title: Struma Ovarii With Hyperthyroidism.
abstract: We report the case of a 61-year-old woman with persistent thyrotoxicosis for 7 years despite low thyroidal radioiodine uptake and methimazole treatment. Her initial I whole-body scan (WBS) was read as negative. Upon evaluation in our institution, she remained hyperthyroid after discontinuation of methimazole. Repeat WBS with SPECT/CT revealed low 24-hour thyroidal uptake (RAIU = 2%) and intensely focal radioiodine uptake in a large heterogeneous left pelvic mass, consistent with left adnexal struma ovarii. Resection of this mass confirmed benign struma ovarii. This case illustrates the advantage of fusion SPECT/CT imaging with planar I-WBS for diagnosis of extrathyroidal thyrotoxicosis.
authors.affiliation: From the *Division of Metabolism, Endocrinology and Diabetes, Department of Internal Medicine, †Nuclear Medicine, Department of Radiology, and ‡Department of Pathology, University of Michigan, Ann Arbor, MI.
authors.forename: Lynn P
authors.initials: LP
authors.lastname: Ang
authors.forename: Anca M
authors.initials: AM
authors.lastname: Avram
authors.forename: Richard W
authors.initials: RW
authors.lastname: Lieberman
authors.forename: Nazanene H
authors.initials: NH
authors.lastname: Esfandiari
mesh_terms: D005260:Female; D006801:Humans; D007457:Iodine Radioisotopes; D008713:Methimazole / Q000627:therapeutic use; D008875:Middle Aged; D000072098:Single Photon Emission Computed Tomography Computed Tomography; D013330:Struma Ovarii / Q000150:complications* / Q000000981:diagnostic imaging*; D013971:Thyrotoxicosis / Q000150:complications* / Q000188:drug therapy; D051598:Whole Body Imaging
chemical_list: D007457:Iodine Radioisotopes; D008713:Methimazole