title: Cytomegalovirus infection in lung transplant recipients.
abstract: Cytomegalovirus (CMV) infection is a major cause of morbidity and mortality in solid organ transplant (SOT) patients. Lung transplant recipients are particularly at risk given the intense immunosuppression required. Areas covered: The Detailed review of the literature related to CMV infection, its direct and indirect effect on lung allograft function, as well as diagnosis, immune monitoring, treatment options and prevention strategies. Expert commentary: In lung transplant recipients, CMV infection is associated with pro-inflammatory and immune inhibitory effects that increase the risk of graft dysfunction and loss. Diagnosis of CMV infection remains challenging. Treatment options remain relatively limited.
authors.affiliation: a Section of Infectious Diseases, Department of Medicine , King Faisal Specialist Hospital and Research Centre , Riyadh , Saudi Arabia.
authors.forename: Reem S
authors.initials: RS
authors.lastname: Almaghrabi
authors.affiliation: a Section of Infectious Diseases, Department of Medicine , King Faisal Specialist Hospital and Research Centre , Riyadh , Saudi Arabia.
authors.forename: Ali S
authors.initials: AS
authors.lastname: Omrani
authors.affiliation: b Director Research Department , Prince Mohammed Bin Abdulaziz Hospital, Ministry of Health , Riyadh , Saudi Arabia.|c College of Medicine, Alfaisal University , Riyadh , Saudi Arabia.|d Hubert Department of Global Health, Rollins School of Public Health , Emory University , Atlanta , USA.
authors.forename: Ziad A
authors.initials: ZA
authors.lastname: Memish
mesh_terms: D003586:Cytomegalovirus Infections / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D006801:Humans; D016867:Immunocompromised Host; D016040:Lung Transplantation; D011183:Postoperative Complications / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy
keywords: CMV; Cytomegalovirus; immune compromised; lung transplant; pneumonitis