Illumina HiSeq 2500 paired end sequencing; RNA-seq of hippocampal samples from IL-18KO/APP/PS1 , WT, IL-18KO, and APP/PS1 mice.
RNA-seq of hippocampal samples from IL-18KO/APP/PS1 , WT, IL-18KO, and APP/PS1 mice.
Mice  were maintained in specific pathogen-free conditions and used in accordance with the Institutional Animal Care and Use Committee. RNA was purified from the hippocampus of mice. PolyA selected strand-specific libraries were generated with 1 μg of input RNA using the TruSeq Stranded mRNA Sample Prep Kit (Illumina). Samples were sized, quantified and validated on a Bioanalyzer.
Experimental Factor: genotype
APP/PS1