title: Paratuberculosis in a domestic dog in South Africa.
abstract: This case report shows that Mycobacterium avium subsp. paratuberculosis (MAP) infection can cause clinical disease in domestic dogs, and should be considered as a differential diagnosis for gastrointestinal inflammatory conditions. A male dachshund presented with lethargy and pain. Enlarged mesenteric lymph nodes were found on abdominal ultrasound examination. Cytological examination of lymph node aspirates was consistent with granulomatous inflammation, which was culture-confirmed as MAP. Although we were unable to confirm the source of infection, the dog's history included exposure to sheep in the Western Cape.
authors.affiliation: DST NRF Centre of Excellence for Biomedical Tuberculosis Research, South African Medical Research Council Centre for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Stellenbosch University. miller@sun.ac.za.
authors.forename: Michele A
authors.initials: MA
authors.lastname: Miller
authors.forename: Sewellyn C
authors.initials: SC
authors.lastname: Davey
authors.forename: Lesley S
authors.initials: LS
authors.lastname: Van Helden
authors.forename: Frank
authors.initials: F
authors.lastname: Kettner
authors.forename: Sandy M
authors.initials: SM
authors.lastname: May
authors.forename: Rick
authors.initials: R
authors.lastname: Last
authors.forename: John D
authors.initials: JD
authors.lastname: Grewar
authors.forename: Louise
authors.initials: L
authors.lastname: Botha
authors.forename: Paul D
authors.initials: PD
authors.lastname: Van Helden
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001344:Autopsy / Q000662:veterinary; D003937:Diagnosis, Differential; D004283:Dog Diseases / Q000175:diagnosis / Q000382:microbiology* / Q000473:pathology; D004285:Dogs; D008297:Male; D016927:Mycobacterium avium subsp. paratuberculosis / Q000302:isolation & purification; D010283:Paratuberculosis / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D013019:South Africa
chemical_list: D000900:Anti-Bacterial Agents