title: Chondroblastic and fibroblastic osteosarcoma of the jaws: Report of two cases and review of literature.
abstract: This study aims to report of two variants of gnathic osteosarcoma with highlights on the varied histopathological presentation of osteosarcomas (OS). OS present with diverse histological appearances. Despite significant advances in molecular pathogenesis and biomarkers, clinicopathologic correlation is still considered as the important criteria in diagnosis. Chondroblastic osteosarcoma in a 52-year-old female and fibroblastic osteosarcoma in a 35-year-old female. Osteosarcoma is a relatively rare disease of the oral and maxillofacial region. Regular screening and follow-up is highly recommended, as recurrence rates are higher. Thorough understanding of the histologic spectrum of osteosarcoma reduces the diagnostic difficulties in categorizing the OS and separating these neoplasms from benign bone diseases.
authors.affiliation: Department of Oral Pathology and Microbiology, Mamatha Dental College, Khammam, Andhrapradesh, India.
authors.forename: Sudheerkanth Kondamari
authors.initials: SK
authors.lastname: Peddana
authors.affiliation: Department of Oral Pathology and Microbiology, SRM Dental College, Chennai, Tamil Nadu, India.
authors.forename: Ramya
authors.initials: R
authors.lastname: Ramadas
authors.affiliation: Department of Oral Pathology and Microbiology, St.Gregorius Dental College, Kothamangalam, Kerala, India.
authors.forename: Eapen
authors.initials: E
authors.lastname: Cherian
authors.affiliation: Department of Oral Pathology, SRM Dental College, SRM University, Chennai, Tamil Nadu, India.
authors.forename: Dineshkumar
authors.initials: D
authors.lastname: Thayalan
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007573:Jaw Neoplasms / Q000145:classification / Q000175:diagnosis / Q000473:pathology*; D008339:Mandibular Neoplasms / Q000145:classification / Q000175:diagnosis / Q000473:pathology; D008875:Middle Aged; D012516:Osteosarcoma / Q000145:classification / Q000175:diagnosis / Q000473:pathology*; D010486:Periapical Tissue / Q000473:pathology; D011862:Radiography, Panoramic; D013223:Statistics as Topic