library_construction_protocol: Cells were crosslinked in 1% formaldehyde for 10 min at room temperature before reaction was stopped with glycine (125mM) for 5min. ChIP were carried out using the ChIP-IT High Sensitivity Kit (Actif Motif, 53040). Library were prepared by GenomEast platform of the IGBMC Strasbourg, a member of the 'France Génomique' consortium (ANR-10-INBS-0009).