title: Brown Fat-Derived Exosomes: Small Vesicles with Big Impact.
abstract: Adipose tissue (AT) not only stores energy, but also secretes hormones and releases small vesicles known as exosomes. Thomou et al. (2017) now show that exosomes secreted by brown fat carry miRNAs that regulate the liver. Thus, AT exosomes might have therapeutic and diagnostic relevance for metabolic disorders.
authors.affiliation: Institute of Pharmacology and Toxicology, University of Bonn, 53127 Bonn, Germany.
authors.forename: Yong
authors.initials: Y
authors.lastname: Chen
authors.affiliation: Institute of Pharmacology and Toxicology, University of Bonn, 53127 Bonn, Germany. Electronic address: alexander.pfeifer@uni-bonn.de.
authors.forename: Alexander
authors.initials: A
authors.lastname: Pfeifer
mesh_terms: D002001:Adipose Tissue, Brown; D055354:Exosomes; D006801:Humans; D008099:Liver; D008659:Metabolic Diseases; D035683:MicroRNAs
chemical_list: D035683:MicroRNAs
keywords: FGF21; biomarker; brown adipose tissue; exosomes; liver; microRNAs; white adipose tissue