title: Seeing SPIOs Directly In Vivo with Magnetic Particle Imaging.
abstract: Magnetic particle imaging (MPI) is a new molecular imaging technique that directly images superparamagnetic tracers with high image contrast and sensitivity approaching nuclear medicine techniques-but without ionizing radiation. Since its inception, the MPI research field has quickly progressed in imaging theory, hardware, tracer design, and biomedical applications. Here, we describe the history and field of MPI, outline pressing challenges to MPI technology and clinical translation, highlight unique applications in MPI, and describe the role of the WMIS MPI Interest Group in collaboratively advancing MPI as a molecular imaging technique. We invite interested investigators to join the MPI Interest Group and contribute new insights and innovations to the MPI field.
authors.affiliation: Department of Bioengineering, UC Berkeley, Berkeley, CA, USA. bozheng@berkeley.edu.
authors.forename: Bo
authors.identifier: 0000-0003-0555-9826
authors.initials: B
authors.lastname: Zheng
authors.affiliation: Department of Bioengineering, UC Berkeley, Berkeley, CA, USA.
authors.forename: Elaine
authors.initials: E
authors.lastname: Yu
authors.affiliation: Department of Bioengineering, UC Berkeley, Berkeley, CA, USA.
authors.forename: Ryan
authors.initials: R
authors.lastname: Orendorff
authors.affiliation: Triple Ring Technologies, Newark, CA, USA.
authors.forename: Kuan
authors.initials: K
authors.lastname: Lu
authors.affiliation: Magnetic Insight, Alameda, CA, USA.
authors.forename: Justin J
authors.initials: JJ
authors.lastname: Konkle
authors.affiliation: Department of Bioengineering, UC Berkeley, Berkeley, CA, USA.
authors.forename: Zhi Wei
authors.initials: ZW
authors.lastname: Tay
authors.affiliation: Department of Bioengineering, UC Berkeley, Berkeley, CA, USA.|Magnetic Insight, Alameda, CA, USA.
authors.forename: Daniel
authors.initials: D
authors.lastname: Hensley
authors.affiliation: Department of Bioengineering, UC Berkeley, Berkeley, CA, USA.
authors.forename: Xinyi Y
authors.initials: XY
authors.lastname: Zhou
authors.affiliation: Department of Bioengineering, UC Berkeley, Berkeley, CA, USA.
authors.forename: Prashant
authors.initials: P
authors.lastname: Chandrasekharan
authors.affiliation: Department of Electrical and Electronics Engineering, Bilkent University, Ankara, Turkey.|National Magnetic Resonance Research Center (UMRAM), Bilkent University, Ankara, Turkey.
authors.forename: Emine U
authors.initials: EU
authors.lastname: Saritas
authors.affiliation: Magnetic Insight, Alameda, CA, USA.
authors.forename: Patrick W
authors.initials: PW
authors.lastname: Goodwill
authors.affiliation: Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
authors.forename: John D
authors.initials: JD
authors.lastname: Hazle
authors.affiliation: Department of Bioengineering, UC Berkeley, Berkeley, CA, USA.|Department of Electrical Engineering and Computer Science, UC Berkeley, Berkeley, CA, USA.
authors.forename: Steven M
authors.initials: SM
authors.lastname: Conolly
mesh_terms: D000818:Animals; D003911:Dextrans / Q000737:chemistry*; D006801:Humans; D058185:Magnetite Nanoparticles / Q000737:chemistry*; D057054:Molecular Imaging / Q000379:methods*
chemical_list: D003911:Dextrans; D058185:Magnetite Nanoparticles; C065507:ferumoxides
keywords: Interest group; Magnetic particle imaging; Superparamagnetic iron oxide