library_construction_protocol: RNA extraction was performed using the RNeasy® Mini kit columns (Qiagen) following the manufacturer's instructions. RNA was quantified by Qubit RNA kit (Thermofischer Scientific) and qualified with the HS RNA kit for the Fragment Analyzer (Agilent Technologies). The mRNAseq librairies were prepared with the Illumina Stranded mRNA Prep Ligation kit using an input of 500ng of highquality RNA (RQN =10) following manufacturer's instructions. The librairies were profiled with the HS NGS kit for the Fragment Analyzer and quantified by qPCR using the KAPA library quantification kit (Roche Diagnostics), pooled and sequenced on the Illumina NextSeq550 High Output flow cell 150 cycles.