title: Evaluation of myocardial deformation in patients with Kawasaki disease using speckle-tracking echocardiography during mid-term follow-up.
abstract: Speckle-tracking echocardiography is a recently developed technique for the evaluation of myocardial deformation or strain. Our objective was to examine strain through a mid-term follow-up of patients with Kawasaki disease.
  
  
  METHODS
  We explored left ventricular mechanics using speckle-tracking echocardiography in 35 patients with a history of Kawasaki disease at least 6 months after the acute phase. We also included 30 healthy children as controls. Strain data sets were acquired for the quantification of left ventricular global strain, segmental strain, and left ventricular ejection fraction.
  
  
  RESULTS
  The mean age of our patients was 25.6±15.4 months. At a median follow-up of 57.5 months (16.5-98.2), although both values were in the normal range, the mean left ventricular ejection proportion of patients (57.3%) was a little lower than that of controls (p⩽0.05). Patient strain values at the basal inferoseptal (20.0), basal anterolateral (19.5), apical septal (23.3), and apical inferior (24.0) segments were lower compared with controls. In all, seven patients had coronary aneurysms during follow-up. Kawasaki disease patients with pyuria had lower left ventricular strain at the mid anterior, mid anteroseptal, apical anterior, and apical inferior segments and global longitudinal strain compared with patients with no pyuria (p⩽0.05).
  
  
  CONCLUSIONS
  In children with a history of Kawasaki disease, impairment of left ventricular mechanics occurs especially within the left anterior descending artery territories.
authors.affiliation: Pediatric Cardiology,Dr. Siyami Ersek Chest, Heart and Vessel Surgery Teaching and Research Hospital,Siyami Ersek Hospital,Istanbul,Turkey.
authors.forename: Reyhan
authors.initials: R
authors.lastname: Dedeoglu
authors.affiliation: Pediatric Cardiology,Dr. Siyami Ersek Chest, Heart and Vessel Surgery Teaching and Research Hospital,Siyami Ersek Hospital,Istanbul,Turkey.
authors.forename: Kenan
authors.initials: K
authors.lastname: Barut
authors.affiliation: Pediatric Cardiology,Dr. Siyami Ersek Chest, Heart and Vessel Surgery Teaching and Research Hospital,Siyami Ersek Hospital,Istanbul,Turkey.
authors.forename: Funda
authors.initials: F
authors.lastname: Oztunc
authors.affiliation: Pediatric Cardiology,Dr. Siyami Ersek Chest, Heart and Vessel Surgery Teaching and Research Hospital,Siyami Ersek Hospital,Istanbul,Turkey.
authors.forename: Sezen
authors.initials: S
authors.lastname: Atik
authors.affiliation: Pediatric Cardiology,Dr. Siyami Ersek Chest, Heart and Vessel Surgery Teaching and Research Hospital,Siyami Ersek Hospital,Istanbul,Turkey.
authors.forename: Amra
authors.initials: A
authors.lastname: Adrovic
authors.affiliation: Pediatric Cardiology,Dr. Siyami Ersek Chest, Heart and Vessel Surgery Teaching and Research Hospital,Siyami Ersek Hospital,Istanbul,Turkey.
authors.forename: Sezgin
authors.initials: S
authors.lastname: Sahin
authors.affiliation: Pediatric Cardiology,Dr. Siyami Ersek Chest, Heart and Vessel Surgery Teaching and Research Hospital,Siyami Ersek Hospital,Istanbul,Turkey.
authors.forename: Dicle
authors.initials: D
authors.lastname: Cengiz
authors.affiliation: Pediatric Cardiology,Dr. Siyami Ersek Chest, Heart and Vessel Surgery Teaching and Research Hospital,Siyami Ersek Hospital,Istanbul,Turkey.
authors.forename: Ozgur
authors.initials: O
authors.lastname: Kasapcopur
mesh_terms: D016022:Case-Control Studies; D002675:Child, Preschool; D003323:Coronary Aneurysm / Q000000981:diagnostic imaging*; D004452:Echocardiography; D005260:Female; D005500:Follow-Up Studies; D006352:Heart Ventricles / Q000000981:diagnostic imaging; D006801:Humans; D007223:Infant; D008297:Male; D009080:Mucocutaneous Lymph Node Syndrome / Q000150:complications / Q000503:physiopathology*; D009206:Myocardium / Q000473:pathology*; D014421:Turkey; D018487:Ventricular Dysfunction, Left / Q000000981:diagnostic imaging*
keywords: Kawasaki disease; Myocardial deformation; myocarditis; speckle-tracking echocardiography; strain