library_construction_protocol: Whole mouse lungs were used for isolation of RNA. Lungs were flash frozen 14 days after the completion of tamoxifen treatment, and suspended in RNA STAT-60 (Amsbio, Abingdon, UK) and then bullet blended with RNase free 0.9-2.0mm stainless steel beads SSB14B-RNA (Next Advance, Troy, NY) until homogenized. Additional RNA STAT-60 followed by chloroform were added prior to centrifugation. RNA was precipitated from the resulting colorless upper aqueous phase. RNA pellets were washed with 75% ethanol and resuspended in nuclease free water. The Ambion (Austin, TX) AM1907 Turbo DNA-free kit was used to remove any remaining DNA. RNA libraries for RNA sequencing were prepared with the Illumina TruSeq Stranded mRNA (polyA enrichment) Library.