title: Endocrine Gland-Derived Vascular Endothelial Growth Factor/Prokineticin-1 in Cancer Development and Tumor Angiogenesis.
abstract: A lot of data suggests endocrine gland-derived vascular endothelial growth factor (EG-VEGF) to be restricted to endocrine glands and to some endocrine-dependent organs. Many evidences show that EG-VEGF stimulates angiogenesis and cell proliferation, although it is not a member of the VEGF family. At the time, a lot of data regarding the role of this growth factor in normal development are available. However, controversial results have been published in the case of pathological conditions and particularly in malignant tumors. Thus, our present paper has been focused on the role of EG-VEGF in normal tissues and various malignant tumors and their angiogenic processes.
authors.affiliation: Department of Endocrinology, "Vasile Goldis" University of Arad, Arad, Romania.
authors.forename: Ana Silvia
authors.initials: AS
authors.lastname: Corlan
authors.affiliation: Department of Microscopic Morphology/Histology, Angiogenesis Research Center, "Victor Babeș" University of Medicine and Pharmacy Timișoara, Timișoara, Romania.
authors.forename: Anca Maria
authors.identifier: 0000-0002-9530-022X
authors.initials: AM
authors.lastname: Cîmpean
authors.affiliation: Department of Microscopic Morphology/Histology, Angiogenesis Research Center, "Victor Babeș" University of Medicine and Pharmacy Timișoara, Timișoara, Romania.
authors.forename: Adriana-Andreea
authors.initials: AA
authors.lastname: Jitariu
authors.affiliation: Department of Pathology, "Nicolae Testemitanu" University of Medicine and Pharmacy, Chișinău, Moldova.
authors.forename: Eugen
authors.initials: E
authors.lastname: Melnic
authors.affiliation: Department of Microscopic Morphology/Histology, Angiogenesis Research Center, "Victor Babeș" University of Medicine and Pharmacy Timișoara, Timișoara, Romania.
authors.forename: Marius
authors.initials: M
authors.lastname: Raica