title: A combination strategy using two novel cerium-based nanocomposite affinity probes for the selective enrichment of mono- and multi-phosphopeptides in mass spectrometric analysis.
abstract: This work presents a sequential enrichment protocol, based on two self-designed cerium-based nanocomposite affinity probes, which not only can effectively separate phosphopeptides from non-phosphopeptides but can also selectively differentiate mono- and multi-phosphopeptides for direct matrix-assisted laser desorption/ionization time-of-flight mass spectrometric (MALDI-TOF MS) analysis.
authors.affiliation: State Key Laboratory of Analytical Chemistry for Life Science, Collaborative Innovation Center of Chemistry for Life Sciences, School of Chemistry & Chemical Engineering and Center of Materials Analysis, Nanjing University, 163 Xianlin Avenue, Nanjing 210023, P. R. China. hzlian@nju.edu.cn.
authors.forename: Xing-Yu
authors.initials: XY
authors.lastname: Long
authors.forename: Zi-Jin
authors.initials: ZJ
authors.lastname: Zhang
authors.forename: Jia-Yuan
authors.initials: JY
authors.lastname: Li
authors.forename: Dong
authors.initials: D
authors.lastname: Sheng
authors.forename: Hong-Zhen
authors.initials: HZ
authors.lastname: Lian