title: GSM4307319: HepG2-NTCP-HBx/tet with Dox for 4 days then without Dox for 4 days; Homo sapiens; OTHER
library_construction_protocol: The HepDE19 cell genomic DNA was extracted using a Qiagen genomic DNA extraction kit. The 4C-seq and Hi-C sample were extracted following 4C and Hi-C methods. RNA was harvested using Trizol reagent. For whole genome DNA sequencing and RNA-seq, libraries were prepared according to Illumina's instructions accompanying the Kits. The Hi-C libraries were constructed following the published in situ Hi-C methods (PMID: 25497547). HBV-4C libraries were constructed mainly following the published 4C-seq methods (PMID: 22929766) except necessary adjustment.