title: High throughput sequencing of phage display library to profile active site specificity of protease ADAMTS13
design: This project involves high throughput sequencing of phage display libraries to profile active site specificity of proteases ADAMTS13 and Thrombin. Sequencing library was constructed as previously described: Kretz, C.A., et al., Massively parallel enzyme kinetics reveals the substrate recognition landscape of the metalloprotease ADAMTS13. Proc Natl Acad Sci U S A, 2015. 112(30): p. 9328-33