library_construction_protocol: Total RNA was isolated with the RNeasy kit (Qiagen, Hilden, Germany) according to the manufacturers protocol and including the optional DNase digestion step. Depletion of rRNA was performed with the mRNA Ribo-Zero magnetic kit (Epicentre, Madison, WI, USA) according to the manufacturer's instructions. The library was prepared from ribosomally depleted total RNA using the Scriptseq v2 RNA-seq (RNA sequencing) library preparation kit (Epicentre, Madison, WI, USA) according to the manufacturer's protocol.