title: Leptomonas seymouri and Crithidia fasciculata exoantigens can discriminate human cases of visceral leishmaniasis from American tegumentary leishmaniasis ones.
abstract: Exoantigens (exo) from Leptomonas seymouri and Crithidia fasciculata were used in an enzyme linked immunosorbent assay (ELISA), showing 100% reactivity with sera from visceral leishmaniasis (VL) cases, and no reactivity with American tegumentary leishmaniasis (ATL) ones. Our results have indicated that these exoantigens can be applied in the discrimination of VL and ATL cases.
authors.affiliation: Universidade de São Paulo, Instituto de Medicina Tropical de São Paulo, São Paulo, Brazil.
authors.forename: Norival
authors.initials: N
authors.lastname: Kesper
authors.affiliation: Universidade de São Paulo, Instituto de Ciências Biomédicas, Departamento de Parasitologia, São Paulo, Brazil.
authors.forename: Marta Maria G
authors.initials: MM
authors.lastname: Teixeira
authors.affiliation: Universidade de São Paulo, Instituto de Medicina Tropical de São Paulo, São Paulo, Brazil.|Instituto Emilio Ribas de São Paulo, São Paulo, Brazil.
authors.forename: José Angelo L
authors.initials: JA
authors.lastname: Lindoso
authors.affiliation: Universidade Federal de São Paulo, Escola Paulista de Medicina, Departamento de Microbiologia, Imunologia e Parasitologia, São Paulo, Brazil.
authors.forename: Clara Lúcia
authors.initials: CL
authors.lastname: Barbieri
authors.affiliation: Universidade de São Paulo, Instituto de Medicina Tropical de São Paulo, São Paulo, Brazil.|Universidade de São Paulo, Faculdade de Medicina, Departamento de Medicina Preventiva, São Paulo, Brazil.
authors.forename: Eufrosina Setsu
authors.initials: ES
authors.lastname: Umezawa
mesh_terms: D000913:Antibodies, Protozoan / Q000097:blood; D000953:Antigens, Protozoan / Q000097:blood*; D016831:Crithidia fasciculata / Q000276:immunology*; D003429:Cross Reactions; D004797:Enzyme-Linked Immunosorbent Assay; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D007893:Leishmania donovani / Q000276:immunology*; D016773:Leishmaniasis, Cutaneous / Q000175:diagnosis* / Q000469:parasitology; D007898:Leishmaniasis, Visceral / Q000175:diagnosis* / Q000469:parasitology; D014351:Trypanosomatina / Q000276:immunology*
chemical_list: D000913:Antibodies, Protozoan; D000953:Antigens, Protozoan; D007074:Immunoglobulin G