title: Input data of untreated hela-s3 in early S phase, replicate 1
design: HeLa cells were collected at 2 or 4 hours after releasing to the S                 phase while EdU was added 15 minutes before harvesting. Genomic DNA were fragmented                 by sonication and biotin-labeled by click reaction, then end-repaired and ligated to                 the adaptor with NEBNext Ultra II DNA library preparation kit according to the                 manufacturer's instructions. One percent of each sample was amplified for input                 sequencing. Resulting libraries were sequenced by the Illumina NovaSeq                 system.