Efficient derivation of basal progenitor cells from human pluripotent stem cells for modeling esophageal development
We perfomred global transcriptomic profiling of E12.5 mouse embryonic esophageal epithelia, human fetal esophageal epthelia and human embryonic stem cell RUES2-derived esophageal progenitor cells. We found that these cells shared similar expression of NOTCH components including Jag1 and 2, Dll1, 3 and 4, and Notct1, 3, 4.