title: Mouse lung cancer cell line
design: The qualified genomic DNA sample was randomly fragmented by Covaris technology and the size of the library fragments was mainly distributed between 150bp and 250bp. The end repair of DNA fragments was performed and an "A" base was added at the 3'- end of each strand.Adapters were then ligated to both ends of the end repaired/dA tailed DNA fragments for amplification and sequencing. Size-selected DNA fragments were amplified by ligation-mediated PCR (LM- PCR ), purified, and hybridized to the exome array for enrichment. Non-hybridized fragments were then washed out.