title: FUS-R521C-#212
design: We performed RNA-seq analyses on paired-end Illumina libraries from the spinal cords of 3 P38 disease end-stage FUS-R521C mice and 3 age-matched con- trols. A total of 37.33  3.77  106 reads per sample were obtained, and more than 98% of the reads were uniquely mapped to the mouse genome. We first analyzed the RNA-seq data using DESeq, which interrogated high throughput sequencing data for differ- ential expression