title: Lactobacillus coryniformisCausing Pulmonary Infection in a Patient with Metastatic Small Cell Carcinoma: Case Report and Review of Literature onLactobacillusPleuro-Pulmonary Infections.
abstract: Lactobacilli are normal commensals of the gastrointestinal and female genital tract. Due to its low virulence these bacteria are known to cause opportunistic infections. They cause mostly bacteraemia with or without endocarditis and rarely cause pleuro-pulmonary infection. We report a case ofLactobacillus coryniformispleuro-pulmonary infection and review 14 previously reported cases of lactobacilli causing pleuro-pulmonary infections. Our patient had small cell carcinoma with metastasis. All the 14 cases had pre-existing risk factors like immunosuppresion, cancer or chronic disease. There was no consensus on choice of antimicrobial agents to be used. Different species of lactobacilli were involved. Available susceptibility data showed that lactobacilli species were more susceptible to ampicillin, erythromycin, gentamycin, and clindamycin and decreased to ceftriaxone, ciprofloxacin and trimethoprim-sulphamethoxazole. Isolation ofLactobacillusspecies from a case of pleuro-pneumonia infection could be a marker of poor long-term prognosis. The diagnosis of these infections requires both microbiologist and clinical correlation to rule out contamination.
authors.affiliation: Assistant Professor, Department of Microbiology, Government Medical College and Hospital , Chandigarh, India .
authors.forename: Priya
authors.initials: P
authors.lastname: Datta
authors.affiliation: Professor, Department of Microbiology, Government Medical College and Hospital , Chandigarh, India .
authors.forename: Varsha
authors.initials: V
authors.lastname: Gupta
authors.affiliation: Senior Resident, Department of Microbiology, Government Medical College and Hospital , Chandigarh, India .
authors.forename: Gursimran Kaur
authors.initials: GK
authors.lastname: Mohi
authors.affiliation: Professor and Head, Department of Microbiology, Government Medical College and Hospital , Chandigarh, India .
authors.forename: Jagdish
authors.initials: J
authors.lastname: Chander
authors.affiliation: Professor and Head, Department of Pulmonary Medicine, Government Medical College and Hospital , Chandigarh, India .
authors.forename: Ashok Kumar
authors.initials: AK
authors.lastname: Janmeja
keywords: Ampicillin; Bacteraemia; Commensals; Immunosuppression