title: Whole genome sequencing  MTB
design: A pairedend Illumina library was prepared by endrepairing the sheared fragments, adding an A overhang, and ligating Illumina adapters. The library was then sizeselected and PCRamplified according to the manufacturers instructions. Sequencing was carried out on an Illumina GAIIx instrument to generate pairedend reads of approximately 100 bp each.