title: Rapid and automatic chemical identification of the medicinal flower buds of Lonicera plants by the benchtop and hand-held Fourier transform infrared spectroscopy.
abstract: With the utilization of the hand-held equipment, Fourier transform infrared (FT-IR) spectroscopy is a promising analytical technique to minimize the time cost for the chemical identification of herbal materials. This research examines the feasibility of the hand-held FT-IR spectrometer for the on-site testing of herbal materials, using Lonicerae Japonicae Flos (LJF) and Lonicerae Flos (LF) as examples. Correlation-based linear discriminant models for LJF and LF are established based on the benchtop and hand-held FT-IR instruments. The benchtop FT-IR models can exactly recognize all articles of LJF and LF. Although a few LF articles are misjudged at the sub-class level, the hand-held FT-IR models are able to exactly discriminate LJF and LF. As a direct and label-free analytical technique, FT-IR spectroscopy has great potential in the rapid and automatic chemical identification of herbal materials either in laboratories or in fields. This is helpful to prevent the spread and use of adulterated herbal materials in time.
authors.affiliation: School of Life Sciences, Beijing University of Chinese Medicine, Beijing 100029, China. Electronic address: chenjianbo@bucm.edu.cn.
authors.forename: Jianbo
authors.initials: J
authors.lastname: Chen
authors.affiliation: Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100193, China. Electronic address: guobaolin010@163.com.
authors.forename: Baolin
authors.initials: B
authors.lastname: Guo
authors.affiliation: Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100193, China.
authors.forename: Rui
authors.initials: R
authors.lastname: Yan
authors.affiliation: Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua University, Beijing 100084, China.
authors.forename: Suqin
authors.initials: S
authors.lastname: Sun
authors.affiliation: Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua University, Beijing 100084, China.
authors.forename: Qun
authors.initials: Q
authors.lastname: Zhou
mesh_terms: D016002:Discriminant Analysis; D035264:Flowers / Q000737:chemistry*; D031239:Lonicera / Q000737:chemistry*; D025341:Principal Component Analysis; D011786:Quality Control; D017550:Spectroscopy, Fourier Transform Infrared / Q000379:methods*; D013997:Time Factors
keywords: Chemical fingerprints; Lonicerae Flos; Lonicerae Japonicae Flos; Mid-infrared spectroscopy; Quality control