title: Dynamic contrast-enhanced MR imaging in osteoid osteoma: relationships with clinical and CT characteristics.
abstract: OBJECTIVE
  To correlate dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) features to clinical and computed tomography (CT) morphological features of osteoid osteoma (OO).
  
  
  METHODS
  Our institutional review board approved this retrospective study, waiving the need for informed consent. We included the 102 patients treated with interstitial laser ablation for histologically documented OO at our institution in 2008-2013. DCE-MRI variables were the time-enhancement pattern and rising slope (Sloperise) and CT variables were the bone and segment involved (OOboneand OOsegment,respectively), OO location relative to the native cortex (OOcortex), nidus surface area, vessel sign, and largest neighboring-vessel diameter (Dmaxvessel). Descriptive statistics and correlations linking DCE-MRI findings to clinical and CT characteristics were computed.
  
  
  RESULTS
  DCE-MRI showed early arterial peak enhancement in 95 (93%) cases, with a mean Sloperiseof 9.30 ± 8.10. CT visualized a vessel sign in 84 (82%) cases with a mean Dmaxvesselof 1.10 ± 0.60 mm. By univariate analysis, Sloperisecorrelated significantly with pain duration and Dmaxvessel(r = 0.30, P = 0.003; and r = 0.22, P = 0.03; respectively). Analysis of variance showed that Sloperisecorrelated significantly with OObone(P < 0.001), with a steeper slope for OOs located in short or flat bones.
  
  
  CONCLUSIONS
  This study suggests more abundant vascularization of OOs with long-lasting pain and location on short or flat bones.
authors.affiliation: Department of Osteoarticular Radiology, Hôpital Lariboisière, AP-HP, 2 rue Ambroise Paré, 75475, Paris Cedex 10, France. pierre.pottecher@gmail.com.|Department of Vascular, Oncologic and Interventional Radiology, Hôpital du Bocage, 14, rue Paul-Gaffarel, BP 77908, 21079, Dijon cedex, France. pierre.pottecher@gmail.com.
authors.forename: P
authors.initials: P
authors.lastname: Pottecher
authors.affiliation: Department of Osteoarticular Radiology, Hôpital Lariboisière, AP-HP, 2 rue Ambroise Paré, 75475, Paris Cedex 10, France.
authors.forename: E
authors.initials: E
authors.lastname: Sibileau
authors.affiliation: Hospital Hygiene and Epidemiology unit, Hôpital du Bocage, BP 77908, 21079, Dijon Cedex, France.
authors.forename: S
authors.initials: S
authors.lastname: Aho
authors.affiliation: Department of Osteoarticular Radiology, Hôpital Lariboisière, AP-HP, 2 rue Ambroise Paré, 75475, Paris Cedex 10, France.
authors.forename: B
authors.initials: B
authors.lastname: Hamze
authors.affiliation: Department of Osteoarticular Radiology, Hôpital Lariboisière, AP-HP, 2 rue Ambroise Paré, 75475, Paris Cedex 10, France.
authors.forename: C
authors.initials: C
authors.lastname: Parlier
authors.affiliation: Department of Osteoarticular Radiology, Hôpital Lariboisière, AP-HP, 2 rue Ambroise Paré, 75475, Paris Cedex 10, France.
authors.forename: J D
authors.initials: JD
authors.lastname: Laredo
authors.affiliation: Department of Osteoarticular Radiology, Hôpital Lariboisière, AP-HP, 2 rue Ambroise Paré, 75475, Paris Cedex 10, France.
authors.forename: V
authors.initials: V
authors.lastname: Bousson
mesh_terms: D000293:Adolescent; D000328:Adult; D001859:Bone Neoplasms / Q000000981:diagnostic imaging*; D002648:Child; D003287:Contrast Media; D005260:Female; D006801:Humans; D007090:Image Interpretation, Computer-Assisted; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D010017:Osteoma, Osteoid / Q000000981:diagnostic imaging*; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed / Q000379:methods*
chemical_list: D003287:Contrast Media
keywords: Dynamic contrast-enhanced MRI; Osteoid osteoma; Pain; Vascular groove sign; Vessel sign