title: Severe reactive ischemic posterior segment inflammation in Acanthamoeba keratitis: Case report of a patient with Sjögren's syndrome.
abstract: OBJECTIVE
  We report on a case of Acanthamoeba keratitis (AK)-related reactive ischemic posterior segment inflammation following intraocular surgery in a patient with primary Sjögren's syndrome (PSS).
  
  
  METHODS
  A 48-year-old female patient with severe protracted AK underwent uneventful cataract surgery upon development of a corneal scar. Four weeks postoperatively, she experienced a rapid loss of vision to no light perception. Central retinal artery occlusion and ischemic optic neuropathy could be excluded, and a diagnosis of PSS was made. The condition remained unresponsive to systemic steroid treatment and ultimately led to enucleation of the globe. Histologic work-up revealed ischemic posterior segment inflammation and Acanthamoeba cysts in the corneal stroma.
  
  
  CONCLUSIONS
  Autoimmune disease may be a risk factor for AK-related severe reactive ischemic posterior segment inflammation, and intraocular surgery can be a trigger to its manifestation.
authors.affiliation: Department of Ophthalmology, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria.
authors.forename: Christoph
authors.initials: C
authors.lastname: Palme
authors.affiliation: Department of Ophthalmology, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria.
authors.forename: Bernhard
authors.initials: B
authors.lastname: Steger
authors.affiliation: Department of Ophthalmology, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria.
authors.forename: Gertrud
authors.initials: G
authors.lastname: Haas
authors.affiliation: Department of Ophthalmology, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria.
authors.forename: Barbara
authors.initials: B
authors.lastname: Teuchner
authors.affiliation: Department of Ophthalmology, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria.
authors.forename: Nikolaos E
authors.initials: NE
authors.lastname: Bechrakis
keywords: Acanthamoeba keratitis; Cataract surgery; Reactive ischemic posterior segment inflammation; Sjögren’s syndrome