library_construction_protocol: In the A samples all four oligos were mixed before library preparation and sequencing. In the B and C samples two libraries were prepared, one with the B and one with the C samples and the sequenced together The quality and quantity of the RNA samples was checked using an Agilent bio-analyzer. RNA-SEQ libraries were generated using Illumina TruSEQ TotalRNA kits using the Illumina provided protocol. RNA-Seq; sequenced on an Illumina HiSEQ4000 using Illumina provided reagents and protocols