title: Performance Observations of Scanner Qualification of NCI-Designated Cancer Centers: Results From the Centers of Quantitative Imaging Excellence (CQIE) Program.
abstract: We present an overview of the Centers for Quantitative Imaging Excellence (CQIE) program, which was initiated in 2010 to establish a resource of clinical trial-ready sites within the National Cancer Institute (NCI)-designated Cancer Centers (NCI-CCs) network. The intent was to enable imaging centers in the NCI-CCs network capable of conducting treatment trials with advanced quantitative imaging end points. We describe the motivations for establishing the CQIE, the process used to initiate the network, the methods of site qualification for positron emission tomography, computed tomography, and magnetic resonance imaging, and the results of the evaluations over the subsequent 3 years.
authors.affiliation: Department of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania.
authors.forename: Mark
authors.initials: M
authors.lastname: Rosen
authors.affiliation: Department of Radiology, University of Washington, Seattle Washington.
authors.forename: Paul E
authors.initials: PE
authors.lastname: Kinahan
authors.affiliation: Center for Research and Innovation, American College of Radiology, Philadelphia, Pennsylvania. Electronic address: jgimpel@acr.org.
authors.forename: James F
authors.initials: JF
authors.lastname: Gimpel
authors.affiliation: Center for Research and Innovation, American College of Radiology, Philadelphia, Pennsylvania.
authors.forename: Adam
authors.initials: A
authors.lastname: Opanowski
authors.affiliation: Mallinckrodt Institute of Radiology and the Siteman Cancer Center, Washington University School of Medicine, St. Louis, Missouri.
authors.forename: Barry A
authors.initials: BA
authors.lastname: Siegel
authors.affiliation: Cancer Imaging Program, Leidos Biomedical, Frederick National Laboratory for Cancer Research, Frederick, Maryland.
authors.forename: G Craig
authors.initials: GC
authors.lastname: Hill
authors.affiliation: Office of Cancer Centers, National Cancer Institute, Bethesda, Maryland.
authors.forename: Linda
authors.initials: L
authors.lastname: Weiss
authors.affiliation: Cancer Imaging Program, National Cancer Institute, Bethesda, Maryland.
authors.forename: Lalitha
authors.initials: L
authors.lastname: Shankar
mesh_terms: D002173:Cancer Care Facilities / Q000592:standards; D002986:Clinical Trials as Topic / Q000592:standards; D004867:Equipment Design; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000592:standards*; D054547:National Cancer Institute (U.S.); D009369:Neoplasms / Q000175:diagnosis* / Q000628:therapy; D019047:Phantoms, Imaging; D049268:Positron-Emission Tomography / Q000592:standards*; D014057:Tomography, X-Ray Computed / Q000592:standards*; D014481:United States
keywords: Scanner qualification; cancer imaging; clinical trials; imaging accreditation; imaging credentialing; phantom imaging