title: [Effect of oxygen tubing connection site on percutaneous oxygen partial pressure and percutaneous carbon dioxide partial pressure in patients with chronic obstructive pulmonary disease during noninvasive positive pressure ventilation].
abstract: Objective:We evaluated the effects of administering oxygen through nasal catheters inside the mask or through the mask on percutaneous oxygen partial pressure (PcO(2))and percutaneous carbon dioxide partial pressure (PcCO(2)) during noninvasive positive pressure ventilation (NPPV) to find a better way of administering oxygen, which could increase PcO(2) by increasing the inspired oxygen concentration.Methods:Ten healthy volunteers and 9 patients with chronic obstructive pulmonary disease complicated by type Ⅱ respiratory failure were included in this study. Oxygen was administered through a nasal catheter inside the mask or through the mask (oxygen flow was 3 and 5 L/min) during NPPV. PcO(2) and PcCO(2) were measured to evaluate the effects of administering oxygen through a nasal catheter inside the mask or through the mask, indirectly reflecting the effects of administering oxygen through nasal catheter inside the mask or through the mask on inspired oxygen concentration.Results:Compared to administering oxygen through the mask during NPPV, elevated PcO(2) was measured in administering oxygen through the nasal catheter inside the mask, and the differences were statistically significant (P<0.05). At the same time, there was no significant change in PcCO(2) (P>0.05).Conclusion:Administering oxygen through a nasal catheter inside the mask during NPPV increased PcO(2) by increasing the inspired oxygen concentration but did not increase PcCO(2). This method of administering oxygen could conserve oxygen and be suitable for family NPPV. Our results also provided theoretical basis for the development of new masks.
authors.affiliation: Affiliated Beijing Chaoyang Hospital of Capital Medical University Beijing Institute of Respiratory Medicine, Beijing 100043, China.
authors.forename: S
authors.initials: S
authors.lastname: Mi
authors.forename: L M
authors.initials: LM
authors.lastname: Zhang
mesh_terms: D002245:Carbon Dioxide / Q000008:administration & dosage*; D016022:Case-Control Studies; D057785:Catheters; D005260:Female; D006801:Humans; D008297:Male; D008397:Masks; D008875:Middle Aged; D063087:Noninvasive Ventilation; D010100:Oxygen / Q000008:administration & dosage*; D010313:Partial Pressure; D011175:Positive-Pressure Respiration; D029424:Pulmonary Disease, Chronic Obstructive / Q000150:complications / Q000628:therapy*; D012131:Respiratory Insufficiency / Q000150:complications / Q000628:therapy*; D016896:Treatment Outcome
chemical_list: D002245:Carbon Dioxide; D010100:Oxygen
keywords: Non-invasive ventilation; Partial pressure, percutaneous