title: Fever in Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in Pediatric Cases: Laboratory Work-up and Antibiotic Therapy.
abstract: Fever is a symptom that often accompanies skin eruptions, especially in children. It can be a sign of an infectious condition presenting with exanthems or it may precede an exanthematous eruption. Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are severe reactions affecting skin and mucosa with blisters and erosions. High fever occurs in these conditions, frequently before the skin and/or mucosa is affected.
authors.affiliation: From the Department of Dermatology, Dokumentationszentrum schwerer Hautreaktionen (dZh), Medical Center-University of Freiburg, Hauptstrasse 7, 79104 Freiburg, Germany.
authors.forename: Maren
authors.initials: M
authors.lastname: Paulmann
authors.forename: Maja
authors.initials: M
authors.lastname: Mockenhaupt
mesh_terms: D000293:Adolescent; D000700:Analgesics / Q000009:adverse effects; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D058633:Antipyretics / Q000009:adverse effects; D001424:Bacterial Infections / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology; D001768:Blister / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology / Q000473:pathology; D002648:Child; D003937:Diagnosis, Differential; D004892:Erythema Multiforme / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology / Q000473:pathology; D005260:Female; D005334:Fever / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology / Q000473:pathology; D006801:Humans; D008297:Male; D009092:Mucous Membrane / Q000473:pathology; D012867:Skin / Q000473:pathology; D013262:Stevens-Johnson Syndrome / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology / Q000473:pathology; D014777:Virus Diseases / Q000150:complications / Q000175:diagnosis / Q000473:pathology
chemical_list: D000700:Analgesics; D000900:Anti-Bacterial Agents; D058633:Antipyretics