title: The Resection of Thyroid Cancer Was Associated with the Resolution of Hyporesponsiveness to an Erythropoiesis-stimulating Agent in a Hemodialysis Patient with Aceruloplasminemia.
abstract: We herein report the case of a hemodialysis patient whose response to an erythropoiesis-stimulating agent (ESA) improved following the resection of thyroid cancer. Her hemoglobin level remained below 7 g/dL, despite the use of ESA. During the search for the causes of her hyporesponsiveness to ESA, papillary thyroid cancer and aceruloplasminemia were found. The existence of other potential causes, such as iron deficiency, infectious disease, severe hyperparathyroidism and malnutrition were ruled out. Following the resection of the thyroid cancer tumor, her hemoglobin level increased to 10.2 g/dL over a period of 4 months. This is the first report to demonstrate the resolution of hyporesponsiveness to ESA following the resection of a malignant tumor.
authors.affiliation: Department of Medicine, Yaizu City Hospital, Japan.
authors.forename: Soichiro
authors.initials: S
authors.lastname: Nagata
authors.forename: Naoki
authors.initials: N
authors.lastname: Ikegaya
authors.forename: Shuhei
authors.initials: S
authors.lastname: Ogino
authors.forename: Shinichi
authors.initials: S
authors.lastname: Uchida
authors.forename: Mikiko
authors.initials: M
authors.lastname: Itaya
authors.forename: Aoi
authors.initials: A
authors.lastname: Momita
authors.forename: Shingo
authors.initials: S
authors.lastname: Shinozaki
authors.forename: Masaharu
authors.initials: M
authors.lastname: Ohura
authors.forename: Ken
authors.initials: K
authors.lastname: Kuriki
authors.forename: Satoshi
authors.initials: S
authors.lastname: Kono
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Miyajima
authors.forename: Akira
authors.initials: A
authors.lastname: Hishida
mesh_terms: D000740:Anemia / Q000209:etiology; D002277:Carcinoma / Q000150:complications* / Q000175:diagnosis / Q000601:surgery*; D002291:Carcinoma, Papillary; D002570:Ceruloplasmin / Q000172:deficiency*; D005260:Female; D006397:Hematinics / Q000008:administration & dosage / Q000627:therapeutic use*; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D019189:Iron Metabolism Disorders / Q000150:complications*; D008875:Middle Aged; D019636:Neurodegenerative Diseases / Q000150:complications*; D006435:Renal Dialysis; D000077273:Thyroid Cancer, Papillary; D013964:Thyroid Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000601:surgery*
chemical_list: D006397:Hematinics; D006454:Hemoglobins; D002570:Ceruloplasmin