title: Advances in Skin Regeneration Using Tissue Engineering.
abstract: Tissue engineered skin substitutes for wound healing have evolved tremendously over the last couple of years. New advances have been made toward developing skin substitutes made up of artificial and natural materials. Engineered skin substitutes are developed from acellular materials or can be synthesized from autologous, allograft, xenogenic, or synthetic sources. Each of these engineered skin substitutes has their advantages and disadvantages. However, to this date, a complete functional skin substitute is not available, and research is continuing to develop a competent full thickness skin substitute product that can vascularize rapidly. There is also a need to redesign the currently available substitutes to make them user friendly, commercially affordable, and viable with longer shelf life. The present review focuses on providing an overview of advances in the field of tissue engineered skin substitute development, the availability of various types, and their application.
authors.affiliation: Center for Nanobiotechnology Research, Alabama State University, 1627 Harris Way, Montgomery, AL 36104, USA. komalvig@alasu.edu.
authors.forename: Komal
authors.initials: K
authors.lastname: Vig
authors.affiliation: Center for Nanobiotechnology Research, Alabama State University, 1627 Harris Way, Montgomery, AL 36104, USA. achaudhari@alasu.edu.
authors.forename: Atul
authors.initials: A
authors.lastname: Chaudhari
authors.affiliation: Center for Nanobiotechnology Research, Alabama State University, 1627 Harris Way, Montgomery, AL 36104, USA. tripshweta@gmail.com.
authors.forename: Shweta
authors.initials: S
authors.lastname: Tripathi
authors.affiliation: Center for Nanobiotechnology Research, Alabama State University, 1627 Harris Way, Montgomery, AL 36104, USA. sdixit@alasu.edu.
authors.forename: Saurabh
authors.initials: S
authors.lastname: Dixit
authors.affiliation: Center for Nanobiotechnology Research, Alabama State University, 1627 Harris Way, Montgomery, AL 36104, USA. sahu.rajnish@gmail.com.
authors.forename: Rajnish
authors.initials: R
authors.lastname: Sahu
authors.affiliation: Center for Nanobiotechnology Research, Alabama State University, 1627 Harris Way, Montgomery, AL 36104, USA. spillai@alasu.edu.
authors.forename: Shreekumar
authors.initials: S
authors.lastname: Pillai
authors.affiliation: Center for Nanobiotechnology Research, Alabama State University, 1627 Harris Way, Montgomery, AL 36104, USA. vdennis@alasu.edu.
authors.forename: Vida A
authors.initials: VA
authors.lastname: Dennis
authors.affiliation: Center for Nanobiotechnology Research, Alabama State University, 1627 Harris Way, Montgomery, AL 36104, USA. ssingh@alasu.edu.
authors.forename: Shree R
authors.initials: SR
authors.lastname: Singh
mesh_terms: D001672:Biocompatible Materials; D006801:Humans; D012038:Regeneration; D012879:Skin Physiological Phenomena; D016038:Skin Transplantation; D017768:Skin, Artificial; D023822:Tissue Engineering / Q000379:methods*; D014945:Wound Healing
chemical_list: D001672:Biocompatible Materials
keywords: skin regeneration; skin substitutes; tissue engineering