title: Etiology and pathogenesis of Moyamoya Disease: An update on disease prevalence.
abstract: Moyamoya disease is a chronic cerebrovascular occlusive disease that is characterized by progressive stenosis of the terminal portion of the internal carotid artery and its main branches. The occurrence of Moyamoya disease is related to immune, genetic, and other factors. Though the research of Moyamoya disease has made great strides in the past 60 years, the etiology and pathogenesis are largely unknown. This review will focus on the genetic pathogenic and inflammation factors of Moyamoya disease.
authors.affiliation: Department of Neurology, The First Hospital of Jilin University, Changchun, China.
authors.forename: Shuo
authors.initials: S
authors.lastname: Huang
authors.affiliation: Department of Neurology, The First Hospital of Jilin University, Changchun, China.
authors.forename: Zhen-Ni
authors.initials: ZN
authors.lastname: Guo
authors.affiliation: Department of Neurology, The First Hospital of Jilin University, Changchun, China.
authors.forename: Mingchao
authors.initials: M
authors.lastname: Shi
authors.affiliation: Department of Neurology, The First Hospital of Jilin University, Changchun, China.
authors.forename: Yi
authors.initials: Y
authors.lastname: Yang
authors.affiliation: Department of Neurology, The First Hospital of Jilin University, Changchun, China.
authors.forename: Mingli
authors.initials: M
authors.lastname: Rao
mesh_terms: D000818:Animals; D006801:Humans; D009072:Moyamoya Disease / Q000453:epidemiology* / Q000209:etiology* / Q000235:genetics / Q000276:immunology; D015995:Prevalence
keywords: Moyamoya disease; epidemiology; immunology; pathogenesis