title: REFRACTORY BRADYCARDIA--A RARE COMPLICATION OF CARBOPROST TROMETHAMINE FOR INDUCTION OF ABORTION
abstract: We report a first case of refractory several-hour sinus bradycardia, a rare but already
  described side effect of intramuscular administration of carboprost tromethamine to induce abortion
  for medical indication in a patient without cardiovascular and other diseases. After administration of
  atropine sulfate 3x0.5 mg intravenously without effect, the patient‘s sinus rhythm spontaneously
  normalized as carboprost was eliminated from the body (it has a 3-hour half-life). It is reasonable to
  believe that the specific prostaglandin underlay the etiology of bradycardia.
authors.forename: Jasna Čerkez
authors.initials: JA
authors.lastname: Habek
authors.forename: Dubravko
authors.initials: D
authors.lastname: Habek
authors.forename: Dario
authors.initials: D
authors.lastname: Gulin
mesh_terms: D000028:Abortion, Induced; D000328:Adult; D001919:Bradycardia / Q000139:chemically induced*; D002260:Carboprost / Q000009:adverse effects*; D004338:Drug Combinations; D005260:Female; D006801:Humans; D010120:Oxytocics / Q000009:adverse effects*; D011247:Pregnancy; D014325:Tromethamine / Q000009:adverse effects*
chemical_list: D004338:Drug Combinations; D010120:Oxytocics; D014325:Tromethamine; D002260:Carboprost; C062843:carboprost tromethamine