library_construction_protocol: The total RNA for each sample was extracted with the miRNeasy Mini Kit (Qiagen). Then the libraries were prepared following the standard protocols with Optimal Dual-mode mRNA library Prep Kit (BGI-Shenzhen, China) for strand-specific mRNA sequencing, with two biological replicates for each samples. The mRNA libraries passing the quality control were processed on T7 platform (BGI-Shenzhen, China), generating paired-end 150 bp reads for mRNA.