title: Dendrobium officinaleKimura et Migo: A Review on Its Ethnopharmacology, Phytochemistry, Pharmacology, and Industrialization.
abstract: Ethnopharmacological Relevance. Dendrobii Officinalis Caulis, the stems ofDendrobium officinaleKimura et Migo, as a tonic herb in Chinese materia medica and health food in folk, has been utilized for the treatment of yin-deficiency diseases for decades.Methods. Information for analysis ofDendrobium officinaleKimura et Migo was obtained from libraries and Internet scientific databases such as PubMed, Web of Science, Google Scholar, ScienceDirect, Wiley InterScience, Ingenta, Embase, CNKI, and PubChem.Results. Over the past decades, about 190 compounds have been isolated fromDendrobium officinaleKimura et Migo. Its wide modern pharmacological actions in hepatoprotective effect, anticancer effect, hypoglycemic effect, antifatigue effect, gastric ulcer protective effect, and so on were reported. This may mainly attribute to the major and bioactive components: polysaccharides. However, other small molecule components require further study.Conclusions. Due to the lack of systematic data ofDendrobium officinale, it is important to explore its ingredient-function relationships with modern pharmacology. Recently, studies on the chemical constituents ofDendrobium officinaleconcentrated in crude polysaccharides and its structure-activity relationships remain scant. Further research is required to determine theDendrobium officinaletoxicological action and pharmacological mechanisms of other pure ingredients and crude extracts. In addition, investigation is needed for better quality control and novel drug or product development.
authors.affiliation: Zhejiang Chinese Medical University, 548 Binwen Rd., Binjiang District, Hangzhou, China.
authors.forename: Hanxiao
authors.initials: H
authors.lastname: Tang
authors.affiliation: Zhejiang Chinese Medical University, 548 Binwen Rd., Binjiang District, Hangzhou, China.
authors.forename: Tianwen
authors.initials: T
authors.lastname: Zhao
authors.affiliation: Zhejiang Chinese Medical University, 548 Binwen Rd., Binjiang District, Hangzhou, China.
authors.forename: Yunjie
authors.initials: Y
authors.lastname: Sheng
authors.affiliation: Zhejiang Chinese Medical University, 548 Binwen Rd., Binjiang District, Hangzhou, China.
authors.forename: Ting
authors.initials: T
authors.lastname: Zheng
authors.affiliation: Zhejiang Chinese Medical University, 548 Binwen Rd., Binjiang District, Hangzhou, China.
authors.forename: Lingzhu
authors.initials: L
authors.lastname: Fu
authors.affiliation: Zhejiang Chinese Medical University, 548 Binwen Rd., Binjiang District, Hangzhou, China.
authors.forename: Yongsheng
authors.identifier: 0000-0002-4984-7259
authors.initials: Y
authors.lastname: Zhang