title: Domino N-/C-Arylation via In Situ Generation of a Directing Group: Atom-Efficient Arylation Using Diaryliodonium Salts.
abstract: Both aryl components of diaryliodonium salts can be used in a domino one-pot reaction via in situ generation of a directing group. A number of heterocycles undergo N-arylation which is followed by ruthenium-catalyzed C-arylation. Notably the reaction extends well to unsymmetrical diaryliodonium salts with a number of highly selective examples shown.
authors.affiliation: School of Chemistry, The University of Manchester, Oxford Road, Manchester, M13 9PL, UK.
authors.forename: Christopher J
authors.identifier: 0000-0003-0776-5674
authors.initials: CJ
authors.lastname: Teskey
authors.affiliation: School of Chemistry, The University of Manchester, Oxford Road, Manchester, M13 9PL, UK.
authors.forename: Shariar M A
authors.initials: SMA
authors.lastname: Sohel
authors.affiliation: School of Chemistry, The University of Manchester, Oxford Road, Manchester, M13 9PL, UK.
authors.forename: Danielle L
authors.identifier: 0000-0002-5992-7025
authors.initials: DL
authors.lastname: Bunting
authors.affiliation: School of Chemistry, The University of Manchester, Oxford Road, Manchester, M13 9PL, UK.
authors.forename: Sachin G
authors.initials: SG
authors.lastname: Modha
authors.affiliation: School of Chemistry, The University of Manchester, Oxford Road, Manchester, M13 9PL, UK.
authors.forename: Michael F
authors.identifier: 0000-0001-9633-1135
authors.initials: MF
authors.lastname: Greaney
keywords: C-H activation; N-heterocycles; arylation; iodonium compounds