title: Evaluation of different treatment protocols for dentin hypersensitivity: an 18-month randomized clinical trial.
abstract: This randomized and longitudinal in vivo study aimed to assess different protocols for the treatment of dentin hypersensitivity with low-power laser (with different doses), high-power laser, and a desensitizing agent, for a period of 12 and 18 months. The lesions from 32 patients (117 lesions), who were submitted to the inclusion and exclusion criteria, were divided into nine groups (n = 13): G1: Gluma Desensitizer (Heraeus Kulzer), G2: low-power laser with low dose (three points of irradiation in vestibular portion and an apical point 30 mW, 10 J/cm2, 9 s per point with the wavelength of 810 nm, with three sessions with an interval of 72 h), G3: low-power laser with high dose (one point in the cervical area, and one apical point 100 mW, 40 J/cm2, 11 s per point with the wavelength of 810 nm in three sessions with an interval of 72 h), G4: low-power laser with low dose + Gluma Desensitizer, G5: low-power laser with high dose + Gluma Desensitizer, G6: Nd:YAG laser (Power Laser™ ST6, Research® in contact 1.0 W, 10 Hz and 100 mJ, ≈85 J/cm2, with the wavelength of 1064 nm), G7: Nd:YAG laser + Gluma Desensitizer, G8: low-power laser with low dose + Nd:YAG laser, and G9: low-power laser with high dose + Nd:YAG laser. The level of sensitivity of each volunteer was assessed by visual analog scale of pain (VAS) with the aid of air from the triple syringe and exploration probe, 12 and 18 months after treatment. All analyses were performed separately for air and probe stimulus. The level of significance was considered for values of p < 0.05. After statistical analysis, all treatments were shown to be effective in reducing dentinal hypersensitivity, and the results were considered not statistically different from those at 12 months. Therefore, until the 18-month evaluation, it could be said that no statistical differences were observed in the sensitivity levels for all treatments.
authors.affiliation: Department of Restorative Dentistry/Special Laboratory of Lasers (LELO), School of Dentistry, University of São Paulo, Av. Prof. Lineu Prestes, 2227, Cidade Universitária, São Paulo, SP, 05580-900, Brazil. anelyol@gmail.com.|Special Laboratory of Lasers in Dentistry, Department of Restorative Dentistry, School of Dentistry, University of São Paulo, Av. Prof. Lineu Prestes 2227, São Paulo, SP, 05508-000, Brazil. anelyol@gmail.com.
authors.forename: Anely Oliveira
authors.initials: AO
authors.lastname: Lopes
authors.affiliation: Department of Restorative Dentistry/Special Laboratory of Lasers (LELO), School of Dentistry, University of São Paulo, Av. Prof. Lineu Prestes, 2227, Cidade Universitária, São Paulo, SP, 05580-900, Brazil.
authors.forename: Carlos
authors.initials: C
authors.lastname: de Paula Eduardo
authors.affiliation: Department of Restorative Dentistry/Special Laboratory of Lasers (LELO), School of Dentistry, University of São Paulo, Av. Prof. Lineu Prestes, 2227, Cidade Universitária, São Paulo, SP, 05580-900, Brazil.
authors.forename: Ana Cecília Correa
authors.initials: ACC
authors.lastname: Aranha
mesh_terms: D000328:Adult; D000388:Air; D003804:Dentin / Q000528:radiation effects; D003807:Dentin Sensitivity / Q000532:radiotherapy / Q000628:therapy*; D005976:Glutaral / Q000627:therapeutic use; D006801:Humans; D053844:Lasers, Solid-State; D008137:Longitudinal Studies; D028022:Low-Level Light Therapy; D008689:Methacrylates / Q000627:therapeutic use; D008875:Middle Aged; D010147:Pain Measurement; D055815:Young Adult
chemical_list: D008689:Methacrylates; C111486:gluma desensitizer; D005976:Glutaral
keywords: Dentin hypersensitivity; Desensitizing; Laser; Non-carious cervical lesion