title: TTK Chitra tilting disc heart valve model TC2: An assessment of fatigue life and durability.
abstract: Average age group of heart valve replacement in India and most of the Third World countries is below 30 years. Hence, the valve for such patients need to be designed to have a service life of 50 years or more which corresponds to 2000 million cycles of operation. The purpose of this study was to assess the structural performance of the TTK Chitra tilting disc heart valve model TC2 and thereby address its durability. The TC2 model tilting disc heart valves were assessed to evaluate the risks connected with potential structural failure modes. To be more specific, the studies covered the finite element analysis-based fatigue life prediction and accelerated durability testing of the tilting disc heart valves for nine different valve sizes. First, finite element analysis-based fatigue life prediction showed that all nine valve sizes were in the infinite life region. Second, accelerated durability test showed that all nine valve sizes remained functional for 400 million cycles under experimental conditions. The study ensures the continued function of TC2 model tilting disc heart valves over duration in excess of 50 years. The results imply that the TC2 model valve designs are structurally safe, reliable and durable.
authors.affiliation: Department of Medical Devices Engineering, Biomedical Technology Wing, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, India.
authors.forename: N N
authors.initials: NN
authors.lastname: Subhash
authors.affiliation: Department of Medical Devices Engineering, Biomedical Technology Wing, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, India.
authors.forename: Adathala
authors.initials: A
authors.lastname: Rajeev
authors.affiliation: Department of Medical Devices Engineering, Biomedical Technology Wing, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, India.
authors.forename: Sreedharan
authors.initials: S
authors.lastname: Sujesh
authors.affiliation: Department of Medical Devices Engineering, Biomedical Technology Wing, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, India.
authors.forename: C V
authors.initials: CV
authors.lastname: Muraleedharan
mesh_terms: D020342:Finite Element Analysis; D006350:Heart Valve Prosthesis; D011474:Prosthesis Design; D011475:Prosthesis Failure; D013997:Time Factors
keywords: Heart valve; accelerated durability test; high-risk implants