library_construction_protocol: RNA was isolated from the cells using RNAeasy mini kit (Qiagen) according to manufacturer's protocol. Tumor tissues were cut into 1-2mm pieces and sonicated with lysis buffer using RNeasy mini kit (Qiagen) and RNA was isolated according to the manufacturer's protocol. RNA libraries were prepared for sequencing using standard Illumina protocols at the St. Jude Hartwell Center.