title: Evaluation of endorectal ultrasound (ERUS) and MRI for prediction of circumferential resection margin (CRM) for rectal cancer.
abstract: ERUS and MRI are used for preoperative imaging of rectal cancer. Here, we compare ERUS and MRI for accuracy of CRM prediction at mid- and distal rectal locations. In retrospective review, 20 rectal cancer patients having TME surgery had both ERUS and MRI preoperatively: 8 mid rectum and 12 in distal rectum. Predicted CRM by ERUS and MRI were compared to TME pathology. Overall, predicted CRM was 6.5 ± 3.6 mm by ERUS, 7.7 ± 5.0 mm by MRI, and 6.0 ± 4.6 mm by pathology. Overall, correlation coefficients to pathology were 0.77 (p = 0.0004) for ERUS and 0.64 (p = 0.008) for MRI. In distal rectum, correlation coefficients were 0.71 (p = 0.02) for ERUS and -0.10 (p = 0.79) for MRI. In mid rectum, correlation coefficients were 0.92 (p = 0.01) for ERUS and 0.44 (p = 0.38) for MRI. While MRI is used routinely for preoperative rectal cancer imaging, ERUS can provide additional assessment of CRM for mid or distal rectal lesions. Further investigation is needed to support these preliminary ERUS CRM findings in mid and distal rectum.
authors.affiliation: St Paul's Hospital, University of British Columbia, Vancouver, BC, Canada. Electronic address: Catherine.h.tsai@gmail.com.
authors.forename: Catherine
authors.initials: C
authors.lastname: Tsai
authors.affiliation: St Paul's Hospital, University of British Columbia, Vancouver, BC, Canada. Electronic address: cjhague75@gmail.com.
authors.forename: Cameron
authors.initials: C
authors.lastname: Hague
authors.affiliation: St Paul's Hospital, University of British Columbia, Vancouver, BC, Canada. Electronic address: wei.xiong@ubc.ca.
authors.forename: Wei
authors.initials: W
authors.lastname: Xiong
authors.affiliation: St Paul's Hospital, University of British Columbia, Vancouver, BC, Canada. Electronic address: mraval@providencehealth.bc.ca.
authors.forename: Manoj
authors.initials: M
authors.lastname: Raval
authors.affiliation: St Paul's Hospital, University of British Columbia, Vancouver, BC, Canada. Electronic address: akarimuddin@providencehealth.bc.ca.
authors.forename: Ahmer
authors.initials: A
authors.lastname: Karimuddin
authors.affiliation: St Paul's Hospital, University of British Columbia, Vancouver, BC, Canada. Electronic address: cbrown@providencehealth.bc.ca.
authors.forename: Carl
authors.initials: C
authors.lastname: Brown
authors.affiliation: St Paul's Hospital, University of British Columbia, Vancouver, BC, Canada. Electronic address: tphang@providencehealth.bc.ca.
authors.forename: P Terry
authors.initials: PT
authors.lastname: Phang
mesh_terms: D000230:Adenocarcinoma / Q000000981:diagnostic imaging / Q000601:surgery*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D019160:Endosonography; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D000072662:Margins of Excision; D008875:Middle Aged; D017063:Outcome Assessment, Health Care; D011300:Preoperative Care; D012004:Rectal Neoplasms / Q000000981:diagnostic imaging / Q000601:surgery*; D012189:Retrospective Studies
keywords: Circumferential resection margin; Endorectal ultrasound; MRI; TME surgery