title: Cardiovascular comorbidity in patients with chronic obstructive pulmonary disease in the Canary Islands (CCECAN study).
abstract: Numerous studies have shown a high prevalence of cardiovascular disease in patients with chronic obstructive pulmonary disease (COPD). The aim of this study was to analyse the prevalence of cardiovascular risk factors and comorbidity in a Canary Islands population diagnosed with COPD, and compared it with data from the general population.
  
  
  
  A cross-sectional study was carried out in 300 patients with COPD and 524 subjects without respiratory disease (control group). The two groups were compared using standard bivariate methods. Logistic regression models were used to estimate the cardiovascular risks in COPD patients compared to control group.
  
  
  
  Patients with COPD showed a high prevalence of hypertension (72%), dyslipidaemia (73%), obesity (41%), diabetes type 2 (39%), and sleep apnoea syndrome (30%) from mild stages of the disease (GOLD 2009). There was a 22% prevalence of cardiac arrhythmia, 16% of ischaemic heart disease, 16% heart failure, 12% peripheral vascular disease, and 8% cerebrovascular disease. Compared to the control group, patients with COPD had a higher risk of dyslipidaemia (OR 3.24, 95% CI; 2.21-4.75), diabetes type 2 (OR 1.52, 95% CI; 1.01-2,28), and ischaemic heart disease (OR 2.34, 95% CI; 1.22-4.49). In the case of dyslipidaemia, an increased risk was obtained when adjusted for age, gender, and consumption of tobacco (OR 5.04, 95% CI; 2.36-10.74).
  
  
  
  Patients with COPD resident in the Canary Islands have a high prevalence of hypertension, dyslipidaemia, ischaemic heart disease, and cardiac arrhythmia. Compared to general population, patients with COPD have a significant increase in the risk of dyslipidaemia.
authors.affiliation: Servicio de Neumología y Cirugía Torácica, Hospital Universitario Nuestra Señora de La Candelaria, Santa Cruz de Tenerife, España. Electronic address: juanmarcofigueira@gmail.com.
authors.forename: Juan Marco
authors.initials: JM
authors.lastname: Figueira Gonçalves
authors.affiliation: Servicio de Neumología y Cirugía Torácica, Hospital Universitario Nuestra Señora de La Candelaria, Santa Cruz de Tenerife, España.
authors.forename: Rafael
authors.initials: R
authors.lastname: Dorta Sánchez
authors.affiliation: Unidad de Investigación, Hospital Universitario Nuestra Señora de La Candelaria, Santa Cruz de Tenerife, España.
authors.forename: María Del Cristo
authors.initials: MDC
authors.lastname: Rodri Guez Pérez
authors.affiliation: Servicio de Neumología y Cirugía Torácica, Hospital Universitario Nuestra Señora de La Candelaria, Santa Cruz de Tenerife, España.
authors.forename: Pedro
authors.initials: P
authors.lastname: Viña Manrique
authors.affiliation: Servicio de Neumología y Cirugía Torácica, Hospital Universitario Nuestra Señora de La Candelaria, Santa Cruz de Tenerife, España.
authors.forename: David
authors.initials: D
authors.lastname: Díaz Pérez
authors.affiliation: Servicio de Neumología y Cirugía Torácica, Hospital Universitario Nuestra Señora de La Candelaria, Santa Cruz de Tenerife, España.
authors.forename: Cristina
authors.initials: C
authors.lastname: Guzmán Saenz
authors.affiliation: Servicio de Neumología y Cirugía Torácica, Hospital Universitario Nuestra Señora de La Candelaria, Santa Cruz de Tenerife, España.
authors.forename: Juan Manuel
authors.initials: JM
authors.lastname: Palmero Tejera
authors.affiliation: Servicio de Neumología y Cirugía Torácica, Hospital Universitario Nuestra Señora de La Candelaria, Santa Cruz de Tenerife, España.
authors.forename: Alicia
authors.initials: A
authors.lastname: Pérez Rodríguez
authors.affiliation: Servicio de Neumología y Cirugía Torácica, Hospital Universitario Nuestra Señora de La Candelaria, Santa Cruz de Tenerife, España.
authors.forename: Lorenzo
authors.initials: L
authors.lastname: Pérez Negrín
mesh_terms: D000368:Aged; D001145:Arrhythmias, Cardiac / Q000453:epidemiology; D002318:Cardiovascular Diseases / Q000453:epidemiology* / Q000503:physiopathology; D003430:Cross-Sectional Studies; D050171:Dyslipidemias / Q000453:epidemiology; D005260:Female; D006801:Humans; D006973:Hypertension / Q000453:epidemiology; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000453:epidemiology; D015995:Prevalence; D029424:Pulmonary Disease, Chronic Obstructive / Q000150:complications* / Q000453:epidemiology; D012307:Risk Factors; D013030:Spain / Q000453:epidemiology
keywords: Cardiovascular risk; Chronic obstructive pulmonary disease; Enfermedad pulmonar obstructiva crónica; Prevalence of cardiovascular morbidity; Prevalencia de comorbilidad cardiovascular; Riesgo cardiovascular