title: A Role of Cytokinin Transporter in Arabidopsis Immunity.
abstract: The phytohormone cytokinin (CK) is not only essential for plant growth and development but also impacts plant immunity. A mutant screen in a constitutively active plant immune receptor mutant snc1 (suppressor of npr1, constitutive1) identified a suppressor mutation of SNC1-induced defense responses in an ABC transporter coding gene ABCG14. ABCG14 transports CK from roots to the shoots, and the suppression of the SNC1-mediated defense response by the loss of ABCG14 is due to a deficiency of trans-zeatin (tZ)-type CK in the shoot. In addition, exogenous application of the tZ-type CK enhances disease resistance associated with increased expression of the plant immune receptor gene SNC1. Taken together, this study further established the role of tZ-type CK in disease resistance and suggests a new intersection of CKs with plant immunity at the expression regulation of a plant immune receptor gene.
authors.affiliation: 1 Plant Biology Section, School of Integrative Plant Science, Cornell University, Ithaca, New York, 14853, U.S.A.|2 College of Plant Science, Jilin University, Jilin, 130062, P.R. China; and.
authors.forename: Shuai
authors.initials: S
authors.lastname: Wang
authors.affiliation: 1 Plant Biology Section, School of Integrative Plant Science, Cornell University, Ithaca, New York, 14853, U.S.A.
authors.forename: Shu
authors.initials: S
authors.lastname: Wang
authors.affiliation: 3 Computational Biology Service Unit, Cornell University.
authors.forename: Qi
authors.initials: Q
authors.lastname: Sun
authors.affiliation: 1 Plant Biology Section, School of Integrative Plant Science, Cornell University, Ithaca, New York, 14853, U.S.A.
authors.forename: Leiyun
authors.initials: L
authors.lastname: Yang
authors.affiliation: 1 Plant Biology Section, School of Integrative Plant Science, Cornell University, Ithaca, New York, 14853, U.S.A.|4 Institute of Virology and Biotechnology, Zhejiang Academy of Agricultural Sciences, Hangzhou, Zhejiang, P.R. China.
authors.forename: Ying
authors.initials: Y
authors.lastname: Zhu
authors.affiliation: 2 College of Plant Science, Jilin University, Jilin, 130062, P.R. China; and.
authors.forename: Yaping
authors.initials: Y
authors.lastname: Yuan
authors.affiliation: 1 Plant Biology Section, School of Integrative Plant Science, Cornell University, Ithaca, New York, 14853, U.S.A.
authors.forename: Jian
authors.initials: J
authors.lastname: Hua
mesh_terms: D000070996:ATP Binding Cassette Transporter, Subfamily G / Q000235:genetics / Q000378:metabolism*; D017360:Arabidopsis / Q000235:genetics / Q000254:growth & development / Q000276:immunology* / Q000382:microbiology; D029681:Arabidopsis Proteins / Q000235:genetics / Q000378:metabolism*; D015551:Autoimmunity; D001692:Biological Transport; D003001:Cloning, Molecular; D003583:Cytokinins / Q000378:metabolism / Q000494:pharmacology; D060467:Disease Resistance; D017343:Genes, Plant; D000073658:Loss of Function Mutation / Q000235:genetics; D010641:Phenotype; D010935:Plant Diseases / Q000276:immunology / Q000382:microbiology; D057865:Plant Immunity; D013489:Suppression, Genetic
chemical_list: C000589386:ABCG14 protein, Arabidopsis; D000070996:ATP Binding Cassette Transporter, Subfamily G; D029681:Arabidopsis Proteins; D003583:Cytokinins