title: Role of Quantitative Wall Motion Analysis in Patients with Acute Chest Pain at Emergency Department.
abstract: BACKGROUND
  Evaluation of acute chest pain in emergency department (ED), using limited resource and time, is still very difficult despite recent development of many diagnostic tools. In this study, we tried to determine the applicability of new semi-automated cardiac function analysis tool, velocity vector imaging (VVI), in the evaluation of the patients with acute chest pain in ED.
  
  
  METHODS
  We prospectively enrolled 48 patients, who visited ED with acute chest pain, and store images to analyze VVI from July 2005 to July 2007.
  
  
  RESULTS
  In 677 of 768 segments (88%), the analysis by VVI was feasible among 48 patients. Peak systolic radial velocity (Vpeak) and strain significantly decreased according to visual regional wall motion abnormality (Vpeak, 3.50 ± 1.34 cm/s for normal vs. 3.46 ± 1.52 cm/s for hypokinesia, 2.51 ± 1.26 for akinesia,p< 0.01; peak systolic radial strain -31.74 ± 9.15% fornormal, -24.33 ± 6.28% for hypokinesia, -20.30 ± 7.78% for akinesia,p< 0.01). However, the velocity vectors at the time of mitral valve opening (MVO) were directed outward in the visually normal myocardium, inward velocity vectors were revealed in the visually akinetic area (VMVO, -0.85 ± 1.65 cm/s for normal vs. 0.10 ± 1.46 cm/s for akinesia,p< 0.001). At coronary angiography, VMVOclearly increased in the ischemic area (VMVO, -0.88+1.56 cm/s for normal vs. 0.70 + 2.04 cm/s for ischemic area,p< 0.01).
  
  
  CONCLUSIONS
  Regional wall motion assessment using VVI showed could be used to detect significant ischemia in the patient with acute chest pain at ED.
authors.affiliation: Division of Cardiology, Department of Internal Medicine, Sejong General Hospital, Bucheon, Korea.
authors.forename: Kyung-Hee
authors.initials: KH
authors.lastname: Kim
authors.affiliation: Division of Cardiology, Department of internal Medicine, Seoul National University College of Medicine, Seoul National University Hospital, Seoul, Korea.; Institute on Aging, Seoul National University, Seoul, Korea.
authors.forename: Sang-Hoon
authors.initials: SH
authors.lastname: Na
authors.affiliation: Division of Cardiology, Department of Internal Medicine, Sejong General Hospital, Bucheon, Korea.
authors.forename: Jin-Sik
authors.initials: JS
authors.lastname: Park
keywords: Chest pain; Emergency department; Velocity vector imaging; Wall motion abnormality