library_construction_protocol: The total RNA were extracted using the RNeasy Mini Kit (Qiagen, 74104) following the manufacturer's protocol. RNA samples were quality-checked via the Agilent 2100 Bioanalyzer platform (Agilent Technologies). TruSeq Stranded mRNA library preparation and sequencing on Illumina HiSeq4000 were performed by Integragen, SA (Evry, France), according to the manufacturer's protocol.