title: C3-Selective alkenylation of N-acylindoles with unactivated internal alkynes by cooperative nickel/aluminium catalysis.
abstract: Highly regio- and stereoselective alkenylation of N-acylindoles with unactivated internal alkynes has been accomplished by cooperative nickel/aluminium catalysis to afford C3-alkenylated indoles. Coordination of the acyl moiety to a bulky aluminium-based Lewis acid plays a crucial role in the selective functionalization at the C3-position by electron-rich nickel(0) catalysis.
authors.affiliation: Department of Material Chemistry, Graduate School of Engineering, Kyoto University, Katsura, Nishikyo-ku, Kyoto 615-8510, Japan. nakao.yoshiaki.8n@kyoto-u.ac.jp.
authors.forename: Fumiyoshi
authors.initials: F
authors.lastname: Inoue
authors.forename: Teruhiko
authors.initials: T
authors.lastname: Saito
authors.forename: Kazuhiko
authors.initials: K
authors.lastname: Semba
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Nakao