title: Pediatric Multiple Sclerosis: Distinguishing Clinical and MR Imaging Features.
abstract: This article presents an overview of evolving diagnostic criteria of pediatric multiple sclerosis and related disorders, emphasizing distinguishing clinical and neuroimaging features that should be considered for differential diagnosis in childhood and adolescence. New data on the integrity of brain tissue in children with MS provided by advanced MR imaging techniques are addressed as well.
authors.affiliation: Department of Neurology, National Pediatric Hospital Dr. Juan P. Garrahan, Combate de los Pozos 1881, Ciudad Autónoma de Buenos Aires C1436AAM, Argentina; International Pediatric MS Study Group, Foundation for Neurologic Disease, 10 State Street, Newburyport, MA 01950, USA. Electronic address: silviatenembaum@gmail.com.
authors.forename: Silvia N
authors.initials: SN
authors.lastname: Tenembaum
mesh_terms: D000293:Adolescent; D017668:Age of Onset; D002648:Child; D003711:Demyelinating Diseases / Q000276:immunology / Q000473:pathology; D003937:Diagnosis, Differential; D004673:Encephalomyelitis, Acute Disseminated / Q000276:immunology / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D009103:Multiple Sclerosis / Q000175:diagnosis / Q000276:immunology* / Q000473:pathology*; D059906:Neuroimaging / Q000379:methods*; D009471:Neuromyelitis Optica / Q000276:immunology / Q000473:pathology
keywords: Acquired demyelinating syndromes; Acute disseminated encephalomyelitis; Children; Diagnostic criteria; MR imaging; Neuromyelitis optica; Pediatric multiple sclerosis