title: Current protocols in the management of oral submucous fibrosis: An update.
abstract: Oral submucous fibrosis (OSMF) is a debilitating condition of oral cavity which has significant potential for malignant transformation. In spite of over 20 years of research, the pathogenesis of the condition is still obscure and no single management modality is effective. Many OSMF treatment protocols have been proposed to alleviate the signs and symptoms of the disorder and there is overwhelming evidence that as areca nut is primary cause, stopping its use may have a considerable effect on symptoms rather than reversing pre-existing fibrosis. We present a review of the current protocols for managing OSMF.
authors.affiliation: Department of Oral and Maxillofacial Surgery, Navodaya Dental College and Hospital, Raichur, Karnataka, India.
authors.forename: Gururaj
authors.initials: G
authors.lastname: Arakeri
authors.affiliation: Department of Oral and Maxillofacial Surgery, Bapuji Dental College and Hospital, Davangere, Karnataka, India.
authors.forename: Kirthi Kumar
authors.initials: KK
authors.lastname: Rai
authors.affiliation: Department of Oral and Maxillofacial Surgery and Oral Disease of Arnaldo Viera de Carvalho Cancer Institute, Sao Paulo, Brazil.
authors.forename: George
authors.initials: G
authors.lastname: Boraks
authors.affiliation: Department of Medical Oncology, HCG Cancer Hospital, Bangalore, India.
authors.forename: Shekar Gowda
authors.initials: SG
authors.lastname: Patil
authors.affiliation: King Fahad Medical City, Department of Dentistry, Faculty of Dentistry, King Saud University, Riyadh, Saudi Arabia.
authors.forename: Abdulsalam S
authors.initials: AS
authors.lastname: Aljabab
authors.affiliation: Department of Oral and Maxillofacial Surgery, Radboud University Medical Centre, Nijmegen, The Netherlands.
authors.forename: M A W
authors.initials: MAW
authors.lastname: Merkx
authors.affiliation: Center for Oral Health Research, Oral Medicine Department, Newcastle University, Newcastle upon Tyne, UK.
authors.forename: Marco
authors.initials: M
authors.lastname: Carrozzo
authors.affiliation: Department of Oral & Maxillofacial Surgery, Queen Alexandra Hospital, Cosham, Portsmouth, UK.
authors.forename: Peter A
authors.initials: PA
authors.lastname: Brennan
mesh_terms: D001114:Areca / Q000009:adverse effects; D000072700:Conservative Treatment; D006801:Humans; D009914:Oral Submucous Fibrosis / Q000473:pathology / Q000628:therapy*; D019647:Oral Surgical Procedures; D026741:Physical Therapy Modalities; D011230:Precancerous Conditions / Q000473:pathology / Q000628:therapy*; D015912:Thrombolytic Therapy
keywords: management; oral submucous fibrosis; review; treatment