title: Development of Supramolecular Saccharide Sensors Based on Cyclodextrin Complexes and Self-assembling Systems.
abstract: Cyclodextrins (CDs) are water-soluble host compounds having nano-size hydrophobic cavities that enable them to incorporate organic molecules in water. Optically inert CDs can be efficiently combined with various types of chromoionophores and fluoroionophores. In this study, using diverse combinations of phenylboronic acid fluorescent sensors and azoprobes with CDs, the unique saccharide recognition functions of CD, chemically modified CD, and CD gel complexes based on their synergistic function are clarified, thereby confirming their use as supramolecular saccharide sensors. To realize novel supramolecular chirality, the twisted structure of two ditopic azoprobes inside the γ-CD chiral cavity is controlled by multi-point recognition of guest ions in water. As different types of supramolecular saccharide sensors, phenylboronic acid-based self-assembling systems are also reviewed.
authors.affiliation: Department of Materials and Life Sciences, Faculty of Science and Technology, Sophia University.
authors.forename: Yuji
authors.initials: Y
authors.lastname: Tsuchido
authors.forename: Shoji
authors.initials: S
authors.lastname: Fujiwara
authors.forename: Takeshi
authors.initials: T
authors.lastname: Hashimoto
authors.forename: Takashi
authors.initials: T
authors.lastname: Hayashita
mesh_terms: D001391:Azo Compounds / Q000737:chemistry*; D001897:Boronic Acids / Q000737:chemistry*; D002241:Carbohydrates / Q000032:analysis*; D003505:Cyclodextrins / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000138:chemical synthesis / Q000737:chemistry*; D057927:Hydrophobic and Hydrophilic Interactions; D046911:Macromolecular Substances / Q000138:chemical synthesis / Q000737:chemistry; D010316:Particle Size; D013499:Surface Properties
chemical_list: D001391:Azo Compounds; D001897:Boronic Acids; D002241:Carbohydrates; D003505:Cyclodextrins; D005456:Fluorescent Dyes; D046911:Macromolecular Substances; C010686:benzeneboronic acid