Illumina HiSeq 1000 paired end sequencing; Promoter Capture-HiC in Ring1a KO and Ring1a/b dKO mouse ES cells
Promoter Capture-HiC in Ring1a KO and Ring1a/b dKO mouse ES cells
Ring1A−/−;Ring1Bfl/fl;Rosa26::CreERT2 mESCs (Ring1A-KO) were cultured as described previously in Endoh et al. 2012 Hi-C was performed following (Lieberman-Aiden et al., Science, 2009, DOI: 10.1126/science.1181369 ) with modifications detailed in Schoenfelder et al.
Experimental Factor: genotype
Ring1a knock out
LIBRARY_STRAND
not applicable