title: Recent insight into potential acute respiratory distress syndrome.
abstract: Acute respiratory distress syndrome (ARDS) is an acute inflammatory lung injury, characterized by increased pulmonary capillary endothelial cells and alveolar epithelial cells permeability leading to respiratory failure in the absence of cardiac failure. Despite recent advances in treatments, the overall mortality because of ARDS remains high. Biomarkers may help to diagnose, predict the severity, development, and outcome of ARDS in order to improve patient care and decrease morbidity and mortality. This review will focus on soluble receptor for advanced glycation end-products, soluble tumor necrosis factor-receptor 1, Interluken-6 (IL-6), IL-8, and plasminogen activator inhibitor-1, which have a greater potential based on recent studies.
authors.affiliation: Internal Medicine Department, Faculty of Medicine, University of Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia. E-mail. zulkifliamin52@gmail.com.
authors.forename: Zulkifli
authors.initials: Z
authors.lastname: Amin
authors.forename: Fitriana N
authors.initials: FN
authors.lastname: Rahmawati
mesh_terms: D055371:Acute Lung Injury / Q000175:diagnosis*; D056809:Alveolar Epithelial Cells / Q000378:metabolism; D015415:Biomarkers / Q000378:metabolism; D006801:Humans; D015850:Interleukin-6 / Q000378:metabolism; D016209:Interleukin-8 / Q000378:metabolism; D017395:Plasminogen Activator Inhibitor 1 / Q000378:metabolism; D000067759:Receptor for Advanced Glycation End Products / Q000378:metabolism; D047888:Receptors, Tumor Necrosis Factor, Type I / Q000378:metabolism; D012128:Respiratory Distress Syndrome / Q000175:diagnosis*
chemical_list: D015415:Biomarkers; D015850:Interleukin-6; D016209:Interleukin-8; D017395:Plasminogen Activator Inhibitor 1; D000067759:Receptor for Advanced Glycation End Products; D047888:Receptors, Tumor Necrosis Factor, Type I; C051321:SERPINE1 protein, human