title: TIN-X: target importance and novelty explorer.
abstract: BACKGROUND
  The increasing amount of peer-reviewed manuscripts requires the development of specific mining tools to facilitate the visual exploration of evidence linking diseases and proteins.
  
  
  RESULTS
  We developed TIN-X, the Target Importance and Novelty eXplorer, to visualize the association between proteins and diseases, based on text mining data processed from scientific literature. In the current implementation, TIN-X supports exploration of data for G-protein coupled receptors, kinases, ion channels, and nuclear receptors. TIN-X supports browsing and navigating across proteins and diseases based on ontology classes, and displays a scatter plot with two proposed new bibliometric statistics: Importance and Novelty.
  
  
  METHODS
  http://www.newdrugtargets.org.
  
  
  BACKGROUND
  cbologa@salud.unm.edu.
authors.affiliation: Translational Informatics Division, Department of Internal Medicine, University of New Mexico School of Medicine, Albuquerque, NM 87131, USA.
authors.forename: Daniel C
authors.initials: DC
authors.lastname: Cannon
authors.affiliation: Translational Informatics Division, Department of Internal Medicine, University of New Mexico School of Medicine, Albuquerque, NM 87131, USA.
authors.forename: Jeremy J
authors.initials: JJ
authors.lastname: Yang
authors.affiliation: Translational Informatics Division, Department of Internal Medicine, University of New Mexico School of Medicine, Albuquerque, NM 87131, USA.
authors.forename: Stephen L
authors.initials: SL
authors.lastname: Mathias
authors.affiliation: Translational Informatics Division, Department of Internal Medicine, University of New Mexico School of Medicine, Albuquerque, NM 87131, USA.
authors.forename: Oleg
authors.initials: O
authors.lastname: Ursu
authors.affiliation: Translational Informatics Division, Department of Internal Medicine, University of New Mexico School of Medicine, Albuquerque, NM 87131, USA.
authors.forename: Subramani
authors.initials: S
authors.lastname: Mani
authors.affiliation: UNM Center for Molecular Discovery, University of New Mexico Comprehensive Cancer Center, University of New Mexico, Albuquerque, NM 87131, USA.
authors.forename: Anna
authors.initials: A
authors.lastname: Waller
authors.affiliation: Department of Molecular and Cellular Pharmacology, Miller School of Medicine, University of Miami, Miami, FL 33136, USA.
authors.forename: Stephan C
authors.initials: SC
authors.lastname: Schürer
authors.affiliation: Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen N 2200, Denmark.
authors.forename: Lars Juhl
authors.initials: LJ
authors.lastname: Jensen
authors.affiliation: UNM Center for Molecular Discovery, University of New Mexico Comprehensive Cancer Center, University of New Mexico, Albuquerque, NM 87131, USA.|Department of Pathology, University of New Mexico, NM 87131, USA.
authors.forename: Larry A
authors.initials: LA
authors.lastname: Sklar
authors.affiliation: Translational Informatics Division, Department of Internal Medicine, University of New Mexico School of Medicine, Albuquerque, NM 87131, USA.
authors.forename: Cristian G
authors.initials: CG
authors.lastname: Bologa
authors.affiliation: Translational Informatics Division, Department of Internal Medicine, University of New Mexico School of Medicine, Albuquerque, NM 87131, USA.
authors.forename: Tudor I
authors.initials: TI
authors.lastname: Oprea
mesh_terms: D064229:Biological Ontologies; D003196:Computer Graphics; D057225:Data Mining / Q000379:methods*; D004194:Disease / Q000209:etiology*; D006801:Humans; D007473:Ion Channels / Q000378:metabolism; D010770:Phosphotransferases / Q000378:metabolism; D018160:Receptors, Cytoplasmic and Nuclear / Q000378:metabolism; D043562:Receptors, G-Protein-Coupled / Q000378:metabolism; D012984:Software
chemical_list: D007473:Ion Channels; D018160:Receptors, Cytoplasmic and Nuclear; D043562:Receptors, G-Protein-Coupled; D010770:Phosphotransferases