title: Next Generation Sequencing and Multi-Gene Panel Testing: Implications for the Oncology Nurse.
abstract: To review past, current, and future events in genetics and discuss how genetic testing information personalizes cancer screening, detection, and treatment. A case study is presented to illustrate key points.
  
  
  
  National guidelines, evidence-based summaries, peer-reviewed studies, editorials, and web sites.
  
  
  
  Multi-gene testing using next-generation sequencing has changed the landscape for hereditary cancer syndromes.
  
  
  
  Nurses have key roles in personalizing health care including recognizing the complexities of genetic testing, assessing family history, understanding gene/environment factors, referring for genetics consultations, and promoting registry studies. In order to be effective, nurses must stay current with the rapidly-changing technology and guidelines for genetic evaluations and testing.
authors.forename: Patricia A
authors.initials: PA
authors.lastname: Kelly
mesh_terms: D000328:Adult; D002983:Clinical Competence; D005260:Female; D020022:Genetic Predisposition to Disease; D006801:Humans; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000175:diagnosis* / Q000235:genetics* / Q000451:nursing; D009720:Nurse Clinicians / Q000592:standards*; D009859:Oncology Nursing / Q000592:standards*
keywords: ATM gene; genetic testing; hereditary breast cancer; multi-gene panels; next-generation sequencing; personalized health care