title: [Light protection for xeroderma pigmentosum].
abstract: Xeroderma pigmentosum is a rare autosomal recessive disorder which is caused by germinal mutations responsible for the repair of ultraviolet (UV) radiation-induced DNA lesions. It is characterized by hypersensitivity to UV radiation, poikiloderma, ocular surface disease, and in some patients pronounced sunburn and neurological disease. Patients have a very high risk of developing ocular and skin cancer on exposed body sites. No cure is available for these patients except complete protection from all types of UV radiation.
authors.affiliation: Universitätsklinik für Dermatologie, Franz-Josef-Strauß Allee 11, 93053, Regensburg, Deutschland.
authors.forename: M
authors.initials: M
authors.lastname: Ettinger
authors.affiliation: Universitätsklinik für Dermatologie, Franz-Josef-Strauß Allee 11, 93053, Regensburg, Deutschland. mark.berneburg@ukr.de.
authors.forename: M
authors.initials: M
authors.lastname: Berneburg
mesh_terms: D000975:Antioxidants / Q000008:administration & dosage* / Q000737:chemistry; D003880:Dermatology / Q000639:trends; D019317:Evidence-Based Medicine; D006801:Humans; D011835:Radiation Protection / Q000379:methods*; D011837:Radiation-Protective Agents / Q000008:administration & dosage / Q000737:chemistry; D012993:Solar Energy; D013472:Sunlight / Q000009:adverse effects*; D013473:Sunscreening Agents / Q000008:administration & dosage* / Q000737:chemistry; D016896:Treatment Outcome; D014983:Xeroderma Pigmentosum / Q000209:etiology* / Q000517:prevention & control*
chemical_list: D000975:Antioxidants; D011837:Radiation-Protective Agents; D013473:Sunscreening Agents
keywords: Genodermatosis; Light protection; Light sensitivity; Poikiloderma; Tumors