title: Successful treatment of infertility in a female Sumatran orangutan Pongo abelii.
abstract: In 2011, a female Sumatran orangutan housed at Durrell Wildlife Conservation Trust became infertile following a massive antepartum hemorrhage in labor and the delivery of a stillborn infant. The placenta was infected with Pantoea sp. Hysterosalpingography (HSG) revealed blocked fallopian tubes, and pressurized fallopian tube perfusion was used to reverse the tubal occlusion. She subsequently conceived and following an intensive training program, we were able to measure umbilical artery waveform analysis for fetal well-being and placental localization to exclude placenta previa, which could complicate pregnancy and lead to catastrophic hemorrhage. The female went on to deliver a healthy offspring. We suggest that these techniques should be considered for other infertile females in the global captive population.
authors.affiliation: Assisted Reproduction Unit/Anaesthetics, Jersey General Hospital, St. Helier, Jersey, Channel Islands.
authors.forename: Neil
authors.initials: N
authors.lastname: Maclachlan
authors.affiliation: Durrell Wildlife Conservation Trust, Trinity, Jersey, Channel Islands.
authors.forename: Gordon
authors.identifier: http://orcid.org/0000-0002-6838-8326
authors.initials: G
authors.lastname: Hunt
authors.affiliation: Durrell Wildlife Conservation Trust, Trinity, Jersey, Channel Islands.|Bristol Zoological Society Ltd., Clifton, Bristol, UK.
authors.forename: Sarah
authors.initials: S
authors.lastname: Fowkes
authors.affiliation: Durrell Wildlife Conservation Trust, Trinity, Jersey, Channel Islands.
authors.forename: Melissa
authors.initials: M
authors.lastname: Frost
authors.affiliation: Assisted Reproduction Unit/Anaesthetics, Jersey General Hospital, St. Helier, Jersey, Channel Islands.
authors.forename: John
authors.initials: J
authors.lastname: Miller
authors.affiliation: Assisted Reproduction Unit/Anaesthetics, Jersey General Hospital, St. Helier, Jersey, Channel Islands.
authors.forename: Gari
authors.initials: G
authors.lastname: Purcell-Jones
authors.affiliation: Assisted Reproduction Unit/Anaesthetics, Jersey General Hospital, St. Helier, Jersey, Channel Islands.
authors.forename: Peter
authors.initials: P
authors.lastname: Sullivan
authors.affiliation: Durrell Wildlife Conservation Trust, Trinity, Jersey, Channel Islands.
authors.forename: Alberto
authors.initials: A
authors.lastname: Barbon
authors.affiliation: Durrell Wildlife Conservation Trust, Trinity, Jersey, Channel Islands.
authors.forename: Andrew
authors.initials: A
authors.lastname: Routh
authors.affiliation: Durrell Wildlife Conservation Trust, Trinity, Jersey, Channel Islands.|Chester Zoo, Chester, UK.
authors.forename: Francisco J
authors.initials: FJ
authors.lastname: López
authors.affiliation: Durrell Wildlife Conservation Trust, Trinity, Jersey, Channel Islands.
authors.forename: Eluned C
authors.initials: EC
authors.lastname: Price
mesh_terms: D000818:Animals; D000836:Animals, Zoo; D018420:Ape Diseases / Q000000981:diagnostic imaging / Q000209:etiology / Q000628:therapy*; D005184:Fallopian Tube Diseases / Q000000981:diagnostic imaging / Q000628:therapy / Q000662:veterinary*; D005260:Female; D007047:Hysterosalpingography / Q000662:veterinary; D007247:Infertility, Female / Q000000981:diagnostic imaging / Q000209:etiology / Q000628:therapy / Q000662:veterinary*; D010477:Perfusion / Q000662:veterinary; D057080:Pongo abelii / Q000502:physiology*; D011247:Pregnancy; D016896:Treatment Outcome; D014592:Uterine Hemorrhage / Q000150:complications / Q000662:veterinary*
keywords: hysterosalpingography (HSG); operant conditioning; pressurized fallopian tube perfusion; proximal tube obstruction (PTO); ultrasound