title: [Toxic epidermal necrolysis (Lyell syndrome), a lifethreatening emergency of introgenic origin].
abstract: Cutaneous drug eruptions are frequently encoun¬tered. Their putative diagnosis is based on a set of imputability arguments. The histopathological aspect is often suggestive of the dermatosis nature, and varies according to the type of drug reaction. Some drug eruptions follow a benign course, but others including the toxic epidermal necrolysis are severe and life-threatening. It corresponds to a dermatological emer¬gency to be managed in a specialized burn unit.
authors.affiliation: Service de Dermatopathologie, CHU de Liège, site du Sart Tilman, Belgique.|Laboratoire LABIC, Département des Sciences cliniques, Université de Liège. Belgique.
authors.forename: G E
authors.initials: GE
authors.lastname: Piérard
authors.affiliation: Unité des Brûlés, Hôpital Militaire Reine Astrid, Neder-over-Heembeek, Liège, Belgique.
authors.forename: S
authors.initials: S
authors.lastname: Jennes
authors.affiliation: Service de Dermatologie, CHU de Liège, site du Sart Tilman, Liège, Belgique.
authors.forename: C
authors.initials: C
authors.lastname: Piérard-Franchimont
mesh_terms: D000465:Algorithms; D003937:Diagnosis, Differential; D003875:Drug Eruptions / Q000175:diagnosis* / Q000628:therapy; D004630:Emergencies; D006801:Humans; D007049:Iatrogenic Disease; D013262:Stevens-Johnson Syndrome / Q000175:diagnosis* / Q000628:therapy
keywords:  Drug ;  Drug eruption ;  Drug imputability ;  Drug toxicity ;  Lyell syndrome;  Toxic epidermal necrolysis 