library_construction_protocol: Adherent cells were trypsinized using TrypLE for 8 minutes at 37oC. Generation and Barcoding of Gel Bead-In-Emulsions (GEMS) were performed according to standard 10X Genomics Reagent kit Protocol (Chromium Single Cell 3' Reagent kits). RNA libraries were prepared for sequencing using standard 10X Genomics Protocol (Chromium Single Cell 3' Reagent kits) D2 and D9 for H1 cells were processed in one batch; D22 and D32 H1 cells were processed in one batch; H9D9, H9D32, HS980D9 and HS980D32 were processed in one batch