title: Physiotherapy and Speech and Language therapy intervention for chronic cough.
abstract: There are few effective pharmacological therapies available to treat refractory chronic cough. Functional MRI studies of the brain have recently shown that patients with chronic cough have dysfunctional inhibitory control of cough. Self-management therapies delivered by physiotherapists or speech therapists are effective at suppressing cough. They enable patients to consciously suppress the urge to cough. The intervention consists of education, laryngeal hygiene, cough suppression and distraction measures and behaviour modification. The efficacy of Physiotherapy and Speech And Language Intervention (PSALTI) has been confirmed in two randomised control trials. In one trial, there was a 41% reduction in cough frequency with PSALTI, assessed objectively with the Leicester Cough Monitor, and a clinically significant improvement in quality of life. Importantly, the improvement in cough was sustained when therapy was discontinued. The addition of the Speech Pathology Treatment to neuromodulator drug therapy, Pregabalin has also been evaluated in a clinical trial. There was a clinically significant improvement in quality of life, and this was sustained when therapy was discontinued. The mechanism of action of PSALTI is not known and this should be investigated in future. Further studies are needed to identify the components of PSALTI that deliver the most benefit, and determine whether PSALTI is effective in cough associated with other chronic lung disorders.
authors.affiliation: King's College London, Division of Asthma, Allergy and Lung Biology, London, UK. Electronic address: surinder.birring@nhs.net.
authors.forename: Surinder S
authors.initials: SS
authors.lastname: Birring
authors.affiliation: Department of Physiotherapy, King's College Hospital, London, UK.
authors.forename: Sarah
authors.initials: S
authors.lastname: Floyd
authors.affiliation: Department of Physiotherapy, King's College Hospital, London, UK.
authors.forename: Charles C
authors.initials: CC
authors.lastname: Reilly
authors.affiliation: King's College London, Division of Asthma, Allergy and Lung Biology, London, UK.
authors.forename: Peter Siu Pan
authors.initials: PSP
authors.lastname: Cho
mesh_terms: D001921:Brain / Q000000981:diagnostic imaging; D002908:Chronic Disease; D003131:Combined Modality Therapy; D003371:Cough / Q000503:physiopathology / Q000628:therapy*; D006801:Humans; D007808:Language Therapy / Q000379:methods; D008279:Magnetic Resonance Imaging; D026741:Physical Therapy Modalities; D000069583:Pregabalin / Q000627:therapeutic use; D011788:Quality of Life; D016032:Randomized Controlled Trials as Topic; D013070:Speech Therapy / Q000379:methods*
chemical_list: D000069583:Pregabalin
keywords: Chronic cough; Cough hypersensitivity syndrome; PSALTI; Physiotherapy; Speech and Language therapy