title: Somatic mutations in 3,929 HPV-positive exfoliated cervical cell samples
design: Targeted panel sequencing (gene list below) with a custom-designed AmpliSeq panel using the Ion AmpliSeq Designer was conducted on paired tumor and germline DNA on the Ion Torrent S5 Sequencer, with an average coverage of 1,158x. We sequenced the entire exonic regions for these genes and deep sequence coverage was generated at each locus of interest for each sample. ARID1A,ATM,ATR,BCCIP,BRCA1,BRCA2,CDKN2A,EGFR,ERCC4,HMG20B,HNRNPC,IFNG,LYST,MAP3K4,MCM10,MET,MGA,MORF4L1,MORF4L2,PALB2,PRMB1,PIK3CA,PTEN,RAD51,RAD51B,RAD51C,RB1,SETD2,SHFM1,SMARCB1,TBXT,TERT,TP53,TSC1,TSC2,USP9X,VHL,XRCC2
library_name: PAP111484
identifiers.namespace: NCI-phs003691
identifiers.id: PAP111484