title: Antimicrobial activity of aqueous extracts from four plants on bacterial isolates from periodontitis patients.
abstract: Four aqueous extracts of different plant organs are the following: Artemisia herba-alba, Opuntia ficus-indica, Camellia sinensis and Phlomis crinita were evaluated against two bacterial strains: Porphyromonas gingivalis and Prevotella intermedia, which are implicated in periodontal diseases. By using a disc method, these plant extracts demonstrated powerful bacterial activity against these Gram-negative strains. The minimum inhibitory concentration values of the four plant extracts varied between 0.03 and 590.82 mg/ml for the microbes. Another assay using commercial antibiotics and antibacterials as positive controls was also conducted. Values obtained after statistical analysis of inhibition diameters of all plant extracts demonstrated that for P. gingivalis, the aqueous extracts of A. herba-alba and O. ficus-indica were most effective, followed by those of C. sinensis and P. crinita. For P. intermedia, aqueous extracts of O. ficus-indica and C. sinensis appeared to be more efficient with significantly different (P > 0.05) inhibition diameters, followed by those of O. ficus-indica and P. crinita. In summary, the statistical results reveal that these plant extracts exert stronger antibacterial activity on P. intermedia germ as compared to P. gingivalis.
authors.affiliation: Ecole Nationale Polytechnique d'Alger, Laboratoire BIOGEP, B.P. 182-16200, El Harrach, Alger, Algeria.
authors.forename: Leila
authors.initials: L
authors.lastname: Arbia
authors.affiliation: Ecole Nationale Polytechnique d'Alger, Laboratoire BIOGEP, B.P. 182-16200, El Harrach, Alger, Algeria.|Ecole Nationale Superieure Veterinaire d'Alger, BP 161, 16200, El Harrach, Alger, Algeria.
authors.forename: Nassima
authors.initials: N
authors.lastname: Chikhi-Chorfi
authors.affiliation: Institut Pasteur d'Algérie, Service des Anaérobies, Route du petit staouéli, Dély-Brahim, Algeria.
authors.forename: Ilhem
authors.initials: I
authors.lastname: Betatache
authors.affiliation: Laboratoire de Toxicologie, Faculté de Pharmacie, Université de Paris V, 4 avenus de l'Observatoire, 75006, Paris, France.
authors.forename: Chuong
authors.initials: C
authors.lastname: Pham-Huy
authors.affiliation: Ecole Nationale Polytechnique d'Alger, Laboratoire BIOGEP, B.P. 182-16200, El Harrach, Alger, Algeria.
authors.forename: Selma
authors.initials: S
authors.lastname: Zenia
authors.affiliation: Ecole Nationale Polytechnique d'Alger, Laboratoire BIOGEP, B.P. 182-16200, El Harrach, Alger, Algeria.|Département Génie chimique, Université de Technologie de Compiègne, B.P. 20.509, 60205, Compiègne Cedex, France.
authors.forename: Nabil
authors.initials: N
authors.lastname: Mameri
authors.affiliation: Centre de Recherche en Technologie des Semi-conducteurs de l 'Energetique (crtse), Algiers, Algeria. nadjibdrouiche@yahoo.fr.|Department of Environmental Engineering 2, Technology of Semi-conductor for the Energetic Research Center, Bd Frantz Fanon BP140 Alger-7-merveilles, 16038, Algiers, Algeria. nadjibdrouiche@yahoo.fr.
authors.forename: Nadjib
authors.initials: N
authors.lastname: Drouiche
authors.affiliation: Ecole Nationale Polytechnique d'Alger, Laboratoire BIOGEP, B.P. 182-16200, El Harrach, Alger, Algeria.|Université de Bouira, Bouira, Algeria.
authors.forename: Hakim
authors.initials: H
authors.lastname: Lounici
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology; D000890:Anti-Infective Agents / Q000494:pharmacology*; D006801:Humans; D010510:Periodontal Diseases; D010518:Periodontitis; D010936:Plant Extracts / Q000494:pharmacology; D016966:Porphyromonas gingivalis; D018713:Prevotella intermedia
chemical_list: D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D010936:Plant Extracts
keywords: Antibacterial activity; Artemisia herba-alba; Camellia sinensis; Opuntia ficus-indica; Phlomis crinita; Porphyromonas gingivalis; Prevotella intermedia