title: Multigene profiling of single circulating tumor cells.
abstract: Numerous techniques for isolating circulating tumor cells (CTCs) have been developed. Concurrently, single-cell techniques that can reveal molecular components of CTCs have become widely available. We discuss how the combination of isolation and multigene profiling of single CTCs in our platform can facilitate eventual translation to the clinic.
authors.affiliation: Department of Radiology, Stanford University School of Medicine, Stanford, CA, USA; Molecular Imaging Program at Stanford, Stanford University School of Medicine, Stanford, CA, USA.
authors.forename: Seung-Min
authors.initials: SM
authors.lastname: Park
authors.affiliation: Department of Electrical Engineering, Stanford University , Stanford, CA, USA.
authors.forename: Dawson J
authors.initials: DJ
authors.lastname: Wong
authors.affiliation: Department of Chemical Engineering, Stanford University , Stanford, CA, USA.
authors.forename: Chin Chun
authors.initials: CC
authors.lastname: Ooi
authors.affiliation: Department of Chemistry, Stanford University , Stanford, CA, USA.
authors.forename: Jared C
authors.initials: JC
authors.lastname: Nesvet
authors.affiliation: Department of Radiology, Stanford University School of Medicine, Stanford, CA, USA; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA; Canary Center at Stanford for Cancer Early Detection, Stanford University School of Medicine, Palo Alto, CA, USA.
authors.forename: Viswam S
authors.initials: VS
authors.lastname: Nair
authors.affiliation: Department of Electrical Engineering, Stanford University, Stanford, CA, USA; Department of Materials Science and Engineering, Stanford University, Stanford, CA, USA; Canary Center at Stanford for Cancer Early Detection, Stanford University School of Medicine, Palo Alto, CA, USA.
authors.forename: Shan X
authors.initials: SX
authors.lastname: Wang
authors.affiliation: Department of Radiology, Stanford University School of Medicine, Stanford, CA, USA; Molecular Imaging Program at Stanford, Stanford University School of Medicine, Stanford, CA, USA; Canary Center at Stanford for Cancer Early Detection, Stanford University School of Medicine, Palo Alto, CA, USA.
authors.forename: Sanjiv S
authors.initials: SS
authors.lastname: Gambhir
keywords: Circulating tumor cells; rare-cell sorting; single-cell analysis