title: RF slice profile effects in magnetic resonance fingerprinting.
abstract: The radio frequency (RF) slice profile effects on T1 and T2 estimation in magnetic resonance fingerprinting (MRF) are investigated with respect to time-bandwidth product (TBW), flip angle (FA) level and field inhomogeneities. Signal evolutions are generated incorporating the non-ideal slice selective excitation process using Bloch simulation and matched to the original dictionary with and without the non-ideal slice profile taken into account. For validation, phantom and in vivo experiments are performed at 3T. Both simulations and experiments results show that T1 and T2 error from non-ideal slice profile increases with increasing FA level, off-resonance, and low TBW values. Therefore, RF slice profile effects should be compensated for accurate determination of the MR parameters.
authors.affiliation: Department of Electrical and Electronic Engineering, Yonsei University, Seoul, Republic of Korea.
authors.forename: Taehwa
authors.initials: T
authors.lastname: Hong
authors.affiliation: Department of Electrical and Electronic Engineering, Yonsei University, Seoul, Republic of Korea.
authors.forename: Dongyeob
authors.initials: D
authors.lastname: Han
authors.affiliation: Department of Electrical and Electronic Engineering, Yonsei University, Seoul, Republic of Korea.
authors.forename: Min-Oh
authors.initials: MO
authors.lastname: Kim
authors.affiliation: Department of Electrical and Electronic Engineering, Yonsei University, Seoul, Republic of Korea. Electronic address: donghyunkim@yonsei.ac.kr.
authors.forename: Dong-Hyun
authors.initials: DH
authors.lastname: Kim
mesh_terms: D001921:Brain / Q000000981:diagnostic imaging*; D003198:Computer Simulation; D064368:Healthy Volunteers; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D009682:Magnetic Resonance Spectroscopy; D019047:Phantoms, Imaging; D011846:Radio Waves; D012815:Signal Processing, Computer-Assisted; D014732:Vibration
keywords: MR fingerprinting; Quantitative imaging; Slice profile