Illumina HiSeq 2000 sequencing; Variation in chromatin accessibility in human kidney cancer links H3K36 methyltransferase loss with widespread RNA processing defects
Variation in chromatin accessibility in human kidney cancer links H3K36 methyltransferase loss with widespread RNA processing defects
Tumors and normal kidney stored at -80C. FAIRE was performed as described in Simon et al 2012, Nature Protocols. RNA-seq was performed on riboMinus-extracted RNA. Libraries were prepared using manufacturer's recommendations with TruSeq adapters or Illumina adapters.
Experimental Factor: genotype
Unknown
Experimental Factor: immunoprecipitate
N/A
Experimental Factor: disease
clear cell renal carcinoma