title: Combined use of laser Doppler flowmetry and skin thermometry for functional diagnostics of intradermal finger vessels.
abstract: We introduce a noninvasive diagnostic approach for functional monitoring of blood microflows in capillaries and thermoregulatory vessels within the skin. The measuring system is based on the combined use of laser Doppler flowmetry and skin contact thermometry. The obtained results suggest that monitoring of blood microcirculation during the occlusion, performed in conjunction with the skin temperature measurements in the thermally stabilized medium, has a great potential for quantitative assessment of angiospatic dysfunctions of the peripheral blood vessels. The indices of blood flow reserve and temperature response were measured and used as the primarily parameters of the functional diagnostics of the peripheral vessels of skin. Utilizing these parameters, a simple phenomenological model has been suggested to identify patients with angiospastic violations in the vascular system.
authors.affiliation: Orel State University, Scientific-Educational Centre of Biomedical Engineering, Biomedical Photonics Instrumentation Group, Orel, RussiabUniversity of Oulu, ITEE, Optoelectronics and Measurement Techniques Unit, Oulu, Finland.
authors.forename: Evgeny A
authors.initials: EA
authors.lastname: Zherebtsov
authors.affiliation: Orel State University, Scientific-Educational Centre of Biomedical Engineering, Biomedical Photonics Instrumentation Group, Orel, Russia.
authors.forename: Angelina I
authors.initials: AI
authors.lastname: Zherebtsova
authors.affiliation: Yale University, Department of Computer Science, Computer Graphics Group, New Haven, Connecticut, United States.
authors.forename: Alexander
authors.initials: A
authors.lastname: Doronin
authors.affiliation: Orel State University, Scientific-Educational Centre of Biomedical Engineering, Biomedical Photonics Instrumentation Group, Orel, Russia.
authors.forename: Andrey V
authors.initials: AV
authors.lastname: Dunaev
authors.affiliation: Orel State University, Scientific-Educational Centre of Biomedical Engineering, Biomedical Photonics Instrumentation Group, Orel, Russia.
authors.forename: Konstantin V
authors.initials: KV
authors.lastname: Podmasteryev
authors.affiliation: University of Oulu, ITEE, Optoelectronics and Measurement Techniques Unit, Oulu, FinlanddTomsk State University, Interdisciplinary Laboratory of Biophotonics, Tomsk, RussiaeITMO University, Saint-Petersburg, Russia.
authors.forename: Alexander
authors.initials: A
authors.lastname: Bykov
authors.affiliation: University of Oulu, ITEE, Optoelectronics and Measurement Techniques Unit, Oulu, FinlanddTomsk State University, Interdisciplinary Laboratory of Biophotonics, Tomsk, RussiaeITMO University, Saint-Petersburg, RussiafIrkutsk State University, Institute of Biology, Irkutsk, Russia.
authors.forename: Igor
authors.initials: I
authors.lastname: Meglinski
mesh_terms: D005385:Fingers / Q000098:blood supply; D006801:Humans; D017078:Laser-Doppler Flowmetry; D008833:Microcirculation; D012867:Skin / Q000098:blood supply; D012881:Skin Temperature; D062125:Thermometry