Exome-seq of cell lines with aquired Venetoclax resistance
Genomic DNA from Venetoclax sensitive and resistant B-cell lymphoma cell lines was extracted with DNeasy Blood and Tissue Kit (Cat No./ID: 69504; Qiagen, Hilden, GER) following the instructions and measured by NanoDrop 1000. Whole-exome sequencing was performed from genomic DNA, using the SureSelect Human All Exon V6 (Agilent, Santa Clara, CA, USA) target enrichment according to the manufacturers instructions.