title: [How I treat … severe beta-blocker poisoning : pharmacological approaches and ECMO].
abstract: We report the case of a woman with severe beta-blocker poisoning who, after failure of pharmacological therapy, was supported with an ECMO (ExtraCorporeal Membrane Oxygenation) device. We discuss conventional pharmacological treatments and other approaches that have emerged over the past decade such as high dose insulin therapy and lipid emulsions. Major advance has been achieved in the field of ECMO devices and their management. ECMO is now the first line device for refractory acute cardiac and/or pulmonary failure. Finally, we review the role of veno-arterial ECMO in cardiodepressive drug poisoning.
authors.affiliation: Service des Urgences, CHU de Liège, Site Sart Tilman, Liège, Belgique.
authors.forename: P
authors.initials: P
authors.lastname: Horward
authors.affiliation: Unité de Soins Intensifs Médicaux et Cardiologiques, CHU de Liège, Site Sart Tilman, Liège, Belgique.
authors.forename: B
authors.initials: B
authors.lastname: Lambermont
authors.affiliation: Service de Chirurgie Cardio-Vasculaire et Thoracique, CHU de Liège, Site Sart Tilman, Liège, Belgique.
authors.forename: J-O
authors.initials: JO
authors.lastname: Defraigne
authors.affiliation: Unité de Soins intensifs CHR de Verviers, Belgique.
authors.forename: C
authors.initials: C
authors.lastname: Gurdebeke
authors.affiliation: Service de Chirurgie Cardio-Vasculaire et Thoracique, CHU de Liège, Site Sart Tilman, Liège, Belgique.
authors.forename: P
authors.initials: P
authors.lastname: Morimont
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000506:poisoning*; D000328:Adult; D015199:Extracorporeal Membrane Oxygenation; D005260:Female; D006801:Humans; D008297:Male; D011041:Poisoning / Q000628:therapy
chemical_list: D000319:Adrenergic beta-Antagonists
keywords:  Beta;  ECMO ;  Poisoning; Cardiogenic shock ; blockers 