title: Effect of bio-electrochemical system on the fate and proliferation of chloramphenicol resistance genes during the treatment of chloramphenicol wastewater.
abstract: Bioelectrochemical systems can effectively degrade antibiotics, but there is the need to better understand the fate of antibiotic resistance bacteria and antibiotic resistance genes during the bioelectrochemical degradation of antibiotics. In this study, a BES was developed as a platform to investigate the fate of chloramphenicol resistance bacteria (CRB) and the expression of chloramphenicol resistance genes (CRGs) under different operating conditions during chloramphenicol biodegradation. The results indicated that chloramphenicol was effectively removed and chloramphenicol removal efficiency could be improved under less chloramphenicol concentration and more negative cathode potential. Higher chloramphenicol concentration enhanced the enrichment of CRB and expression of CRGs. Furthermore, the abundances of CRB were enhanced under more negative cathode potential, the expression of CRGs under less negative cathode potential were induced. However, both the enrichment of CRB and expression of CRGs could be moderated under a medium cathode potential. This result could provide the scientific reference for research about the fate of antibiotic resistance genes in bioelectrochemical systems.
authors.affiliation: Shandong Key Laboratory of Water Pollution Control and Resource Reuse, School of Environmental Science and Engineering, Shandong University, Jinan 250100, China.
authors.forename: Ning
authors.initials: N
authors.lastname: Guo
authors.affiliation: Shandong Key Laboratory of Water Pollution Control and Resource Reuse, School of Environmental Science and Engineering, Shandong University, Jinan 250100, China. Electronic address: ykwang@sdu.edu.cn.
authors.forename: Yunkun
authors.initials: Y
authors.lastname: Wang
authors.affiliation: State Key Laboratory of Microbial Technology, School of Life Sciences, Shandong University, Jinan 250100, China.
authors.forename: Lei
authors.initials: L
authors.lastname: Yan
authors.affiliation: Shandong Key Laboratory of Water Pollution Control and Resource Reuse, School of Environmental Science and Engineering, Shandong University, Jinan 250100, China.
authors.forename: Xinhua
authors.initials: X
authors.lastname: Wang
authors.affiliation: State Key Laboratory of Microbial Technology, School of Life Sciences, Shandong University, Jinan 250100, China.
authors.forename: Mingyu
authors.initials: M
authors.lastname: Wang
authors.affiliation: State Key Laboratory of Microbial Technology, School of Life Sciences, Shandong University, Jinan 250100, China.
authors.forename: Hai
authors.initials: H
authors.lastname: Xu
authors.affiliation: Shandong Key Laboratory of Water Pollution Control and Resource Reuse, School of Environmental Science and Engineering, Shandong University, Jinan 250100, China. Electronic address: wsg@sdu.edu.cn.
authors.forename: Shuguang
authors.initials: S
authors.lastname: Wang
mesh_terms: D002701:Chloramphenicol; D002702:Chloramphenicol Resistance; D055664:Electrochemical Techniques; D004566:Electrodes; D062065:Wastewater
chemical_list: D002701:Chloramphenicol; D062065:Wastewater
keywords: Antibiotic resistance bacteria; Antibiotic resistance genes; Bioelectrochemical system; Chloramphenicol; Relative expression