title: Database selection in systematic reviews: an insight through clinical neurology.
abstract: BACKGROUND
  Failure to perform a comprehensive search when designing a systematic review (SR) can lead to bias, reducing the validity of review's conclusions.
  
  
  OBJECTIVE
  We examined the frequency and choice of databases used by reviewers in clinical neurology.
  
  
  METHODS
  Ninety-five SRs and/or meta-analyses were located across five prominent neurology journals between 2008 and 2014. Methods sections were reviewed, and all bibliographic databases were coded.
  
  
  RESULTS
  On average, 2.59 databases were used in SR searches. Seven reviews included an information specialist, and these reviews reported a greater number of information sources used during the search process. Thirty-nine databases were reported across studies. PubMed/MEDLINE®and EMBASE were cited most frequently.
  
  
  CONCLUSIONS
  Searching too few databases may reduce the validity and generalisability of SR results. We found that the majority of systematic reviewers in clinical neurology do not search an adequate number of databases, which may yield a biased sample of primary studies and, thus, may influence the accuracy of summary effects.
  
  
  CONCLUSIONS
  Systematic reviewers should aim to search a sufficient number of databases to minimise selection bias. Additionally, systematic reviewers should include information specialists in designing SR methodology, as this may improve systematic review quality.
authors.affiliation: Oklahoma State University Center for Health Sciences, Tulsa, OK, USA.
authors.forename: Matt
authors.initials: M
authors.lastname: Vassar
authors.affiliation: Oklahoma State University Center for Health Sciences, Tulsa, OK, USA.
authors.forename: Vadim
authors.initials: V
authors.lastname: Yerokhin
authors.affiliation: Oklahoma State University Center for Health Sciences, Tulsa, OK, USA.
authors.forename: Philip Marcus
authors.initials: PM
authors.lastname: Sinnett
authors.affiliation: Oklahoma State University Center for Health Sciences, Tulsa, OK, USA.
authors.forename: Matthew
authors.initials: M
authors.lastname: Weiher
authors.affiliation: Oklahoma State University Center for Health Sciences, Tulsa, OK, USA.
authors.forename: Halie
authors.initials: H
authors.lastname: Muckelrath
authors.affiliation: Oklahoma State University Center for Health Sciences, Tulsa, OK, USA.
authors.forename: Branden
authors.initials: B
authors.lastname: Carr
authors.affiliation: Oklahoma State University Center for Health Sciences, Tulsa, OK, USA.
authors.forename: Laura
authors.initials: L
authors.lastname: Varney
authors.affiliation: Oklahoma State University Center for Health Sciences, Tulsa, OK, USA.
authors.forename: Gregory
authors.initials: G
authors.lastname: Cook
mesh_terms: D016206:Databases, Bibliographic; D016208:Databases, Factual; D006801:Humans; D016239:MEDLINE; D009462:Neurology; D039781:PubMed; D012196:Review Literature as Topic
keywords: bibliometrics; database searching; evidence-based medicine; health care; libraries; review and systematic search