title: acid whey fermemtation metagenome
design: Further genomic DNA quality evaluation regarding integrity/fragmentation was evaluated by Diversigen Inc. (Huston, TX, USA), where the samples were sent for sequencing. After the required quality of samples was assessed, the genomic DNA was prepared into libraries for sequencing by Nextera DNA Flex Library Preparation Kit (Illumina, Catalog No. 20018705) using Nextera Index Kit (Illumina, Catalog No. FC-121-1012). Quality appraisal of the library quantification and size estimation was determined using the fragment analyzer electrophoresis system (Advanced Analytical Technologies, Inc.). Then, sequencing was performed on an Illumina MiSeq (2  250bp).