GSM5114298: K562_WT_ERRBS_R1; Homo sapiens; Bisulfite-Seq
High-molecular genomic DNA from K562 cells (n=3) was extracted using the DNA Isolation Kit for Cells and Tissues from Roche (Cat#118147700011). Multiplexed enhanced reduced-representation bisulfite sequencing (mERRBS) was performed as previously described by the University of Michigan Epigenomics Core (Garrett-Bakelman et al., 2015). Libraries were sequenced on a NovaSeq 6000 with 100bp single-end reads.