title: Effects of High-Intensity Interval Training on Aerobic Capacity in Cardiac Patients: A Systematic Review with Meta-Analysis.
abstract: Purpose. The aim of this study was to compare the effects of high-intensity interval training (INTERVAL) and moderate-intensity continuous training (CONTINUOUS) on aerobic capacity in cardiac patients.Methods. A meta-analysis identified by searching the PubMed, Cochrane Library, EMBASE, and Web of Science databases from inception through December 2016 compared the effects of INTERVAL and CONTINUOUS among cardiac patients.Results. Twenty-one studies involving 736 participants with cardiac diseases were included. Compared with CONTINUOUS, INTERVAL was associated with greater improvement in peak VO2(mean difference 1.76 mL/kg/min, 95% confidence interval 1.06 to 2.46 mL/kg/min,p< 0.001) and VO2at AT (mean difference 0.90 mL/kg/min, 95% confidence interval 0.0 to 1.72 mL/kg/min,p= 0.03). No significant difference between the INTERVAL and CONTINUOUS groups was observed in terms of peak heart rate, peak minute ventilation, VE/VCO2slope and respiratory exchange ratio, body mass, systolic or diastolic blood pressure, triglyceride or low- or high-density lipoprotein cholesterol level, flow-mediated dilation, or left ventricular ejection fraction.Conclusions. This study showed that INTERVAL improves aerobic capacity more effectively than does CONTINUOUS in cardiac patients. Further studies with larger samples are needed to confirm our observations.
authors.affiliation: Department of Cardiology, First Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong 515041, China.
authors.forename: Bin
authors.initials: B
authors.lastname: Xie
authors.affiliation: Department of Cardiology, First Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong 515041, China.
authors.forename: Xianfeng
authors.initials: X
authors.lastname: Yan
authors.affiliation: Department of Plastic Surgery, First Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong 515041, China.
authors.forename: Xiangna
authors.identifier: 0000-0002-9750-7742
authors.initials: X
authors.lastname: Cai
authors.affiliation: Department of Cardiology, First Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong 515041, China.
authors.forename: Jilin
authors.identifier: 0000-0003-3312-5478
authors.initials: J
authors.lastname: Li
mesh_terms: D001794:Blood Pressure; D017079:Exercise Tolerance; D006333:Heart Failure / Q000097:blood / Q000503:physiopathology / Q000628:therapy*; D006339:Heart Rate; D000072696:High-Intensity Interval Training; D006801:Humans; D008075:Lipoproteins, HDL / Q000097:blood; D010101:Oxygen Consumption; D014280:Triglycerides / Q000097:blood; D016277:Ventricular Function, Left / Q000502:physiology*
chemical_list: D008075:Lipoproteins, HDL; D014280:Triglycerides