library_construction_protocol: For ATAC-sequencing sample preparation the Omni-ATAC Supplementary Protocol 1 was followed step by step as instructed by the authors (Corces et al., 2017). Nanodrop and Qubit methodologies were used to assess the concentration of the final amplified libraries. Library was constructed using the Omni-ATAC-Seq protocol (Corces et al., 2017). Library quality control and Illumina sequencing was performed at the YCGA following their standard protocols (https://medicine.yale.edu/keck/ycga/)