title: [Finasteride adverse effects: An update].
abstract: Finasteride is a 5-α reductase inhibitor that is widely used in the management of benign prostate hyperplasia and male pattern hair loss. It is well known that these agents improve the quality of life in men suffering from these conditions. However, they are associated with some transient and even permanent adverse effects. The aim of this article is to clarify the controversies about the safety of finasteride by analyzing the evidence available in the literature.
authors.affiliation: Departamento de Dermatología, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.
authors.forename: Néstor
authors.initials: N
authors.lastname: Carreño-Orellana
authors.affiliation: Pontificia Universidad Católica de Chile, Santiago, Chile.
authors.forename: Catherina
authors.initials: C
authors.lastname: Moll-Manzur
authors.affiliation: Departamento de Dermatología, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.
authors.forename: Juan Eduardo
authors.initials: JE
authors.lastname: Carrasco-Zuber
authors.affiliation: Departamento de Dermatología, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.
authors.forename: Sergio
authors.initials: S
authors.lastname: Álvarez-Véliz
authors.affiliation: Pontificia Universidad Católica de Chile, Santiago, Chile.
authors.forename: Daniela
authors.initials: D
authors.lastname: Berroeta-Mauriziano
authors.affiliation: Departamento de Dermatología, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.
authors.forename: Ninoska
authors.initials: N
authors.lastname: Porras-Kusmanic
mesh_terms: D058891:5-alpha Reductase Inhibitors / Q000009:adverse effects* / Q000627:therapeutic use; D000505:Alopecia / Q000188:drug therapy; D001786:Blood Glucose / Q000378:metabolism; D007172:Erectile Dysfunction / Q000139:chemically induced; D018120:Finasteride / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D050356:Lipid Metabolism / Q000187:drug effects; D008297:Male; D011470:Prostatic Hyperplasia / Q000188:drug therapy; D011471:Prostatic Neoplasms / Q000517:prevention & control; D013091:Spermatogenesis / Q000187:drug effects
chemical_list: D058891:5-alpha Reductase Inhibitors; D001786:Blood Glucose; D018120:Finasteride