title: Catalytic Asymmetric Electrochemical Oxidative Coupling of Tertiary Amines with Simple Ketones.
abstract: Catalytic asymmetric electrochemical C-H functionalization of simple ketones has been developed. The transformation is realized by the combination of electrochemical oxidation and chiral primary amine catalysis. This metal- and oxidant-free method furnishes diverse C1-alkylated tetrahydroisoquinolines in high yields and with excellent enantioselectivities under very mild conditions.
authors.affiliation: Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences , Beijing 100190, China.|Department of Chemistry, University of Chinese Academy of Sciences , 10049 Beijing, China.|Collaborative Innovation Center of Chemical Science and Engineering (Tianjin) , Tianjin 300071, China.
authors.forename: Niankai
authors.initials: N
authors.lastname: Fu
authors.affiliation: Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences , Beijing 100190, China.|Department of Chemistry, University of Chinese Academy of Sciences , 10049 Beijing, China.
authors.forename: Longji
authors.initials: L
authors.lastname: Li
authors.affiliation: Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences , Beijing 100190, China.|Department of Chemistry, University of Chinese Academy of Sciences , 10049 Beijing, China.
authors.forename: Qi
authors.initials: Q
authors.lastname: Yang
authors.affiliation: Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences , Beijing 100190, China.|Department of Chemistry, University of Chinese Academy of Sciences , 10049 Beijing, China.|Collaborative Innovation Center of Chemical Science and Engineering (Tianjin) , Tianjin 300071, China.
authors.forename: Sanzhong
authors.identifier: 0000-0001-8714-4047
authors.initials: S
authors.lastname: Luo