title: Rhodium-Catalyzed meta-C-H Functionalization of Arenes.
abstract: Rhodium-catalyzed ortho-C-H functionalization is well known in the literature. Described herein is the Xphos-supported rhodium catalysis of meta-C-H olefination of benzylsulfonic acid and phenyl acetic acid frameworks with the assistance of a para-methoxy-substituted cyano phenol as the directing group. Complete mono-selectivity is observed for both scaffolds. A wide range of olefins and functional groups attached to arene are tolerated in this protocol.
authors.affiliation: Department of Chemistry, Indian Institute of Technology Bombay, Powai, Mumbai-, 400076, India.
authors.forename: Milan
authors.initials: M
authors.lastname: Bera
authors.affiliation: Department of Chemistry, Indian Institute of Technology Bombay, Powai, Mumbai-, 400076, India.
authors.forename: Soumitra
authors.initials: S
authors.lastname: Agasti
authors.affiliation: Department of Chemistry, Indian Institute of Technology Bombay, Powai, Mumbai-, 400076, India.
authors.forename: Rajdip
authors.initials: R
authors.lastname: Chowdhury
authors.affiliation: Department of Chemistry, Indian Institute of Technology Bombay, Powai, Mumbai-, 400076, India.
authors.forename: Rahul
authors.initials: R
authors.lastname: Mondal
authors.affiliation: Department of Chemistry, Indian Institute of Technology Bombay, Powai, Mumbai-, 400076, India.
authors.forename: Debasis
authors.initials: D
authors.lastname: Pal
authors.affiliation: Department of Chemistry, Indian Institute of Technology Bombay, Powai, Mumbai-, 400076, India.
authors.forename: Debabrata
authors.initials: D
authors.lastname: Maiti
keywords: C−H activation; reaction kinetics; reaction mechanisms; regioselectivity; rhodium