title: Atrial fibrillation in cancer patients: Hindsight, insight and foresight.
abstract: An increase of atrial fibrillation (AF) incidence in cancer patients has recently been pointed out, with complex interrelationships between these two entities on top of surgery factors. Most of present knowledge comes from retrospective studies or data from registries but the underlying mechanisms of the association between atrial fibrillation and cancer are still unclear. An increased risk of AF in cancer patients could represent a major public health problem although scarce information is available for the challenging management of such patients with distinctive features, especially in terms of antithrombotic therapy. Elaborate evidence-based approaches are thus required. This review provides an insight into AF among cancer patients through an overview of the underlying mechanisms, epidemiology evidence and future therapeutic challenges.
authors.affiliation: Department of Medical Oncology, Lucien Neuwirth Cancer Institute, St Priest en Jarez, France. Electronic address: Benoite.mery@icloire.fr.
authors.forename: Benoîte
authors.initials: B
authors.lastname: Mery
authors.affiliation: Division of Cardiology, Jean Monnet University, Saint-Etienne, France.
authors.forename: Jean-Baptiste
authors.initials: JB
authors.lastname: Guichard
authors.affiliation: Radiotherapy Department, Lucien Neuwirth Cancer Institute, St Priest en Jarez, France.
authors.forename: Jean-Baptiste
authors.initials: JB
authors.lastname: Guy
authors.affiliation: Radiotherapy Department, Lucien Neuwirth Cancer Institute, St Priest en Jarez, France.
authors.forename: Alexis
authors.initials: A
authors.lastname: Vallard
authors.affiliation: Laboratory SNA-EPIS EA4607, Department of Physiology, University hospital of Saint-Etienne, PRES Lyon, France.
authors.forename: Jean-Claude
authors.initials: JC
authors.lastname: Barthelemy
authors.affiliation: Division of Cardiology, Jean Monnet University, Saint-Etienne, France.
authors.forename: Antoine
authors.initials: A
authors.lastname: Da Costa
authors.affiliation: Radiotherapy Department, Lucien Neuwirth Cancer Institute, St Priest en Jarez, France.
authors.forename: Nicolas
authors.initials: N
authors.lastname: Magné
authors.affiliation: Department of Vascular and Therapeutic Medicine, University Hospital of Saint-Etienne, France; INSERM, CIC1408, Saint-Etienne, France; INSERM, U1059, Vascular Dysfunction and Homeostasis, Saint-Etienne, France.
authors.forename: Laurent
authors.initials: L
authors.lastname: Bertoletti
mesh_terms: D001281:Atrial Fibrillation / Q000175:diagnosis* / Q000453:epidemiology* / Q000628:therapy; D006801:Humans; D009369:Neoplasms / Q000175:diagnosis* / Q000453:epidemiology* / Q000628:therapy; D011446:Prospective Studies; D012189:Retrospective Studies
keywords: Atrial fibrillation; Cancer patients; Onco-cardiology; Therapeutic management