title: Lynch Syndrome and Endometrial Cancer.
abstract: In patients with Lynch syndrome, gynecologic cancer often can be the first presenting malignancy. In this review, we summarize the genetics of Lynch syndrome and review the various modalities of identifying patients at risk for this syndrome. The clinical characteristics of Lynch-associated endometrial cancer and screening and risk-reducing strategies also are described.
authors.affiliation: From the Department of OB/GYN, Division of Gynecologic Oncology, MetroHealth Medical Center, Cleveland, Ohio.
authors.forename: Sareena
authors.initials: S
authors.lastname: Singh
authors.affiliation: From the Department of OB/GYN, Division of Gynecologic Oncology, MetroHealth Medical Center, Cleveland, Ohio.
authors.forename: Kimberly E
authors.initials: KE
authors.lastname: Resnick
mesh_terms: D003123:Colorectal Neoplasms, Hereditary Nonpolyposis / Q000150:complications* / Q000209:etiology / Q000235:genetics; D016889:Endometrial Neoplasms / Q000209:etiology* / Q000235:genetics; D005260:Female; D006801:Humans; D012307:Risk Factors