library_construction_protocol: Total human brain RNA was derived from post mortem cortex and provided by Agilent (Agilent Technologies, cat: 540143). For the preparation of mouse brain RNA, a male mouse (strain 129S2/SV) was sacrificed, and the entire brain was harvested and grained in Trizol (Thermo Fisher Scientific). Total RNA was obtained according to the manufacture's protocol. After rRNA depletetion, sequencing was performed using DNA nanoball sequencing technology, BGISEQ-500