title: First experience of drug-coated balloons for treatment of bioresorbable vascular scaffold restenosis.
abstract: OBJECTIVE
  The aim of this study is to evaluate the role of drug-coated balloons (DCB) for the management of bioresorbable vascular scaffold (BVS) restenosis.
  
  
  RESULTS
  In a series of 25 BVS restenosis discovered during systematic angiographic follow up of 246 consecutive BVS implantations at our institution, DCB was used as a primary therapeutic tool in 9 patients and 3 different types of DCB were used. Follow-up coronary angiography at 12months after DCB treatment was performed to all the patients. Among the 9 patients treated with DCB, angiographic follow up revealed failure in two patients that experienced type III restenosis (both of them treated with the same type of DCB). Both patients were treated with drug eluting stent implantation.
  
  
  CONCLUSIONS
  In this case series of consecutive patients with BVS restenosis, the use of certain types of DCB is safe and effective in order to maintain vessel patency at mid-term follow up. Despite the small sample size and the study limitations, DCB can provide therefore an alternative treatment option in this setting, avoiding the implantation of further metallic stents in a patient where a different strategy was initially planned.
authors.affiliation: Interventional Cardiology, ASST Fatebenefratelli-Sacco, Milano, Italy; Faculty of Medicine, University of Alexandria, Egypt.
authors.forename: Mostafa
authors.initials: M
authors.lastname: Elwany
authors.affiliation: Interventional Cardiology, ASST Fatebenefratelli-Sacco, Milano, Italy.
authors.forename: Roberto Adriano
authors.initials: RA
authors.lastname: Latini
authors.affiliation: Interventional Cardiology, ASST Fatebenefratelli-Sacco, Milano, Italy.
authors.forename: Gaetano
authors.initials: G
authors.lastname: Di Palma
authors.affiliation: Interventional Cardiology, ASST Fatebenefratelli-Sacco, Milano, Italy.
authors.forename: Pedro Silva
authors.initials: PS
authors.lastname: Orrego
authors.affiliation: Interventional Cardiology, ASST Fatebenefratelli-Sacco, Milano, Italy; Fondazione G. Monasterio CNR-Regione Toscana, Pisa, Massa, Italy. Electronic address: bcortese@gmail.com.
authors.forename: Bernardo
authors.initials: B
authors.lastname: Cortese
mesh_terms: D020341:Absorbable Implants; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002317:Cardiovascular Agents / Q000008:administration & dosage* / Q000009:adverse effects; D020099:Coated Materials, Biocompatible; D017023:Coronary Angiography; D023903:Coronary Restenosis / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000628:therapy*; D023921:Coronary Stenosis / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000628:therapy*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D062645:Percutaneous Coronary Intervention / Q000009:adverse effects / Q000295:instrumentation*; D011474:Prosthesis Design; D013997:Time Factors; D016896:Treatment Outcome; D062666:Vascular Access Devices; D014654:Vascular Patency
chemical_list: D002317:Cardiovascular Agents; D020099:Coated Materials, Biocompatible
keywords: Bioresorbable vascular scaffold (BVS); Drug coated balloons (DCB); In-scaffold restenosis