title: Mucoactive and antioxidant medicines for COPD: consensus of a group of Chinese pulmonary physicians.
abstract: Airway mucus hypersecretion is a frequent symptom associated with acute and chronic airway disease. Inhibition of mucus production or promotion of mucolysis not only relieved symptoms but also improved disease outcomes. There are numerous available mucoactive medicines for prescription, and how to select them properly for different diseases is important for clinical practice. So far, there is no one consensus or guideline reported. A group of Chinese pulmonary physicians worked together to complete this consensus based on literature review, summarized mechanism and usage of each classical mucoactive medicine. In general, antioxidant mucoactive medicines play an important role in chronic airway disease, including but not limited to airway mucus clearance, reduced acute exacerbation and improved pulmonary function.
authors.affiliation: Department of Pulmonary and Critical Care Medicine, Second Hospital Affiliated to Hebei Medical University, Hebei.
authors.forename: Xixin
authors.initials: X
authors.lastname: Yan
authors.affiliation: Department of Pulmonary Medicine, Zhongshan Hospital, Fudan University; Shanghai Respiratory Research Institute.
authors.forename: Yuanlin
authors.initials: Y
authors.lastname: Song
authors.affiliation: Department of Pulmonary Medicine, Shanghai 6th People's Hospital, Jiaotong University.
authors.forename: Ce
authors.initials: C
authors.lastname: Shen
authors.affiliation: Department of Respiratory Disease, Peking Union Hospital, Beijing.
authors.forename: Wenbing
authors.initials: W
authors.lastname: Xu
authors.affiliation: Department of Pulmonary and Critical Care Medicine, Beijing 301 Military Hospital, Beijing.
authors.forename: Liangan
authors.initials: L
authors.lastname: Chen
authors.affiliation: Department of Pulmonary Medicine, Xijing Hospital, The Affiliated Hospital of Fourth Military Medical University.
authors.forename: Jian
authors.initials: J
authors.lastname: Zhang
authors.affiliation: Department of Respiratory and Critical Care Medicine, Tongji Hospital, Huazhong University of Science and Technology, Wuhan.
authors.forename: Huiguo
authors.initials: H
authors.lastname: Liu
authors.affiliation: Department of Pulmonary Medicine, Jiangsu Province Hospital, First Affiliated Hospital of Nanjing Medical University, Nanjing.
authors.forename: Mao
authors.initials: M
authors.lastname: Huang
authors.affiliation: Department of Pulmonary and Critical Care Medicine, General Hospital of Fuzhou Military Region, Fuzhou.
authors.forename: Guoxiang
authors.initials: G
authors.lastname: Lai
authors.affiliation: Department of Respiratory Medicine, Xinqiao Hospital, Third Military Medical University, Chongqing.
authors.forename: Guishen
authors.initials: G
authors.lastname: Qian
authors.affiliation: Department of Respiratory Medicine, First Hospital Affiliated to Zhengzhou University, Zhengzhou.
authors.forename: Jing
authors.initials: J
authors.lastname: Wang
authors.affiliation: Department of Respiratory Medicine, People's Hospital of Guizhou Province, Guizhou.
authors.forename: Xianwei
authors.initials: X
authors.lastname: Ye
authors.affiliation: Guangzhou Institute of Respiratory Disease, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, People's Republic of China.
authors.forename: Jinping
authors.initials: J
authors.lastname: Zheng
authors.affiliation: Department of Pulmonary Medicine, Zhongshan Hospital, Fudan University.
authors.forename: Chunxue
authors.initials: C
authors.lastname: Bai
mesh_terms: D000975:Antioxidants / Q000009:adverse effects / Q000627:therapeutic use*; D002681:China; D018450:Disease Progression; D005100:Expectorants / Q000009:adverse effects / Q000627:therapeutic use*; D006801:Humans; D008168:Lung / Q000187:drug effects* / Q000378:metabolism / Q000503:physiopathology; D009079:Mucociliary Clearance / Q000187:drug effects*; D009093:Mucus / Q000378:metabolism*; D029424:Pulmonary Disease, Chronic Obstructive / Q000175:diagnosis / Q000188:drug therapy* / Q000503:physiopathology; D000072106:Pulmonologists; D011788:Quality of Life; D020127:Recovery of Function; D016896:Treatment Outcome
chemical_list: D000975:Antioxidants; D005100:Expectorants
keywords: chronic bronchitis; mucolysis; sputum