Comparative analysis of the microbial profiles in supragingival plaque samples
To investigate the role of the oral microbiome and the impact of host and environmental factors on the initiation and progression of ECC, we studied the supragingival plaques of 14 twin pairs and a set of triplets with discordant caries phenotypes and of 15 mothers, applying the HOMINGS (Human Oral Microbe Identification using Next Generation Sequencing) technique.