title: Collagenoma in a Patient With Down Syndrome: A Case Report and Review of the Literature.
abstract: A 26-year-old woman with Down syndrome presented with a 4-cm-sized palpable mass in the sacrococcygeal region. Histologic evaluation of the specimen revealed densely packed collagen fibers in the dermis, which is consistent with a collagenoma. Masson trichrome staining showed dense fibrosis, and elastic Van Gieson staining revealed a significant decrease in elastic tissue. The clinicopathologic characteristics of this patient and 4 previously reported cases are discussed in detail.
authors.affiliation: Departments of Radiology, and.
authors.forename: Sun Young
authors.initials: SY
authors.lastname: Choi
authors.forename: Sanghui
authors.initials: S
authors.lastname: Park
mesh_terms: D000328:Adult; D004314:Down Syndrome / Q000150:complications*; D005260:Female; D006801:Humans; D009506:Nevus / Q000150:complications* / Q000473:pathology*