title: One Less Painful Procedure: Using Umbilical Cord Blood as Alternative Source to Admission Complete Blood Count.
abstract: ObjectiveThis study aims to evaluate the use of umbilical cord blood as an alternative to the admission complete blood count (CBC) in the well-appearing late preterm neonates admitted to the neonatal intensive care unit.Study DesignPaired umbilical cord and admission blood CBC samples from well late preterm infants were compared using a two-samplet-test or analysis of variance with an unequal variance for differences in the hemoglobin, platelet counts, white blood cell, and absolute neutrophil counts.ResultsA total of 100 infants were enrolled in the study. The study included 46 females, 5 Asian, 9 Black, 35 Hispanic, 51 White, with a mean gestational age of 35.3 ± 1 weeks (range: 34-36.5 weeks), and a mean birth weight of 2,347 ± 491 g (range: 1,840-4,260 g). Around 80% were appropriate for gestational age, 5% were large for gestational age, and 15% were small for gestational age. The median difference between the cord and admission blood samples were hemoglobin: 1.1 g/dL, platelet: 7.50 × 103cells/μL, white blood cell count: 2.3 × 103cells/μL, and absolute neutrophil count: 0.6 × 103cells/μL.ConclusionThe cord and admission blood testing were not statistically or clinically different when compared. In well late preterm infants, the NICU admission blood CBC may be replaced with an umbilical cord blood CBC.
authors.affiliation: Department of Pediatrics, Stony Brook Children's Hospital, Stony Brook, New York.
authors.forename: Neera
authors.initials: N
authors.lastname: Prakash
authors.affiliation: Department of Pediatrics, Stony Brook Children's Hospital, Stony Brook, New York.
authors.forename: Joseph
authors.initials: J
authors.lastname: Decristofaro
authors.affiliation: Department of Pediatrics, Stony Brook Children's Hospital, Stony Brook, New York.
authors.forename: Echezona T
authors.initials: ET
authors.lastname: Maduekwe
mesh_terms: D001772:Blood Cell Count; D001800:Blood Specimen Collection / Q000379:methods*; D005260:Female; D005312:Fetal Blood; D005865:Gestational Age; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature / Q000097:blood*; D007236:Infant, Small for Gestational Age / Q000097:blood; D008297:Male; D010146:Pain; D011446:Prospective Studies
chemical_list: D006454:Hemoglobins