title: Collagen induced arthritis rats before any treatment
design: Specific Pathogen Free (SPF) female Wistar were housed 5/cage, maintained in an environmentally controlled room with 12 hour light/dark cycle and kept on a standard chow and water ad libitum. Some rats were collagen induced to have rheumatoid arthritis disease.A group of rats was used before any treatments (RA_0), as baseline reference point to compare the final effect of the therapy at 34 days.