library_construction_protocol: Total RNA was extracted using the Monarch Total RNA Miniprep Kit (NEB, cat T2010). RNA-seq libraries were prepared using the QuantSeq 3' mRNA-Seq V2 Library Prep Kit FWD with UDI (Lexogen). The libraries were quantified with the Qubit dsDNA HS Assay (Fisher Scientific) and their length was assessed using a Fragment Analyzer with the HS NGS Fragment Kit (Agilent).