title: [The differential diagnosis and treatment of depressive disorders in climacteric transition].
abstract: OBJECTIVE
  To study clinical symptoms of menopause depression, develop differential diagnostic criteria and consider treatment aspects.
  
  
  METHODS
  One hundred and fifty women, aged 41-65 years, with mental disorders developed in different periods of menopause (perimenopause, menopause and post menopause) were studied.
  
  
  CONCLUSIONS
  Four types of depression were diagnosed: climacteric (n=46), psychogenic (n=35), endogenic (n=42) and involutional (n=27). Clinical characteristics of each type are presented in the aspect of correlations between psychopathological and climacteric (somatic) symptoms. Therapy of the depressions is discussed in light of literature on psychopharmacological, hormonal treatment and psychotherapy. The efficacy of antidepressants, in particular valdoxan (agomelatine), is highlighted.
authors.affiliation: Sechenov First Moscow State Medical University, Moscow, Russia.
authors.forename: N A
authors.initials: NA
authors.lastname: Tyuvina
authors.affiliation: Sechenov First Moscow State Medical University, Moscow, Russia.
authors.forename: V V
authors.initials: VV
authors.lastname: Balabanova
authors.affiliation: Sechenov First Moscow State Medical University, Moscow, Russia.
authors.forename: E O
authors.initials: EO
authors.lastname: Voronina
mesh_terms: D000328:Adult; D000368:Aged; D002979:Climacteric / Q000523:psychology*; D003863:Depression / Q000175:diagnosis* / Q000628:therapy*; D003866:Depressive Disorder / Q000175:diagnosis* / Q000628:therapy*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008593:Menopause / Q000523:psychology; D008875:Middle Aged; D017698:Postmenopause; D011613:Psychotherapy