Illumina Genome Analyzer II paired end sequencing; Acquisition of somatic activating mutations in the vegf-pathway in cardiac angiosarcomas
Acquisition of somatic activating mutations in the vegf-pathway in cardiac angiosarcomas
Pot1 and damage response malfunction triggers acquisition of somatic activating mutations in the vegf-pathway in cardiac angiosarcomas DNA was extracted with DNeasy® Blood & Tissue Kit (Cat. No. 69504, Qiagen) following the manufacturer's instructions Exomes from selected tissues were captured and enriched using the SureSelect Human All Exon Kit (78Mb) (Agilent Technologies).
Experimental Factor: organism part
thyroid gland
Experimental Factor: disease
breast angiosarcoma; papillary follicular thyroid adenocarcinoma
Experimental Factor: sampling site
normal tissue