library_construction_protocol: After 6 hours of exposure, media was removed, and cells were lysed in 0.3 mL Trizol, followed by RNA extraction. Samples were analyzed by BioSpyder using a custom-attenuated version of the Human Whole Transcriptome v2.1 assay. Pooled sequencing libraries were then distributed across multiple lanes of a HiSeq dual flow cell and analyzed on a NovaSeqX Ultra-High-Throughput Sequencing System (Illumina, San Diego, CA).