library_construction_protocol: Total RNA was isolated from EndoC-βH1 samples using the RNeasy Plus Micro kit (Qiagen) and quantified using a Nanodrop (NanoDrop ND-1000; Thermo Fisher Scientific). A minimum of 500ng of high-quality RNA with RNA integrity number > 9 (as determined by Agilent Bioanalyzer) per sample and replicate was used for library preparation. RNA-seq was performed on a NovaSeq 6000 (Eurofins).