title: 18F-Fluorocholine, 18F-FDG, and 18F-Fluoroethyl Tyrosine PET/CT in Parathyroid Cancer.
abstract: We report on a 71-year-old woman presenting with biochemical features indicating recurrent disease in long-term follow-up of left-sided parathyroid carcinoma. She had undergone several surgical procedures including total thyroidectomy, partial resection of the esophageal wall, and curative neck radiation 12 years previously. PET/CT using F-fluorocholine revealed high uptake in local relapse in the lower neck, comparable to F-FDG, whereas only faint uptake was observed with F-fluoroethyl tyrosine. As shown in this case, imaging with FDG and F-fluorocholine is feasible in (recurrent) parathyroid carcinoma and clearly superior to F-fluoroethyl tyrosine.
authors.affiliation: From the *Clinical Institute of Nuclear Medicine and Endocrinology, and †Central Radiology Institute, Kepler University Hospital, Med. Campus III, Linz, Austria; ‡Medical Faculty of the University of Erlangen, Germany; and §Department of Nuclear Medicine, Medical University of Innsbruck, Innsbruck, Austria.
authors.forename: Margit
authors.initials: M
authors.lastname: Hatzl
authors.forename: Julia C
authors.initials: JC
authors.lastname: Röper-Kelmayr
authors.forename: Franz A
authors.initials: FA
authors.lastname: Fellner
authors.forename: Michael
authors.initials: M
authors.lastname: Gabriel
mesh_terms: D000368:Aged; D002794:Choline / Q000031:analogs & derivatives*; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D010282:Parathyroid Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D000072078:Positron Emission Tomography Computed Tomography; D012008:Recurrence; D013965:Thyroidectomy; D014443:Tyrosine / Q000031:analogs & derivatives*
chemical_list: D019788:Fluorodeoxyglucose F18; C545932:(18F)fluoroethyltyrosine; D014443:Tyrosine; C514960:fluorocholine; D002794:Choline