title: Acquired Resistance Mechanisms to Osimertinib in EGFR Mutant Lung Cancer: Sample Sample_NCI0395_T1D_E_HGGKTBGX2
design: WXS-DNA was extracted using Qiagen AllPrep DNA/RNA mini kits. DNA libraries were prepared using Agilent exome capture kits (clinic v1, Agilent) and sequenced on Illumina HiSeq2000, 2500, and NextSeq500 according to the manufactures protocol (Illumina, San Diego, CA). Sequencer-generated bcl files were converted to fastq files using the bcl2fastq tool in CASAVA (Illumina, San Diego, CA) suite.