title: Body composition and frailty profiles in Brazilian older people: Frailty in Brazilian Older People Study-FIBRA-BR.
abstract: OBJECTIVE
  To determine the association between body composition and frailty in older Brazilian subjects.
  
  
  METHODS
  This is a Cross-sectional study called FIBRA-BR and developed in community Brazilian aged ≥65 (n=5638). Frailty was assessed according to Fried et al. definition and body composition was determined by BMI, waist circumference and waist-hip ratio.
  
  
  RESULTS
  The lowest prevalence of frailty was observed in subjects with BMI between 25.0 and 29.9kg/m2. Subjects with a BMI <18.5 and those with elevated WC presented a higher risk of frailty compared to eutrophic subjects (odds ratio (OR)=3.10; 95% CI: 2.06-4.67) and (OR=1.15; 95% CI: 1.03-1.27), respectively. Being overweight was protective for pre-frailty (OR=0.48; 95% CI: 0.4-0.58) and frailty (OR=0.77; 95% CI: 0.67-0.9). Obese older people presented a higher risk of pre-frailty only (OR=1.29; 95% CI: 1.09-1.51). Older people with high WC showed a greater proportion of frailty regardless of the BMI range.
  
  
  CONCLUSIONS
  Undernutrition is associated with pre-frailty and frailty in Brazilian elderly subjects, whereas obesity is associated only with pre-frailty. Overweight seems to have a protective effect against the syndrome. The excess of abdominal fat is associated with both profiles independent of the BMI.
authors.affiliation: Division of General Internal and Geriatric Medicine, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, SP, Brazil. Electronic address: eferriol@fmrp.usp.br.
authors.forename: Eduardo
authors.initials: E
authors.lastname: Ferriolli
authors.affiliation: Division of General Internal and Geriatric Medicine, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, SP, Brazil. Electronic address: fernandapessanha_fisio@hotmail.com.
authors.forename: Fernanda Pinheiro Amador Dos Santos
authors.initials: FPADS
authors.lastname: Pessanha
authors.affiliation: GeronLab, Internal Medicine Department, Health Science School, Rio de Janeiro State University, Rio de Janeiro, RJ, Brazil. Electronic address: virgilio.garcia.moreira@gmail.com.
authors.forename: Virgílio Garcia
authors.initials: VG
authors.lastname: Moreira
authors.affiliation: Division of Physiotherapy, School of Physiotherapy, Minas Gerais Federal University, Belo Horizonte, MG, Brazil. Electronic address: rcorreadias8@gmail.com.
authors.forename: Rosângela Corrêa
authors.initials: RC
authors.lastname: Dias
authors.affiliation: Department of Internal Medicine, Faculty of Medical Sciences, Campinas State University, Campinas, SP, Brazil. Electronic address: anitalbn@uol.com.br.
authors.forename: Anita Liberalesso
authors.initials: AL
authors.lastname: Neri
authors.affiliation: GeronLab, Internal Medicine Department, Health Science School, Rio de Janeiro State University, Rio de Janeiro, RJ, Brazil. Electronic address: roberto.lourenco@globo.com.
authors.forename: Roberto Alves
authors.initials: RA
authors.lastname: Lourenço
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001823:Body Composition; D015992:Body Mass Index; D001938:Brazil; D003430:Cross-Sectional Studies; D005260:Female; D000073496:Frailty; D006801:Humans; D008297:Male; D009765:Obesity / Q000378:metabolism; D050177:Overweight / Q000378:metabolism; D055105:Waist Circumference; D049629:Waist-Hip Ratio
keywords: BMI; Body composition; Frailty; Waist circumference