title: Treatment of recalcitrant erosive oral lichen planus and desquamative gingivitis with oral apremilast.
abstract: BACKGROUND
  Erosive oral lichen planus and desquamative gingivitis are uncommon but severe debilitating variants of oral lichen planus. Treatment of these presentations is difficult and challenging.
  
  
  METHODS
  A 44-year-old woman was referred to the dermatology clinic with chronic painful lichen planus-related gingivitis and buccal erosions. She has failed multiple treatments including topical clobetasol and tacrolimus, intralesional corticosteroids and several systemic and immunosuppressive agents. Following completion of three months of treatment with oral apremilast at a dose of 30 mg twice daily, significant improvement was noted in her disease activity.
  
  
  CONCLUSIONS
  Oral apremilast may be a safe and effective treatment for erosive oral lichen planus.
authors.affiliation: Division of Dermatology, Department of Medicine, Sunnybrook Health Sciences Center and University of Toronto, Toronto, Canada.
authors.forename: Mohn'd
authors.initials: M
authors.lastname: AbuHilal
authors.affiliation: Division of Dermatology, Department of Medicine, Sunnybrook Health Sciences Center and University of Toronto, Toronto, Canada.
authors.forename: Scott
authors.initials: S
authors.lastname: Walsh
authors.affiliation: Division of Dermatology, Department of Medicine, Sunnybrook Health Sciences Center and University of Toronto, Toronto, Canada.
authors.forename: Neil
authors.initials: N
authors.lastname: Shear
keywords: erosions; lichen planus; mucous membranes; oral cavity