title: Descemet membrane endothelial keratoplasty (DMEK) early stage graft failure in eyes with preexisting glaucoma.
abstract: OBJECTIVE
  To evaluate the effect of a preexisting glaucoma on the early postoperative outcome of a descemet membrane endothelial keratoplasty (DMEK).
  
  
  METHODS
  All patients who underwent DMEK surgery at the Department of Ophthalmology of the University of Muenster with a follow-up of at least 3 months (90d) were included in this study. The best corrected distance visual acuity (BCDVA), the intraocular pressure (IOD), the rate of re-keratoplasty and the rebubbling rate were inter alia recorded. The results of patients with (group 1) and without a preexisting glaucoma (group 2) were compared.
  
  
  RESULTS
  74 eyes of 59 patients with a mean follow-up of 152 ± 70 days were included. 65 eyes were in group 1 and 9 eyes in group 2. The BCDVA significantly improved in both groups after surgery (p < 0.03). The Re-keratoplasty rate (p = 0.172), the number of rebubblings per patient (p = 0.571) and the rebubbling rate (p = 0.939) were not significantly different in patients without glaucoma compared to patients with a preexisting glaucoma.
  
  
  CONCLUSIONS
  In the early stage outcome of DMEK no significant impact of a preexisting glaucoma was found.
authors.affiliation: Department of Ophthalmology, University of Muenster Medical Center, Domagkstraße 15, 48149, Muenster, Germany. maximilian.treder@ukmuenster.de.
authors.forename: Maximilian
authors.identifier: http://orcid.org/0000-0002-8533-6026
authors.initials: M
authors.lastname: Treder
authors.affiliation: Department of Ophthalmology, University of Muenster Medical Center, Domagkstraße 15, 48149, Muenster, Germany.
authors.forename: Maged
authors.initials: M
authors.lastname: Alnawaiseh
authors.affiliation: Department of Ophthalmology, University of Muenster Medical Center, Domagkstraße 15, 48149, Muenster, Germany.
authors.forename: Nicole
authors.initials: N
authors.lastname: Eter
mesh_terms: D000368:Aged; D003316:Corneal Diseases / Q000150:complications / Q000175:diagnosis / Q000601:surgery*; D057111:Descemet Stripping Endothelial Keratoplasty / Q000009:adverse effects*; D005260:Female; D005500:Follow-Up Studies; D005901:Glaucoma / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology; D006084:Graft Rejection / Q000175:diagnosis*; D006801:Humans; D007429:Intraocular Pressure; D008297:Male; D011183:Postoperative Complications; D012189:Retrospective Studies; D013997:Time Factors; D014792:Visual Acuity
keywords: Descemet membrane endothelial keratoplasty; Glaucoma; Graft failure; Lamellar keratoplasty; Re-keratoplasty