The role of the gut microbiome in relation to low-calories artificial sweeteners on gut microbiome
Metagenomic libraries  were fragmented and indexed using Nextera XT DNA Library Prep Kit (Illumina  Inc., CA, USA), and Nextera XT Index kit (Illumina Inc.), respectively as per  manufacturers instructions. Amplicon libraries were then sequenced on the  Illumina HiSeq 4000 platform.