design: XR-seq (Excision Repair Sequencing): This technology is used to map DNA repair events genome-wide at single-nucleotide resolution. It involves isolating excision repair products (short DNA oligonucleotides) from cells after they have been exposed to DNA-damaging agents such as UV light. These excised DNA fragments are then ligated to sequencing adapters and subjected to next-generation sequencing. The sequencing reads are mapped back to the genome, allowing the identification of repair events and the determination of the exact location and frequency of these events. XR-seq provides a detailed and high-resolution view of DNA repair activity across the entire genome.