design: KAPA Hyper Prep with RiboErase; The KAPA RNA HyperPrep Kit with RiboErase (HMR) is designed for both manual and automated NGS library construction from 25 ng – 1 µg of total RNA. The kit depletes both cytoplasmic (5S, 5.8S, 18S, and 28S), and mitochondrial (12S and 16S) rRNA species.