title: Biopsy-proven hypersensitivity pneumonitis caused by a fluorocarbon waterproofing spray.
abstract: We present the case of a 35-year-old male who developed a chronic hypersensitivity pneumonitis (HP) following inhalational exposure to a fluorocarbon waterproofing aerosol spray, caused by his work for an upholstery and soft furnishings retailer. This is the first case report from inhalational fluorocarbon exposure with histological evidence of chronic HP. This is then discussed in the context of previous reports of interstitial lung disease and lung injury, caused by similar occupational and non-occupational exposures.
authors.affiliation: Occupational Lung Disease Service, Birmingham Heartlands Hospital, Bordesley Green East, Birmingham B9 5SS, UK.
authors.forename: G I
authors.initials: GI
authors.lastname: Walters
authors.affiliation: Department of Histopathology, Birmingham Heartlands Hospital, Bordesley Green East, Birmingham B9 5SS, UK.
authors.forename: S
authors.initials: S
authors.lastname: Trotter
authors.affiliation: Department of Pathology, University Hospitals Coventry and Warwickshire, Clifford Bridge Road, Coventry CV2 2DX, UK.
authors.forename: B
authors.initials: B
authors.lastname: Sinha
authors.affiliation: Occupational Lung Disease Service, Birmingham Heartlands Hospital, Bordesley Green East, Birmingham B9 5SS, UK.
authors.forename: Z
authors.initials: Z
authors.lastname: Richmond
authors.affiliation: Occupational Lung Disease Service, Birmingham Heartlands Hospital, Bordesley Green East, Birmingham B9 5SS, UK.
authors.forename: P S
authors.initials: PS
authors.lastname: Burge
mesh_terms: D000328:Adult; D000542:Alveolitis, Extrinsic Allergic / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology; D001706:Biopsy; D005466:Fluorocarbons / Q000633:toxicity*; D006801:Humans; D019570:Inhalation Exposure / Q000009:adverse effects; D008168:Lung / Q000473:pathology; D017563:Lung Diseases, Interstitial; D008297:Male; D016273:Occupational Exposure / Q000009:adverse effects*
chemical_list: D005466:Fluorocarbons
keywords: Hypersensitivity pneumonitis; occupational chemicals; occupational respiratory disease; toxic inhalation.