title: [Intraocular ferritin production due to an iron-containing intraocular foreign body].
abstract: BACKGROUND
  Ocular siderosis is a rare but severe complication of open globe trauma with intraocular retention of a metallic foreign body.
  
  
  METHODS
  We report a case of recurrent uveitis in a 37-year-old patient. The ophthalmic examination revealed poor vision in the left eye, lid edema, limbal scleromalacia, hyphema and severe ocular hypertension. Orbital CT showed the presence of a radio-opaque IOFB between the crystalline lens and vitreous body. An aqueous humor sample was obtained for iron and ferritin levels. The results came back 100 and 2000 times higher, respectively, than the serum reference values.
  
  
  CONCLUSIONS
  The very high iron content is the result of a sustained release from the metallic INFB and is responsible for ocular siderosis in our patient. The extremely high ferritin level would be the result of in situ synthesis by the various cells of the ocular structures in order to preserve the components of the eye. Measurement of these two levels would improve the diagnosis, prognosis and treatment of metallic IOFBs.
authors.affiliation: Faculté de médecine et de pharmacie de Fès, université Sidi Mohamed Ben Abdellah, Fès, Maroc; Service de biochimie-toxicologie, hôpital militaire Moulay Ismail, boulevard Mohamed El Hansali, 50000 Meknès, Maroc. Electronic address: boukhrissi.fatima@gmail.com.
authors.forename: F
authors.initials: F
authors.lastname: El Boukhrissi
authors.affiliation: Service d'ophtalmologie, hôpital militaire Moulay Ismail, Meknès, Maroc; Faculté de médecine et de pharmacie de Rabat, université Mohamed V, Rabat, Maroc.
authors.forename: A
authors.initials: A
authors.lastname: Laktaoui
authors.affiliation: Faculté de médecine et de pharmacie de Fès, université Sidi Mohamed Ben Abdellah, Fès, Maroc; Service de Radiologie, hôpital militaire Moulay Ismail, Meknès, Maroc.
authors.forename: A
authors.initials: A
authors.lastname: Hommadi
authors.affiliation: Service de biochimie-toxicologie, hôpital militaire Moulay Ismail, boulevard Mohamed El Hansali, 50000 Meknès, Maroc; Faculté de médecine et de pharmacie de Rabat, université Mohamed V, Rabat, Maroc.
authors.forename: Y
authors.initials: Y
authors.lastname: Bamou
authors.affiliation: Service de biochimie-toxicologie, hôpital militaire Moulay Ismail, boulevard Mohamed El Hansali, 50000 Meknès, Maroc; Faculté de médecine et de pharmacie de Rabat, université Mohamed V, Rabat, Maroc.
authors.forename: L
authors.initials: L
authors.lastname: Balouch
mesh_terms: D000328:Adult; D005123:Eye / Q000378:metabolism* / Q000473:pathology; D005128:Eye Diseases / Q000175:diagnosis* / Q000209:etiology* / Q000378:metabolism; D005129:Eye Foreign Bodies / Q000150:complications* / Q000175:diagnosis; D015807:Eye Injuries, Penetrating / Q000150:complications / Q000175:diagnosis / Q000378:metabolism; D005293:Ferritins / Q000378:metabolism*; D006801:Humans; D007501:Iron; D008297:Male; D012806:Siderosis / Q000175:diagnosis* / Q000209:etiology / Q000378:metabolism
chemical_list: D005293:Ferritins; D007501:Iron
keywords: CEIO métallique; Fer; Ferritin; Ferritine; Iron; Metallic IOFB; Ocular siderosis; Sidérose oculaire