title: Benzimidazoles from Aryl Alkyl Ketones and 2-Amino Anilines by an Iodine Catalyzed Oxidative C(CO)-C(alkyl) Bond Cleavage.
abstract: Novel molecular iodine catalyzed cyclization reactions of 2-amino anilines with aryl alkyl ketones under oxidant and metal-free conditions are described. The reaction likely involves sequential C-N bond formation followed by C(CO)-C(alkyl) bond cleavage. Various 2-substituted benzimidazoles are obtained in moderate to good yields in a single step from readily available acetophenones, propiophenones, and phenylacetophenones.
authors.affiliation: Division of Natural Products Chemistry, CSIR-Indian Institute of Chemical Technology , Hyderabad 500607, India.
authors.forename: Owk
authors.initials: O
authors.lastname: Ravi
authors.affiliation: Division of Natural Products Chemistry, CSIR-Indian Institute of Chemical Technology , Hyderabad 500607, India.
authors.forename: Altab
authors.initials: A
authors.lastname: Shaikh
authors.affiliation: Division of Natural Products Chemistry, CSIR-Indian Institute of Chemical Technology , Hyderabad 500607, India.
authors.forename: Atul
authors.initials: A
authors.lastname: Upare
authors.affiliation: Centre for Nuclear Magnetic Resonance, CSIR-Indian Institute of Chemical Technology , Hyderabad 500 007, India.
authors.forename: Kiran Kumar
authors.initials: KK
authors.lastname: Singarapu
authors.affiliation: Division of Natural Products Chemistry, CSIR-Indian Institute of Chemical Technology , Hyderabad 500607, India.
authors.forename: Surendar Reddy
authors.identifier: 0000-0002-4830-2353
authors.initials: SR
authors.lastname: Bathula