title: IMGMD: A platform for the integration and standardisation of In silico Microbial Genome-scale Metabolic Models.
abstract: Genome-scale metabolic models (GSMMs) constitute a platform that combines genome sequences and detailed biochemical information to quantify microbial physiology at the system level. To improve the unity, integrity, correctness, and format of data in published GSMMs, a consensus IMGMD database was built in the LAMP (Linux + Apache + MySQL + PHP) system by integrating and standardizing 328 GSMMs constructed for 139 microorganisms. The IMGMD database can help microbial researchers download manually curated GSMMs, rapidly reconstruct standard GSMMs, design pathways, and identify metabolic targets for strategies on strain improvement. Moreover, the IMGMD database facilitates the integration of wet-lab and in silico data to gain an additional insight into microbial physiology. The IMGMD database is freely available, without any registration requirements, at http://imgmd.jiangnan.edu.cn/database.
authors.affiliation: State Key Laboratory of Food Science and Technology, Jiangnan University, 1800 Lihu Road, Wuxi, Jiangsu, 214122, China.|The Key Laboratory of Industrial Biotechnology, Ministry of Education, Jiangnan University, 1800 Lihu Road, Wuxi, Jiangsu, 214122, China.
authors.forename: Chao
authors.initials: C
authors.lastname: Ye
authors.affiliation: State Key Laboratory of Food Science and Technology, Jiangnan University, 1800 Lihu Road, Wuxi, Jiangsu, 214122, China.|The Key Laboratory of Industrial Biotechnology, Ministry of Education, Jiangnan University, 1800 Lihu Road, Wuxi, Jiangsu, 214122, China.
authors.forename: Nan
authors.initials: N
authors.lastname: Xu
authors.affiliation: Key Laboratory for Neuroinformation of Ministry of Education, University of Electronic Science and Technology of China, No. 4, 2nd Section, North Jianshe Road, Chengdu, Sichuan, 610054, China.
authors.forename: Chuan
authors.initials: C
authors.lastname: Dong
authors.affiliation: School of Biology and Engineering, Guizhou Medical University, Dongqing Road, Huaxi District, Guiyang, Guizhou, 550025, China.|School of Big Health, Guizhou Medical University, Dongqing Road, Huaxi District, Guiyang, Guizhou, 550025, China.
authors.forename: Yuannong
authors.initials: Y
authors.lastname: Ye
authors.affiliation: State Key Laboratory of Food Science and Technology, Jiangnan University, 1800 Lihu Road, Wuxi, Jiangsu, 214122, China.|The Key Laboratory of Industrial Biotechnology, Ministry of Education, Jiangnan University, 1800 Lihu Road, Wuxi, Jiangsu, 214122, China.
authors.forename: Xuan
authors.initials: X
authors.lastname: Zou
authors.affiliation: State Key Laboratory of Food Science and Technology, Jiangnan University, 1800 Lihu Road, Wuxi, Jiangsu, 214122, China.|The Key Laboratory of Industrial Biotechnology, Ministry of Education, Jiangnan University, 1800 Lihu Road, Wuxi, Jiangsu, 214122, China.
authors.forename: Xiulai
authors.initials: X
authors.lastname: Chen
authors.affiliation: Key Laboratory for Neuroinformation of Ministry of Education, University of Electronic Science and Technology of China, No. 4, 2nd Section, North Jianshe Road, Chengdu, Sichuan, 610054, China.
authors.forename: Fengbiao
authors.initials: F
authors.lastname: Guo
authors.affiliation: State Key Laboratory of Food Science and Technology, Jiangnan University, 1800 Lihu Road, Wuxi, Jiangsu, 214122, China. mingll@jiangnan.edu.cn.|The Key Laboratory of Industrial Biotechnology, Ministry of Education, Jiangnan University, 1800 Lihu Road, Wuxi, Jiangsu, 214122, China. mingll@jiangnan.edu.cn.
authors.forename: Liming
authors.initials: L
authors.lastname: Liu
mesh_terms: D019295:Computational Biology / Q000379:methods*; D016208:Databases, Factual; D004734:Energy Metabolism; D064349:Genome, Microbial; D023281:Genomics / Q000379:methods; D055432:Metabolomics; D008829:Microbiology; D008954:Models, Biological; D012984:Software; D014584:User-Computer Interface; D064878:Web Browser