STE-1
Understanding the genomic landscape of ALK fusion positive lung cancer
Tumor sample from a male never smoker diagnosed with stage IV non-small cell lung cancer; adenocarcinoma histology. We sequenced a cell line derived from this patient’s malignant pleural effusion prior to ALK inhibitor therapy. The novel cell line is called STE-1. This cell line harbors an EML4-ALK E13;A20 fusion. STE-1 was extracted with phenol followed by phenol:chloroform:isoamyl alcohol and precipitated with isopropanol.
Vanderbilt University
STE-1