title: Successful Continuation of Pregnancy After Treatment of Group A Streptococci Sepsis.
abstract: Invasive group A streptococci infections in pregnancy have historically led to severe maternal and neonatal morbidity and mortality. We are reporting a rare and novel case of successful treatment of third-trimester group A streptococci infection with early, aggressive intervention and maintenance of the pregnancy to term.
  
  
  
  A 35 year old woman initially presented with fever, flu-like symptoms, and preterm contractions at 34 weeks of gestation. She demonstrated signs of early stages of septic shock, ultimately attributed to group A streptococci bacteremia. Early, aggressive intervention allowed the pregnancy to continue until 38 weeks of gestation with normal maternal and neonatal outcomes.
  
  
  
  Early and aggressive treatment of invasive group A streptococci infection during pregnancy can potentially avoid severe maternal and perinatal morbidity and mortality with a successful continuation of pregnancy.
authors.affiliation: Department of Obstetrics and Gynecology, Wayne State University School of Medicine, Detroit, Michigan.
authors.forename: Ali
authors.initials: A
authors.lastname: Alhousseini
authors.forename: Mia E
authors.initials: ME
authors.lastname: Layne
authors.forename: Bernard
authors.initials: B
authors.lastname: Gonik
authors.forename: David
authors.initials: D
authors.lastname: Bryant
authors.forename: Sanjay
authors.initials: S
authors.lastname: Patwardhan
authors.forename: Manasi
authors.initials: M
authors.lastname: Patwardhan
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D016470:Bacteremia / Q000175:diagnosis* / Q000188:drug therapy; D002981:Clindamycin / Q000008:administration & dosage / Q000627:therapeutic use*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007262:Infusions, Intravenous; D008297:Male; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis* / Q000188:drug therapy; D011263:Pregnancy Trimester, Third; D011296:Prenatal Diagnosis; D013289:Streptococcaceae / Q000302:isolation & purification*; D013290:Streptococcal Infections / Q000175:diagnosis* / Q000188:drug therapy
chemical_list: D000900:Anti-Bacterial Agents; D002981:Clindamycin