title: [Atypical presentation of a breast cancer pituitary metastasis].
abstract: Pituitary metastasis occur in 1-5 % of patients with cancer. We report the discovery of a unique pituitary metastasis of breast cancer. A 67 years old woman was treated in 2003 for local adenocarcinoma. After bone metastatic relapse in 2008, the patient developed diplopia and diabetes insipidus. An MRI revealed a histologically proven metastatic pituitary nodule. Further explorations revealed failure of multiple endocrine axes. Pituitary metastases are relatively rare, but are probably under-diagnosed in the presence of advanced cancers with impaired general condition. This diagnosis should be considered in the context of cancer patients, with a recent history of diabetes insipidus, especially if the latter is associated with other neurological signs (ophthalmoplegia, cephallagia).
authors.affiliation: Département de Radiothérapie, Institut de Cancérologie Lucien Neuwirth, Saint Priest en Jarez, 42271 France.
authors.forename: J
authors.initials: J
authors.lastname: Langrand-Escure
authors.affiliation: Département de Radiothérapie, Centre Hospitalier de Roanne, 42300 France.
authors.forename: A
authors.initials: A
authors.lastname: Vallard
authors.affiliation: Département de Radiothérapie, Institut de Cancérologie Lucien Neuwirth, Saint Priest en Jarez, 42271 France.
authors.forename: J-Ph
authors.initials: JP
authors.lastname: Suchaud
authors.affiliation: Département de Radiothérapie, Institut de Cancérologie Lucien Neuwirth, Saint Priest en Jarez, 42271 France.
authors.forename: P
authors.initials: P
authors.lastname: Diao
authors.affiliation: Département de Radiothérapie, Institut de Cancérologie Lucien Neuwirth, Saint Priest en Jarez, 42271 France.
authors.forename: N
authors.initials: N
authors.lastname: Magné
mesh_terms: D000230:Adenocarcinoma / Q000150:complications / Q000175:diagnosis / Q000556:secondary*; D000368:Aged; D001943:Breast Neoplasms / Q000150:complications / Q000473:pathology*; D003919:Diabetes Insipidus / Q000175:diagnosis* / Q000209:etiology; D003937:Diagnosis, Differential; D004172:Diplopia / Q000175:diagnosis / Q000209:etiology; D005260:Female; D006801:Humans; D010911:Pituitary Neoplasms / Q000150:complications / Q000175:diagnosis / Q000556:secondary*
keywords:  Diabetes insipidus;  Metastasis ;  Pituitary gland ; Keywords : Breast cancer 