sequences of bacteria
This dataset comprises raw 16S rRNA gene sequencing data derived from esophageal tissue samples of rats in a reflux esophagitis (RE) model. The study aimed to investigate the alterations in esophageal microbiota composition in response to RE and to evaluate the modulatory effects of Shunwei Jiangni Decoction (SWJN), a modified traditional Chinese medicine formula. Male Wistar rats were divided into four groups: normal control (Control), RE model (Mod), SWJN low-dose (SWJN_L), and SWJN high-dose (SWJN_H). Esophageal samples were collected after 4 weeks of treatment. The V3-V4 hypervariable region of the 16S rRNA gene was amplified and sequenced on the Illumina NovaSeq 6010 platform.