title: Whole-Genome Comparative Analysis of Salmonella enterica Serovar Newport Strains Reveals Lineage-Specific Divergence.
abstract: Salmonella enterica subsp. enterica serovar Newport has been associated with various foodborne outbreaks in humans and animals. Phylogenetically, serovar Newport is one of several Salmonella serovars that are polyphyletic. To understand more about the polyphyletic nature of this serovar, six food, environment, and human isolates from different Newport lineages were selected for genome comparison analyses. Whole genome comparisons demonstrated that heterogeneity mostly occurred in the prophage regions. Lineage-specific characteristics were also present in the Salmonella pathogenicity islands and fimbrial operons.
authors.affiliation: Center for Food Safety and Nutrition, U.S. Food and Drug Administration, College Park, Maryland.
authors.forename: Jie
authors.initials: J
authors.lastname: Zheng
authors.affiliation: Center for Food Safety and Nutrition, U.S. Food and Drug Administration, College Park, Maryland.
authors.forename: Yan
authors.initials: Y
authors.lastname: Luo
authors.affiliation: Center for Food Safety and Nutrition, U.S. Food and Drug Administration, College Park, Maryland.
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Reed
authors.affiliation: Center for Food Safety and Nutrition, U.S. Food and Drug Administration, College Park, Maryland.
authors.forename: Rebecca
authors.initials: R
authors.lastname: Bell
authors.affiliation: Center for Food Safety and Nutrition, U.S. Food and Drug Administration, College Park, Maryland.
authors.forename: Eric W
authors.initials: EW
authors.lastname: Brown
authors.affiliation: Center for Food Safety and Nutrition, U.S. Food and Drug Administration, College Park, Maryland.
authors.forename: Maria
authors.initials: M
authors.lastname: Hoffmann
keywords: Salmonella Newport; complete genome; lineage divergence