title: ERCC6 mut fibroblast
design: DNA was randomly fragmented using a Covaris ultrasonic processor. Fragmented DNA was ligated with DNA adaptors (Illumina) and amplified using Illumina paired-end PCR primers. DNA libraries were quantified using a Qubit 2.0 Fluorometer (Life Technologies) and analysed using an Agilent Bioanalyzer 2100 to determine the insert sizes of the fragments in the libraries. The library of fragments was sequenced on an Illumina HiSeq X Ten platform.