Exponential growing DS1 Strain.
Phenol-chloroform RNA extractions were performed in duplicate for DS1-(hipQ)-strain type II persister cells from a pellet equivalent to an initial culture of 4.5 L for each biological replicate.  DNA degradation and total RNA purification were performed with a Qiagen RNeasy kit according to the manufacturer’s protocols (Qiagen, Hilden, Germany). RNASeq on each sample was performed at BGI on an Illumina HiSeq 2000 instrument using 2x101 paired-end tags and strand-specific chemistry.