title: INFLUENCE OF MALE OBESITY ON FERTILITY.
abstract: The aim of this review is to analyze current diagnostic approaches to obesity in
  adult men, the potential mechanisms linking obesity to infertility, and treatment options aimed at
  improving reproductive health. Obesity has become a worldwide epidemic with the estimated prevalence
  increasing from 28.8% to 36.9% between 1980 and 2013. In terms of diagnosis, numerous
  simple techniques have been developed including body mass index, waist to hip ratio, waist circumference,
  bioelectrical impedance analysis, ultrasound and skinfold measurements. Additionally, several
  other less available but more accurate techniques have been suggested, such as air displacement plethysmography,
  dual energy x-ray absorptiometry, computed tomography and magnetic resonance imaging.
  In addition to cardiovascular and other disorders, male obesity can negatively affect the male reproductive
  potential through abnormal reproductive hormone levels, reduced semen quality, increased
  release of adipose-derived hormones and adipokines, as well as thermal, genetic and sexual mechanisms.
  In the management of obesity related male infertility, natural weight loss is the cornerstone and
  regular exercise the first-line treatment. Although bariatric surgery results in greater improvements in
  weight loss outcomes when compared to non-surgical interventions, further research is required to
  clarify its overall influence on male fertility.
authors.forename: Miro
authors.initials: M
authors.lastname: Kasum
authors.forename: Sonja
authors.initials: S
authors.lastname: Anić-Jurica
authors.forename: Ermin
authors.initials: E
authors.lastname: Čehić
authors.forename: Tajana
authors.initials: T
authors.lastname: Klepac-Pulanić
authors.forename: Josip
authors.initials: J
authors.lastname: Juras
authors.forename: Kristina
authors.initials: K
authors.lastname: Žužul
mesh_terms: D054392:Adipokines; D000328:Adult; D001823:Body Composition; D015992:Body Mass Index; D006801:Humans; D007248:Infertility, Male / Q000175:diagnosis* / Q000209:etiology*; D008297:Male; D009765:Obesity / Q000150:complications* / Q000175:diagnosis*; D055101:Semen Analysis; D055105:Waist Circumference
chemical_list: D054392:Adipokines