title: Demographic and Comorbidity Pattern of Patients with Critical Limb Ischemia.
abstract: OBJECTIVE
  The present study aimed at identifying the pattern of patients with critical limb ischemia (CLI) compared with those with peripheral arterial occlusive disease (PAOD).
  
  
  METHODS
  A four-year retrospective study was conducted with patients hospitalized in the Second Surgical Clinic at the Emergency County Hospital Cluj-Napoca. The medical charts of patients with PAOD (n=466) and CLI (n=223) were reviewed and data were collected.
  
  
  RESULTS
  The study included 689 patients; mean age 67 years for PAOD patients and 65 years for CLI patients. A significantly higher percentage of patients were male in both groups (79.25%, P < 0.0001). Most of the patients in both groups had received at least a secondary education (P < 0.0001). Most of the subjects in both groups were smokers (>71.30%) with no difference between groups (P = 0.566). No significant differences were found between the groups in comorbidities (diabetes, arterial blood hypertension, cardiac ischemia, rhythm disorders, P > 0.05). There were more CLI patients that were overweight than overweight patients with PAOD (P = 0.0004). High serum cholesterol (>200 mg/dL) and triglycerides (>150 mg/dL) levels were found in the CLI group (P < 0.05). Age was identified as a risk factors for amputation (OR = 1.03, 95%Cl [1.01-1.05], P = 0.0012).
  
  
  CONCLUSIONS
  The profile of a patient with critical limb ischemia and peripheral arterial occlusive disease is a 65-67-year-old male smoker with at least a secondary education. The CLI patient is overweight with pathological serum levels of cholesterol and triglycerides.
authors.affiliation: Department of Medical Informatics and Biostatistics, Iuliu Haţieganu University of Medicine and Pharmacy Cluj-Napoca, 6 Louis Pasteur St., Cluj-Napoca, 400685 Romania.
authors.forename: Răzvan A
authors.initials: RA
authors.lastname: Ciocan
authors.affiliation: Department of Medical Informatics and Biostatistics, Iuliu Haţieganu University of Medicine and Pharmacy Cluj-Napoca, 6 Louis Pasteur St., Cluj-Napoca, 400685.
authors.forename: Sorana D
authors.initials: SD
authors.lastname: Bolboacă
authors.affiliation: Department of Surgery II, Iuliu Haţieganu University of Medicine and Pharmacy Cluj-Napoca.
authors.forename: Şerban
authors.initials: Ş
authors.lastname: Rădulescu
authors.affiliation: Department of Surgery II, Iuliu Haţieganu University of Medicine and Pharmacy Cluj-Napoca.
authors.forename: Bogdan
authors.initials: B
authors.lastname: Stancu
authors.affiliation: Department of Vascular Surgery, Emergency County Hospital Cluj-Napoca.
authors.forename: Andra
authors.initials: A
authors.lastname: Ciocan
authors.affiliation: Department of Surgery II, Iuliu Haţieganu University of Medicine and Pharmacy Cluj-Napoca, Romania.
authors.forename: Claudia D
authors.initials: CD
authors.lastname: Gherman
mesh_terms: D017677:Age Distribution; D000368:Aged; D000671:Amputation, Surgical; D000925:Anticoagulants / Q000627:therapeutic use; D001145:Arrhythmias, Cardiac / Q000453:epidemiology; D001157:Arterial Occlusive Diseases / Q000097:blood / Q000453:epidemiology* / Q000628:therapy; D002784:Cholesterol / Q000097:blood; D015897:Comorbidity; D003920:Diabetes Mellitus / Q000453:epidemiology; D004522:Educational Status; D005121:Extremities / Q000098:blood supply*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000453:epidemiology*; D007511:Ischemia / Q000097:blood / Q000453:epidemiology* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000453:epidemiology*; D050177:Overweight / Q000453:epidemiology; D058729:Peripheral Arterial Disease / Q000097:blood / Q000453:epidemiology* / Q000628:therapy; D011453:Prostaglandins / Q000627:therapeutic use; D012189:Retrospective Studies; D012307:Risk Factors; D012907:Smoking / Q000453:epidemiology*; D014665:Vasodilator Agents / Q000627:therapeutic use
chemical_list: D000925:Anticoagulants; D011453:Prostaglandins; D014665:Vasodilator Agents; D002784:Cholesterol
keywords: amputation; critical limb ischemia (CLI); peripheral arterial occlusive disease (PAOD); risk factor