title: RNA-seq of SA
design: S. aureus Newman was grown to logarithmic phase in fresh TSB medium, then 500 M DL-mevalonolactone were added into the dosing group. After 4 h at 37 C, bacteria were collected and total RNAs were extracted using a Bacterial RNA Kit (Omega Bio-Tek). The transcriptomic sequencing and data analysis were performed by Shanghai Sangon Biotech.