title: joint analysis of metabolome and transcriptome in system Xc- regulating glucose deprivation-induced cell death
design: Total RNA was extracted using mirVana RNA Isolation Kit (Ambion) following manufacturer's instructions. The qualified data were subjected to the subsequent analysis. Differential transcripts upon specific treatments were defined by P-value0.05 and foldchange2. Gene ontology (GO) analysis and KEGG enrichment were done by Hypergeometric Distribution Test as previously described.