title: CS/PEC/AMF
design: This study employs whole transcriptome sequencing (RNA-Seq) to elucidate the molecular responses of mouse colorectal tissues to abdominal radiotherapy, both with and without the protective intervention of chitosan-encapsulated pectin-amifostine (CS/PEC-AMF) nanoparticles. The goal is to identify key regulatory genes and pathways that mediate the protective effects of CS/PEC-AMF against radiation-induced cellular damage and carcinogenesis.