Whole exome sequencing of mus musculus acute myeloid leukemia
Mouse DNA libraries were prepared and captured using the Agilent SureSelectXT Mouse All Exon Kit according to the manufacturers instructions. In brief, DNA was fragmented on a Covaris S1 sonicator followed by end repair and phosphorylation.  Blunt fragments were adenylated, ligated to Illumina Y-adapters and PCR amplified. Bait hybridization proceeded for 48 hours, followed by recovery of captured exome fragments by PCR.
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