title: Structuring supplemental materials in support of reproducibility.
abstract: Supplements are increasingly important to the scientific record, particularly in genomics. However, they are often underutilized. Optimally, supplements should make results findable, accessible, interoperable, and reusable (i.e., "FAIR"). Moreover, properly off-loading to them the data and detail in a paper could make the main text more readable. We propose a hierarchical organization for supplements, with some parts paralleling and "shadowing" the main text and other elements branching off from it, and we suggest a specific formatting to make this structure explicit. Furthermore, sections of the supplement could be presented in multiple scientific "dialects", including machine-readable and lay-friendly formats.
authors.affiliation: Zvi Meitar Institute for Legal Implications of Emerging Technologies, Radzyner Law School, Interdisciplinary Center, Herzliya, Israel.|Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, 06520, USA.
authors.forename: Dov
authors.initials: D
authors.lastname: Greenbaum
authors.affiliation: Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, 06520, USA.|Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, 06520, USA.
authors.forename: Joel
authors.initials: J
authors.lastname: Rozowsky
authors.affiliation: Graduate School of Library and Information Science, University of Illinois at Urbana-Champaign, 501 E Daniel St, Champaign, IL, 61820, USA.
authors.forename: Victoria
authors.initials: V
authors.lastname: Stodden
authors.affiliation: Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, 06520, USA. mark@gersteinlab.org.|Integrated Graduate Program in Physical and Engineering Biology, Yale University, New Haven, CT, 06520, USA. mark@gersteinlab.org.|Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, 06520, USA. mark@gersteinlab.org.|Department of Computer Science, Yale University, New Haven, CT, 06520, USA. mark@gersteinlab.org.
authors.forename: Mark
authors.initials: M
authors.lastname: Gerstein
mesh_terms: D003626:Data Display / Q000592:standards*; D023281:Genomics; D006801:Humans; D011642:Publications / Q000592:standards*; D015203:Reproducibility of Results