library_construction_protocol: DNA was extracted from chromatin-DNA complexes released to supernatant by Mnase activity in HeLa S3 cells Libraries were prepared using NEBNext Ultra II DNA Library Prep kit (NEB #E7103), according to protocol of Nan Liu, published on protocols.io dx.doi.org/10.17504/protocols.io.bagaibse. The libraries were paired-end sequenced on Illumina NovaSeq 6000.