title: Two novel MYLK nonsense mutations causing thoracic aortic aneurysms/dissections in patients without apparent family history.
authors.affiliation: Center of Medical Genetics, Faculty of Medicine and Health Sciences, University of Antwerp and Antwerp University Hospital, Antwerp, Belgium.
authors.forename: I
authors.identifier: 0000-0002-9668-0535
authors.initials: I
authors.lastname: Luyckx
authors.affiliation: Center of Medical Genetics, Faculty of Medicine and Health Sciences, University of Antwerp and Antwerp University Hospital, Antwerp, Belgium.
authors.forename: D
authors.initials: D
authors.lastname: Proost
authors.affiliation: Department of Thoracic and Vascular Surgery, Faculty of Medicine and Health Sciences, University of Antwerp and Antwerp University Hospital, Antwerp, Belgium.
authors.forename: J M H
authors.initials: JMH
authors.lastname: Hendriks
authors.affiliation: Department of Cardiology, Faculty of Medicine and Health Sciences, University of Antwerp and Antwerp University Hospital, Antwerp, Belgium.
authors.forename: J
authors.initials: J
authors.lastname: Saenen
authors.affiliation: Department of Cardiology, Faculty of Medicine and Health Sciences, University of Antwerp and Antwerp University Hospital, Antwerp, Belgium.
authors.forename: E M
authors.initials: EM
authors.lastname: Van Craenenbroeck
authors.affiliation: Department of Cardiology, Faculty of Medicine and Health Sciences, University of Antwerp and Antwerp University Hospital, Antwerp, Belgium.
authors.forename: T
authors.initials: T
authors.lastname: Vermeulen
authors.affiliation: Center of Medical Genetics, Faculty of Medicine and Health Sciences, University of Antwerp and Antwerp University Hospital, Antwerp, Belgium.
authors.forename: N
authors.initials: N
authors.lastname: Peeters
authors.affiliation: Center of Medical Genetics, Faculty of Medicine and Health Sciences, University of Antwerp and Antwerp University Hospital, Antwerp, Belgium.
authors.forename: W
authors.initials: W
authors.lastname: Wuyts
authors.affiliation: Department of Cardiac surgery, Faculty of Medicine and Health Sciences, University of Antwerp and Antwerp University Hospital, Antwerp, Belgium.
authors.forename: I
authors.initials: I
authors.lastname: Rodrigus
authors.affiliation: Center of Medical Genetics, Faculty of Medicine and Health Sciences, University of Antwerp and Antwerp University Hospital, Antwerp, Belgium.
authors.forename: A
authors.initials: A
authors.lastname: Verstraeten
authors.affiliation: Center of Medical Genetics, Faculty of Medicine and Health Sciences, University of Antwerp and Antwerp University Hospital, Antwerp, Belgium.
authors.forename: L
authors.initials: L
authors.lastname: Van Laer
authors.affiliation: Center of Medical Genetics, Faculty of Medicine and Health Sciences, University of Antwerp and Antwerp University Hospital, Antwerp, Belgium.|Department of Human Genetics, Radboud University Nijmegen Medical Center, Nijmegen, Netherlands.
authors.forename: B L
authors.initials: BL
authors.lastname: Loeys
mesh_terms: D000368:Aged; D000784:Aortic Dissection / Q000235:genetics* / Q000503:physiopathology; D017545:Aortic Aneurysm, Thoracic / Q000235:genetics* / Q000503:physiopathology; D002135:Calcium-Binding Proteins / Q000235:genetics*; D018389:Codon, Nonsense / Q000235:genetics; D005260:Female; D057895:Haploinsufficiency / Q000235:genetics; D006801:Humans; D008297:Male; D008487:Medical History Taking; D008875:Middle Aged; D009219:Myosin-Light-Chain Kinase / Q000235:genetics*; D010375:Pedigree
chemical_list: D002135:Calcium-Binding Proteins; D018389:Codon, Nonsense; C499378:MYLK protein, human; D009219:Myosin-Light-Chain Kinase