title: Successful Management of Zoon's Balanitis with Topical Mupirocin Ointment: A Case Report and Literature Review of Mupirocin-Responsive Balanitis Circumscripta Plasmacelluaris.
abstract: BACKGROUND
  Zoon's balanitis, also referred to as balanitis circumscripta plasmacellularis (BCP), is an idiopathic, benign inflammatory condition of the glans penis and foreskin most often seen in elderly uncircumcised men. A patient with a biopsy-confirmed diagnosis of BCP who was successfully treated with topical mupirocin ointment is described.
  
  
  METHODS
  The PubMed database was searched with the key words: bactroban, balanitis, cell, circumscripta, mupirocin, plasma, plasmacellularis, tacrolimus, Zoon. The papers generated by the search and their references were reviewed.
  
  
  RESULTS
  Treatments for BCP have previously included circumcision and topical calcineurin inhibitors. Our patient with BCP rapidly resolved after initiating treatment with mupirocin 2% ointment.
  
  
  CONCLUSIONS
  BCP is a benign dermatosis affecting the glans penis and foreskin. We confirm an earlier observation demonstrating successful management of this condition with topical mupirocin 2% ointment. Previously reported therapies include circumcision, topical calcineurin inhibitors, phototherapy, and laser therapy. However, based on our observations, topical mupirocin 2% ointment therapy may be considered for the initial management of patients with suspected BCP. Prompt response to mupirocin 2% ointment is highly suggestive of the diagnosis of BCP since morphologically similar skin conditions do not respond to this treatment.
authors.affiliation: School of Medicine, University of California San Diego, La Jolla, CA, USA. obari@ucsd.edu.
authors.forename: Omar
authors.initials: O
authors.lastname: Bari
authors.affiliation: Department of Dermatology, University of California San Diego, La Jolla, CA, USA. mitehead@gmail.com.
authors.forename: Philip R
authors.initials: PR
authors.lastname: Cohen
keywords: Bactroban; Balanitis; Cell; Circumscripta; Mupirocin; Plasma; Plasmacellularis; Tacrolimus; Zoon