title: sample XQC sequencing by Illumina GA II
design: More  effective biomarkers for use in tuberculosis prevention, diagnosis, and treatment, including markers that can discriminate between healthy individuals and those with latent infection, are urgently needed. To identify a set of such markers, we used Solexa sequencing to examine microRNA expression in the serum of patients with active disease(XQD), and healthy individuals with latent TB(XQA), and those with or without prior BCG inoculation(XQB and XQC).