DNA-seq of quadruplets 12-10
DNA was  extracted from blood collected according to standard protocols. We sequenced  each quadruplet together to obtain their identical genome sequence. We pooled  DNA from all four individuals of a quadruplet, except in the case of  quadruplet 16-30 where we could not get enough DNA from individual 16-301. An  average of 2.3g of DNA per quadruplet were sent for whole genome sequencing  at the New York Genome Centre (NYGC). Library preparation was Illumina TruSeq  Nano DNA, 450bp. Sequencing was done on the NovaSeq with 2x150bp. Coverage  depth was 30X.