library_construction_protocol: CB-derived HSPCs were cultured in chemically defined cytokine-free conditions for 10 days in the presence or absence of Lp-1. Viable cells (negative to Apotracker) were sorted with a 100 mm nozzle – on a BD FACSAria Fusion (BD Biosciences) - according to the surface expression of CD34+CD45RA-CD90+ markers. Sorted cells were collected in 1.5 ml Eppendorf tubes containing 100 μl of 1xDPBS. The sorted cells were counted with Trypan Blue solution 0.4% (GIBCO) and roughly 2x104 viable cells from each sample were utilized for the subsequent procedure (estimated recovery: 104 cells/sample). Libraries were prepared by Chromium Next GEM Single Cell 3' Reagent Kit v3.1 (10X Genomics) according to manufacturer's instructions.