title: Pancreatic solitary fibrous tumor in a toddler managed by pancreaticoduodenectomy: a case report and review of the literature.
abstract: Solitary fibrous tumor (SFT) of the pancreas is rare, with 15 adult cases reported in the English literature. We described a 14-month-old boy who presented with obstructive jaundice. Dominantly elevated serum CA19-9 was detected. Imaging studies revealed a well-circumscribed, solid mass in the pancreatic head. A pancreaticoduodenectomy (child procedure) was performed using Shen's anastomosis technique. After resection of the tumor, liver function and serum tumor markers normalized and clinical signs receded. The boy was disease free after a follow-up of 12 months. Histological examination showed the tumor consisted of "patternless pattern" arranged spindle tumor cells and keloid-like hyalinized collagen. Immunohistochemical staining was positive for CD34 and vimentin. Mutation analysis ofCTNNB1was negative. To the best of our knowledge, our patient was the first case of pancreatic SFT in a pediatric population. SFT should be considered in differential diagnosis when confronted with a pancreatic tumor in children. Complete resection should be meticulously pursued.
authors.affiliation: Department of General Surgery, Shanghai Children's Hospital.
authors.forename: Qingfeng
authors.initials: Q
authors.lastname: Sheng
authors.affiliation: Department of General Surgery, Shanghai Children's Hospital.
authors.forename: Weijue
authors.initials: W
authors.lastname: Xu
authors.affiliation: Department of General Surgery, Shanghai Children's Hospital.
authors.forename: Jiangbin
authors.initials: J
authors.lastname: Liu
authors.affiliation: Department of General Surgery, Rui Jin Hospital.
authors.forename: Baiyong
authors.initials: B
authors.lastname: Shen
authors.affiliation: Department of General Surgery, Rui Jin Hospital.
authors.forename: Xiaxing
authors.initials: X
authors.lastname: Deng
authors.affiliation: Department of General Surgery, Shanghai Children's Hospital.
authors.forename: Yibo
authors.initials: Y
authors.lastname: Wu
authors.affiliation: Department of General Surgery, Shanghai Children's Hospital.
authors.forename: Wei
authors.initials: W
authors.lastname: Wu
authors.affiliation: Department of General Surgery, Shanghai Children's Hospital.
authors.forename: Shenghua
authors.initials: S
authors.lastname: Yu
authors.affiliation: Department of Pathology, Shanghai Children's Hospital, Shanghai Jiao Tong University, Shanghai, People's Republic of China.
authors.forename: Xueli
authors.initials: X
authors.lastname: Wang
authors.affiliation: Department of General Surgery, Shanghai Children's Hospital.
authors.forename: Zhibao
authors.initials: Z
authors.lastname: Lv
keywords: children; pancreas; rare pediatric tumors; rare tumors