RNA-seq of WT mouse: adult frontal cortex
We generated a Mbnl1-/-; Mbnl2 loxP/loxP; Nestin-Cre mouse line to deplete both Mbnl1 and Mbnl2 in the central nervous system (referred to Mbnl1/2 double-KO or dKO).  Deep RNA-seq was performed using high-quality RNA (RIN8) extracted from frontal cortices of adult Mbnl dKO and control mice, each group in triplicates using the standard Illumina TruSeq poly-dT protocol (PE 101-nt reads, ~60 million reads per sample).