Repli-MiC-K562_WT_RepliMiC_Bio1
Libraries were constructed by the Repli-MiC strategy. Briefly,wild-type K562 cells were treated with BrdU for 15 min and fixed with 1% formaldehyde, digested by MNase,END-blunting, dA-tailing, and ligated with biotinylated linkers. Fragmentated DNA was enriched by anti-BrdU and then biotin. After that, DNA was tagged with adapters and sequenced. Biological replicate two.