title: Additional values of high-resolution gadoxetic acid-enhanced MR cholangiography for evaluating the biliary anatomy of living liver donors: Comparison with T2-weighted MR cholangiography and conventional gadoxetic acid-enhanced MR cholangiography.
abstract: To determine the incremental value of small field of view (sFOV) high-resolution (HR) gadoxetic acid-enhanced 3D T1-weighted (W) magnetic resonance cholangiography (MRC) for evaluating the biliary anatomy of potential living donors by comparing it to T2W-MRC.
  
  
  
  In all, 73 living donor candidates underwent gadoxetic acid-enhanced MRI (3.0T) including three kinds of MRCs: 3D multislice T2W-MRC, regular FOV (rFOV) (380 × 380mm, resolution 1.0 × 1.2 × 3.0 mm) 3D T1W-MRC, and sFOV (256 × 208 mm, resolution 1.0 × 1.0 × 1.0 mm) HR-T1W-MRC. Three radiologists reviewed the image sets for the visibility of segmental intrahepatic bile ducts (BDs), biliary anatomy with its confidence level, and expected number of BD openings at right hemihepatectomy.
  
  
  
  Compared to T2W-MRC alone, the combination of sFOV HR-T1W-MRC and T2W-MRC (sT1W-HR set) yielded significantly improved BD visibility scores (P < 0.01) and confidence levels for biliary anatomy (P < 0.01). Compared to the rT1W set (rFOV T1W-MRC with T2W MRC), the sFOV HR set showed significantly increased caudate duct visibility (P < 0.001). In the case of T2W-MRC presenting subdiagnostic image quality, the addition of sFOV HRT1W-MRC provided diagnostically acceptable image visibility (53.8∼90%) to all reviewers. The addition of sFOV HR-T1W-MRC resulted in a significantly higher consistency with the operative record and expected number of BD openings than did T2W-MRC alone (P < 0.05 in all reviewers) or rFOV set (P < 0.05 in one reviewer) with excellent interobserver agreement of both T1W-MRC sets.
  
  
  
  The combination of sFOV HR-T1W-MRC and T2W-MRC significantly improved BD visibility and confidence levels for biliary anatomy compared to T2W-MRC alone, thereby allowing accurate biliary anatomy assessment in most patients with subdiagnostic T2W-MRC images.
  
  
  
  3 Technical Efficacy: Stage 2 J. Magn. Reson. Imaging 2018;47:152-159.
authors.affiliation: Department of Radiology, Seoul National University Hospital, Seoul, Korea.
authors.forename: Hyo-Jin
authors.initials: HJ
authors.lastname: Kang
authors.affiliation: Department of Radiology, Seoul National University Hospital, Seoul, Korea.|Institute of Radiation Medicine, Seoul National University College Medical Research Center, Seoul, Korea.
authors.forename: Jeong Min
authors.initials: JM
authors.lastname: Lee
authors.affiliation: Department of Radiology, Seoul National University Hospital, Seoul, Korea.
authors.forename: Jeong Hee
authors.initials: JH
authors.lastname: Yoon
authors.affiliation: Department of Radiology, Seoul National University Hospital, Seoul, Korea.
authors.forename: Ijin
authors.initials: I
authors.lastname: Joo
authors.affiliation: Department of Radiology, Seoul National University Bundang Hospital, Seongnam-si, Korea.
authors.forename: Won
authors.initials: W
authors.lastname: Chang
authors.affiliation: Department of General Surgery, Seoul National University Hospital, Seoul, Korea.
authors.forename: Kyung-Suk
authors.initials: KS
authors.lastname: Suh
authors.affiliation: Department of General Surgery, Seoul National University Hospital, Seoul, Korea.
authors.forename: Kwang-Woong
authors.initials: KW
authors.lastname: Lee
authors.affiliation: Department of General Surgery, Seoul National University Hospital, Seoul, Korea.
authors.forename: Nam-Joon
authors.initials: NJ
authors.lastname: Yi
authors.affiliation: Department of Radiology, Seoul National University Hospital, Seoul, Korea.|Institute of Radiation Medicine, Seoul National University College Medical Research Center, Seoul, Korea.
authors.forename: Joon Koo
authors.initials: JK
authors.lastname: Han
mesh_terms: D000293:Adolescent; D000328:Adult; D001652:Bile Ducts / Q000000981:diagnostic imaging; D001659:Biliary Tract / Q000000981:diagnostic imaging*; D049448:Cholangiopancreatography, Magnetic Resonance; D003287:Contrast Media / Q000737:chemistry; D005260:Female; D019786:Gadolinium DTPA / Q000737:chemistry*; D006498:Hepatectomy; D006801:Humans; D007091:Image Processing, Computer-Assisted; D021621:Imaging, Three-Dimensional; D008099:Liver / Q000000981:diagnostic imaging; D016031:Liver Transplantation; D019520:Living Donors; D008297:Male; D008875:Middle Aged; D015588:Observer Variation; D011871:Radiology; D012189:Retrospective Studies; D055815:Young Adult
chemical_list: D003287:Contrast Media; C073590:gadolinium ethoxybenzyl DTPA; D019786:Gadolinium DTPA
keywords: bile duct anatomy; high resolution T1W-MRC; liver transplantation; living liver donor; magnetic resonance cholangiography; small FOV