title: A kaempferol triglycoside from Tephrosia preussii Taub. (Fabaceae).
abstract: A phytochemical investigation of the MeOH extract of twigs and leaves of Tephrosia preussi was carried out to give a new kaempferol triglycoside, named tephrokaempferoside (1), together with five known compounds: tephrosin (2), betulinic acid (3), lupeol (4), β-sitosterol (5) and 3-O-β-d-glucopyranoside of β-sitosterol (6). The structure of the new compound was characterised by analyses of NMR (1D and 2D) and MS data, and chemical conversion. Tephrokaempferoside (1) had weak antibacterial activity against Klebsiella pneumoniae with an MIC value of 150 μg/mL.
authors.affiliation: a Laboratory of Natural Products Chemistry, Faculty of Science, Department of Chemistry , University of Dschang , Dschang , Cameroon.
authors.forename: Yves Martial
authors.initials: YM
authors.lastname: Mba Nguekeu
authors.affiliation: a Laboratory of Natural Products Chemistry, Faculty of Science, Department of Chemistry , University of Dschang , Dschang , Cameroon.|b Institute of Natural Medicine , University of Toyama , Toyama , Japan.
authors.forename: Maurice Ducret
authors.identifier: http://orcid.org/0000-0002-4259-7103
authors.initials: MD
authors.lastname: Awouafack
authors.affiliation: a Laboratory of Natural Products Chemistry, Faculty of Science, Department of Chemistry , University of Dschang , Dschang , Cameroon.
authors.forename: Pierre
authors.initials: P
authors.lastname: Tane
authors.affiliation: a Laboratory of Natural Products Chemistry, Faculty of Science, Department of Chemistry , University of Dschang , Dschang , Cameroon.
authors.forename: Marius Roch
authors.initials: MR
authors.lastname: Nguedia Lando
authors.affiliation: b Institute of Natural Medicine , University of Toyama , Toyama , Japan.
authors.forename: Takeshi
authors.initials: T
authors.lastname: Kodama
authors.affiliation: b Institute of Natural Medicine , University of Toyama , Toyama , Japan.
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Morita
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000494:pharmacology*; D004353:Drug Evaluation, Preclinical / Q000379:methods; D006027:Glycosides / Q000737:chemistry*; D044949:Kaempferols / Q000737:chemistry*; D007711:Klebsiella pneumoniae / Q000187:drug effects; D009682:Magnetic Resonance Spectroscopy; D053978:Pentacyclic Triterpenes; D010936:Plant Extracts / Q000737:chemistry; D018515:Plant Leaves / Q000737:chemistry; D012402:Rotenone / Q000031:analogs & derivatives / Q000737:chemistry / Q000302:isolation & purification; D012855:Sitosterols / Q000737:chemistry / Q000302:isolation & purification; D031304:Tephrosia / Q000737:chemistry*; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification; D000094062:Betulinic Acid
chemical_list: D000900:Anti-Bacterial Agents; D006027:Glycosides; D044949:Kaempferols; D053978:Pentacyclic Triterpenes; D010936:Plant Extracts; D012855:Sitosterols; D014315:Triterpenes; C000625610:tephrokaempferoside; D012402:Rotenone; C025473:gamma-sitosterol; C480848:tephrosin; D000094062:Betulinic Acid
keywords: Fabaceae; Tephrosia preussii; antibacterial; kaempferol triglycoside; tephrokaempferoside