Whole-genome sequencing of Z2 (healthy Tibetans)
Genomic DNAs were isolated from blood samples of each subject and randomly fragmented. Fragments of the desired length were gel purified. Adaptor ligation and DNA cluster preparation were performed with the library preparation kit according to the manufacturer’s instruction (Illumina). WGS was performed on the IlluminaHiseqXten platform with 150 base pairs (bps) paired-end reads.