design: Genomic DNA was extracted with Monarch HMW DNA Extraction Kit for Cells & Blood (New England Biolabs, # T3050L). We prepared Oxford Nanopore Technologies (ONT) libraries using the Ligation Sequencing Kit V14 (ONT, #SQK-LSK114), starting with 1 g of gDNA and following manufacturers instructions. Each library was loaded on a PromethION flow cell (ONT, FLO-PRO114M) and sequenced for 72h. Reads were basecalled using Dorado (0.3.0, Oxford Nanopore Technologies)