design: Genomic DNA extracted from skin lesion swabs of Acipenser baerii infected with Aeromonas salmonicida AB001. Genomic DNA was extracted using a Genomic DNA Extraction Kit (TransGen, China). DNA libraries were prepared using SQK-LSK109 kit and sequenced on PromethION 48 (Oxford Nanopore Technologies). Raw reads were basecalled with Guppy Basecaller v6.2.7, adapters and barcodes removed with Porechop v0.2.4, and de novo assembled with Flye v2.9.3. Genome annotation was performed using RASTtk.