title: Sample: p1988_d0
design: The dataset contains T-cell Receptor Beta Chain sequences from patient p1988_and_p3488 at d0_and_d0. Individual cDNA molecules were labeled with an unique molecular identifier (UMI) tag prior to library  preparation. Custom adapters were introduced via PCR. Both sides of the amplicons have sample-specific barcode. Libraries were prepared generally according to our standardized protocol (http://www.frontiersin.org/Journal/10.3389/fimmu.2013.00456/abstract) with some modifications (see the main publication). Pair-end 2x100 sequencing was performed using Illumina HiSeq2500 with custom sequencing primers. Sequences for the sample p1988_d0 could be extracted from the file using the substring 'NNNNNNTAACGGTNNNNNNTCT'  for read 1 (contains sample-specific barcode AACGG and UMI dispalyed as 12xN). Sequences for the sample p3488_d0 could be extracted from the file using the substring 'NNNNNTNCGTATNTNNNNNNTCT'  for read 1 (contains sample-specific barcode CGTAT and UMI dispalyed as 12xN)