title: Carotid-Femoral Pulse Wave Velocity Assessed by Ultrasound: A Study with Echotracking Technology.
abstract: Described here is a new method for determination of carotid-femoral pulse wave velocity (PWV) based on arterial diameter waveform recording by an ultrasound system. The study was carried out on 120 consecutive patients. Carotid-femoral PWV was determined using a tonometric technique (PWVpp, PulsePen, DiaTecne, Milan, Italy) and an echotracking ultrasound system (PWVet, E-Track, Aloka, Tokyo, Japan). The relationship between PWVpp and PWVet was evaluated by linear regression and Bland-Altman analysis. There was excellent agreement between PWVet and PWVpp (Pearson's r = 0.94, 95% confidence interval: 0.91-0.96, p < 0.0001; PWVet = 0.88 × PWVpp + 0.57). The Bland-Altman plot revealed an offset of -0.33 m/s with limits of agreement from -2.21 to 1.54 m/s. The coefficients of variation for within-subject repeatability between PWVet and PWVpp had were 5.79% and 8.47%, respectively, without significant differences in the Bland-Altman analysis. The results suggest that echotracking technology can provide a reliable estimate of aortic stiffness comparable to that of the tonometric techniques.
authors.affiliation: Groupe ESAIP, Saint Barthélemy d'Anjou, France; Laboratoire Angevin de Recherche en Ingénierie des Systèmes (LARIS), Université d'Angers, Angers, France. Electronic address: mcollette@esaip.org.
authors.forename: Mathieu
authors.initials: M
authors.lastname: Collette
authors.affiliation: Department of Surgical, Medical, Molecular Pathology and Critical Care Medicine, University of Pisa, Pisa, Italy.
authors.forename: Carlo
authors.initials: C
authors.lastname: Palombo
authors.affiliation: Department of Surgical, Medical, Molecular Pathology and Critical Care Medicine, University of Pisa, Pisa, Italy.
authors.forename: Carmela
authors.initials: C
authors.lastname: Morizzo
authors.affiliation: Department of Surgical, Medical, Molecular Pathology and Critical Care Medicine, University of Pisa, Pisa, Italy.
authors.forename: Sara
authors.initials: S
authors.lastname: Sbragi
authors.affiliation: Department of Surgical, Medical, Molecular Pathology and Critical Care Medicine, University of Pisa, Pisa, Italy.
authors.forename: Michaela
authors.initials: M
authors.lastname: Kozakova
authors.affiliation: Faculté de Médecine, Université de Nice, LP2M-CNRS-UNS UMR 7370, Nice, France; Unité d'Explorations Fonctionnelles Vasculaires, Nice, France.
authors.forename: Georges
authors.initials: G
authors.lastname: Leftheriotis
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001795:Blood Pressure Determination / Q000379:methods; D002339:Carotid Arteries / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D004452:Echocardiography / Q000379:methods*; D005260:Female; D005263:Femoral Artery / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D005602:France; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D007090:Image Interpretation, Computer-Assisted / Q000379:methods; D007558:Italy; D008297:Male; D008875:Middle Aged; D063177:Pulse Wave Analysis / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D059289:Vascular Stiffness; D055815:Young Adult
keywords: Applanation tonometry; Arterial stiffness; Echo-tracking; Ultrasound