title: PSMA-PET/CT-Positive Paget Disease in a Patient with Newly Diagnosed Prostate Cancer: Imaging and Bone Biopsy Findings.
abstract: A 67-year-old man diagnosed with Gleason score 4 + 5 = 9 clinically localized prostate cancer with68Ga-labeled prostate-specific membrane antigen-targeted ligand positron emission tomography/computed tomography (PSMA-PET/CT) positive Paget bone disease is described. Immunohistochemical staining revealed weak PSMA positivity of the bone lesion supporting the hypothesis that neovasculature might explain positive PSMA-PET/CT findings in Paget disease.
authors.affiliation: Departments of Urology, University Hospital "Carl Gustav Carus", Technische Universität Dresden, Fetscherstrasse 74, 01307 Dresden, Germany.
authors.forename: Michael
authors.identifier: 0000-0002-6064-3345
authors.initials: M
authors.lastname: Froehner
authors.affiliation: Departments of Pathology, University Hospital "Carl Gustav Carus", Technische Universität Dresden, Fetscherstrasse 74, 01307 Dresden, Germany.
authors.forename: Marieta
authors.initials: M
authors.lastname: Toma
authors.affiliation: Departments of Nuclear Medicine, University Hospital "Carl Gustav Carus", Technische Universität Dresden, Fetscherstrasse 74, 01307 Dresden, Germany.
authors.forename: Klaus
authors.initials: K
authors.lastname: Zöphel
authors.affiliation: Departments of Urology, University Hospital "Carl Gustav Carus", Technische Universität Dresden, Fetscherstrasse 74, 01307 Dresden, Germany.
authors.forename: Vladimir
authors.initials: V
authors.lastname: Novotny
authors.affiliation: Departments of Radiologic Diagnostics, University Hospital "Carl Gustav Carus", Technische Universität Dresden, Fetscherstrasse 74, 01307 Dresden, Germany.
authors.forename: Michael
authors.initials: M
authors.lastname: Laniado
authors.affiliation: Departments of Urology, University Hospital "Carl Gustav Carus", Technische Universität Dresden, Fetscherstrasse 74, 01307 Dresden, Germany.
authors.forename: Manfred P
authors.identifier: 0000-0002-3094-4227
authors.initials: MP
authors.lastname: Wirth