title: Consistency of Renal Stone Volume Measurements Across CT Scanner Model and Reconstruction Algorithm Configurations.
abstract: OBJECTIVE
  The objective of this prospective study is to evaluate the consistency of renal stone volume estimation using dual-energy CT across scanner model and reconstruction algorithm configurations.
  
  
  METHODS
  Patients underwent scanning with routine kidney stone composition protocols on both second- and third-generation dual-source CT scanners. Images were reconstructed using filtered back projection and iterative reconstruction (IR). In addition, a modified IR kernel on the third-generation CT scanner was evaluated. Individual kidney stone volumes were determined and compared.
  
  
  RESULTS
  No significant difference was noted in measured volumes between filtered back-projection data, IR data from the second-generation scanner, and the modified IR kernel data (p > 0.05). The third-generation commercially available IR kernel yielded lower volumes than did the other configurations (p < 0.0001).
  
  
  CONCLUSIONS
  With the use of a modified kernel for the third-generation scanner, patients being monitored for changes in kidney stone volume can undergo scanning performed with second- or third-generation dual-energy CT scanners, and the images obtained can be reconstructed with either filtered back projection or IR without the introduction of bias into kidney stone volume measurements.
authors.affiliation: 1 Department of Radiology, Mayo Clinic, 200 First St SW, Rochester, MN 55905.
authors.forename: Alice E
authors.initials: AE
authors.lastname: Huang
authors.affiliation: 1 Department of Radiology, Mayo Clinic, 200 First St SW, Rochester, MN 55905.
authors.forename: Juan C
authors.initials: JC
authors.lastname: Montoya
authors.affiliation: 1 Department of Radiology, Mayo Clinic, 200 First St SW, Rochester, MN 55905.
authors.forename: Maria
authors.initials: M
authors.lastname: Shiung
authors.affiliation: 1 Department of Radiology, Mayo Clinic, 200 First St SW, Rochester, MN 55905.
authors.forename: Shuai
authors.initials: S
authors.lastname: Leng
authors.affiliation: 1 Department of Radiology, Mayo Clinic, 200 First St SW, Rochester, MN 55905.
authors.forename: Cynthia H
authors.initials: CH
authors.lastname: McCollough
mesh_terms: D000465:Algorithms; D006801:Humans; D007669:Kidney Calculi / Q000000981:diagnostic imaging*; D011446:Prospective Studies; D011829:Radiation Dosage; D011857:Radiographic Image Interpretation, Computer-Assisted / Q000379:methods*; D015898:Tomography Scanners, X-Ray Computed
keywords: CT; iterative reconstruction; nephrolithiasis; renal stone; stone volume