design: To construct a library for proximity mapping using Omni-C, we excysted sporozoites in vitro and purified them using 5 m PluriStrainer filters (Pluriselect, El Cajon, CA).  The Hi-C library was prepared using the manufacturers instructions of their Dovetail Omni-C kit, version 2.0 (CantataBio, Scotts Valley, CA).