title: Hi-C sequencing data of HCT116 cells right after heat shock, replicate 2
design: First crosslink chromatin material using formaldehyde. Then digest the chromatin with a restriction enzyme cocktail. The 5'-overhangs are biotinylated, and the spatially close digested ends of DNA are ligated, purified, fragmented and enriched for the biotinylated fragments before being subject to custom library prep.