title: Water Clear Cell Adenoma of the Parathyroid Gland: A Forgotten Cause of Primary Hyperparathyroidism.
abstract: Water clear cell adenoma of the parathyroid gland is a rare neoplasm composed of large clear cells with foamy cytoplasm and mild nuclear pleomorphism, compressing the residual nonneoplastic parathyroid tissue. The differential diagnosis includes a variety of neoplasms with clear cell features. In this article, we provide an overview of the entity with a historical perspective, in order to help pathologists in distinguishing it from other neoplasms in their daily practice.
authors.affiliation: 1 Mount Sinai Medical Center, Miami Beach, FL, USA.
authors.forename: Siba
authors.initials: S
authors.lastname: El Hussein
authors.affiliation: 1 Mount Sinai Medical Center, Miami Beach, FL, USA.
authors.forename: Robert
authors.initials: R
authors.lastname: Poppiti
mesh_terms: D000236:Adenoma / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D002292:Carcinoma, Renal Cell / Q000175:diagnosis / Q000473:pathology; D003593:Cytoplasm / Q000473:pathology; D003937:Diagnosis, Differential; D006801:Humans; D049950:Hyperparathyroidism, Primary / Q000473:pathology*; D008854:Microscopy, Electron; D010280:Parathyroid Glands / Q000166:cytology / Q000473:pathology / Q000648:ultrastructure; D010282:Parathyroid Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D035583:Rare Diseases / Q000473:pathology*; D012468:Salivary Gland Neoplasms / Q000175:diagnosis / Q000473:pathology
keywords: parathyroid adenoma; parathyroid gland; wasserhelle cells; water clear cell parathyroid adenoma; water clear cells