Exome of human male: Sample LGB_1_1
Solution hybridization exome capture was performed using the Illumina TruSeq system (Illumina Inc., San Diego, CA). Flow cell preparation and paired-end read sequencing were performed using the HiSeq 2000 sequencer (Vilboux et al. 2016) (Illumina Inc., San Diego, CA). Image analyses and base calling were performed as described (Vilboux et al. 2016). Reads were aligned to hg19, NCBI 37, using novoalign (Novocraft Technologies). Samples were sequenced to sufficient coverage such that at least 85% of the targeted exome was called with high quality variant detection (reported as genotype at every callable position).