title: Apparent Diffusion Coefficient (ADC) of the vitreous humor and Susceptibility Weighted Imaging (SWI) of the retina in abused children with retinal hemorrhages.
abstract: This study speculated that the apparent diffusion coefficient (ADC) of the vitreous humor might be altered in the setting of abusive head trauma (AHT) with retinal hemorrhages (RH). Fourty-four subjects were analyzed (n=20 AHT cases; n=24 controls). There was no statistically significant difference in normalized ADC values between the cases and controls (-0.14 and -0.08 respectively, p=0.46), but analysis of RH by susceptibility weighted imaging (SWI) compared to dilated funduscopic exam demonstrated statistically significant correlation (p=0.003 and 0.012). Our results suggest that SWI serves as a more sensitive diagnostic tool for detection of ocular injury in AHT than ADC.
authors.affiliation: Department of Radiology at the University of Pittsburgh Medical Center (UPMC), Pittsburgh, Pennsylvania, United States.
authors.forename: Misun
authors.initials: M
authors.lastname: Hwang
authors.affiliation: Department of Neurosurgery at University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States.
authors.forename: Samuel S
authors.initials: SS
authors.lastname: Shin
authors.affiliation: Johns Hopkins University School of Medicine, Baltimore, Maryland, United States.
authors.forename: Matthew A
authors.initials: MA
authors.lastname: Thimm
authors.affiliation: Department of Radiology at the University of Pittsburgh Medical Center (UPMC), Pittsburgh, Pennsylvania, United States.
authors.forename: Anish
authors.initials: A
authors.lastname: Ghodadra
authors.affiliation: Department of Ophthalmology at Children's Hospital of Pittsburgh UPMC, Pittsburgh, Pennsylvania, United States.
authors.forename: Christin L
authors.initials: CL
authors.lastname: Sylvester
authors.affiliation: Department of Ophthalmology at Children's Hospital of Pittsburgh UPMC, Pittsburgh, Pennsylvania, United States.
authors.forename: Ken
authors.initials: K
authors.lastname: Nischal
authors.affiliation: Department of Radiology at Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania, United States.
authors.forename: Ashok
authors.initials: A
authors.lastname: Panigrahy
authors.affiliation: Department of Radiology at Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania, United States. Electronic address: zuccolig@upmc.edu.
authors.forename: Giulio
authors.initials: G
authors.lastname: Zuccoli
mesh_terms: D002649:Child Abuse; D006259:Craniocerebral Trauma / Q000150:complications / Q000000981:diagnostic imaging / Q000473:pathology*; D005260:Female; D006801:Humans; D007223:Infant; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D008297:Male; D012160:Retina / Q000000981:diagnostic imaging / Q000473:pathology*; D012166:Retinal Hemorrhage / Q000000981:diagnostic imaging / Q000209:etiology / Q000473:pathology*; D012189:Retrospective Studies; D014822:Vitreous Body / Q000000981:diagnostic imaging / Q000473:pathology*
keywords: Abusive head trauma; Apparent diffusion coefficient; Child abuse; Susceptibility weighted imaging; Vitreous