design: Multiplex library preparation was performed using the KAPA Hyper Prep Kit (Roche, Santa Clara, CA) according to the manufacturers specifications. Hybrid capture of pooled libraries was performed using a custom oligonucleotide library (Integrated DNA Technologies).  Captured libraries were sequenced as paired-end 150 bp reads on an Illumina NovaSeq 6000 instrument (Illumina, San Diego, CA).