title: Whole exome sequencing of 146 tumor/normal pairs and RNA sequencing of the 146 tumors from 140 Hispanic/Latina women in California.
design: The KAPA HyperPlus Kit (part number KK8514) was used to generate libraries from 300ng DNA according to the KAPA-provided protocol. Libraries were pooled and sequence capture was performed with NimbleGen's SeqCap EZ exome v3, according to the manufacturer's protocol. The resulting post-capture enriched multiplexed sequencing libraries were used in cluster formation on an Illumina cBOT and paired-end sequencing was performed using Illumina-provided protocols for 2 × 100 bp paired-end sequencing.