library_construction_protocol: Total RNA was isolated for whole colonies, blood cells, vasculature, and Integrin alpha-6-, BSA-, or ALDH-positive cells -sorted by FACS with the Monarch® Total RNA Miniprep Kit (NEB) or NucleoSpin RNA, Mini kit for RNA purification (MACHEREY-NAGEL) following the manufacturer's protocols. RNA samples were sequenced (poly-A library prep, 150 bp insert size, paired-end, 20 million reads per sample) at the UC Davis Genome Center or the Novogene company.