HI-C data from Male no.2 from Anolis carolinensis
The Hi-C method allows the examination of genome-wide interactions (Dekker, Rippe et al. 2002). Hi-C introduces biotinylated nucleotides at ligation junctions after a restriction enzyme digestion using DpnII (that cuts at GATC) to then specifically purify these junctions (Lajoie, Dekker et al. 2015). Sequencing was performed in an Illumina NovaSeq 6000 machine in Novogene, California.