title: WXS of Homo sapiens: adulr female uterus
design: High-quality DNA isolate from the biological sample. This may include extraction and purification steps to ensure the integrity and concentration of the nucleic acids. The DNA  is fragmented into smaller pieces, ranging from 200 to 600 base pairs. The fragmented DNA ends are repaired to create blunt ends. In the case of sequencing platforms that require overhangs, an additional adenine (A) nucleotide is added to the 3' ends of the DNA fragments to facilitate adapter ligation. Specific adapters are ligated to the ends of the DNA fragments. These adapters contain sequences necessary for binding to the sequencing flow cell and may include unique molecular identifiersor barcodes for sample multiplexing.