title: GSM6424225: RNA CNS (donor), CD45.1+CD88+CD317+ myeloid cells, Day15; Mus musculus; RNA-Seq
library_construction_protocol: Bone marrow chimeric mice (BL/6) were generated by injecting CD45.1+ bone marrow cells into irradiated CD45.2+ mice. These subsequently underwent induction with active experimental autoimmune encephalopathy (EAE). At peak of disease (day 15 post induction), cell suspensions from brain and spinal cord were sorted for CD88, CD317, and either CD45.1 or CD45.2 expression. Cell populations were subjected to single cell analysis using the 10X Multiomics platform. Library was prepared according to the manufacturer's instructions for the 10X Single Cell Multiome ATAC + Gene Expression kit