Exome-seq of adenoma and control
Target genes were selected from our previous study and COSMIC database. NimbleGen SeqCap EZ Choice XL Library (Roche NimbleGen, WI, USA) was used. (http://www.nimblegen.com/products/seqcap/ez/choice_xl/index.html). Each captured library was loaded on Hiseq2000 platform. The experiment was carried out following standard protocol. The reads were aligned against the human reference genome (GRCh37/hg19) using the Burrows-Wheeler Alignment tool (BWA).
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