title: MBD-seq of canine DLBCL
design: Methylated DNA was enriched by the MethylMiner Methylated DNA Enrichment Kit (Life Technologies) according to manufacturer s instructions. The methylated fraction of genomic DNA (100 ng) thus obtained was then employed to construct barcoded DNA libraries by using the TruSeq Nano DNA LT Library Prep Kit (Illumina) and sequenced with HiSeq2500 instrument (Illumina Inc.) following a 50 SE approach.