title: The contemporary distribution of Trypanosoma cruzi infection in humans, alternative hosts and vectors.
abstract: Chagas is a potentially fatal chronic disease affecting large numbers of people across the Americas and exported throughout the world through human population movement. It is caused by the Trypanosoma cruzi parasite, which is transmitted by triatomine vectors to humans and a wide range of alternative host species. The database described here was compiled to allow the risk of vectorial transmission to humans to be mapped using geospatial models. The database collates all available records, published since 2003, for prevalence and occurrence of infection in humans, vectors and alternative hosts, and links each record to a defined time and location. A total of 16,802 records of infection have been extracted from the published literature and unpublished sources. The resulting database can be used to improve our understanding of the geographic variation in vector infection prevalence and to estimate the risk of vectorial transmission of T. cruzi to humans.
authors.affiliation: Oxford Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford OX3 7BN, UK.
authors.forename: Annie J
authors.initials: AJ
authors.lastname: Browne
authors.affiliation: Sanaria Institute for Global Health and Tropical Medicine, Rockville, Maryland 20850, USA.
authors.forename: Carlos A
authors.initials: CA
authors.lastname: Guerra
authors.affiliation: Secretaria de Vigilância em Saúde, Ministério da Saúde, Brasília, Distrito Federal 70058-900, Brasil.
authors.forename: Renato Vieira
authors.identifier: 0000-0002-1660-0807
authors.initials: RV
authors.lastname: Alves
authors.affiliation: Secretaria de Vigilância em Saúde, Ministério da Saúde, Brasília, Distrito Federal 70058-900, Brasil.
authors.forename: Veruska Maia
authors.initials: VM
authors.lastname: da Costa
authors.affiliation: School of Biosciences, Durham University, Durham DH1 3LE, UK.
authors.forename: Anne L
authors.initials: AL
authors.lastname: Wilson
authors.affiliation: Institute for Health Metrics and Evaluation, University of Washington, Seattle, Washington 98121, USA.
authors.forename: David M
authors.initials: DM
authors.lastname: Pigott
authors.affiliation: Oxford Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford OX3 7BN, UK.|Institute for Health Metrics and Evaluation, University of Washington, Seattle, Washington 98121, USA.
authors.forename: Simon I
authors.identifier: 0000-0002-0611-7272
authors.initials: SI
authors.lastname: Hay
authors.affiliation: School of Biosciences, Durham University, Durham DH1 3LE, UK.
authors.forename: Steve W
authors.initials: SW
authors.lastname: Lindsay
authors.affiliation: School of Biosciences, University of Melbourne, Parkville, Victoria 3010, Australia.
authors.forename: Nick
authors.initials: N
authors.lastname: Golding
authors.affiliation: Oxford Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford OX3 7BN, UK.
authors.forename: Catherine L
authors.identifier: 0000-0002-8028-4079
authors.initials: CL
authors.lastname: Moyes
mesh_terms: D000818:Animals; D014355:Chagas Disease / Q000453:epidemiology*; D062306:Geography, Medical; D006801:Humans; D007303:Insect Vectors; D014349:Trypanosoma cruzi