title: Breast and pleuropulmonary metastasis of multirecurrent scalp dermatofibrosarcoma protuberans: a case report.
abstract: BACKGROUND
  Dermatofibrosarcoma protuberans is a rare tumor, representing about 0.1% of skin malignant tumors. It is characterized by local aggressiveness with significant potential for recurrence. Although metastasis is rare, it does occur. We report a case of a Burkinabe woman with dermatofibrosarcoma protuberans.
  
  
  METHODS
  A 27-year-old Burkinabe woman consulted our institution for a recurrent scalp nodule that had been evolving for 13 years. At clinical examination, she was in good condition with a dry cough. An atrophic scarring alopecic plaque of 15-cm diameter in the right parietal region of the scalp, topped by an erythematous firm nodule measuring 3 × 2 × 2 cm, was noted, as well as a mobile nodule located in the axillary tail of the right breast. Cerebral computed tomodensitometry had not objectified the reach of the vault or the brain. A thoracic scan revealed four intrathoracic tissue masses straight to pleural touch. There were no evolutionary lesions in the abdominopelvic region. Histopathologic examination of the biopsy of the scalp nodule showed a proliferation of fibrous background, with fusiform cells carrying a storiform appearance. These cells had dark, elongated nuclei and showed some mitosis without atypia. The cells expressed CD34 intensely and diffusely. The test results were negative for PS100 and smooth muscle actin. The breast nodule showed the same profile as the scalp nodule.
  
  
  CONCLUSIONS
  We concluded on the diagnosis of scalp dermatofibrosarcoma protuberans with breast metastasis and probable pleuropulmonary metastasis.
authors.affiliation: Hôpital de District de Bogodogo, Service de Radiologie et d'Imagerie Médicale, Ouagadougou, Burkina Faso. ninawed@hotmail.com.|Unité de Recherche en Sciences de la Santé, Université Ouaga I Professeur Joseph Ki-Zerbo, Ouagadougou, Burkina Faso. ninawed@hotmail.com.
authors.forename: N-A
authors.initials: NA
authors.lastname: Ouédraogo Nde
authors.affiliation: Unité de Recherche en Sciences de la Santé, Université Ouaga I Professeur Joseph Ki-Zerbo, Ouagadougou, Burkina Faso.|Service de Dermatologie, Centre Raoul Follereau, Ouagadougou, Burkina Faso.
authors.forename: N A
authors.initials: NA
authors.lastname: Ouédraogo
authors.affiliation: Unité de Recherche en Sciences de la Santé, Université Ouaga I Professeur Joseph Ki-Zerbo, Ouagadougou, Burkina Faso.|Service d'Oncologie Médicale, Centre Hospitalier Universitaire Yalgado Ouedraogo, Ouagadougou, Burkina Faso.
authors.forename: H A
authors.initials: HA
authors.lastname: Bambara
authors.affiliation: Hôpital de District de Bogodogo, Service de Radiologie et d'Imagerie Médicale, Ouagadougou, Burkina Faso.|Unité de Recherche en Sciences de la Santé, Université Ouaga I Professeur Joseph Ki-Zerbo, Ouagadougou, Burkina Faso.
authors.forename: B M A
authors.initials: BM
authors.lastname: Tiemtoré-Kambou
authors.affiliation: Service de Dermatologie, Centre Hospitalier Régional Ouahigouya, Ouagadougou, Burkina Faso.
authors.forename: F
authors.initials: F
authors.lastname: Traoré
authors.affiliation: Unité de Recherche en Sciences de la Santé, Université Ouaga I Professeur Joseph Ki-Zerbo, Ouagadougou, Burkina Faso.|Service de chirurgie viscérale et oncologique, Centre Hospitalier Universitaire Yalgado Ouedraogo, Ouagadougou, Burkina Faso.
authors.forename: N
authors.initials: N
authors.lastname: Zongo
authors.affiliation: Unité de Recherche en Sciences de la Santé, Université Ouaga I Professeur Joseph Ki-Zerbo, Ouagadougou, Burkina Faso.|Service de Dermatologie, Centre Hospitalier Universitaire Yalgado Ouedraogo, Ouagadougou, Burkina Faso.
authors.forename: M S
authors.initials: MS
authors.lastname: Ouédraogo
authors.affiliation: Unité de Recherche en Sciences de la Santé, Université Ouaga I Professeur Joseph Ki-Zerbo, Ouagadougou, Burkina Faso.|Service de Dermatologie, Centre Hospitalier Universitaire Yalgado Ouedraogo, Ouagadougou, Burkina Faso.
authors.forename: G P
authors.initials: GP
authors.lastname: Tapsoba
authors.affiliation: Laboratoire d'Anatomie Pathologie et de Cytologie à Monastir, Monastir, Tunisia.
authors.forename: Achach
authors.initials: A
authors.lastname: Thouraya Chtioui
authors.affiliation: Unité de Recherche en Sciences de la Santé, Université Ouaga I Professeur Joseph Ki-Zerbo, Ouagadougou, Burkina Faso.|Service d'Anatomopathologie, Centre Hospitalier Universitaire Yalgado Ouedraogo, Ouagadougou, Burkina Faso.
authors.forename: A
authors.initials: A
authors.lastname: Lamien/Sanou
mesh_terms: D000328:Adult; D000505:Alopecia / Q000473:pathology; D018952:Antigens, CD34 / Q000378:metabolism; D000970:Antineoplastic Agents / Q000627:therapeutic use; D001706:Biopsy; D001943:Breast Neoplasms / Q000473:pathology / Q000556:secondary*; D003371:Cough / Q000209:etiology; D018223:Dermatofibrosarcoma / Q000473:pathology* / Q000628:therapy; D005260:Female; D006801:Humans; D000068877:Imatinib Mesylate / Q000627:therapeutic use; D008175:Lung Neoplasms / Q000473:pathology / Q000556:secondary*; D009364:Neoplasm Recurrence, Local / Q000473:pathology*; D010997:Pleural Neoplasms / Q000473:pathology / Q000556:secondary*; D011379:Prognosis; D012535:Scalp / Q000473:pathology*; D012878:Skin Neoplasms / Q000473:pathology* / Q000628:therapy; D016896:Treatment Outcome
chemical_list: D018952:Antigens, CD34; D000970:Antineoplastic Agents; D000068877:Imatinib Mesylate
keywords: Breast; Burkina Faso; Metastasis; Pleuropulmonary; Secondary location