title: Understanding the genetic architecture of schizophrenia in Chinese population
design: Sequencing libraries were generated using Truseq Nano DNA HT Sample preparation Kit (Illumina USA) following manufacturers recommendations and index codes were added to attribute sequences to each sample. The genomic DNA is randomly fragmented to a size of 350bp by Covaris cracker, then DNA fragments were end polished, A-tailed, and ligated with the full-length adapter for Illumina sequencing with further PCR amplification. At last, PCR products were purified (AMPure XP system) and libraries were analyzed for size distribution by Agilent2100 Bioanalyzer and quantified using real-time PCR