title: Reproductive parameters of dairy goats after receiving two doses of d-cloprostenol at different intervals.
abstract: This study evaluated the efficiency of two d-cloprostenol injections at different intervals on the reproductive parameters of dairy goats. Trial 1 comprised 54 goats allocated to receive two 37.5μg d-cloprostenol doses at intervals of seven (T7, n=19), 10 (T10, n=18), and 11.5 (T11.5, n=17) days. Trial 2 comprised 62 goats allocated to receive injections at T7(n=30) and T11.5(n=32). Ultrasonography was done and blood was collected just before d-cloprostenol injections. After the second dose, goats were artificially inseminated (AI) with frozen-thawed semen at 18-24h (Trial 1) or at 10-24h (adjusted according to the time of estrus onset in Trial 2) after estrus detection. Estrus response rate did not differ (P>0.05) among groups in Trials 1 (T7=94.7%; T10=88.9%; T11.5=88.2%) and 2 (T7=90.0%; T11.5=96.9). All females showed progesterone concentrations >1ng/mL before both d-cloprostenol injections. The largest follicle diameter present on ovaries was similar (P>0.05) among treatments at the first and second dose. The second largest follicle diameter was superior (P<0.05) to T7than to T10and T11.5goats at first dose only. This possibly resulted in lower interval to estrus (P<0.05) in T7-treated goats than other treated goats in both trials. The conception rate was similar among treatment groups in Trials 1 (T7=55.6%; T10=18.8%; T11.5=26.7%) and 2 (T7=85.2%; T11.5=93.6%). The three treatments efficiently synchronized estrus. T7and T11.5protocols resulted in high estrus synchrony and conception rates when adjusting the AI time according to interval of estrus.
authors.affiliation: Faculty of Veterinary Medicine, Fluminense Federal University, Av. Vital Brasil Filho, 64, CEP 24230-340, Niterói, RJ, Brazil.
authors.forename: A L R S
authors.initials: ALRS
authors.lastname: Maia
authors.affiliation: Faculty of Veterinary Medicine, Fluminense Federal University, Av. Vital Brasil Filho, 64, CEP 24230-340, Niterói, RJ, Brazil.
authors.forename: F Z
authors.initials: FZ
authors.lastname: Brandão
authors.affiliation: Faculty of Veterinary Medicine, Fluminense Federal University, Av. Vital Brasil Filho, 64, CEP 24230-340, Niterói, RJ, Brazil; Faculty of Veterinary Medicine, School of Health Sciences, Universidade do Grande Rio, Rua Prof. José de Souza Herdy, 1160, CEP 25071-202, Duque de Caxias, RJ, Brazil.
authors.forename: J M G
authors.initials: JMG
authors.lastname: Souza-Fabjan
authors.affiliation: Faculty of Veterinary Medicine, Fluminense Federal University, Av. Vital Brasil Filho, 64, CEP 24230-340, Niterói, RJ, Brazil.
authors.forename: M F A
authors.initials: MFA
authors.lastname: Balaro
authors.affiliation: College of Agricultural and Veterinary Sciences, São Paulo State University, Access by Prof. Paulo Donato Castellane, s/n, CEP 14.884-900, Jaboticabal, SP, Brazil.
authors.forename: M E F
authors.initials: MEF
authors.lastname: Oliveira
authors.affiliation: Embrapa Goats and Sheep Research Center, Estrada Sobral/Groaíras, km 04, CP 145, CEP 62010-970, Sobral, CE, Brazil.
authors.forename: O
authors.initials: O
authors.lastname: Facó
authors.affiliation: Embrapa Goats and Sheep Research Center, Estrada Sobral/Groaíras, km 04, CP 145, CEP 62010-970, Sobral, CE, Brazil. Electronic address: jeferson.fonseca@embrapa.br.
authors.forename: J F
authors.initials: JF
authors.lastname: Fonseca
mesh_terms: D000818:Animals; D003008:Cloprostenol / Q000008:administration & dosage / Q000494:pharmacology*; D004334:Drug Administration Schedule; D030762:Estrous Cycle / Q000187:drug effects*; D004973:Estrus Synchronization / Q000379:methods; D005260:Female; D005298:Fertility / Q000187:drug effects*; D006041:Goats / Q000502:physiology*; D007315:Insemination, Artificial / Q000662:veterinary; D008186:Luteolytic Agents / Q000008:administration & dosage / Q000494:pharmacology*; D011247:Pregnancy
chemical_list: D008186:Luteolytic Agents; D003008:Cloprostenol
keywords: AI; Caprine; PGF2α analog; Prostaglandin; Reproductive performance