title: [Use of rivaroxaban in real-life treatment of venous thromboembolism: results of the TEV Survey, an Italian epidemiological study].
abstract: BACKGROUND
  Rivaroxaban is a direct and selective inhibitor of factor Xa. The randomized clinical trials EINSTEIN evaluated the efficacy and safety of rivaroxaban for the treatment of venous thromboembolism (VTE) proving that the drug was non-inferior to standard treatment. The aim of this survey was to describe how rivaroxaban was used in a group of "real-life" patients with VTE.
  
  
  METHODS
  Between June and October 2014, physicians collected aggregate data, through an online questionnaire, on consecutive patients affected by VTE and treated with rivaroxaban in the previous 6 months. Descriptive statistics were performed on the collected data.
  
  
  RESULTS
  A total of 345 questionnaires were filled out. The mean age of patients was 62 years, with a low prevalence of concomitant diseases and/or pharmacological treatments. Deep vein thrombosis was diagnosed in 90% of patients and pulmonary embolism in 47%; only 48% was hospitalized. Rivaroxaban was prescribed at the recommended doses and/or regimen in no more than 60% of cases. In 96% of patients, the initial therapeutic plan did not require changes. Adherence to the therapeutic plan and overall patient satisfaction with therapy were high.
  
  
  CONCLUSIONS
  Rivaroxaban was found easy to use and was highly appreciated by patients.
authors.affiliation: Dipartimento di Medicina (DIMED), Clinica Medica 3, Università degli Studi, Padova.
authors.forename: Raffaele
authors.initials: R
authors.lastname: Pesavento
authors.affiliation: I Medicina Interna, Centro Emostasi e Trombosi, Azienda Ospedaliera, IRCCS Arcispedale Santa Maria Nuova, Reggio Emilia.
authors.forename: Ido
authors.initials: I
authors.lastname: Iori
mesh_terms: D016021:Epidemiologic Studies; D065427:Factor Xa Inhibitors / Q000627:therapeutic use*; D005260:Female; D019538:Health Care Surveys; D006801:Humans; D007558:Italy; D008297:Male; D008875:Middle Aged; D000069552:Rivaroxaban / Q000627:therapeutic use*; D054556:Venous Thromboembolism / Q000188:drug therapy*
chemical_list: D065427:Factor Xa Inhibitors; D000069552:Rivaroxaban