E-MTAB-4679:SC_LALT
Illumina HiSeq 2000 paired end sequencing; Acquired TET2 mutation-linked clonal hematopoiesis in FPD/AML patient led to the development of pre-leukemic clone resulting independently in T2-ALL and AML-M0.
Acquired TET2 mutation-linked clonal hematopoiesis in FPD/AML patient led to the development of pre-leukemic clone resulting independently in T2-ALL and AML-M0.
SC_LALT
total hematopoietic cells were collected from bone marrow. The T-ALL blast population represents 58% of total population DNA was extracted using Qiagen Kit The fragment ends were repaired, “A” bases were added ends of the DNA fragments and adapters were ligated to the fragments. The adapter-ligated library was amplified using 4 to 6 cycles of PCR. 500 nanograms of the sample library were hybridized with the SureSelect biotinylated RNA library for 24 hours. Bound DNA was purified using streptavidin coated magnetic beads
INSERM U1170 Gustave Roussy
E-MTAB-4679:SC_LALT
Experimental Factor: T2-acute lymphoid leukemia (T2-ALL)
disease staging