library_construction_protocol: RNA was harvested by quick RNA miniprep kit (Zymo research), and treated with DNaseI for following analysis. Stranded mRNA-seq libraries were prepared from total RNA (100 ng) using the KAPA Stranded mRNA-Seq kit (Roche) according to the manufacturer's standard protocol. Libraries were pooled and multiplex sequenced on an Illumina NovaSeq 6000 System (150-bp, paired-end, >30 × 106 reads per sample).