Hi-C DNA sequencing of 20 pairs of adult S. haematobium worms
The DNA was sheared to ~350 bp mean fragment size, and sequencing libraries were generated using NEBNext Ultra enzymes and Illumina-compatible adapters. Biotin-containing fragments were then isolated using streptavidin beads before PCR enrichment of the library. This library was then used to sequence paired end reads on an Illumina HiSeq 2500 sequencing machine (2 _ 100 bp; using the rapid run protocol).