title: Nanotechnology application for pain therapy.
abstract: Prolonged delivery of analgesic drugs at target sites remains a critical issue for efficient pain management. The use of nano-carriers has been reported to facilitate applicable delivery of these agents to target sites with a reduced level of systemic toxicity. Different analgesics have been loaded onto various nano carriers, including those that are natural, synthetic and copolymer, for various medical applications. In this review, we will discuss the concept of nano-formulated carriers for analgesic drugs and their impacts on the field of pain management.
authors.affiliation: a Department of Anesthesiology , Lorestan University of Medical Sciences , Khorramabad , Iran.
authors.forename: Mahmoud Reza
authors.initials: MR
authors.lastname: Moradkhani
authors.affiliation: a Department of Anesthesiology , Lorestan University of Medical Sciences , Khorramabad , Iran.
authors.forename: Arash
authors.initials: A
authors.lastname: Karimi
authors.affiliation: b Department of Medical Biotechnology , School of Advanced Technologies in Medicine, Tehran University of Medical Sciences , Tehran , Iran.
authors.forename: Babak
authors.initials: B
authors.lastname: Negahdari
mesh_terms: D000818:Animals; D000072716:Cancer Pain / Q000188:drug therapy; D006801:Humans; D008081:Liposomes; D057139:Nanofibers / Q000737:chemistry; D036103:Nanotechnology / Q000379:methods*; D059408:Pain Management / Q000379:methods*
chemical_list: D008081:Liposomes
keywords: Analgesic drugs; nano-carriers; pain; toxicity