MBD-isolated Genome Sequencing (MiGS) for DNA methylome profiling
10 ng of MBD-isolated DNA per sample was processed with the ChIP-Seq Sample Prep Kit (Illumina) following manufacturer’s protocol to construct the sequencing libraries. Sequencing libraries were analyzed on the BioAnalyzer (Agilent), and a tight distribution of insert size around 120 bp was observed for all libraries. Each library was sequenced on the GAIIx.