Whole-Exome Seq of Homo sapiens : Human B-ALL Cells: Sample CHP156R-WES
Leukemic cells were engrafted into a patient-derived xenograft mouse model. Spleens containing engrafted human leukemic cells were harvested, and human cells were sorted using a mCD45- gate and hCD45+ or hCD19+ gate. Genomic DNA was purified, and whole-exome capture and genomic sequencing was performed by GENEWIZ using the Twist Human Exome Kit and Illumina HiSeq using the 2x150bp sequencing configuration.