Single-cell RNAseq of lung tumor evolution (mouse, SS2): K_30w_ND_m1_T0_P3_S289
Single cell RNAseq of mouse lung tumors collected at different disease time points (2-30 weeks). Tumors are induced by AdSPC-Cre of in C57BL/6 x Sv129 mixed background mice from the following previously published strains: KrasLSL-G12D (Jackson et al., 2001), Trp53flox/flox (Marino et al., 2000), Rosa26LSL-tdTomato (Madisen et al., 2010), and Rosa26LSL-Luciferase (Safran et al., 2003). Tumors cells showing tdTom expression were sorted by FACS, captured and processed by SmartSeq2 protocol.