title: Regulation of Strigolactone Biosynthesis by Gibberellin Signaling.
abstract: Strigolactones (SLs) are a class of plant hormones that regulate diverse physiological processes, including shoot branching and root development. They also act as rhizosphere signaling molecules to stimulate the germination of root parasitic weeds and the branching of arbuscular mycorrhizal fungi. Although various types of cross talk between SLs and other hormones have been reported in physiological analyses, the cross talk between gibberellin (GA) and SLs is poorly understood. We screened for chemicals that regulate the level of SLs in rice (Oryza sativa) and identified GA as, to our knowledge, a novel SL-regulating molecule. The regulation of SL biosynthesis by GA is dependent on the GA receptor GID1 and F-box protein GID2. GA treatment also reduced the infection of rice plants by the parasitic plant witchers weed (Striga hermonthica). These data not only demonstrate, to our knowledge, the novel plant hormone cross talk between SL and GA, but also suggest that GA can be used to control parasitic weed infections.
authors.affiliation: Department of Bioscience, Faculty of Applied Bioscience, Tokyo University of Agriculture, Setagaya, Tokyo 156-8502, Japan (S.I., Y.S., Shu.Y.).|Department of Applied Biological Chemistry, The University of Tokyo, Bunkyo, Tokyo 113-8657, Japan (S.I., D.Y., T.A.).|Department of Applied Biosciences, Faculty of Life Sciences, Toyo University, Ora-gun, Gunma 374-0193, Japan (M.U.).|Graduate School of Life Sciences, Tohoku University, Aoba-ku, Sendai 980-8577, Japan (A.H., Shi.Y.).|RIKEN Center for Sustainable Resource Science, Tsurumi, Yokohama 230-0045, Japan (Sa.Y., K.S.).|Graduate School of Biological Sciences, Nara Institute of Science and Technology, Ikoma, Nara 630-0192, Japan (Sa.Y.).|Department of Agricultural and Environmental Biology, The University of Tokyo, Bunkyo, Tokyo 113-8657 Japan (J.K.).|Bioscience and Biotechnology Center, Nagoya University, Nagoya 464-8601, Japan (M.U.-T., M.M.).|Japan Science and Technology Agency , Core Research for Evolutional Science and Technology (CREST), Kawaguchi-shi, Saitama 332-0012 Japan (T.A.); and.|Department of Biochemistry, King Abdulaziz University, Jeddah 21589, Saudi Arabia (T.A.).
authors.forename: Shinsaku
authors.initials: S
authors.lastname: Ito
authors.affiliation: Department of Bioscience, Faculty of Applied Bioscience, Tokyo University of Agriculture, Setagaya, Tokyo 156-8502, Japan (S.I., Y.S., Shu.Y.).|Department of Applied Biological Chemistry, The University of Tokyo, Bunkyo, Tokyo 113-8657, Japan (S.I., D.Y., T.A.).|Department of Applied Biosciences, Faculty of Life Sciences, Toyo University, Ora-gun, Gunma 374-0193, Japan (M.U.).|Graduate School of Life Sciences, Tohoku University, Aoba-ku, Sendai 980-8577, Japan (A.H., Shi.Y.).|RIKEN Center for Sustainable Resource Science, Tsurumi, Yokohama 230-0045, Japan (Sa.Y., K.S.).|Graduate School of Biological Sciences, Nara Institute of Science and Technology, Ikoma, Nara 630-0192, Japan (Sa.Y.).|Department of Agricultural and Environmental Biology, The University of Tokyo, Bunkyo, Tokyo 113-8657 Japan (J.K.).|Bioscience and Biotechnology Center, Nagoya University, Nagoya 464-8601, Japan (M.U.-T., M.M.).|Japan Science and Technology Agency , Core Research for Evolutional Science and Technology (CREST), Kawaguchi-shi, Saitama 332-0012 Japan (T.A.); and.|Department of Biochemistry, King Abdulaziz University, Jeddah 21589, Saudi Arabia (T.A.).
authors.forename: Daichi
authors.initials: D
authors.lastname: Yamagami
authors.affiliation: Department of Bioscience, Faculty of Applied Bioscience, Tokyo University of Agriculture, Setagaya, Tokyo 156-8502, Japan (S.I., Y.S., Shu.Y.).|Department of Applied Biological Chemistry, The University of Tokyo, Bunkyo, Tokyo 113-8657, Japan (S.I., D.Y., T.A.).|Department of Applied Biosciences, Faculty of Life Sciences, Toyo University, Ora-gun, Gunma 374-0193, Japan (M.U.).|Graduate School of Life Sciences, Tohoku University, Aoba-ku, Sendai 980-8577, Japan (A.H., Shi.Y.).|RIKEN Center for Sustainable Resource Science, Tsurumi, Yokohama 230-0045, Japan (Sa.Y., K.S.).|Graduate School of Biological Sciences, Nara Institute of Science and Technology, Ikoma, Nara 630-0192, Japan (Sa.Y.).|Department of Agricultural and Environmental Biology, The University of Tokyo, Bunkyo, Tokyo 113-8657 Japan (J.K.).|Bioscience and Biotechnology Center, Nagoya University, Nagoya 464-8601, Japan (M.U.-T., M.M.).|Japan Science and Technology Agency , Core Research for Evolutional Science and Technology (CREST), Kawaguchi-shi, Saitama 332-0012 Japan (T.A.); and.|Department of Biochemistry, King Abdulaziz University, Jeddah 21589, Saudi Arabia (T.A.).
authors.forename: Mikihisa
authors.initials: M
authors.lastname: Umehara
authors.affiliation: Department of Bioscience, Faculty of Applied Bioscience, Tokyo University of Agriculture, Setagaya, Tokyo 156-8502, Japan (S.I., Y.S., Shu.Y.).|Department of Applied Biological Chemistry, The University of Tokyo, Bunkyo, Tokyo 113-8657, Japan (S.I., D.Y., T.A.).|Department of Applied Biosciences, Faculty of Life Sciences, Toyo University, Ora-gun, Gunma 374-0193, Japan (M.U.).|Graduate School of Life Sciences, Tohoku University, Aoba-ku, Sendai 980-8577, Japan (A.H., Shi.Y.).|RIKEN Center for Sustainable Resource Science, Tsurumi, Yokohama 230-0045, Japan (Sa.Y., K.S.).|Graduate School of Biological Sciences, Nara Institute of Science and Technology, Ikoma, Nara 630-0192, Japan (Sa.Y.).|Department of Agricultural and Environmental Biology, The University of Tokyo, Bunkyo, Tokyo 113-8657 Japan (J.K.).|Bioscience and Biotechnology Center, Nagoya University, Nagoya 464-8601, Japan (M.U.-T., M.M.).|Japan Science and Technology Agency , Core Research for Evolutional Science and Technology (CREST), Kawaguchi-shi, Saitama 332-0012 Japan (T.A.); and.|Department of Biochemistry, King Abdulaziz University, Jeddah 21589, Saudi Arabia (T.A.).
authors.forename: Atsushi
authors.initials: A
authors.lastname: Hanada
authors.affiliation: Department of Bioscience, Faculty of Applied Bioscience, Tokyo University of Agriculture, Setagaya, Tokyo 156-8502, Japan (S.I., Y.S., Shu.Y.).|Department of Applied Biological Chemistry, The University of Tokyo, Bunkyo, Tokyo 113-8657, Japan (S.I., D.Y., T.A.).|Department of Applied Biosciences, Faculty of Life Sciences, Toyo University, Ora-gun, Gunma 374-0193, Japan (M.U.).|Graduate School of Life Sciences, Tohoku University, Aoba-ku, Sendai 980-8577, Japan (A.H., Shi.Y.).|RIKEN Center for Sustainable Resource Science, Tsurumi, Yokohama 230-0045, Japan (Sa.Y., K.S.).|Graduate School of Biological Sciences, Nara Institute of Science and Technology, Ikoma, Nara 630-0192, Japan (Sa.Y.).|Department of Agricultural and Environmental Biology, The University of Tokyo, Bunkyo, Tokyo 113-8657 Japan (J.K.).|Bioscience and Biotechnology Center, Nagoya University, Nagoya 464-8601, Japan (M.U.-T., M.M.).|Japan Science and Technology Agency , Core Research for Evolutional Science and Technology (CREST), Kawaguchi-shi, Saitama 332-0012 Japan (T.A.); and.|Department of Biochemistry, King Abdulaziz University, Jeddah 21589, Saudi Arabia (T.A.).
authors.forename: Satoko
authors.identifier: http://orcid.org/0000-0002-9999-7861
authors.initials: S
authors.lastname: Yoshida
authors.affiliation: Department of Bioscience, Faculty of Applied Bioscience, Tokyo University of Agriculture, Setagaya, Tokyo 156-8502, Japan (S.I., Y.S., Shu.Y.).|Department of Applied Biological Chemistry, The University of Tokyo, Bunkyo, Tokyo 113-8657, Japan (S.I., D.Y., T.A.).|Department of Applied Biosciences, Faculty of Life Sciences, Toyo University, Ora-gun, Gunma 374-0193, Japan (M.U.).|Graduate School of Life Sciences, Tohoku University, Aoba-ku, Sendai 980-8577, Japan (A.H., Shi.Y.).|RIKEN Center for Sustainable Resource Science, Tsurumi, Yokohama 230-0045, Japan (Sa.Y., K.S.).|Graduate School of Biological Sciences, Nara Institute of Science and Technology, Ikoma, Nara 630-0192, Japan (Sa.Y.).|Department of Agricultural and Environmental Biology, The University of Tokyo, Bunkyo, Tokyo 113-8657 Japan (J.K.).|Bioscience and Biotechnology Center, Nagoya University, Nagoya 464-8601, Japan (M.U.-T., M.M.).|Japan Science and Technology Agency , Core Research for Evolutional Science and Technology (CREST), Kawaguchi-shi, Saitama 332-0012 Japan (T.A.); and.|Department of Biochemistry, King Abdulaziz University, Jeddah 21589, Saudi Arabia (T.A.).
authors.forename: Yasuyuki
authors.initials: Y
authors.lastname: Sasaki
authors.affiliation: Department of Bioscience, Faculty of Applied Bioscience, Tokyo University of Agriculture, Setagaya, Tokyo 156-8502, Japan (S.I., Y.S., Shu.Y.).|Department of Applied Biological Chemistry, The University of Tokyo, Bunkyo, Tokyo 113-8657, Japan (S.I., D.Y., T.A.).|Department of Applied Biosciences, Faculty of Life Sciences, Toyo University, Ora-gun, Gunma 374-0193, Japan (M.U.).|Graduate School of Life Sciences, Tohoku University, Aoba-ku, Sendai 980-8577, Japan (A.H., Shi.Y.).|RIKEN Center for Sustainable Resource Science, Tsurumi, Yokohama 230-0045, Japan (Sa.Y., K.S.).|Graduate School of Biological Sciences, Nara Institute of Science and Technology, Ikoma, Nara 630-0192, Japan (Sa.Y.).|Department of Agricultural and Environmental Biology, The University of Tokyo, Bunkyo, Tokyo 113-8657 Japan (J.K.).|Bioscience and Biotechnology Center, Nagoya University, Nagoya 464-8601, Japan (M.U.-T., M.M.).|Japan Science and Technology Agency , Core Research for Evolutional Science and Technology (CREST), Kawaguchi-shi, Saitama 332-0012 Japan (T.A.); and.|Department of Biochemistry, King Abdulaziz University, Jeddah 21589, Saudi Arabia (T.A.).
authors.forename: Shunsuke
authors.initials: S
authors.lastname: Yajima
authors.affiliation: Department of Bioscience, Faculty of Applied Bioscience, Tokyo University of Agriculture, Setagaya, Tokyo 156-8502, Japan (S.I., Y.S., Shu.Y.).|Department of Applied Biological Chemistry, The University of Tokyo, Bunkyo, Tokyo 113-8657, Japan (S.I., D.Y., T.A.).|Department of Applied Biosciences, Faculty of Life Sciences, Toyo University, Ora-gun, Gunma 374-0193, Japan (M.U.).|Graduate School of Life Sciences, Tohoku University, Aoba-ku, Sendai 980-8577, Japan (A.H., Shi.Y.).|RIKEN Center for Sustainable Resource Science, Tsurumi, Yokohama 230-0045, Japan (Sa.Y., K.S.).|Graduate School of Biological Sciences, Nara Institute of Science and Technology, Ikoma, Nara 630-0192, Japan (Sa.Y.).|Department of Agricultural and Environmental Biology, The University of Tokyo, Bunkyo, Tokyo 113-8657 Japan (J.K.).|Bioscience and Biotechnology Center, Nagoya University, Nagoya 464-8601, Japan (M.U.-T., M.M.).|Japan Science and Technology Agency , Core Research for Evolutional Science and Technology (CREST), Kawaguchi-shi, Saitama 332-0012 Japan (T.A.); and.|Department of Biochemistry, King Abdulaziz University, Jeddah 21589, Saudi Arabia (T.A.).
authors.forename: Junko
authors.initials: J
authors.lastname: Kyozuka
authors.affiliation: Department of Bioscience, Faculty of Applied Bioscience, Tokyo University of Agriculture, Setagaya, Tokyo 156-8502, Japan (S.I., Y.S., Shu.Y.).|Department of Applied Biological Chemistry, The University of Tokyo, Bunkyo, Tokyo 113-8657, Japan (S.I., D.Y., T.A.).|Department of Applied Biosciences, Faculty of Life Sciences, Toyo University, Ora-gun, Gunma 374-0193, Japan (M.U.).|Graduate School of Life Sciences, Tohoku University, Aoba-ku, Sendai 980-8577, Japan (A.H., Shi.Y.).|RIKEN Center for Sustainable Resource Science, Tsurumi, Yokohama 230-0045, Japan (Sa.Y., K.S.).|Graduate School of Biological Sciences, Nara Institute of Science and Technology, Ikoma, Nara 630-0192, Japan (Sa.Y.).|Department of Agricultural and Environmental Biology, The University of Tokyo, Bunkyo, Tokyo 113-8657 Japan (J.K.).|Bioscience and Biotechnology Center, Nagoya University, Nagoya 464-8601, Japan (M.U.-T., M.M.).|Japan Science and Technology Agency , Core Research for Evolutional Science and Technology (CREST), Kawaguchi-shi, Saitama 332-0012 Japan (T.A.); and.|Department of Biochemistry, King Abdulaziz University, Jeddah 21589, Saudi Arabia (T.A.).
authors.forename: Miyako
authors.initials: M
authors.lastname: Ueguchi-Tanaka
authors.affiliation: Department of Bioscience, Faculty of Applied Bioscience, Tokyo University of Agriculture, Setagaya, Tokyo 156-8502, Japan (S.I., Y.S., Shu.Y.).|Department of Applied Biological Chemistry, The University of Tokyo, Bunkyo, Tokyo 113-8657, Japan (S.I., D.Y., T.A.).|Department of Applied Biosciences, Faculty of Life Sciences, Toyo University, Ora-gun, Gunma 374-0193, Japan (M.U.).|Graduate School of Life Sciences, Tohoku University, Aoba-ku, Sendai 980-8577, Japan (A.H., Shi.Y.).|RIKEN Center for Sustainable Resource Science, Tsurumi, Yokohama 230-0045, Japan (Sa.Y., K.S.).|Graduate School of Biological Sciences, Nara Institute of Science and Technology, Ikoma, Nara 630-0192, Japan (Sa.Y.).|Department of Agricultural and Environmental Biology, The University of Tokyo, Bunkyo, Tokyo 113-8657 Japan (J.K.).|Bioscience and Biotechnology Center, Nagoya University, Nagoya 464-8601, Japan (M.U.-T., M.M.).|Japan Science and Technology Agency , Core Research for Evolutional Science and Technology (CREST), Kawaguchi-shi, Saitama 332-0012 Japan (T.A.); and.|Department of Biochemistry, King Abdulaziz University, Jeddah 21589, Saudi Arabia (T.A.).
authors.forename: Makoto
authors.initials: M
authors.lastname: Matsuoka
authors.affiliation: Department of Bioscience, Faculty of Applied Bioscience, Tokyo University of Agriculture, Setagaya, Tokyo 156-8502, Japan (S.I., Y.S., Shu.Y.).|Department of Applied Biological Chemistry, The University of Tokyo, Bunkyo, Tokyo 113-8657, Japan (S.I., D.Y., T.A.).|Department of Applied Biosciences, Faculty of Life Sciences, Toyo University, Ora-gun, Gunma 374-0193, Japan (M.U.).|Graduate School of Life Sciences, Tohoku University, Aoba-ku, Sendai 980-8577, Japan (A.H., Shi.Y.).|RIKEN Center for Sustainable Resource Science, Tsurumi, Yokohama 230-0045, Japan (Sa.Y., K.S.).|Graduate School of Biological Sciences, Nara Institute of Science and Technology, Ikoma, Nara 630-0192, Japan (Sa.Y.).|Department of Agricultural and Environmental Biology, The University of Tokyo, Bunkyo, Tokyo 113-8657 Japan (J.K.).|Bioscience and Biotechnology Center, Nagoya University, Nagoya 464-8601, Japan (M.U.-T., M.M.).|Japan Science and Technology Agency , Core Research for Evolutional Science and Technology (CREST), Kawaguchi-shi, Saitama 332-0012 Japan (T.A.); and.|Department of Biochemistry, King Abdulaziz University, Jeddah 21589, Saudi Arabia (T.A.).
authors.forename: Ken
authors.identifier: http://orcid.org/0000-0002-0349-3870
authors.initials: K
authors.lastname: Shirasu
authors.affiliation: Department of Bioscience, Faculty of Applied Bioscience, Tokyo University of Agriculture, Setagaya, Tokyo 156-8502, Japan (S.I., Y.S., Shu.Y.).|Department of Applied Biological Chemistry, The University of Tokyo, Bunkyo, Tokyo 113-8657, Japan (S.I., D.Y., T.A.).|Department of Applied Biosciences, Faculty of Life Sciences, Toyo University, Ora-gun, Gunma 374-0193, Japan (M.U.).|Graduate School of Life Sciences, Tohoku University, Aoba-ku, Sendai 980-8577, Japan (A.H., Shi.Y.).|RIKEN Center for Sustainable Resource Science, Tsurumi, Yokohama 230-0045, Japan (Sa.Y., K.S.).|Graduate School of Biological Sciences, Nara Institute of Science and Technology, Ikoma, Nara 630-0192, Japan (Sa.Y.).|Department of Agricultural and Environmental Biology, The University of Tokyo, Bunkyo, Tokyo 113-8657 Japan (J.K.).|Bioscience and Biotechnology Center, Nagoya University, Nagoya 464-8601, Japan (M.U.-T., M.M.).|Japan Science and Technology Agency , Core Research for Evolutional Science and Technology (CREST), Kawaguchi-shi, Saitama 332-0012 Japan (T.A.); and.|Department of Biochemistry, King Abdulaziz University, Jeddah 21589, Saudi Arabia (T.A.).
authors.forename: Shinjiro
authors.initials: S
authors.lastname: Yamaguchi
authors.affiliation: Department of Bioscience, Faculty of Applied Bioscience, Tokyo University of Agriculture, Setagaya, Tokyo 156-8502, Japan (S.I., Y.S., Shu.Y.); asami@mail.ecc.u-tokyo.ac.jp.|Department of Applied Biological Chemistry, The University of Tokyo, Bunkyo, Tokyo 113-8657, Japan (S.I., D.Y., T.A.); asami@mail.ecc.u-tokyo.ac.jp.|Department of Applied Biosciences, Faculty of Life Sciences, Toyo University, Ora-gun, Gunma 374-0193, Japan (M.U.); asami@mail.ecc.u-tokyo.ac.jp.|Graduate School of Life Sciences, Tohoku University, Aoba-ku, Sendai 980-8577, Japan (A.H., Shi.Y.); asami@mail.ecc.u-tokyo.ac.jp.|RIKEN Center for Sustainable Resource Science, Tsurumi, Yokohama 230-0045, Japan (Sa.Y., K.S.); asami@mail.ecc.u-tokyo.ac.jp.|Graduate School of Biological Sciences, Nara Institute of Science and Technology, Ikoma, Nara 630-0192, Japan (Sa.Y.); asami@mail.ecc.u-tokyo.ac.jp.|Department of Agricultural and Environmental Biology, The University of Tokyo, Bunkyo, Tokyo 113-8657 Japan (J.K.); asami@mail.ecc.u-tokyo.ac.jp.|Bioscience and Biotechnology Center, Nagoya University, Nagoya 464-8601, Japan (M.U.-T., M.M.); asami@mail.ecc.u-tokyo.ac.jp.|Japan Science and Technology Agency , Core Research for Evolutional Science and Technology (CREST), Kawaguchi-shi, Saitama 332-0012 Japan (T.A.); and asami@mail.ecc.u-tokyo.ac.jp.|Department of Biochemistry, King Abdulaziz University, Jeddah 21589, Saudi Arabia (T.A.) asami@mail.ecc.u-tokyo.ac.jp.
authors.forename: Tadao
authors.identifier: http://orcid.org/0000-0003-0774-6203
authors.initials: T
authors.lastname: Asami
mesh_terms: D017343:Genes, Plant; D018525:Germination / Q000187:drug effects; D005875:Gibberellins / Q000378:metabolism*; D007783:Lactones / Q000378:metabolism*; D009154:Mutation / Q000235:genetics; D012275:Oryza / Q000235:genetics / Q000378:metabolism / Q000469:parasitology; D010935:Plant Diseases / Q000469:parasitology; D010940:Plant Proteins / Q000378:metabolism; D018517:Plant Roots / Q000235:genetics / Q000469:parasitology; D012333:RNA, Messenger / Q000235:genetics / Q000378:metabolism; D015398:Signal Transduction / Q000187:drug effects; D034362:Striga / Q000502:physiology
chemical_list: D005875:Gibberellins; D007783:Lactones; D010940:Plant Proteins; D012333:RNA, Messenger