title: WGS of Genome in a Bottle HG003 Ion Torrent Proton within the NGS2 Study
design: For Ion Torrent libraries, each laboratory used the Ion Xpress                 Fragment Library kit per the manufacturers protocol, using 100ng of input DNA. For                 Ion Ampliseq exome sequencing, DNA was amplified through a massively multiplexed PCR                 reaction to create the library following the Ion Ampliseq Exome protocol. The                 libraries were then sequenced on either the Ion S5 or Ion Proton instruments using                 standard 200bp chemistries and protocols.