title: A Literature Revision in Primary Cutaneous B-cell Lymphoma.
abstract: The term "Primary Cutaneous B-Cell Lymphoma" (PCBCL) comprehends a variety of lymphoproliferative disorders characterized by a clonal proliferation of B-cells primarily involving the skin. The absence of evident extra-cutaneous disease must be confirmed after six-month follow-up in order to exclude a nodal non-Hodgkin's lymphoma (NHL) with secondary cutaneous involvement, which may have a completely different clinical behavior and prognosis. In this article, we have summarized the clinico-pathological features of main types of PCBCL and we outline the guidelines for management based on a review of the available literature.
authors.affiliation: Department of Medical Sciences, Dermatologic Clinic, University of Turin, Turin, Italy.
authors.forename: R La
authors.initials: R
authors.lastname: Selva
authors.affiliation: UOC Dermatologia, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
authors.forename: S Alberti
authors.initials: SA
authors.lastname: Violetti
authors.affiliation: Department of Surgery and Translational Medicine, Section of Dermatology and Venereology, University of Florence Medical School, Florence, Italy.
authors.forename: C
authors.initials: C
authors.lastname: Delfino
authors.affiliation: Department of Surgery and Translational Medicine, Section of Dermatology and Venereology, University of Florence Medical School, Florence, Italy.
authors.forename: V
authors.initials: V
authors.lastname: Grandi
authors.affiliation: Department of Medical Sciences, Dermatologic Clinic, University of Turin, Turin, Italy.
authors.forename: S
authors.initials: S
authors.lastname: Cicchelli
authors.affiliation: Department of Medical Sciences, Dermatologic Clinic, University of Turin, Turin, Italy.
authors.forename: C
authors.initials: C
authors.lastname: Tomasini
authors.affiliation: Department of Medical Sciences, Dermatologic Clinic, University of Turin, Turin, Italy.
authors.forename: M T
authors.initials: MT
authors.lastname: Fierro
authors.affiliation: University of Milano-Bicocca, Milan, Italy.
authors.forename: E
authors.initials: E
authors.lastname: Berti
authors.affiliation: Department of Surgery and Translational Medicine, Section of Dermatology and Venereology, University of Florence Medical School, Florence, Italy.
authors.forename: N
authors.initials: N
authors.lastname: Pimpinelli
authors.affiliation: Department of Medical Sciences, Dermatologic Clinic, University of Turin, Turin, Italy.
authors.forename: P
authors.initials: P
authors.lastname: Quaglino
keywords: Cutaneous B-cell lymphoma; Primary Cutaneous Diffuse Large B cell Lymphoma other; Primary Cutaneous Marginal zone Lymphoma; Primary cutaneous diffuse large B-cell lymphoma leg type; Primary cutaneous follicle-center lymphoma