title: Lipoprotein-X disease in the setting of severe cholestatic hepatobiliary autoimmune disease.
abstract: Severe cholestatic disease and hyperlipidemia are both commonly encountered by medical professionals. This article reviews the current pathophysiological model of lipoprotein-X syndrome related to 3 cases from 2 academic medical centers in the United States.
authors.affiliation: Department of Medicine, Emory University, Atlanta, GA, USA.
authors.forename: Robert E
authors.initials: RE
authors.lastname: Heinl
authors.affiliation: Department of Clinical Pharmacology, University of Kansas Medical Center, Kansas City, KS, USA.
authors.forename: Heather M
authors.initials: HM
authors.lastname: Tennant
authors.affiliation: Department of Medicine, Emory University, Atlanta, GA, USA.
authors.forename: John C
authors.initials: JC
authors.lastname: Ricketts
authors.affiliation: Division of Cardiology, Department of Medicine, Emory University, Atlanta, GA, USA.
authors.forename: Claire R
authors.initials: CR
authors.lastname: Rice
authors.affiliation: Division of Cardiology, Department of Medicine, Emory University, Atlanta, GA, USA.
authors.forename: Cordelia B
authors.initials: CB
authors.lastname: Robinson
authors.affiliation: Department of Medicine, Emory University, Atlanta, GA, USA; Division of Cardiology, Department of Medicine, Emory University, Atlanta, GA, USA.
authors.forename: Pratik B
authors.initials: PB
authors.lastname: Sandesara
authors.affiliation: Department of Clinical Pharmacology, University of Kansas Medical Center, Kansas City, KS, USA.
authors.forename: Patrick M
authors.initials: PM
authors.lastname: Moriarty
authors.affiliation: Department of Medicine, Emory University, Atlanta, GA, USA; Division of Cardiology, Department of Medicine, Emory University, Atlanta, GA, USA. Electronic address: lsperli@emory.edu.
authors.forename: Laurence
authors.initials: L
authors.lastname: Sperling
mesh_terms: D000328:Adult; D001327:Autoimmune Diseases / Q000150:complications*; D002779:Cholestasis / Q000150:complications* / Q000378:metabolism*; D005260:Female; D006801:Humans; D008073:Lipoprotein-X / Q000378:metabolism*; D008107:Liver Diseases / Q000150:complications*; D008297:Male; D008875:Middle Aged
chemical_list: D008073:Lipoprotein-X
keywords: Apheresis; Cholestatic liver disease; Hyperlipidemia; Lipoprotein; Lipoprotein-X disease; Liver transplantation