title: Degos-Like Lesions Associated with Systemic Lupus Erythematosus.
abstract: Degos disease, also referred to as malignant atrophic papulosis, was first described in 1941 by Köhlmeier and was independently described by Degos in 1942. Degos disease is characterized by diffuse, papular skin eruptions with porcelain-white centers and slightly raised erythematous telangiectatic rims associated with bowel infarction. Although the etiology of Degos disease is unknown, autoimmune diseases, coagulation disorders, and vasculitis have all been considered as underlying pathogenic mechanisms. Approximately 15% of Degos disease have a benign course limited to the skin and no history of gastrointestinal or central nervous system (CNS) involvement. A 29-year-old female with history of systemic lupus erythematosus (SLE) presented with a 2-year history of asymptomatic lesions on the dorsum of all fingers and both knees. The patient had only skin lesions and no gastrointestinal or CNS vasculitis symptoms. Her skin lesions were umbilicated, atrophic porcelain-white lesions with a rim of erythema. On the basis of clinical, histologic, and laboratory findings, a diagnosis of Degos-like lesions associated with SLE was made. The patient had been treated for SLE for 7 years. Her treatment regimen was maintained over a 2 month follow-up period, and the skin lesions improved slightly with no development of new lesions.
authors.affiliation: Department of Dermatology, Kosin University College of Medicine, Busan, Korea.
authors.forename: Min Soo
authors.initials: MS
authors.lastname: Jang
authors.affiliation: Department of Dermatology, Kosin University College of Medicine, Busan, Korea.
authors.forename: Jong Bin
authors.initials: JB
authors.lastname: Park
authors.affiliation: Department of Dermatology, Kosin University College of Medicine, Busan, Korea.
authors.forename: Myeong Hyeon
authors.initials: MH
authors.lastname: Yang
authors.affiliation: Department of Dermatology, Kosin University College of Medicine, Busan, Korea.
authors.forename: Ji Yun
authors.initials: JY
authors.lastname: Jang
authors.affiliation: Department of Dermatology, Kosin University College of Medicine, Busan, Korea.
authors.forename: Joon Hee
authors.initials: JH
authors.lastname: Kim
authors.affiliation: Department of Dermatology, Kosin University College of Medicine, Busan, Korea.
authors.forename: Kang Hoon
authors.initials: KH
authors.lastname: Lee
authors.affiliation: Department of Internal Medicine, Kosin University College of Medicine, Busan, Korea.
authors.forename: Geun Tae
authors.initials: GT
authors.lastname: Kim
authors.affiliation: Department of Dermatology, Kosin University College of Medicine, Busan, Korea.
authors.forename: Hyun
authors.initials: H
authors.lastname: Hwangbo
authors.affiliation: Department of Dermatology, Kosin University College of Medicine, Busan, Korea.
authors.forename: Kee Suck
authors.initials: KS
authors.lastname: Suh
keywords: Degos disease; Degos-like lesions; Systemic lupus erythematosus