title: 16S rRNA amplicon analysis of  ocean acidification minicosm experiment on marine microbes
design: 1.1.12 0.1um, 1.1.18 0.1um,  1.2.12 0.1um, 1.2.12 0.1um, 1.2.18 0.1um, 1.3.12 0.1um, 1.3.18 0.1um, 1.4.12  0.1um, 1.4.18 0.1um, 1.5.12 0.1um, 1.5.18 0.1um, 1.6.12 0.1um, 1.6.18 0.1um,  1.R.0 0.1um