Exome sequencing of Blepharospasm subject
the proband's genomic DNA was sheared , followed by processing with an Illumina (SanDiego, CA) paired-end library preparation kit. Target enrichment wasperformed with the Agilent SureSelect Human All Exon V5 kit (SantaClara, CA). Enriched DNA fragments were sequenced on Illumina'sHiSeq 2000 platform as paired-end reads