title: Photoredox-catalyzed oxytrifluoromethylation of allenes: stereoselective synthesis of 2-trifluoromethylated allyl acetates.
abstract: We have developed novel oxytrifluoromethylation of aryl-substituted allenes by photoredox catalysis. The present photocatalytic system allows direct and stereoselective synthesis of 2-CF3-allyl acetates bearing tetrasubstituted CF3-alkene scaffolds in a single operation. The obtained CF3-allyl acetates can be applied to further functionalization as CF3-containing building blocks.
authors.affiliation: Laboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology, R1-27, 4259 Nagatsuta-cho, Midori-ku, Yokohama, 226-8503, Japan. koike.t.ad@m.titech.ac.jp makita@res.titech.ac.jp.
authors.forename: Ren
authors.initials: R
authors.lastname: Tomita
authors.forename: Takashi
authors.initials: T
authors.lastname: Koike
authors.forename: Munetaka
authors.initials: M
authors.lastname: Akita