title:  30 x whole genome DNA sequence for NHLBI TOPMed sample NWD805165 
design:  Sequencing libraries are prepared with 500 ng input DNA using the KAPA Hyper Library Preparation Kit (PCR-free).  Covaris shearing targets 350 bp fragments.  Libraries are multiplexed in pools of 20 and each pool is sequenced on 2 1/2 flow cells of HiSeq X. 