title: MR-guided radiation therapy: transformative technology and its role in the central nervous system.
abstract: This review article describes advancement of magnetic resonance imaging technologies in radiation therapy planning, guidance, and adaptation of brain tumors. The potential for MR-guided radiation therapy to improve outcomes and the challenges in its adoption are discussed.
authors.affiliation: Departments of Radiation Oncology, University of Michigan, Ann Arbor, Michigan, USA.|Radiology, University of Michigan, Ann Arbor, Michigan, USA.|Biomedical Engineering, University of Michigan, Ann Arbor, Michigan, USA.
authors.forename: Yue
authors.initials: Y
authors.lastname: Cao
authors.affiliation: Department of Radiation Oncology, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada.
authors.forename: Chia-Lin
authors.initials: CL
authors.lastname: Tseng
authors.affiliation: Departments of Radiation Oncology, University of Michigan, Ann Arbor, Michigan, USA.
authors.forename: James M
authors.initials: JM
authors.lastname: Balter
authors.affiliation: Departments of Radiation Oncology, University of Michigan, Ann Arbor, Michigan, USA.|Department of Radiation Oncology, Shandong Cancer Hospital, Shandong University, Jinan, China.
authors.forename: Feifei
authors.initials: F
authors.lastname: Teng
authors.affiliation: Radiology, University of Michigan, Ann Arbor, Michigan, USA.
authors.forename: Hemant A
authors.initials: HA
authors.lastname: Parmar
authors.affiliation: Department of Radiation Oncology, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada.
authors.forename: Arjun
authors.initials: A
authors.lastname: Sahgal
mesh_terms: D001932:Brain Neoplasms / Q000532:radiotherapy* / Q000556:secondary; D003072:Cognition Disorders / Q000209:etiology; D005909:Glioblastoma / Q000532:radiotherapy*; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D011880:Radiotherapy Planning, Computer-Assisted / Q000379:methods*; D061089:Radiotherapy, Image-Guided / Q000009:adverse effects / Q000379:methods*; D016896:Treatment Outcome
keywords: MRI-linac systems; brain tumors; magnetic resonance imaging; metabolic and physiological imaging; radiation therapy