WES of Homo Sapiens: not available 65y. Female: Sample PR4091_T
Whole-exome capture libraries were constructed via the Agilent Sure-Select Human All Exon v2.0, 44Mb baited target with the Broad in-solution hybrid selection process. Enriched exome libraries were sequenced on the HiSeq 2000 platform (Illumina) to generate paired-end reads (2x76bp) to a goal of 150X mean target coverage (Broad Institute, Cambridge, MA). Targeted resequencing using a custom panel of 376 loci to a target coverage of 500X was performed using Ampliseq (Life Technologies).