design: Empty_vector_RNAseq_Dbt_MYCN_Clone2 cells, derived from the Dbt_MYCN parental population, were transfected with the empty vector EV (Origene). After RNA extraction (RNAeasy, Qiagen), libraries were prepared (Illumina TruSeq Stranded) and cDNA was synthesized using random primers.  Sequencing was performed on the Illumina HiSeq4000 with paired-end reads.