library_construction_protocol: ChIP-seq Extract Protocol:_x000B_25 ml of meiotic cell cultures were collected at various time points and fixed for 30 minutes in 1% formaldehyde, which was quenched with 125 mM glycine. ChIP samples were processed as described in Blitzblau et al., 2012. ChIP-seq Library Protocol:_x000B_ChIP samples were processed as described in Blitzblau et al., 2012. The quality of the libraries was assessed using the 2100 Bioanalyzer or 2200 Tapestation. Library concentrations were quantified using qPCR prior to pooling. Sequencing was performed on Illumina NextSeq 500 instruments at the NYU Biology Genomics Core.