Genomic  characterization of HPV+ HNSCC models
High molecular weight genomic DNA was isolated from human papilloma virus positive head and neck squamous cell carcinoma cell lines UM-SCC-47 and UM-SCC-104 as well as the human papilloma virus positive head and neck squamous cell carcinoma patient derived xenograft model, NCI-PDX-294, and used to generate 10x genomics based linked read sequencing libraries, which were and sequenced on an Illumina NovaSeq6000 with 300nt paired end run.