Whole genome data: Saccharomyces cerevisiae: 1B-D1606
Yeast cells were grown in YPD  to saturation. DNA extraction was performed according to Lada et al., 2013. Genomic DNA library was prepared using Ion Plus Fragment Library Kit,according to the manufacturer's recommendations (User Guide Publication Number 4471989, Revision N). Template-positive particles for genomic DNA sequencing were prepared using Ion PGM ™ Template OT2 400 Kit according to the user guide (Publication number MAN0007218, revision3.0). Sequencing was conducted using Ion PGM™ Sequencing 400 Kit and Ion 318™ Chip v2, following the manufacturer’s user guide (Publication Number MAN0007242, Revision 2.0).