miRNA mutation spectrum in eighteen hepatocellular carcinoma (HCC) cell lines with definite metastatic potentials and tropisms
In this study we investigate the miRNA expression profiles in 18 HCC cell lines with different metastatic potentials and organ-tropisms. Among them, HCC cell lines Huh7, Hep3B, SNU398, SMMC-7721£¬Bel-7402£¬HepG2£¬PLC-5 exhibit low metastasis abilities in nude mice model, while MHCC-97L, MHCC-97H, CSQT-1, CSQT-2, HCCLM3, LM1-S3, LM1-S4, LM1-S5, LM1-S11, LnM1-S11, LnM1-S13 exhibit high metastasis abilities in nude mice.