title: Short Communication: Resolution of Tenofovir Disoproxil Fumarate Induced Fanconi Syndrome with Switch to Tenofovir Alafenamide Fumarate in a HIV-1 and Hepatitis B Coinfected Patient.
abstract: Fanconi syndrome is a rare adverse effect of tenofovir disoproxil fumarate (TDF). Tenofovir alafenamide fumarate (TAF) is a novel prodrug with less nephrotoxicity. We report resolution of Fanconi syndrome in a HIV and hepatitis B coinfected patient switched from TDF to TAF.
authors.affiliation: Department of Medicine, University of California San Diego , San Diego, California.
authors.forename: Maile Young
authors.initials: MY
authors.lastname: Karris
mesh_terms: D000225:Adenine / Q000008:administration & dosage / Q000031:analogs & derivatives*; D000409:Alanine; D019380:Anti-HIV Agents / Q000008:administration & dosage* / Q000009:adverse effects*; D060085:Coinfection / Q000150:complications / Q000188:drug therapy; D005198:Fanconi Syndrome / Q000139:chemically induced*; D015658:HIV Infections / Q000150:complications* / Q000188:drug therapy; D019694:Hepatitis B, Chronic / Q000150:complications*; D006801:Humans; D008297:Male; D008875:Middle Aged; D000068698:Tenofovir / Q000008:administration & dosage / Q000009:adverse effects* / Q000031:analogs & derivatives; D016896:Treatment Outcome
chemical_list: D019380:Anti-HIV Agents; D000068698:Tenofovir; C442442:tenofovir alafenamide; D000225:Adenine; D000409:Alanine
keywords: Fanconi syndrome; HIV; hepatitis B; tenofovir alafenamide