title: Respiratory Health Benefits and Risks of Living at Moderate Altitude.
abstract: Grissom, Colin K., and Barbara E. Jones. Respiratory health benefits and risks of living at moderate altitude. High Alt Med Biol 19:109-115, 2018.-The respiratory system plays a critical role in the series of physiologic responses that occur at high altitude and allows individuals to adapt to and tolerate hypobaric hypoxia. Persons with underlying lung disease may have complications, but sometimes derive benefits, related to residence at high altitude. This review will focus on health benefits and risks of patients with underlying asthma, chronic obstructive pulmonary disease, pulmonary hypertension, or obstructive sleep apnea, who live at altitudes of 1500 to 4500 m. We will also discuss maladaptive responses of the respiratory system at high altitude in previously healthy persons, including development of pulmonary hypertension and sleep-disordered breathing.
authors.affiliation: 1 Pulmonary and Critical Care Medicine, Intermountain Medical Center , Murray, Utah.|2 Pulmonary and Critical Care Medicine, The University of Utah , Salt Lake City, Utah.
authors.forename: Colin K
authors.initials: CK
authors.lastname: Grissom
authors.affiliation: 2 Pulmonary and Critical Care Medicine, The University of Utah , Salt Lake City, Utah.|3 Pulmonary and Critical Care Medicine, Salt Lake City Veterans Affairs Health System , Salt Lake City, Utah.
authors.forename: Barbara E
authors.initials: BE
authors.lastname: Jones
mesh_terms: D000064:Acclimatization / Q000502:physiology*; D000531:Altitude; D000532:Altitude Sickness / Q000209:etiology / Q000503:physiopathology; D006801:Humans; D006976:Hypertension, Pulmonary / Q000209:etiology / Q000503:physiopathology; D008171:Lung Diseases / Q000209:etiology / Q000503:physiopathology*; D012307:Risk Factors; D012891:Sleep Apnea Syndromes / Q000209:etiology / Q000503:physiopathology
keywords: asthma; chronic obstructive pulmonary disease; high altitude; obstructive sleep apnea; pulmonary hypertension