title: Follicular lymphoma: State-of-the-art ICML workshop in Lugano 2015.
abstract: The 13th International Conference on Malignant Lymphoma held in Lugano in June 2015 was preceded by a closed workshop (organized in collaboration with the American Association for Cancer Research and the European School of Oncology) with the aim of developing an up-to-date understanding of the biology of follicular lymphoma and the clinical implications of new findings in the field. Discussed topics included the mutational spectrum at diagnosis, the clinical correlates of genetic and epigenetic alterations, the mechanisms of clonal evolution and histological transformation, the cross talk between tumor cells and microenvironment, and the development of novel treatments. This report represents a summary of the workshop.
authors.affiliation: Department of Pathology and the Centre for Lymphoid Cancer, British Columbia Cancer Agency and University of BC, Vancouver, BC, Canada.
authors.forename: Randy D
authors.initials: RD
authors.lastname: Gascoyne
authors.affiliation: Centre d'Immunologie de Marseille-Luminy, Aix Marseille Université UM2, Marseille, France.
authors.forename: Bertrand
authors.initials: B
authors.lastname: Nadel
authors.affiliation: Institute of Cancer Genetics, Department of Pathology and Cell Biology, Herbert Irving Comprehensive Cancer Center, Columbia University, New York, New York, USA.
authors.forename: Laura
authors.initials: L
authors.lastname: Pasqualucci
authors.affiliation: Centre for Haemato-Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK.
authors.forename: Jude
authors.initials: J
authors.lastname: Fitzgibbon
authors.affiliation: Department of Pathology and Immunology and Siteman Cancer Center, Washington University School of Medicine, Saint Louis, Missouri, USA.
authors.forename: Jacqueline E
authors.initials: JE
authors.lastname: Payton
authors.affiliation: Weill Cornell Cancer Center and Department of Medicine, Weill Cornell Medicine, New York, New York, USA.
authors.forename: Ari
authors.initials: A
authors.lastname: Melnick
authors.affiliation: Department of Medicine III, Laboratory for Experimental Leukemia and Lymphoma Research (ELLF), Ludwig-Maximilians-University, Munich, Germany.
authors.forename: Oliver
authors.initials: O
authors.lastname: Weigert
authors.affiliation: UMR INSERM U917, Equipe Labellisée Ligue Contre le Cancer, Université Rennes 1, Rennes, France.
authors.forename: Karin
authors.initials: K
authors.lastname: Tarte
authors.affiliation: Centre for Haemato-Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK.
authors.forename: John G
authors.initials: JG
authors.lastname: Gribben
authors.affiliation: Wilmot Cancer Institute, University of Rochester, Rochester, New York, USA.
authors.forename: Jonathan W
authors.initials: JW
authors.lastname: Friedberg
authors.affiliation: Department of Haematology, Peter MacCallum Cancer Centre, and University of Melbourne, Parkville, Victoria, Australia.
authors.forename: John F
authors.initials: JF
authors.lastname: Seymour
authors.affiliation: Oncology Institute of Southern Switzerland, Ospedale San Giovanni, Bellinzona, Switzerland.
authors.forename: Franco
authors.initials: F
authors.lastname: Cavalli
authors.affiliation: Oncology Institute of Southern Switzerland, Ospedale San Giovanni, Bellinzona, Switzerland.
authors.forename: Emanuele
authors.identifier: http://orcid.org/0000-0002-5522-6109
authors.initials: E
authors.lastname: Zucca
mesh_terms: D005260:Female; D049674:History, 21st Century; D006801:Humans; D008224:Lymphoma, Follicular; D008297:Male; D013557:Switzerland
keywords: cancer epigenetics; cancer genetics; follicular lymphoma; histological transformation; lymphoma microenvironment treatment