title: Influenza-induced lung Trm: not all memories last forever.
abstract: In the light of new findings that lung tissue resident memory CD8+T cells (Trm) represent major mediators of heterosubtypic immunity against influenza virus, it is of utmost importance to understand the basic biological mechanisms behind induction, formation and maintenance of this cell population. Addressing these important knowledge gaps will potentially inform development of superior, broadly protective influenza vaccines and new immunization strategies.
authors.affiliation: Department of Microbiology, University of Iowa, Iowa City, IA, USA.
authors.forename: Natalija
authors.initials: N
authors.lastname: Van Braeckel-Budimir
authors.affiliation: Department of Microbiology, University of Iowa, Iowa City, IA, USA.|Department of Pathology, University of Iowa, Iowa City, IA, USA.|Interdisciplinary Graduate Program in Immunology, University of Iowa, Iowa City, IA, USA.
authors.forename: John T
authors.initials: JT
authors.lastname: Harty
mesh_terms: D000818:Animals; D018414:CD8-Positive T-Lymphocytes / Q000276:immunology*; D006801:Humans; D007156:Immunologic Memory; D007252:Influenza Vaccines / Q000276:immunology*; D007251:Influenza, Human / Q000276:immunology*; D008168:Lung / Q000276:immunology* / Q000821:virology; D032541:Mass Vaccination; D009975:Orthomyxoviridae / Q000276:immunology*; D009976:Orthomyxoviridae Infections / Q000276:immunology*
chemical_list: D007252:Influenza Vaccines