title: Exome sequencing of human blood sample
design: WXS library was prepared from the sample using Agilent-SureSelectXT Human All Exon V5. Biotinylated oligonucleotide capture probes were used to enrich the whole exome by hybridization. The workflow involved shearing of DNA, repairing ends, adenylation of 3' ends, followed by adapter ligation to generate paired-end libraries. The resulting libraries were purified, quantified, and hybridized with exome-specific biotinylated capture library. The resulting enriched DNA libraries were multiplexed by adding index tags by amplification, followed by purification.