library_construction_protocol: Total RNA extraction was performed by Novogene following the manufacturer's protocol; RNA quality was assessed by Qubit/NanoDrop and Agilent 2100 Bioanalyzer (RIN ≥ 7.0). Poly(A)+ mRNA was purified from total RNA using oligo(dT) magnetic beads. Purified mRNA was fragmented, and first-strand cDNA was synthesized with random hexamers followed by second-strand synthesis incorporating dUTP (strand-specific protocol). After end repair, A-tailing, adaptor ligation, size selection, PCR amplification and purification, libraries were QC-checked by Qubit/real-time PCR and Agilent 2100 Bioanalyzer. Libraries were sequenced on an Illumina NovaSeq X Plus platform (paired-end 150 bp).