title: JCL roundtable: Managing lipid disorders in patients with HIV.
abstract: The HIV-AIDS epidemic has provided one of the more challenging problems in treatment of infectious diseases. As antiretroviral drugs made a very marked improvement in controlling the immunodeficiency state and patients gained in their longevity, the concern with lipid abnormalities came to the fore. The initial drugs produced a form of metabolic syndrome accompanied by very elevated plasma triglyceride concentrations. Furthermore, the drugs used to control the virus were often metabolized in a manner that interfered with lipid lowering drug therapy. The antiviral agents have improved in many respects and the experience in managing the lipid disorders has added greatly to our ability to control these problems as well. This roundtable discussion has been conducted with 4 physicians who have been involved in management of large cohorts of patients with HIV infection and who have had a special interest in reduction of vascular disease risk.
authors.affiliation: Emory University School of Medicine, Atlanta, GA, USA. Electronic address: wbrow925@bellsouth.net.
authors.forename: W Virgil
authors.initials: WV
authors.lastname: Brown
authors.affiliation: Icahn School of Medicine at Mount Sinai, New York, NY, USA.
authors.forename: Judith A
authors.initials: JA
authors.lastname: Aberg
authors.affiliation: Brown University Alpert Medical School, Providence, RI, USA.
authors.forename: Karen E
authors.initials: KE
authors.lastname: Aspry
authors.affiliation: Case Western Reserve University School of Medicine, Cleveland, OH, USA.
authors.forename: Chris T
authors.initials: CT
authors.lastname: Longenecker
authors.affiliation: Columbia University College of Physicians and Surgeons, New York, NY, USA.
authors.forename: Merle
authors.initials: M
authors.lastname: Myerson
mesh_terms: D015658:HIV Infections / Q000150:complications*; D006801:Humans; D052439:Lipid Metabolism Disorders / Q000150:complications*; D005791:Patient Care / Q000379:methods*
keywords: AIDS; Antiretroviral drugs; HIV; Immunodeficiency; Infectious diseases; Lipid disorders