title: Evaluation of Choroidal and Retinal Thickness Changes in Parkinson's Disease Using Spectral Domain Optical Coherence Tomography.
abstract: OBJECTIVE
  The purpose of this study was to evaluate retinal and choroidal thickness in patients with Parkinson's disease (PD) using spectral domain-optical coherence tomography (SD-OCT).
  
  
  METHODS
  Participants in our study were 31 PD patients and 25 age-matched healthy controls. All participants underwent best-corrected visual acuity (BCVA) measurement, slit-lamp biomicroscopy, dilated fundoscopy, and SD-OCT. Macular and retinal nerve fiber layer (RNFL) thickness and choroidal thickness in all quadrants were recorded.
  
  
  RESULTS
  There was a statistically significant reduction in average, superior, and temporal RNFL thickness, average ganglion cell complex, and choroidal thickness in the subfoveal area and in all quadrants between patients with PD and controls.
  
  
  CONCLUSIONS
  The role of the choroidal vasculature in the pathophysiology of PD should be further scrutinized.
authors.affiliation: a Electrophysiology Laboratory, 1st Department of Ophthalmology , University of Athens , Athens , Greece.
authors.forename: Marilita M
authors.initials: MM
authors.lastname: Moschos
authors.affiliation: a Electrophysiology Laboratory, 1st Department of Ophthalmology , University of Athens , Athens , Greece.
authors.forename: Irini P
authors.initials: IP
authors.lastname: Chatziralli
mesh_terms: D000368:Aged; D002829:Choroid / Q000473:pathology*; D015862:Choroid Diseases / Q000175:diagnosis* / Q000209:etiology / Q000503:physiopathology; D003430:Cross-Sectional Studies; D018450:Disease Progression; D005260:Female; D006801:Humans; D008297:Male; D009412:Nerve Fibers / Q000473:pathology; D010300:Parkinson Disease / Q000150:complications / Q000175:diagnosis*; D012164:Retinal Diseases / Q000175:diagnosis* / Q000209:etiology / Q000503:physiopathology; D012165:Retinal Ganglion Cells / Q000473:pathology*; D041623:Tomography, Optical Coherence / Q000379:methods*; D014792:Visual Acuity
keywords: Choroid; OCT; Parkinson’s Disease; retinal thickness