title: COPD.0007.BALC.L
design: RNA-Seq was performed on bronchial epithelial cells obtained by airway brushing, as described68-70, using the Hi-seq/Illumina platform at the NYU Langone Genomic Technology Cente. KEGG annotation was summarized at levels 1 to 3. Genes with an FDR-corrected adjusted p-value <0.25 were considered significantly differentiated, unless otherwise specified. Pathway analysis using differentially regulated genes (FDR<0.25) was done using Ingenuity Pathway Analysis (QIAGEN Inc.)71. Gene Set Enrichment Analysis (GSEA) was performed with differential genes (FDR<0.25) for dataset comparison, R package fgsea v1.4.172.