title: CADASIL: two new cases with intracerebral hemorrhage.
abstract: Whether cerebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a risk factor for spontaneous intracerebral hemorrhage (ICH) and influences outcomes remains unclear. In this study, we report two cases of CADASIL presenting with cerebral hemorrhages. These cases suggest that a CADASIL vasculopathy by itself mainly results in ICH, as indicated by slight vascular risk factors and prominent neuroimaging abnormalities, suggesting that CADASIL should be considered a risk factor for ICH. Interestingly, decreased perihematomal edema was noted in ICH patients with CADASIL in this study.
authors.affiliation: Department of Neurology Beijing Tiantan Hospital Capital Medical University Beijing 100050 China.
authors.forename: Chen
authors.initials: C
authors.lastname: Zhang
authors.affiliation: Department of Neurology Beijing Tiantan Hospital Capital Medical University Beijing 100050 China.
authors.forename: Wei
authors.initials: W
authors.lastname: Li
authors.affiliation: Beijing Neurosurgical Institute Capital Medical University Beijing 100050 China.
authors.forename: Shaowu
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authors.lastname: Li
authors.affiliation: Department of Neurology Beijing Tiantan Hospital Capital Medical University Beijing 100050 China.
authors.forename: Songtao
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authors.lastname: Niu
authors.affiliation: Department of Neurology Beijing Tiantan Hospital Capital Medical University Beijing 100050 China.
authors.forename: Xingao
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authors.lastname: Wang
authors.affiliation: Department of Neurology Beijing Tiantan Hospital Capital Medical University Beijing 100050 China.
authors.forename: Hefei
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authors.lastname: Tang
authors.affiliation: Department of Neurology Beijing Tiantan Hospital Capital Medical University Beijing 100050 China.
authors.forename: Xueying
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authors.lastname: Yu
authors.affiliation: Department of Neurology Beijing Tiantan Hospital Capital Medical University Beijing 100050 China.
authors.forename: Bin
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authors.lastname: Chen
authors.affiliation: Department of Neurology Beijing Tiantan Hospital Capital Medical University Beijing 100050 China.
authors.forename: Yuzhi
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authors.lastname: Shi
authors.affiliation: Department of Neurology Beijing Tiantan Hospital Capital Medical University Beijing 100050 China.
authors.forename: Qihua
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authors.lastname: Chen
authors.affiliation: Department of Neurology Beijing Tiantan Hospital Capital Medical University Beijing 100050 China.
authors.forename: Liying
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authors.lastname: Guo
authors.affiliation: Department of Neurology Beijing Tiantan Hospital Capital Medical University Beijing 100050 China.
authors.forename: Yunzhu
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authors.lastname: Pan
authors.affiliation: Department of Neurology Beijing Tiantan Hospital Capital Medical University Beijing 100050 China.
authors.forename: Yilong
authors.initials: Y
authors.lastname: Wang
authors.affiliation: Department of Neurology Beijing Tiantan Hospital Capital Medical University Beijing 100050 China.
authors.forename: Zaiqiang
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authors.lastname: Zhang