title: Coarse-Graining the Fluid Flow around a Human Sperm.
abstract: The flagellar beat is extracted from human sperm digital imaging microscopy and used to determine the flow around the cell and its trajectory, via boundary element simulation. Comparison of the predicted cell trajectory with observation demonstrates that simulation can predict fine-scale sperm dynamics at the qualitative level. The flow field is also observed to reduce to a time-dependent summation of regularized Stokes flow singularities, approximated at leading order by a blinking force triplet. Such regularized singularity decompositions may be used to upscale cell level detail into population models of human sperm motility.
authors.affiliation: The Hakubi Center for Advanced Research, Kyoto University, Kyoto 606-8501, Japan.|Research Institute for Mathematical Sciences, Kyoto University, Kyoto 606-8502, Japan.
authors.forename: Kenta
authors.initials: K
authors.lastname: Ishimoto
authors.affiliation: Department of Mathematics, University of York, York YO10 5DD, United Kingdom.|Institute for Metabolism and Systems Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham B15 2TT, United Kingdom.|Centre for Human Reproductive Science, Birmingham Women's NHS Foundation Trust, Birmingham B15 2TG, United Kingdom.
authors.forename: Hermes
authors.initials: H
authors.lastname: Gadêlha
authors.affiliation: Wolfson Centre for Mathematical Biology, Mathematical Institute, University of Oxford, Oxford OX2 6GG, United Kingdom.
authors.forename: Eamonn A
authors.initials: EA
authors.lastname: Gaffney
authors.affiliation: School of Mathematics, University of Birmingham, Birmingham B15 2TT, United Kingdom.|Institute for Metabolism and Systems Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham B15 2TT, United Kingdom.|Centre for Human Reproductive Science, Birmingham Women's NHS Foundation Trust, Birmingham B15 2TG, United Kingdom.
authors.forename: David J
authors.initials: DJ
authors.lastname: Smith
authors.affiliation: Institute for Metabolism and Systems Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham B15 2TT, United Kingdom.|Centre for Human Reproductive Science, Birmingham Women's NHS Foundation Trust, Birmingham B15 2TG, United Kingdom.
authors.forename: Jackson
authors.initials: J
authors.lastname: Kirkman-Brown
mesh_terms: D001696:Biomechanical Phenomena; D003198:Computer Simulation; D005407:Flagella; D006801:Humans; D057446:Hydrodynamics; D008297:Male; D008954:Models, Biological; D013081:Sperm Motility