title: Disseminated superficial actinic porokeratosis treated with ingenol mebutate gel 0.05.
abstract: Disseminated superficial actinic porokeratosis (DSAP) is a chronic condition characterized by numerous atrophic papules and patches with a distinctive peripheral keratotic ridge, typically found on sun-exposed areas. Treatment of DSAP is warranted not only for cosmetic and symptomatic benefits but also to prevent malignant transformation. Successful treatment of DSAP often is difficult and frequently requires the use of multiple modalities. Ingenol mebutate gel 0.05% is a topical medication primarily used for the treatment of actinic keratosis (AK) by inducing cell death. We report a case of DSAP treated effectively with ingenol mebutate gel 0.05%.
authors.affiliation: McGill University, Montreal, Quebec, Canada.
authors.forename: Isabella
authors.initials: I
authors.lastname: Anderson
authors.affiliation: Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
authors.forename: Ethan T
authors.initials: ET
authors.lastname: Routt
authors.affiliation: Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
authors.forename: Shelbi C
authors.initials: SC
authors.lastname: Jim On
mesh_terms: D000279:Administration, Cutaneous; D000328:Adult; D003879:Dermatologic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D004224:Diterpenes / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D005782:Gels; D006801:Humans; D017499:Porokeratosis / Q000188:drug therapy* / Q000473:pathology; D016896:Treatment Outcome
chemical_list: C486592:3-ingenyl angelate; D003879:Dermatologic Agents; D004224:Diterpenes; D005782:Gels