title: Correlation of ABO blood groups with spontaneous recanalization in acute myocardial infarction.
abstract: OBJECTIVE
  Although previous studies have demonstrated the relationship between ABO blood groups and cardiovascular disease, the association of ABO blood type with spontaneous recanalization (SR) in patients with acute myocardial infarction (AMI) has not been previously investigated.
  
  
  METHODS
  We performed an initial exploratory study on the association of ABO blood groups with the presence of SR in 1209 patients with AMI. They were divided into two groups according to the thrombolysis in myocardial infarction (TIMI) grades: no-SR group (TIMI 0-1, n = 442) and SR group (TIMI 2-3, n = 767). To confirm our primary findings, data from a second AMI population (n = 200) was analyzed.
  
  
  RESULTS
  In the initial data, SR group had a significantly higher percentage of blood type O and a lower percentage of blood type A compared to the no-SR group. Multivariate logistic regression analysis showed that blood type O was positively associated with SR (odds ratio: 1.40, 95% confidence interval: 1.05-1.87, p = .02), and this finding was confirmed in our second population.
  
  
  CONCLUSIONS
  The present study demonstrates that blood type O was independently and positively associated with an open culprit artery in patients with AMI, suggesting that the ABO blood type is not only associated with the susceptibility to coronary artery disease but also to spontaneous reperfusion in AMI patients.
authors.affiliation: a Division of Dyslipidemia , State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College , Beijing , China.|b Department of Cardiology , FuzhouGeneral Hospital of Nanjing Command , Fuzhou , China.
authors.forename: Xian-Liang
authors.initials: XL
authors.lastname: Lin
authors.affiliation: a Division of Dyslipidemia , State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College , Beijing , China.
authors.forename: Bing-Yang
authors.initials: BY
authors.lastname: Zhou
authors.affiliation: a Division of Dyslipidemia , State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College , Beijing , China.
authors.forename: Sha
authors.initials: S
authors.lastname: Li
authors.affiliation: a Division of Dyslipidemia , State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College , Beijing , China.
authors.forename: Xiao-Lin
authors.initials: XL
authors.lastname: Li
authors.affiliation: b Department of Cardiology , FuzhouGeneral Hospital of Nanjing Command , Fuzhou , China.
authors.forename: Zhu-Rong
authors.initials: ZR
authors.lastname: Luo
authors.affiliation: a Division of Dyslipidemia , State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College , Beijing , China.
authors.forename: Jian-Jun
authors.initials: JJ
authors.lastname: Li
mesh_terms: D000017:ABO Blood-Group System; D000368:Aged; D002681:China; D017023:Coronary Angiography; D003324:Coronary Artery Disease / Q000097:blood* / Q000000981:diagnostic imaging / Q000503:physiopathology; D003326:Coronary Circulation; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D016017:Odds Ratio; D012075:Remission, Spontaneous; D000072657:ST Elevation Myocardial Infarction / Q000097:blood* / Q000000981:diagnostic imaging / Q000503:physiopathology
chemical_list: D000017:ABO Blood-Group System
keywords: ABO blood groups; acute myocardial infarction; blood type O; coronary artery disease; spontaneous recanalization