title: Mantle Cell Lymphoma: Contemporary Diagnostic and Treatment Perspectives in the Age of Personalized Medicine.
abstract: Mantle cell lymphoma is a clinically heterogeneous disease occurring within a heterogeneous patient population, highlighting a need for personalized therapy to ensure optimal outcomes. It is therefore critical to understand the benefits and risks associated with both intensive and deintensified approaches. In the following review we provide a therapeutic roadmap to strategically guide treatment for newly diagnosed and relapsed/refractory patients highlighting pivotal and recently published results involving known and novel therapies.
authors.affiliation: Department of Malignant Hematology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA. Electronic address: jose.sandoval@moffitt.org.
authors.forename: Jose D
authors.initials: JD
authors.lastname: Sandoval-Sus
authors.affiliation: Department of Hematology/Oncology, George Washington University, Washington, D.C., USA.
authors.forename: Eduardo M
authors.initials: EM
authors.lastname: Sotomayor
authors.affiliation: Department of Malignant Hematology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA.
authors.forename: Bijal D
authors.initials: BD
authors.lastname: Shah
mesh_terms: D006801:Humans; D020522:Lymphoma, Mantle-Cell / Q000175:diagnosis* / Q000628:therapy*; D057285:Precision Medicine; D011379:Prognosis
keywords: Mantle cell lymphoma; Prognosis; Treatment