title: [Encapsulating peritoneal sclerosis].
abstract: BACKGROUND
  Encapsulating peritoneal sclerosis (EPS) is a complication of peritoneal dialysis (PD) with a low prevalence but high mortality. It is characterized by peritoneal inflammation and fibrosis with subsequent development of intestinal encapsulation. It is associated with a long lapse on PD, frequent episodes of peritonitis, high glucose solution use, and high peritoneal transport status.
  
  
  OBJECTIVE
  To report the clinical features of patients on PD, who developed EPS.
  
  
  METHODS
  Review of medical records of 12 patients aged 43 ± 10 years (eight women) who developed EPS.
  
  
  RESULTS
  The mean time spent on PD was 98 months. The main clinical manifestations were abdominal pain in 82% and ultrafiltration failure in 63%. In 92%, there was a history of peritonitis and 75% had high peritoneal transport at the time of diagnosis. The main findings in computed tomography were peritoneal calcification and thickening. There was a biopsy compatible with the diagnosis in 10 cases. Treatment consisted in withdrawal from PD, removal of PD catheter and the use of corticoids and tamoxifen. After withdrawal from PD 50% of patients became asymptomatic. The rest had intermittent abdominal pain and altered bowel movements. Two patients died (17%).
  
  
  CONCLUSIONS
  EPS is a serious complication of PD, which should be suspected in any patient with compatible clinical symptoms, long time on PD, multiple episodes of peritonitis and high peritoneal transport profile.
authors.affiliation: Sección de Nefrología, Departamento de Medicina, Hospital Clínico, Universidad de Chile, Santiago, Chile.
authors.forename: Rubén
authors.initials: R
authors.lastname: Torres
authors.affiliation: Sección de Nefrología, Departamento de Medicina, Hospital Clínico, Universidad de Chile, Santiago, Chile.
authors.forename: Paula
authors.initials: P
authors.lastname: Ebner
authors.affiliation: Sección de Nefrología, Departamento de Medicina, Hospital Clínico, Universidad de Chile, Santiago, Chile.
authors.forename: María Eugenia
authors.initials: ME
authors.lastname: Sanhueza
authors.affiliation: Sección de Nefrología, Departamento de Medicina, Hospital Clínico, Universidad de Chile, Santiago, Chile.
authors.forename: Miriam
authors.initials: M
authors.lastname: Alvo
authors.affiliation: Sección de Nefrología, Departamento de Medicina, Hospital Clínico, Universidad de Chile, Santiago, Chile.
authors.forename: Erico
authors.initials: E
authors.lastname: Segovia
authors.affiliation: Servicio de Anatomía Patológica, Hospital Clínico, Universidad de Chile, Santiago, Chile.
authors.forename: Paula
authors.initials: P
authors.lastname: Segura
mesh_terms: D000328:Adult; D002677:Chile; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic; D008297:Male; D008875:Middle Aged; D010530:Peritoneal Dialysis / Q000009:adverse effects*; D056627:Peritoneal Fibrosis / Q000209:etiology* / Q000473:pathology / Q000628:therapy; D010538:Peritonitis / Q000175:diagnosis* / Q000209:etiology* / Q000473:pathology / Q000628:therapy; D012189:Retrospective Studies; D012307:Risk Factors