title: Potential Use of Cyclodextrins as Drug Carriers and Active Pharmaceutical Ingredients.
abstract: Cyclodextrins (CyDs) are extensively used in various fields, and especially have been widely utilized as pharmaceutical excipients and drug carriers in the pharmaceutical field. Owing to the multi-functional and biocompatible characteristics, CyDs can improve the undesirable properties of drug molecules. This review outlines the current application of CyDs in pharmaceutical formulations, focusing on their use as CyD-based drug carriers for several kinds of drugs. Additionally, CyDs have great potential as active pharmaceutical ingredients against various diseases with few side effects.
authors.affiliation: Graduate School of Pharmaceutical Sciences, Kumamoto University.
authors.forename: Hidetoshi
authors.initials: H
authors.lastname: Arima
authors.forename: Keiichi
authors.initials: K
authors.lastname: Motoyama
authors.forename: Taishi
authors.initials: T
authors.lastname: Higashi
mesh_terms: D000818:Animals; D003505:Cyclodextrins / Q000009:adverse effects / Q000737:chemistry*; D004194:Disease; D004337:Drug Carriers / Q000009:adverse effects / Q000737:chemistry*; D006801:Humans; D015394:Molecular Structure; D004364:Pharmaceutical Preparations / Q000737:chemistry*
chemical_list: D003505:Cyclodextrins; D004337:Drug Carriers; D004364:Pharmaceutical Preparations