title: Evaluation of forensic genetic parameters of 12 STR loci in the Korean population using the InvestigatorⓇHDplex kit.
abstract: We genotyped and calculated the forensic parameters of 10 non-CODIS loci and 2 CODIS loci of 990 Korean individuals using the InvestigatorⓇHDplex kit. No significant deviations from Hardy-Weinberg equilibrium (after Bonferroni correction for multiple testing) or genetic linkage disequilibrium were observed. The calculated matching probability and power of discrimination ranged from 0.0080 to 0.2014, and 0.7986 to 0.9920, respectively. We conclude that the markers of the kit are highly informative corroborative tools for forensic DNA analysis.
authors.affiliation: Forensic DNA Division, National Forensic Service, Wonju, 26460, Republic of Korea.
authors.forename: Ju Yeon
authors.initials: JY
authors.lastname: Jung
authors.affiliation: DNA Analysis Division, Seoul Institute, National Forensic Service, Seoul, 08636, Republic of Korea.
authors.forename: Eun Hye
authors.initials: EH
authors.lastname: Kim
authors.affiliation: Forensic DNA Division, National Forensic Service, Wonju, 26460, Republic of Korea.
authors.forename: Yu-Li
authors.initials: YL
authors.lastname: Oh
authors.affiliation: Forensic DNA Division, National Forensic Service, Wonju, 26460, Republic of Korea.
authors.forename: Hyun-Chul
authors.initials: HC
authors.lastname: Park
authors.affiliation: Forensic DNA Division, National Forensic Service, Wonju, 26460, Republic of Korea.
authors.forename: Jung Ho
authors.initials: JH
authors.lastname: Hwang
authors.affiliation: Forensic DNA Division, National Forensic Service, Wonju, 26460, Republic of Korea. neobios@korea.kr.
authors.forename: Si-Keun
authors.initials: SK
authors.lastname: Lim
mesh_terms: D044466:Asian People / Q000235:genetics*; D016172:DNA Fingerprinting / Q000295:instrumentation*; D005787:Gene Frequency; D005828:Genetics, Population; D005838:Genotype; D006801:Humans; D018895:Microsatellite Repeats; D016133:Polymerase Chain Reaction / Q000295:instrumentation*; D056910:Republic of Korea
keywords: Forensic genetic parameters; InvestigatorⓇ HDplex kit; Korean population