gyungmi
authors.initials: G
authors.lastname: Kim
authors.forename: Hwan Myung
authors.initials: HM
authors.lastname: Kim
authors.forename: Juyoung
authors.initials: J
authors.lastname: Yoon