title: Iris reconstruction using autologous iris preserved in cold balanced salt solution for 8 hours in iatrogenic total iridodialysis during cataract surgery: a case report.
abstract: BACKGROUND
  A large iris defect or extensive iridodialysis can be an intractable cause of visual disturbance, photophobia, glare, monocular diplopia, or cosmetic deformity. The implantation of an artificial iris substitute could be an effective option, but this can cause a reduction in endothelial cell density. We succeeded in the anatomical restoration of iris tissue that was totally dialyzed out of the eye, and was preserved in cold balanced salt solution for 8 h. Engrafted iris tissue was maintained within the aqueous humor.
  
  
  METHODS
  A 71-year-old man was referred to our clinic for management of an iatrogenic total iridodialysis. The totally dialyzed iris tissue was immediately preserved in sterile cold balanced salt solution and packed in a sterile biopsy bottle that was surrounded with ice cubes. Under general anesthesia, a pars plana vitrectomy was performed to remove the remaining lens cortex and vitreous fiber anterior to the equator. A sulcus-positioned intraocular lens (IOL) was repositioned and fixed by ab externo scleral sutures. Preserved iris tissue was inserted and ironed using both iris spatula and ocular viscoelastic devices. Five-point ab interno scleral sutures were made 1.0 mm posterior to the limbus.
  
  
  CONCLUSIONS
  The engrafted iris was successfully maintained for 6 months and did not undergo any atrophic change or depigmentation, which may be caused by primary implantation failure due to a blocked blood supply.
authors.affiliation: Department of Ophthalmology, Keimyung University School of Medicine, #56, Dalseong-ro, Jung-gu, Daegu, 700-712, Korea.
authors.forename: Seung Pil
authors.initials: SP
authors.lastname: Bang
authors.affiliation: Department of Ophthalmology, Keimyung University School of Medicine, #56, Dalseong-ro, Jung-gu, Daegu, 700-712, Korea. junjonghwa@gmail.com.
authors.forename: Jong Hwa
authors.initials: JH
authors.lastname: Jun
mesh_terms: D000368:Aged; D002387:Cataract Extraction / Q000009:adverse effects*; D003080:Cold Temperature; D005500:Follow-Up Studies; D006801:Humans; D007049:Iatrogenic Disease; D007431:Intraoperative Complications; D007498:Iris / Q000293:injuries / Q000637:transplantation*; D007499:Iris Diseases / Q000209:etiology / Q000601:surgery*; D008297:Male; D013508:Ophthalmologic Surgical Procedures / Q000379:methods; D019188:Organ Preservation Solutions / Q000494:pharmacology; D019651:Plastic Surgery Procedures / Q000379:methods*; D012965:Sodium Chloride / Q000494:pharmacology*; D013997:Time Factors; D014021:Tissue Preservation / Q000379:methods*; D014182:Transplantation, Autologous
chemical_list: D019188:Organ Preservation Solutions; D012965:Sodium Chloride
keywords: Balanced salt solution; Iatrogenic; Iris reconstruction; Total iridodialysis