Potential role of inflammation promoting biliary microbiome in primary sclerosing cholangitis and cholangiocarcinoma
Bile samples were collected during endoscopic or surgical procedures and were collected twice if possible. Stool samples were collected on site at Mayo Clinic or at the patients home and mailed back to Mayo Clinic. For controls, patients with cholelithiasis and/or choledocholithiasis undergoing ERCP or surgery were consented. Both bile and stool 16S rDNA amplicons were sequenced on one lane of a MiSeq