title: Auditory and Visual Executive Functions in Children and Response to Methylphenidate: A Randomized Controlled Trial.
abstract: Objectives:The aim of the study was to assess auditory and visually based executive functions (EFs) and the effect of methylphenidate (MPH) in children with ADHD.Methods:Thirty-six boys between the ages of 8.3 and 9.7 years with ADHD and 36 matched controls were included. The study group was randomized into MPH and placebo for 7 days each in a crossover design. A Cued Choice Reaction Time (CCRT) test that included incongruent cuing was administered at baseline and following 1 and 2 weeks.Results:The difference between the study and control groups was more evident with visual cues and incongruent cuing. Increased gains by children with predominantly hyperactive-impulsive\combined (HI\C) type of ADHD were observed under MPH.Conclusions:The differences between children with ADHD and typical children are more pronounce under incongruent auditory cuing . The gains attributable to MPH are more specific to tasks involving auditory and visual EFs and in children with HI\C type ADHDs.
authors.affiliation: Haifa University, Israel.
authors.forename: Yaffa
authors.initials: Y
authors.lastname: Hadar
authors.affiliation: Technion-Israel Institute of Technology, Haifa, Israel.
authors.forename: Shraga
authors.initials: S
authors.lastname: Hocherman
authors.affiliation: Haifa University, Israel.
authors.forename: Oren
authors.initials: O
authors.lastname: Lamm
authors.affiliation: Technion-Israel Institute of Technology, Haifa, Israel.
authors.forename: Emanuel
authors.initials: E
authors.lastname: Tirosh
mesh_terms: D001289:Attention Deficit Disorder with Hyperactivity / Q000188:drug therapy; D000697:Central Nervous System Stimulants / Q000494:pharmacology / Q000627:therapeutic use; D002648:Child; D004311:Double-Blind Method; D056344:Executive Function; D006801:Humans; D008297:Male; D008774:Methylphenidate / Q000494:pharmacology / Q000627:therapeutic use; D011930:Reaction Time; D016896:Treatment Outcome
chemical_list: D000697:Central Nervous System Stimulants; D008774:Methylphenidate
keywords: ADHD; executive function; methylphenidate