title: Costs of treatment of adult patients with cystic fibrosis in Poland and internationally.
abstract: OBJECTIVE
  Despite its low prevalence, cystic fibrosis (CF) may have a considerable impact on healthcare system expenditures in terms of direct healthcare costs and lost productivity. This study was aimed at calculation of costs associated with CF treatment in Poland, as well as at comparison of average costs of treatment of CF patients in selected countries, taking into account the purchasing power parity.
  
  
  METHODS
  Retrospective study.
  
  
  METHODS
  The researchers undertook a retrospective study of adult patients with CF taking into account the broadest social perspective possible. Medical and non-medical direct costs as well as indirect costs were calculated. CF costs estimated by researchers from other countries over the last 15 years were also compared.
  
  
  RESULTS
  Total annual treatment cost per one CF patient in Poland was on average EUR 19,581.08. Costs of treatment of CF patients over the last 15 years varied between the countries and ranged from EUR 23,330.82 in Bulgaria to EUR 68,696.42 in the United States.
  
  
  CONCLUSIONS
  CF is an international problem. The data in this study could be the baseline for integrated and harmonised approaches for periodical assessment of the future impact of new public policies and interventions for rare diseases at the national and international levels.
authors.affiliation: Department of Pharmacoeconomics and Social Pharmacy, Poznań University of Medical Sciences, Dąbrowskiego 79 St., 60-529 Poznań, Poland. Electronic address: dorota.kol@vp.pl.
authors.forename: Dorota
authors.initials: D
authors.lastname: Kopciuch
authors.affiliation: Department of Pharmacoeconomics and Social Pharmacy, Poznań University of Medical Sciences, Dąbrowskiego 79 St., 60-529 Poznań, Poland.
authors.forename: Tomasz
authors.initials: T
authors.lastname: Zaprutko
authors.affiliation: Department of Pharmacoeconomics and Social Pharmacy, Poznań University of Medical Sciences, Dąbrowskiego 79 St., 60-529 Poznań, Poland.
authors.forename: Anna
authors.initials: A
authors.lastname: Paczkowska
authors.affiliation: Department of Pharmacoeconomics and Social Pharmacy, Poznań University of Medical Sciences, Dąbrowskiego 79 St., 60-529 Poznań, Poland.
authors.forename: Elżbieta
authors.initials: E
authors.lastname: Nowakowska
mesh_terms: D000328:Adult; D017281:Cost of Illness; D003550:Cystic Fibrosis / Q000191:economics* / Q000628:therapy*; D005260:Female; D017048:Health Care Costs / Q000706:statistics & numerical data*; D006801:Humans; D038622:Internationality; D008297:Male; D011044:Poland; D012189:Retrospective Studies
keywords: Comparison of costs; Costs and costs analysis; Cystic fibrosis; Economic burden; Social impact of cystic fibrosis