title: Long-term follow-up of patients with CLL treated with the selective Bruton's tyrosine kinase inhibitor ONO/GS-4059.
authors.affiliation: Ernest and Helen Scott Haematological Research Institute, University of Leicester, Leicester, United Kingdom.
authors.forename: Harriet S
authors.identifier: 0000-0003-2618-711X
authors.initials: HS
authors.lastname: Walter
authors.affiliation: Ernest and Helen Scott Haematological Research Institute, University of Leicester, Leicester, United Kingdom.
authors.forename: Sandrine
authors.identifier: 0000-0003-1870-9782
authors.initials: S
authors.lastname: Jayne
authors.affiliation: Department of Clinical Haematology, Plymouth University Peninsula Schools of Medicine and Dentistry, Plymouth, United Kingdom.
authors.forename: Simon A
authors.identifier: 0000-0001-8937-6351
authors.initials: SA
authors.lastname: Rule
authors.affiliation: Department of Clinical Hematology and Unité Mixte de Recherche-Centre National de la Recherche Scientifique 5235, Centre Hospitalier Régional Universitaire, Montpellier, France.
authors.forename: Guillaume
authors.initials: G
authors.lastname: Cartron
authors.affiliation: EA 7365 Groupe de Recherche sur les Formes Injectables et les Technologies Associées, University of Lille, Lille, France.|Department of Hematology, Centre Hospitalier Régional Universitaire, Lille, France.
authors.forename: Franck
authors.identifier: 0000-0002-3714-9824
authors.initials: F
authors.lastname: Morschhauser
authors.affiliation: Ernest and Helen Scott Haematological Research Institute, University of Leicester, Leicester, United Kingdom.
authors.forename: Salvador
authors.identifier: 0000-0003-1963-8840
authors.initials: S
authors.lastname: Macip
authors.affiliation: Hospices Civils de Lyon, Centre Hospitalier Lyon Sud, Service d'Hématologie, Pierre-Bénite, Université Claude Bernard Lyon 1, Lyon, France.
authors.forename: Lionel
authors.initials: L
authors.lastname: Karlin
authors.affiliation: Cardiff Chronic Lymphocytic Leukemia Research Group, School of Medicine, Cardiff University, Cardiff, United Kingdom; and.
authors.forename: Ceri
authors.initials: C
authors.lastname: Jones
authors.affiliation: EA 7365 Groupe de Recherche sur les Formes Injectables et les Technologies Associées, University of Lille, Lille, France.|Department of Hematology, Centre Hospitalier Régional Universitaire, Lille, France.
authors.forename: Charles
authors.initials: C
authors.lastname: Herbaux
authors.affiliation: Department of Clinical Hematology and Unité Mixte de Recherche-Centre National de la Recherche Scientifique 5235, Centre Hospitalier Régional Universitaire, Montpellier, France.
authors.forename: Philippe
authors.initials: P
authors.lastname: Quittet
authors.affiliation: Department of Clinical Haematology, Plymouth University Peninsula Schools of Medicine and Dentistry, Plymouth, United Kingdom.
authors.forename: Nimish
authors.initials: N
authors.lastname: Shah
authors.affiliation: Ernest and Helen Scott Haematological Research Institute, University of Leicester, Leicester, United Kingdom.|Department of Clinical Haematology, Plymouth University Peninsula Schools of Medicine and Dentistry, Plymouth, United Kingdom.
authors.forename: Claire V
authors.initials: CV
authors.lastname: Hutchinson
authors.affiliation: Cardiff Chronic Lymphocytic Leukemia Research Group, School of Medicine, Cardiff University, Cardiff, United Kingdom; and.
authors.forename: Christopher
authors.identifier: 0000-0001-9685-0621
authors.initials: C
authors.lastname: Fegan
authors.affiliation: Gilead Sciences, Inc, Foster City, CA.
authors.forename: Yingsi
authors.initials: Y
authors.lastname: Yang
authors.affiliation: Gilead Sciences, Inc, Foster City, CA.
authors.forename: Siddhartha
authors.initials: S
authors.lastname: Mitra
authors.affiliation: Hospices Civils de Lyon, Centre Hospitalier Lyon Sud, Service d'Hématologie, Pierre-Bénite, Université Claude Bernard Lyon 1, Lyon, France.
authors.forename: Gilles
authors.identifier: 0000-0002-9541-8666
authors.initials: G
authors.lastname: Salles
authors.affiliation: Ernest and Helen Scott Haematological Research Institute, University of Leicester, Leicester, United Kingdom.
authors.forename: Martin J S
authors.identifier: 0000-0002-5033-2236
authors.initials: MJS
authors.lastname: Dyer
mesh_terms: D000077329:Agammaglobulinaemia Tyrosine Kinase; D018572:Disease-Free Survival; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007093:Imidazoles / Q000008:administration & dosage* / Q000009:adverse effects; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000188:drug therapy* / Q000453:epidemiology / Q000401:mortality*; D008297:Male; D011505:Protein-Tyrosine Kinases / Q000037:antagonists & inhibitors*; D011743:Pyrimidines / Q000008:administration & dosage* / Q000009:adverse effects; D015996:Survival Rate
chemical_list: D007093:Imidazoles; D011743:Pyrimidines; D011505:Protein-Tyrosine Kinases; D000077329:Agammaglobulinaemia Tyrosine Kinase; C000608238:tirabrutinib